Active energy selective image detector for dual-energy computed radiography.

Abstract:

:A new energy selective detector for dual energy computed radiography has been developed that combines many of the advantages of x-ray tube voltage switching and single exposure double screen detectors. The new active detector utilizes electro-optical modulation of the response of the storage phosphor screens to allow dual exposure acquisition with no motion of the screens. Electro-optical modulation can be done rapidly so the detector can acquire the voltage switched images in a short enough time to minimize patient motion artifacts. Voltage switching produces effective detected energy spectra that result in much lower noise for a given patient dose than the effective spectra of double screen detectors. In this paper the new concept is described, optimal voltages and filter materials are determined by computer simulations, and the active detector performance is compared to other energy selective detectors. The new detector provides over 30 times better signal to noise ratio squared (SNR2) for the same dose and over five times better SNR2 for the same x-ray tube loading than a double screen detector. The effects of incomplete erasure of the x-ray exposures are determined quantitatively. With achievable erasing fractions, the SNR2 is over 20 times better for the same dose and over three times better for constant tube loading than a double screen detector. The active detector is also compared to mechanical screen switching. Mechanical switching provides somewhat better SNR2 for the same dose, approximately 1.1 times the active detector SNR2 at optimal x-ray tube voltages. The performance is compared with highly absorbing back screens. If these are used in both the active and passive detectors, both detectors' quality factors increase, but the advantage of the active detector over the passive detector decreases with large back screen thicknesses.

journal_name

Med Phys

journal_title

Medical physics

authors

Alvarez RE

doi

10.1118/1.597831

subject

Has Abstract

pub_date

1996-10-01 00:00:00

pages

1739-48

issue

10

eissn

0094-2405

issn

2473-4209

journal_volume

23

pub_type

杂志文章
  • Systematic calibration of an integrated x-ray and optical tomography system for preclinical radiation research.

    abstract:PURPOSE:The cone beam computed tomography (CBCT) guided small animal radiation research platform (SARRP) has been developed for focal tumor irradiation, allowing laboratory researchers to test basic biological hypotheses that can modify radiotherapy outcomes in ways that were not feasible previously. CBCT provides exce...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4914860

    authors: Yang Y,Wang KK,Eslami S,Iordachita II,Patterson MS,Wong JW

    更新日期:2015-04-01 00:00:00

  • Low-dose CT reconstruction using spatially encoded nonlocal penalty.

    abstract:PURPOSE:Computed tomography (CT) is one of the most used imaging modalities for imaging both symptomatic and asymptomatic patients. However, because of the high demand for lower radiation dose during CT scans, the reconstructed image can suffer from noise and artifacts due to the trade-off between the image quality and...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12523

    authors: Kim K,El Fakhri G,Li Q

    更新日期:2017-10-01 00:00:00

  • Temporal and spectral imaging with micro-CT.

    abstract:PURPOSE:Micro-CT is widely used for small animal imaging in preclinical studies of cardiopulmonary disease, but further development is needed to improve spatial resolution, temporal resolution, and material contrast. We present a technique for visualizing the changing distribution of iodine in the cardiac cycle with du...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4736809

    authors: Johnston SM,Johnson GA,Badea CT

    更新日期:2012-08-01 00:00:00

  • X-ray-transmission computed tomography.

    abstract::The immediate goal of clinically based x-ray-transmission computed tomography (CT) is to provide a measurement of the x-ray linear attenuation coefficient in cross section with the ultimate goal of impacting on patient management and care. To do this with the accuracy needed for clinical goals requires the careful int...

    journal_title:Medical physics

    pub_type: 杂志文章,评审

    doi:10.1118/1.594381

    authors: McCullough EC,Payne JT

    更新日期:1977-03-01 00:00:00

  • Analysis and correction of imperfections in the image intensifier-TV-digitizer imaging chain.

    abstract::Image intensifier-television-video digitizer (IITVD) systems are commonly used for digital planar image acquisition in radiology. However, the well-known distortions inherent in these systems limit their utility in research and in some clinical applications where quantitatively correct images are required. Software co...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596718

    authors: Boone JM,Seibert JA,Barrett WA,Blood EA

    更新日期:1991-03-01 00:00:00

  • Poster - Thur Eve - 77: Coordinate transformation from DICOM to DOSXYZnrc.

    abstract::DICOM format is the de facto standard for communications between therapeutic and diagnostic modalities. A plan generated by a treatment planning system (TPS) is often exported to DICOM format. BEAMnrc/DOSXYZnrc is a widely used Monte Carlo (MC) package for beam and dose simulations in radiotherapy. It has its own defi...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4740186

    authors: Zhan L,Jiang R,Osei EK

    更新日期:2012-07-01 00:00:00

  • Determination of the quality index (Q) for photon beams at arbitrary field sizes.

    abstract:PURPOSE:A commonly used beam quality index (Q) for high-energy photon beams is the tissue phantom ratio (TPR20,10) for a square field of 10 x 10 cm2 and SDD of 100 cm. On some specialized radiotherapy treatment equipment such a reference collimator setting is not achievable. Likewise a flat beam profile, not explicitly...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3197062

    authors: Sauer OA

    更新日期:2009-09-01 00:00:00

  • Spacing nomograph for interstitial implants of 125I seeds.

    abstract::Permanent implants of 125I seeds at Memorial Sloan-Kettering Cancer Center are performed by the method of "dimension averaging" to determine the total activity to be implanted; that is, the activity (in mCi) is taken to be five times the average dimension (in cm) of the target region. A nomograph has recently been dev...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.594269

    authors: Anderson LL

    更新日期:1976-01-01 00:00:00

  • A Monte Carlo investigation of low-Z target image quality generated in a linear accelerator using Varian's VirtuaLinac.

    abstract:PURPOSE:The focus of this work was the demonstration and validation of VirtuaLinac with clinical photon beams and to investigate the implementation of low-Z targets in a TrueBeam linear accelerator (Linac) using Monte Carlo modeling. METHODS:VirtuaLinac, a cloud based web application utilizing Geant4 Monte Carlo code,...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4861818

    authors: Parsons D,Robar JL,Sawkey D

    更新日期:2014-02-01 00:00:00

  • SU-E-T-96: Energy Dependence of the New GafChromic- EBT3 Film's Dose Response-Curve.

    abstract:PURPOSE:To study and compare the dose response curves of the new GafChromic EBT3 film for megavoltage and kilovoltage x-ray beams, with different spatial resolution. METHODS:Two sets of EBT3 films (lot#A101711-02) were exposed to each x-ray beam (6MV, 15MV and 50kV) at 8 dose values (50-3200cGy). The megavoltage beams...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735153

    authors: Chiu-Tsao S,Massillon-Jl G,Domingo-Muñoz I,Chan M

    更新日期:2012-06-01 00:00:00

  • Comparison of quantitative Y-90 SPECT and non-time-of-flight PET imaging in post-therapy radioembolization of liver cancer.

    abstract:PURPOSE:Radioembolization with yttrium-90 microspheres may be optimized with patient-specific pretherapy treatment planning. Dose verification and validation of treatment planning methods require quantitative imaging of the post-therapy distribution of yttrium-90 (Y-90). Methods for quantitative imaging of Y-90 using b...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4962472

    authors: Yue J,Mauxion T,Reyes DK,Lodge MA,Hobbs RF,Rong X,Dong Y,Herman JM,Wahl RL,Geschwind JH,Frey EC

    更新日期:2016-10-01 00:00:00

  • Controlled mold geometry for surgical deficit treatment planning.

    abstract::The relatively precise placement of brachytherapy sources afforded by stereotactic frames for brain implants is not generally achievable for other sites, which lack the fixed geometry of the cranium and its contents. An exception is a source-containing rigid mold that delivers brachytherapy when inserted securely in a...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597454

    authors: Anderson LL,Zlotolow IM,McCormick B,Harrison LB

    更新日期:1995-03-01 00:00:00

  • Anatomy-based three-dimensional dose optimization in brachytherapy using multiobjective genetic algorithms.

    abstract::In conventional dose optimization algorithms, in brachytherapy, multiple objectives are expressed in terms of an aggregating function which combines individual objective values into a single utility value, making the problem single objective, prior to optimization. A multiobjective genetic algorithm (MOGA) was develop...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.598697

    authors: Lahanas M,Baltas D,Zamboglou N

    更新日期:1999-09-01 00:00:00

  • Measurement of x-ray attenuation coefficients of aqueous solutions of indocyanine green and glycated chitosan.

    abstract::We report our experimental results of measurements of x-ray attenuation coefficients of aqueous solutions of a light absorbing dye, indocyanine green, and an immunoadjuvant, glycated chitosan. In the treatment of metastatic tumors in rats using a novel laser immunotherapy these solutions were administered in situ. The...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.598633

    authors: Xu F,Liu H,Wu X,Jiang H,Nordquist RE,Chen WR

    更新日期:1999-07-01 00:00:00

  • Technical Note: Mobile accelerator guidance using an optical tracker during docking in IOERT procedures.

    abstract:PURPOSE:Intraoperative electron radiation therapy (IOERT) involves the delivery of a high radiation dose during tumor resection in a shorter time than other radiation techniques, thus improving local control of tumors. However, a linear accelerator device is needed to produce the beam safely. Mobile linear accelerators...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12482

    authors: Marinetto E,Victores JG,García-Sevilla M,Muñoz M,Calvo FÁ,Balaguer C,Desco M,Pascau J

    更新日期:2017-10-01 00:00:00

  • Development and clinical implementation of semi-automated treatment planning including 3D printable applicator holders in complex skin brachytherapy.

    abstract:PURPOSE:High-dose-rate brachytherapy (HDR-BT) is a treatment option for malignant skin diseases compared to external beam radiation therapy, HDR-BT provides improved target coverage, better organ sparing, and has comparable treatment times. This is especially true for large clinical targets with complex topologies. To ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.13975

    authors: Guthier CV,Devlin PM,Harris TC,O'Farrell DA,Cormack RA,Buzurovic I

    更新日期:2020-03-01 00:00:00

  • Technical Note: ADAM PETer - An anthropomorphic, deformable and multimodality pelvis phantom with positron emission tomography extension for radiotherapy.

    abstract:OBJECTIVE:To develop an anthropomorphic, deformable and multimodal pelvis phantom with positron emission tomography extension for radiotherapy (ADAM PETer). METHODS:The design of ADAM PETer was based on our previous pelvis phantom (ADAM) and extended for compatibility with PET and use in 3T magnetic resonance imaging ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.14597

    authors: Gillmann C,Homolka N,Johnen W,Runz A,Echner G,Pfaffenberger A,Mann P,Schneider V,Hoffmann AL,Troost EGC,Koerber SA,Kotzerke J,Beuthien-Baumann B

    更新日期:2020-11-18 00:00:00

  • Deconvolution techniques for removing the effects of chemical shift in 19F nuclear magnetic resonance imaging of perfluorocarbon compounds.

    abstract::Nuclear magnetic resonance (NMR) imaging of perfluorocarbon (PFC) emulsions and neat liquids has shown potential for in vivo oxygen imaging in blood and organ tissue. PFC compounds exhibit complicated NMR spectra caused by chemical shifts and spin-spin couplings which can lead to artifacts and degraded spatial resolut...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.595960

    authors: Busse LJ,Thomas SR,Pratt RG,Clark LC Jr,Ackerman JL,Samaratunga RC,Hoffmann RE

    更新日期:1986-07-01 00:00:00

  • Optical spectroscopy of the breast in premenopausal women reveals tissue variation with changes in age and parity.

    abstract:PURPOSE:Variations during breast tissue development can influence later breast cancer risk. In particular, prolonged nulliparity increases risk. The authors used optical spectroscopy to compare breast tissue in 115 nulliparous women aged 31-40 (group 2) to 140 nulliparous women aged 18-21 (group 1), and also to 36 paro...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3276737

    authors: Knight JA,Blackmore KM,Wong J,Tharmalingam S,Lilge L

    更新日期:2010-02-01 00:00:00

  • Effects of point configuration on the accuracy in 3D reconstruction from biplane images.

    abstract::Two or more angiograms are being used frequently in medical imaging to reconstruct locations in three-dimensional (3D) space, e.g., for reconstruction of 3D vascular trees, implanted electrodes, or patient positioning. A number of techniques have been proposed for this task. In this simulation study, we investigate th...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2008467

    authors: Dmochowski J,Hoffmann KR,Singh V,Xu J,Nazareth DP

    更新日期:2005-09-01 00:00:00

  • Absorbed-dose beam quality conversion factors for cylindrical chambers in high energy photon beams.

    abstract::Recent working groups of the AAPM [Almond et al., Med. Phys. 26, 1847 (1999)] and the IAEA (Andreo et al., Draft V.7 of "An International Code of Practice for Dosimetry based on Standards of Absorbed Dose to Water," IAEA, 2000) have described guidelines to base reference dosimetry of high energy photon beams on absorb...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1328081

    authors: Seuntjens JP,Ross CK,Shortt KR,Rogers DW

    更新日期:2000-12-01 00:00:00

  • SU-E-I-16: Automated Liver Segmentation Method for CBCT Dataset by Probabilistic Atlas Construction.

    abstract:PURPOSE:The aiming is getting accurate liver contour structures automatically for following adaptive radiation therapy in daily CBCT images which is very low-contrast comparing the planning CT. METHODS:Probabilistic atlas is constructed by 50 intravenous contrast planning CT images by iterative affine registration pro...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4734730

    authors: Li D,Li H,Yin Y,Chen J

    更新日期:2012-06-01 00:00:00

  • Correcting kernel tilting and hardening in convolution/superposition dose calculations for clinical divergent and polychromatic photon beams.

    abstract::To account for clinical divergent and polychromatic photon beams, we have developed kernel tilting and kernel hardening correction methods for convolution dose calculation algorithms. The new correction methods were validated by Monte Carlo simulation. The accuracy and computation time of the our kernel tilting and ke...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597960

    authors: Liu HH,Mackie TR,McCullough EC

    更新日期:1997-11-01 00:00:00

  • On calculating kerma, collision kerma and radiative yields.

    abstract:PURPOSE:To study the relationships between dose (D), kerma (K), and collision kerma ( K col ) in photon beams and to investigate total radiative yields for electrons and positrons as a functio...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.13744

    authors: Rogers DWO,Townson RW

    更新日期:2019-11-01 00:00:00

  • Computerized analysis of mammographic microcalcifications in morphological and texture feature spaces.

    abstract::We are developing computerized feature extraction and classification methods to analyze malignant and benign microcalcifications on digitized mammograms. Morphological features that described the size, contrast, and shape of microcalcifications and their variations within a cluster were designed to characterize microc...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.598389

    authors: Chan HP,Sahiner B,Lam KL,Petrick N,Helvie MA,Goodsitt MM,Adler DD

    更新日期:1998-10-01 00:00:00

  • Breast tumor segmentation in 3D automatic breast ultrasound using Mask scoring R-CNN.

    abstract:PURPOSE:Automatic breast ultrasound (ABUS) imaging has become an essential tool in breast cancer diagnosis since it provides complementary information to other imaging modalities. Lesion segmentation on ABUS is a prerequisite step of breast cancer computer-aided diagnosis (CAD). This work aims to develop a deep learnin...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.14569

    authors: Lei Y,He X,Yao J,Wang T,Wang L,Li W,Curran WJ,Liu T,Xu D,Yang X

    更新日期:2020-10-30 00:00:00

  • MOSFET dosimetry for microbeam radiation therapy at the European Synchrotron Radiation Facility.

    abstract::Preclinical experiments are carried out with approximately 20-30 microm wide, approximately 10 mm high parallel microbeams of hard, broad-"white"-spectrum x rays (approximately 50-600 keV) to investigate microbeam radiation therapy (MRT) of brain tumors in infants for whom other kinds of radiotherapy are inadequate an...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1562169

    authors: Bräuer-Krisch E,Bravin A,Lerch M,Rosenfeld A,Stepanek J,Di Michiel M,Laissue JA

    更新日期:2003-04-01 00:00:00

  • Absolute depth-dose-rate measurements for an 192Ir HDR brachytherapy source in water using MOSFET detectors.

    abstract::Reported MOSFET measurements concern mostly external radiotherapy and in vivo dosimetry. In this paper, we apply the technique for absolute dosimetry in the context of HDR brachytherapy using an 192Ir source. Measured radial dose rate distributions in water for different planes perpendicular to the source axis are pre...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2198168

    authors: Zilio VO,Joneja OP,Popowski Y,Rosenfeld A,Chawla R

    更新日期:2006-06-01 00:00:00

  • Interleaf leakage for 5 and 10 mm dynamic multileaf collimation systems incorporating patient motion.

    abstract::Use of dynamic multileaf collimation (DMLC) for intensity modulated radiation therapy (IMRT) is accelerating. Delivery systems have the ailment of interleaf leakage (IL). This is compounded by the inefficiency of IMRT delivery, estimated to be a factor of 5 for DMLC. With IL on the order of 4%, it is possible to deliv...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1388216

    authors: Klein EE,Low DA

    更新日期:2001-08-01 00:00:00

  • Maximum likelihood analysis of free-response receiver operating characteristic (FROC) data.

    abstract::Receiver operating characteristic (ROC) methodology is widely used in evaluating medical imaging modalities. While appropriate in some cases, it has several drawbacks when the detection task, e.g., nodule detection, involves localizing the abnormality. Free-response receiver operating characteristic (FROC) methodology...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596358

    authors: Chakraborty DP

    更新日期:1989-07-01 00:00:00