Abstract:
:Nuclear magnetic resonance (NMR) imaging of perfluorocarbon (PFC) emulsions and neat liquids has shown potential for in vivo oxygen imaging in blood and organ tissue. PFC compounds exhibit complicated NMR spectra caused by chemical shifts and spin-spin couplings which can lead to artifacts and degraded spatial resolution of resulting NMR images. To correct for the chemical shift artifacts, the technique of spectral deconvolution has been applied to NMR imaging of PFC compounds. The temporal filter for this process can be directly applied to raw free induction decay data in projection reconstruction or to spin-echo data in two-dimensional Fourier transform imaging techniques. The effect of chemical shift artifacts was demonstrated through the NMR imaging of two PFC compounds (F-tributylamine and F-decalin) in phantoms. Methods are presented and demonstrated which allow the chemical shift artifacts to be removed and true images of the spatial distribution of the PFC's to be recovered.
journal_name
Med Physjournal_title
Medical physicsauthors
Busse LJ,Thomas SR,Pratt RG,Clark LC Jr,Ackerman JL,Samaratunga RC,Hoffmann REdoi
10.1118/1.595960subject
Has Abstractpub_date
1986-07-01 00:00:00pages
518-24issue
4eissn
0094-2405issn
2473-4209journal_volume
13pub_type
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