Abstract:
BACKGROUND:The most effective treatment for patients with esophageal small cell carcinoma has not yet been established because of the overall extremely poor prognosis regardless of the mode of treatment. The role of esophagectomy has been controversial in the management of patients with this disease. METHODS:The clinicopathologic characteristics of 13 patients with primary esophageal small cell carcinoma were retrospectively studied and the prognostic significance of various factors with respect to esophagectomy were evaluated. RESULTS:Lymph node metastases and distant metastases were found at the time of presentation in 92.3 and 46.2%, respectively. Two of nine patients treated by surgical resection for local-regional disease survived >5 years after radical esophagectomy with a projected 5-year survival rate of 22.2%. The remaining 4/13 patients were treated by nonsurgical modalities, but died of the disease within 10 months. A significant difference (P < 0.05) was detected between the survival curves of the two groups of patients. CONCLUSION:Radical esophagectomy may be an effective treatment modality in improving survival and the odds of a cure in patients with local-regional small cell carcinoma of the esophagus.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Nishimaki T,Suzuki T,Nakagawa S,Watanabe K,Aizawa K,Hatakeyama Kdoi
10.1002/(sici)1096-9098(199702)64:2<130::aid-jso8>subject
Has Abstractpub_date
1997-02-01 00:00:00pages
130-4issue
2eissn
0022-4790issn
1096-9098pii
10.1002/(SICI)1096-9098(199702)64:2<130::AID-JSO8>journal_volume
64pub_type
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