Screening and surgical prophylaxis for hereditary cancer syndromes with high risk of endometrial and ovarian cancer.

Abstract:

:In the era of advanced cancer genomics, our recognition of hereditary cancer mutations continues to increase. Two of these conditions, which carry an increased risk of female cancers including endometrial, ovarian, breast, are hereditary breast and ovarian cancer syndrome and Lynch syndrome. Risk-reducing surgery, such as mastectomy, salpingo-oophorectomy, and hysterectomy may decrease cancer risk for mutation carriers. Background, indications, techniques, and consequences of these surgical procedures are reviewed.

journal_name

J Surg Oncol

authors

Bercow AS,Eisenhauer EL

doi

10.1002/jso.25645

subject

Has Abstract

pub_date

2019-10-01 00:00:00

pages

864-872

issue

5

eissn

0022-4790

issn

1096-9098

journal_volume

120

pub_type

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