Abstract:
:Sibutramine is an antiobesity drug that inhibits the reuptake of serotonin and noradrenalin in the hypothalamus. A 37-year-old Korean man presented to the emergency room for the oral intake of 280 mg of sibutramine. The patient was in thyrotoxic state. The (99m)Technetium-pertechnetate thyroid scan showed irregular uptake of radioisotope and thyroid-stimulating hormone receptor antibody and thyroperoxidase antibody were negative. Thyroid function normalized after that. The patient had transient thyrotoxicosis with thyroiditis. We report a case of thyrotoxicosis accompanied by thyroiditis resulting from the intentional overdose of sibutramine.
journal_name
Hum Exp Toxicoljournal_title
Human & experimental toxicologyauthors
Kim SK,Lee SM,Yoo SS,Hahm JR,Jung JH,Kim HS,Kim S,Chung SI,Jung TSdoi
10.1177/0960327112468907subject
Has Abstractpub_date
2013-08-01 00:00:00pages
890-2issue
8eissn
0960-3271issn
1477-0903pii
0960327112468907journal_volume
32pub_type
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