Abstract:
:The role of genetic factors in determining risk for status epilepticus (SE) was examined in twins identified using the population-based Virginia Twin Registry. Concordance rates for SE were 0.38 for monozygotic (MZ) and 0.00 for dizygotic (DZ) twins, with the rate in MZs being significantly increased over DZs. The prevalence of SE in MZ co-twins of affected individuals was as high as 0.55. Clinical presentation of SE was evaluated, and no association was found between occurrence of SE and age at onset or seizure etiology. Genetic factors contribute to risk for SE.
journal_name
Neurologyjournal_title
Neurologyauthors
Corey LA,Pellock JM,Boggs JG,Miller LL,DeLorenzo RJdoi
10.1212/wnl.50.2.558subject
Has Abstractpub_date
1998-02-01 00:00:00pages
558-60issue
2eissn
0028-3878issn
1526-632Xjournal_volume
50pub_type
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