Two randomized migraine studies of galcanezumab: Effects on patient functioning and disability.

abstract：:Postexercise facilitation (PEF) with clinical reflexes, H-reflex, and T-reflexes at the ankle and knee was systematically studied in 16 patients with Lambert-Eaton myasthenic syndrome (LEMS). PEF was observed in ankle and knee deep tendon reflexes in five patients, in H-reflex in three patients, and in T-reflexes in s...

journal_title：Neurology

authors： Odabasi Z,Demirci M,Kim DS,Lee DK,Ryan HF,Claussen GC,Tseng A,Oh SJ

更新日期：2002-10-08 00:00:00

abstract：OBJECTIVE:To examine metabolism during exercise in 2 patients with muscle phosphorylase kinase (PHK) deficiency and to further define the phenotype of this rare glycogen storage disease (GSD). METHODS:Patient 1 (39 years old) had mild exercise-induced forearm pain, and EMG showed a myopathic pattern. Patient 2 (69 yea...

journal_title：Neurology

authors： Preisler N,Orngreen MC,Echaniz-Laguna A,Laforet P,Lonsdorfer-Wolf E,Doutreleau S,Geny B,Akman HO,Dimauro S,Vissing J

更新日期：2012-01-24 00:00:00

abstract：OBJECTIVE:To determine whether serum Zic4 antibodies associate with paraneoplastic neurologic disorders (PND) and small-cell lung cancer (SCLC), and the association of these antibodies with other onconeuronal immunities associated with SCLC. DESIGN/METHODS:The authors studied 498 patients (215 with PND and 283 without...

journal_title：Neurology

authors： Bataller L,Wade DF,Graus F,Stacey HD,Rosenfeld MR,Dalmau J

更新日期：2004-03-09 00:00:00

abstract：OBJECTIVE:To investigate whether the correlation of age and sex with the risk of recurrence and death seen in patients with previous ischemic stroke is also evident in patients with embolic stroke of undetermined source (ESUS). METHODS:We pooled datasets of 11 stroke registries from Europe and America. ESUS was define...

journal_title：Neurology

authors： Ntaios G,Lip GYH,Vemmos K,Koroboki E,Manios E,Vemmou A,Rodríguez-Campello A,Cuadrado-Godia E,Roquer J,Arnao V,Caso V,Paciaroni M,Diez-Tejedor E,Fuentes B,Pérez Lucas J,Arauz A,Ameriso SF,Pertierra L,Gómez-Schneider M

更新日期：2017-08-08 00:00:00

abstract：:Heterozygous PAX6 mutation is associated with an absent or hypoplastic anterior commissure and a reduction in the area of the corpus callosum. The authors found deficient auditory interhemispheric transfer in a 53-year-old woman with a PAX6 mutation who had an absent anterior commissure but normal callosal volume. ...

journal_title：Neurology

authors： Bamiou DE,Musiek FE,Sisodiya SM,Free SL,Mitchell TN,Davies RA

更新日期：2004-02-10 00:00:00

abstract：:Neurologists are prescribing intravenous immunoglobulin (IVIg) with increasing frequency to treat many neurologic conditions that have a proven or presumed autoimmune or inflammatory pathogenesis. Although IVIg is not FDA approved for any neurologic condition, physicians can safely prescribe it for several disorders w...

journal_title：Neurology

authors： Donofrio PD,Busis NA

更新日期：2002-12-24 00:00:00

abstract：OBJECTIVE:To demonstrate that progress has been made in unifying brain death determination guidelines in the last decade by directly comparing the policies of the US News and World Report's top 50 ranked neurologic institutions from 2006 and 2015. METHODS:We solicited official hospital guidelines in 2015 from these to...

journal_title：Neurology

authors： Wang HH,Varelas PN,Henderson GV,Wijdicks EF,Greer DM

更新日期：2017-02-07 00:00:00

abstract：:We have identified large-scale deletions in muscle mitochondrial DNA (mtDNA) in seven of seven patients with Kearns-Sayre syndrome (KSS). We found no detectable deletions in the mtDNA of ten non-KSS patients with other mitochondrial myopathies or encephalomyopathies, or three normal controls. The deletions ranged in s...

journal_title：Neurology

authors： Zeviani M,Moraes CT,DiMauro S,Nakase H,Bonilla E,Schon EA,Rowland LP

更新日期：1988-09-01 00:00:00

abstract：:Study of diagnostic practice is necessary to optimize neurologists' clinical performance and ensure patient safety. To our knowledge, this report is the first set of systematic observations of diagnostic practices of community neurologists in their clinics. The study consisted of six 2-week periods of in situ observat...

journal_title：Neurology

authors： Dhand A,Engstrom J,Dhaliwal G

更新日期：2013-10-15 00:00:00

abstract：:We determined the horizontal and vertical components of brain displacement on coronal MRIs in 10 patients with acute supratentorial masses. The vertical distances from the superior sagittal sinus to the pontomesencephalic junction (PMJ) and from the vertical midline of the brain to the PMJ did not differ from measurem...

journal_title：Neurology

authors： Ropper AH

更新日期：1989-05-01 00:00:00

abstract：:We report a patient with rostral hypothalamic damage that significantly disrupted temporal patterning of the sleep-wake cycle, body temperature, and cognitive and behavioral functioning. The findings suggest that the suprachiasmatic region of the hypothalamus is important for the circadian control of human behavior, a...

journal_title：Neurology

authors： Cohen RA,Albers HE

更新日期：1991-05-01 00:00:00

abstract：:Acute chorea in a child followed ingestion of pemoline mesylate. In guinea pigs, in an experimental model of chorea, chronic administration of pemoline induced behavioral supersensitivity to other dopaminergic agonists. Pemoline is similar to both d-amphetamine and methylphenidate in altering central dopaminergic sens...

journal_title：Neurology

authors： Nausieda PA,Koller WC,Weiner WJ,Klawans HL

更新日期：1981-03-01 00:00:00

abstract：OBJECTIVE:To assess the clinical implications and the pathophysiologic determinants of interictal bitemporal hypometabolism (BTH) in temporal lobe epilepsy (TLE) not associated with bilateral MRI abnormalities or intracranial space-occupying lesions. METHODS:The authors compared the clinical, interictal, and ictal EEG...

journal_title：Neurology

authors： Koutroumanidis M,Hennessy MJ,Seed PT,Elwes RD,Jarosz J,Morris RG,Maisey MN,Binnie CD,Polkey CE

更新日期：2000-05-09 00:00:00

abstract：:We examined the baseline characteristics of patients in the Ticlopidine Aspirin Stroke Study (TASS) to determine if the effects of the two treatments in preventing stroke differed in various subgroups. Patients with the following characteristics did less well on aspirin: elevated creatinine, hypertension or diabetes r...

journal_title：Neurology

authors： Grotta JC,Norris JW,Kamm B

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:The best treatment for polyneuropathy associated with IgM monoclonal gammopathy (MGUS) is unknown. Oral cyclophosphamide combined with prednisone showed limited efficacy in a previous open label pilot study. We therefore performed a double-blind, randomized, placebo-controlled study of combined oral cyclopho...

journal_title：Neurology

authors： Niermeijer JM,Eurelings M,van der Linden MW,Lokhorst HM,Franssen H,Fischer K,Teunissen LL,van den Berg LH,Schobben F,Wokke JH,Notermans NC

更新日期：2007-07-03 00:00:00

abstract：OBJECTIVE:To explore the inflammatory processes in the pathogenesis of psychiatric symptoms and the prognostic value of psychiatric comorbidities in multiple sclerosis (MS). METHODS:Four hundred five patients with relapsing-remitting (RR) MS underwent psychiatric evaluation by means of Beck Depression Inventory II (BD...

journal_title：Neurology

authors： Rossi S,Studer V,Motta C,Polidoro S,Perugini J,Macchiarulo G,Giovannetti AM,Pareja-Gutierrez L,Calò A,Colonna I,Furlan R,Martino G,Centonze D

更新日期：2017-09-26 00:00:00

abstract：:In children, seizures associated with status epilepticus (SE) include a number of types that are age-related. These types of seizures are not associated with SE in older patients. Likewise, etiologies of SE in children are also unique to this patient population, in particular those responsible for SE in the neonate. C...

journal_title：Neurology

authors： Lockman LA

更新日期：1990-05-01 00:00:00

abstract：OBJECTIVE:Twenty-eight percent of patients with the Guillain-Barré syndrome remain able to walk unaided. Studying patients with the mild form of Guillain-Barré syndrome can further contribute to knowledge of the spectrum of the syndrome and explore whether this subgroup may need treatment with IV immunoglobulin. METHO...

journal_title：Neurology

authors： Van Koningsveld R,Schmitz PI,Ang CW,Groen J,Osterhaus AD,Van der Meché FG,Van Doorn PA

更新日期：2002-02-26 00:00:00

abstract：:Regional cerebral glucose metabolism was studied in 16 patients with idiopathic torticollis, using positron emission tomography. Analysis of subcortical regions revealed no consistent focal abnormality of cerebral metabolic rate for glucose, but there was a bilateral breakdown of the normal relationships between the t...

journal_title：Neurology

authors： Stoessl AJ,Martin WR,Clark C,Adam MJ,Ammann W,Beckman JH,Bergstrom M,Harrop R,Rogers JG,Ruth TJ

更新日期：1986-05-01 00:00:00

abstract：OBJECTIVES:To investigate capacity to consent to medical treatment (competency) in cognitively impaired patients with PD. BACKGROUND:Although competency has been studied empirically in patients with cortical dementia (AD), no empirical studies have examined competency in patients with PD or other subcortical neurodege...

journal_title：Neurology

authors： Dymek MP,Atchison P,Harrell L,Marson DC

更新日期：2001-01-09 00:00:00

abstract：OBJECTIVE:In children with and without infantile spasms, this study determined brain volumes and cell densities in epilepsy surgery patients with tuberous sclerosis complex (TSC) and cortical dysplasia with balloon cells (CD). METHODS:We compared TSC (n = 18) and CD (n = 17) patients with normal/autopsy controls (n = ...

journal_title：Neurology

authors： Chandra PS,Salamon N,Nguyen ST,Chang JW,Huynh MN,Cepeda C,Leite JP,Neder L,Koh S,Vinters HV,Mathern GW

更新日期：2007-02-06 00:00:00

abstract：:Since the introduction of computed tomography (CT), there have been numerous reports of brain abscess treated successfully without surgery. Because pathologic confirmation was lacking in these patients, diagnosis was based on CT abnormalities, usually ring enhancement. However, our recent clinical experience and the e...

journal_title：Neurology

authors： Dobkin JF,Healton EB,Dickinson PC,Brust JC

更新日期：1984-02-01 00:00:00

abstract：BACKGROUND:Cerebral microbleeds are known to be indicative of bleeding-prone microangiopathy and may predict incident intracerebral hemorrhage (ICH). In this study, we investigated whether microbleeds are associated with the incidence of warfarin-related ICH. METHODS:Twenty-four patients with ICH while on outpatient t...

journal_title：Neurology

authors： Lee SH,Ryu WS,Roh JK

更新日期：2009-01-13 00:00:00

abstract：OBJECTIVES:This study examines the anatomical correlates of naming vs recognizing faces using a novel measure that utilizes culturally relevant and age-appropriate items, the Northwestern University Famous Faces (NUFFACE) Test, in primary progressive aphasia (PPA), a syndrome characterized by progressive language defic...

journal_title：Neurology

authors： Gefen T,Wieneke C,Martersteck A,Whitney K,Weintraub S,Mesulam MM,Rogalski E

更新日期：2013-08-13 00:00:00

abstract：OBJECTIVE:We sought to identify intracranial EEG patterns characteristic of epileptogenic tubers and to understand the contribution of perituberal cortex. METHODS:Twenty-three intracranial EEG monitoring studies were reviewed from 17 children aged 1.3-7.7 years with tuberous sclerosis complex and intractable multifoca...

journal_title：Neurology

authors： Mohamed AR,Bailey CA,Freeman JL,Maixner W,Jackson GD,Harvey AS

更新日期：2012-12-04 00:00:00

abstract：:Many studies have demonstrated that dipyridamole is not purely an antiplatelet agent but also exerts its antithrombotic properties through the vessel wall. Using a laboratory model in which bovine endothelial cells are seeded to form a subendothelial matrix (SEM), investigators have shown that dipyridamole enhances th...

journal_title：Neurology

authors： Eisert WG

更新日期：2001-01-01 00:00:00

abstract：:We performed serial baseline and gadolinium (Gd)-DTPA-enhanced MRI in 4 patients with definite multiple sclerosis. Studies were performed every month for a total of 4 scans. We obtained short TR/short TE sequences at 10 and 60 minutes after Gd-DTPA injection. All patients had multiple hyperintense lesions seen on base...

journal_title：Neurology

authors： Bastianello S,Pozzilli C,Bernardi S,Bozzao L,Fantozzi LM,Buttinelli C,Fieschi C

更新日期：1990-04-01 00:00:00

abstract：:Gilles de la Tourette's syndrome (TS) is a familial disorder that is often exacerbated by stress or fatigue. Here we present a family of a TS proband that has several members with obsessive-compulsive symptoms, a bleeding disorder, and an unusual sensitivity to heat. The proband, who is affected by all of these traits...

journal_title：Neurology

authors： Lombroso PJ,Mack G,Scahill L,King RA,Leckman JF

更新日期：1991-12-01 00:00:00

abstract：OBJECTIVE:The presence of cranial autonomic symptoms often leads to a misdiagnosis of "sinus headache" in adult migraineurs, leading to unnecessary treatments and delaying appropriate migraine therapy. In this study, we examined the frequency of cranial autonomic symptoms in pediatric/adolescent patients with migraine....

journal_title：Neurology

authors： Gelfand AA,Reider AC,Goadsby PJ

更新日期：2013-07-30 00:00:00

abstract：:Four patients with disabling action tremor in the setting of MS were treated with isoniazid (800 to 1200 mg per day). All patients showed significant improvement of the tremor, allowing more functional use of their extremities. To the best of our knowledge, this is the only medical treatment for this type of tremor. ...

journal_title：Neurology

authors： Sabra AF,Hallett M,Sudarsky L,Mullally W

更新日期：1982-08-01 00:00:00