Cardiac electrical instability in newly diagnosed/chronic epilepsy tracked by Holter and ECG patch.

abstract：:Children with epilepsy have more behavioral and cognitive problems than children with other chronic illnesses and children in the general population. Risk factors are multiple, probably involving a combination of neurological, seizure, family, and child variables. Problems with attention and symptoms of depression occ...

journal_title：Neurology

authors： Dunn DW,Austin JK

更新日期：1999-01-01 00:00:00

abstract：:We investigated the heterogeneity of serum antibodies to acetylcholine receptor (AChR) by competition with nine antihuman monoclonal antibodies in a cross-sectional study of 36 patients with myasthenia gravis (MG), and in three who showed clinical improvement associated with decrease in total anti-AChR following immun...

journal_title：Neurology

authors： Whiting PJ,Vincent A,Newsom-Davis J

更新日期：1986-05-01 00:00:00

abstract：:We studied the efficacy of divalproex sodium in patients with complex partial seizures taking concomitant carbamazepine or phenytoin as monotherapy. Patients were selected because of inadequate seizure control by current therapy. The primary efficacy measure was median reduction of seizure frequency during add-on trea...

journal_title：Neurology

authors： Willmore LJ,Shu V,Wallin B

更新日期：1996-01-01 00:00:00

abstract：:IgM anti-GM1 antibodies occur with increased frequency in the serum of patients with multifocal motor neuropathy (MMN). We tested the ability of serum IgM from patients with MMN to bind to GM1 ganglioside covalently bound to secondary amino groups on ELISA plates (Co-GM1). The Co-GM1 technique detected high titer (> 1...

journal_title：Neurology

authors： Pestronk A,Choksi R

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVE:This study assessed the tissue integrity of major cervical cord tracts by using diffusion tensor imaging (DTI) to determine the relationship with specific clinical functions carried by those tracts. METHODS:This was a cross-sectional study of 37 patients with multiple sclerosis or neuromyelitis optica with r...

journal_title：Neurology

authors： Naismith RT,Xu J,Klawiter EC,Lancia S,Tutlam NT,Wagner JM,Qian P,Trinkaus K,Song SK,Cross AH

更新日期：2013-06-11 00:00:00

abstract：OBJECTIVE:To identify the metabolic signature of the various levels of cognitive deficits in amyotrophic lateral sclerosis (ALS) using 18F-2-fluoro-2-deoxy-d-glucose-PET (18F-FDG-PET). METHODS:A total of 170 ALS cases consecutively enrolled at the ALS Center of Turin underwent brain 18F-FDG-PET and were classified as ...

journal_title：Neurology

authors： Canosa A,Pagani M,Cistaro A,Montuschi A,Iazzolino B,Fania P,Cammarosano S,Ilardi A,Moglia C,Calvo A,Chiò A

更新日期：2016-01-05 00:00:00

abstract：OBJECTIVE:To characterize a large family with X-linked Charcot-Marie-Tooth (CMT) neuropathy without mutations in the gap junction protein B1 (GJB1) gene, which has an unusual phenotype that is different in some aspects from classic CMTX1. METHODS:We tested CMT families consistent with X-linked inheritance for GJB1 mut...

journal_title：Neurology

authors： Huttner IG,Kennerson ML,Reddel SW,Radovanovic D,Nicholson GA

更新日期：2006-12-12 00:00:00

abstract：OBJECTIVES:1) To reassess the prevalence of migraine in the United States; 2) to assess patterns of migraine treatment in the population; and 3) to contrast current patterns of preventive treatment use with recommendations for use from an expert headache panel. METHODS:A validated self-administered headache questionna...

journal_title：Neurology

authors： Lipton RB,Bigal ME,Diamond M,Freitag F,Reed ML,Stewart WF,AMPP Advisory Group.

更新日期：2007-01-30 00:00:00

abstract：:Acute global aphasia without hemiparesis has been considered pathognomonic of embolic stroke. During 1 year, we encountered six patients with this syndrome. Two had multiple strokes, probably embolic. One had atrial fibrillation; at autopsy, there were metastases as well as multiple infarcts in the left hemisphere. On...

journal_title：Neurology

authors： Legatt AD,Rubin MJ,Kaplan LR,Healton EB,Brust JC

更新日期：1987-02-01 00:00:00

abstract：:Two hundred thirty-nine patients with Bell palsy were randomly distributed into prednisone-treated and control groups. Patients were followed until complete recovery or for 1 year. In the steroid-treated and control groups, respectively, incomplete recovery of facial strength occurred in 12 percent and 20 percent; mot...

journal_title：Neurology

authors： Wolf SM,Wagner JH,Davidson S,Forsythe A

更新日期：1978-02-01 00:00:00

abstract：:In thymomas associated with myasthenia gravis (MG), the authors found that perivascular infiltrates of memory lymphocytes and mature dendritic cells (DCs) were more frequent in patients with early improvement after thymectomy than in patients without response to thymectomy. Although these findings may be limited to pa...

journal_title：Neurology

authors： Nagane Y,Utsugisawa K,Akutsu H,Sato Y,Terayama Y

更新日期：2005-09-13 00:00:00

abstract：OBJECTIVE:To track cognitive and language changes over time in patients with logopenic (lv-PPA) and semantic (sv-PPA) variants of primary progressive aphasia (PPA). METHODS:Thirteen consecutive patients with lv-PPA and 11 patients with sv-PPA underwent yearly evaluation for a mean of 3 years. Nineteen patients (11 lv-...

journal_title：Neurology

authors： Leyton CE,Hsieh S,Mioshi E,Hodges JR

更新日期：2013-03-05 00:00:00

abstract：:The incidence of contrast-induced nephropathy was examined in 1,075 patients receiving routine CT angiography and CT perfusion brain imaging at a single institution. Fifty-two patients had a creatinine rise of > or =0.5 mg/dL. In four patients (0.37%), the administration of IV contrast medium possibly contributed to r...

journal_title：Neurology

authors： Josephson SA,Dillon WP,Smith WS

更新日期：2005-05-24 00:00:00

abstract：BACKGROUND:Charcot Marie Tooth type 1a (CMT1a) is a primarily demyelinating neuropathy, characterized by slowly progressive muscle weakness, atrophy, and sensory loss, and is most pronounced in both feet and hands. There is increasing evidence that muscle weakness is determined by motor axonal dysfunction. OBJECTIVE:T...

journal_title：Neurology

authors： Videler AJ,van Dijk JP,Beelen A,de Visser M,Nollet F,van Schaik IN

更新日期：2008-10-14 00:00:00

abstract：:Four prolonged episodes of partial complex status epilepticus were observed in a teenaged girl. During each there was an "ictal" phase, in which her mental state frequently fluctuated between mildly clouded consciousness and almost total unresponsiveness; once, she was also blind during this phase of impaired consciou...

journal_title：Neurology

authors： Engel J Jr,Ludwig BI,Fetell M

更新日期：1978-09-01 00:00:00

abstract：OBJECTIVE:To compare neurofilament light (NfL) and tau as blood-based biomarkers for acute sports-related concussion (SRC) and determine whether their concentrations at different time points after the injury are associated with prolonged time to return to play (RTP). METHODS:A total of 288 professional hockey players ...

journal_title：Neurology

authors： Shahim P,Tegner Y,Marklund N,Blennow K,Zetterberg H

更新日期：2018-05-15 00:00:00

abstract：OBJECTIVE:To evaluate the effects of sleep on partial seizures arising from various brain regions. METHODS:The authors prospectively studied 133 patients with localization-related epilepsy undergoing video-EEG monitoring over a 2-year period. Seizure type, site of onset, sleep/wake state at onset, duration, and epilep...

journal_title：Neurology

authors： Herman ST,Walczak TS,Bazil CW

更新日期：2001-06-12 00:00:00

abstract：OBJECTIVE:To correlate muscle biopsy findings with prebiopsy and postbiopsy clinical course and response to therapy in polymyositis (PM) and sporadic inclusion body myositis (IBM). BACKGROUND:Existence of pure PM has recently been questioned; subsequently, the definition and criteria for diagnosing PM were debated. M...

journal_title：Neurology

authors： Chahin N,Engel AG

更新日期：2008-02-05 00:00:00

abstract：PURPOSE:To understand the role of the angiopoietin-like 6 gene (ANGPTL6) in intracranial aneurysms (IAs), we investigated its role in a large cohort of familial IAs. METHODS:Individuals with family history of IA were recruited to the Genetic and Observational Subarachnoid Haemorrhage (GOSH) study. The ANGPTL6 gene was...

journal_title：Neurology

authors： Hostettler IC,O'Callaghan B,Bugiardini E,O'Connor E,Vandrovcova J,Davagnanam I,Alg V,Bonner S,Walsh D,Bulters D,Kitchen N,Brown MM,Grieve J,Werring DJ,Houlden H,Genetics and Observational Subarachnoid Haemorrhage (GOSH) Stu

更新日期：2020-10-26 00:00:00

abstract：BACKGROUND:Campylobacter jejuni enteritis is the predominant bacterial infection preceding Guillain-Barré syndrome (GBS), an acute postinfectious immune-mediated polyradiculoneuropathy. The purpose of this study was to define the clinical phenotype of GBS and the relation with preceding C jejuni infections in Banglades...

journal_title：Neurology

authors： Islam Z,Jacobs BC,van Belkum A,Mohammad QD,Islam MB,Herbrink P,Diorditsa S,Luby SP,Talukder KA,Endtz HP

更新日期：2010-02-16 00:00:00

abstract：OBJECTIVE:3-Methylglutaconic aciduria type I is a rare inborn error of leucine catabolism. It is thought to present in childhood with nonspecific symptoms; it was even speculated to be a nondisease. The natural course of disease is unknown. METHODS:This is a study on 10 patients with 3-methylglutaconic aciduria type I...

journal_title：Neurology

authors： Wortmann SB,Kremer BH,Graham A,Willemsen MA,Loupatty FJ,Hogg SL,Engelke UF,Kluijtmans LA,Wanders RJ,Illsinger S,Wilcken B,Cruysberg JR,Das AM,Morava E,Wevers RA

更新日期：2010-09-21 00:00:00

abstract：:Patients, clinicians, and hospitals have undergone monumental changes during the coronavirus disease 2019 (COVID-19) pandemic. This crisis has forced us to consider the obligations that we neurologists have to our individual patients as well as the greater community. By returning to our fundamental understanding of th...

journal_title：Neurology

authors： Rubin MA,Bonnie RJ,Epstein L,Hemphill C,Kirschen M,Lewis A,Suarez JI,Ethics, Law, and Humanities Committee, a joint committee of the American Academy of Neurology, American Neurological Association, and Child Neurology Society; in collabor

更新日期：2020-07-28 00:00:00

abstract：BACKGROUND:An inverse association between cigarette smoking and the risk of idiopathic PD has been found in many epidemiologic studies. The therapeutic and possible neuroprotective effects of nicotine formulations on parkinsonian symptoms are controversial. METHODS:In a 12-week, randomized, double-blind, placebo-contr...

journal_title：Neurology

authors： Vieregge A,Sieberer M,Jacobs H,Hagenah JM,Vieregge P

更新日期：2001-09-25 00:00:00

abstract：:Prompted by the observation that a fellow medical student sneezed at about the same time in class every morning, we recorded the time of each of the 118 sneezes she made on 69 days over a 6.5-month period. Analysis of the sneeze times with the goodness-of-fit test revealed a highly nonuniform distribution (p < 0.0001)...

journal_title：Neurology

authors： Grant AC,Roter EP

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that patients with multiple sclerosis (MS) with intereye asymmetry on low contrast letter acuity, and thickness of the retinal nerve fiber layer (RNFL), would exhibit corresponding changes in cortical timing and amplitude responses on pattern reversal multifocal visual evoked potentials...

journal_title：Neurology

authors： Frohman AR,Schnurman Z,Conger A,Conger D,Beh S,Greenberg B,Sutter E,Calabresi PA,Balcer LJ,Frohman TC,Frohman EM

更新日期：2012-08-21 00:00:00

abstract：OBJECTIVE:To evaluate the safety and efficacy of l-serine in humans with hereditary sensory autonomic neuropathy type I (HSAN1). METHODS:In this randomized, placebo-controlled, parallel-group trial with open-label extension, patients aged 18-70 years with symptomatic HSAN1 were randomized to l-serine (400 mg/kg/day) o...

journal_title：Neurology

authors： Fridman V,Suriyanarayanan S,Novak P,David W,Macklin EA,McKenna-Yasek D,Walsh K,Aziz-Bose R,Oaklander AL,Brown R,Hornemann T,Eichler F

更新日期：2019-01-22 00:00:00

abstract：BACKGROUND:Periodic paralyses and paramyotonia congenita are rare disorders causing disabling weakness and myotonia. Mutations in sodium, calcium, and potassium channels have been recognized as causing disease. OBJECTIVE:To analyze the clinical phenotype of patients with and without discernible genotype and to identif...

journal_title：Neurology

authors： Miller TM,Dias da Silva MR,Miller HA,Kwiecinski H,Mendell JR,Tawil R,McManis P,Griggs RC,Angelini C,Servidei S,Petajan J,Dalakas MC,Ranum LP,Fu YH,Ptácek LJ

更新日期：2004-11-09 00:00:00

abstract：:Among 50 patients with phenytoin intoxication, 14 had seizures during the episode. Seizures in 9 of these 14 patients probably resulted from poor seizure control despite high phenytoin levels, but in 5 cases, attacks were attributed to phenytoin toxicity. The only factor that seemed to correlate with seizures was a se...

journal_title：Neurology

authors： Stilman N,Masdeu JC

更新日期：1985-12-01 00:00:00

abstract：:Increased urinary levels of the polyamines, putrescine, spermidine, and spermine are present in Duchenne muscular dystrophy (DMD) patients. Alterations in excretion are detectable when based on nanomoles per milligram creatinine, micromoles per 24-hour urine collection, or nanomoles per kilogram body weight per 24-hou...

journal_title：Neurology

authors： Russell DH,Stern LZ

更新日期：1981-01-01 00:00:00

abstract：OBJECTIVE:To investigate the temporal relationship between inflammation and cerebral atrophy in a longitudinal study of 19 patients with relapsing-remitting multiple sclerosis (RRMS) using serial monthly contrast enhanced MRI examinations and monthly measurements of brain fractional volume (BFV) for an average of 4 (ra...

journal_title：Neurology

authors： Richert ND,Howard T,Frank JA,Stone R,Ostuni J,Ohayon J,Bash C,McFarland HF

更新日期：2006-02-28 00:00:00