Discontinuation of anticonvulsant therapy in children with partial epilepsy.

abstract：:Acute in-stent thrombosis is a well-known complication of carotid angioplasty and stenting (CAS) and often due to resistance to or inadequate treatment with platelet-inhibiting agents. The authors report three cases of a delayed in-stent thrombosis after more than a week but less than 3 months after CAS. In all cases,...

journal_title：Neurology

authors： Buhk JH,Wellmer A,Knauth M

更新日期：2006-05-23 00:00:00

abstract：:Tolcapone is a potent, reversible inhibitor of catechol O-methyltransferase (COMT) intended for use as an adjunct to levodopa therapy for Parkinson's disease (PD). Findings from the first pharmacokinetics/pharmacodynamics and tolerability studies of tolcapone in volunteers are reviewed. Following linear and dose-propo...

journal_title：Neurology

authors： Jorga KM

更新日期：1998-05-01 00:00:00

abstract：:Hypnic headache has been described in several case reports since 1981 and is regarded as an idiopathic headache disorder. In this review of 71 cases in the literature, the clinical features, neurophysiologic including polysomnographic findings, and treatment procedures are analyzed and the pathophysiology of this cond...

journal_title：Neurology

authors： Evers S,Goadsby PJ

更新日期：2003-03-25 00:00:00

abstract：OBJECTIVES:To test the hypothesis that neuropsychiatric symptomatology is predictive of the success of seizure control in patients newly treated with antiepileptic drugs (AEDs), and that this predictive value adds to that provided by other clinical, imaging, and genomic factors in a multivariate model. METHODS:One hun...

journal_title：Neurology

authors： Petrovski S,Szoeke CE,Jones NC,Salzberg MR,Sheffield LJ,Huggins RM,O'Brien TJ

更新日期：2010-09-14 00:00:00

abstract：:Proximal myotonic myopathy (PROMM) is an autosomal dominantly inherited multisystemic disorder characterized by myotonia, proximal muscle weakness, and cataracts. This disorder is not linked to the gene locus of myotonic dystrophy (DM). We describe three new families with PROMM. In all patients, CTG repeats of the DM ...

journal_title：Neurology

authors： Hund E,Jansen O,Koch MC,Ricker K,Fogel W,Niedermaier N,Otto M,Kuhn E,Meinck HM

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:To describe and analyze etiologies, clinical presentations, therapeutic management, and outcomes of patients with acute encephalitis and identify outcome predictors. METHODS:We conducted a retrospective review of patients diagnosed with acute encephalitis at Mayo Clinic Rochester between January 2000 and Dec...

journal_title：Neurology

authors： Singh TD,Fugate JE,Rabinstein AA

更新日期：2015-01-27 00:00:00

abstract：OBJECTIVE:The current literature provides discrepant results regarding preoperative sociodemographic and clinical factors, and no information about preoperative cerebral metabolic patterns associated with apathy after subthalamic nucleus deep brain stimulation (STN-DBS) in Parkinson disease. METHODS:To resolve this is...

journal_title：Neurology

authors： Robert GH,Le Jeune F,Lozachmeur C,Drapier S,Dondaine T,Péron J,Houvenaghel JF,Travers D,Sauleau P,Millet B,Vérin M,Drapier D

更新日期：2014-10-28 00:00:00

abstract：OBJECTIVE:To investigate the role of intragenic deletions of ALDH7A1 in patients with clinical and biochemical evidence of pyridoxine-dependent epilepsy but only a single identifiable mutation in ALDH7A1. METHODS:We designed a custom oligonucleotide array with high-density probe coverage across the ALDH7A1 gene. We pe...

journal_title：Neurology

authors： Mefford HC,Zemel M,Geraghty E,Cook J,Clayton PT,Paul K,Plecko B,Mills PB,Nordli DR Jr,Gospe SM Jr

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:To investigate the association between discordant β-amyloid (Aβ) PET and CSF biomarkers at baseline and the emergence of tau pathology 5 years later. METHODS:We included 730 Alzheimer's Disease Neuroimaging Initiative (ADNI) participants without dementia (282 cognitively normal, 448 mild cognitive impairment...

journal_title：Neurology

authors： Reimand J,Collij L,Scheltens P,Bouwman F,Ossenkoppele R,Alzheimer's Disease Neuroimaging Initiative.

更新日期：2020-11-10 00:00:00

abstract：OBJECTIVE:To investigate the feasibility and clinical utility of using passive electrocorticography (ECoG) for online spatial-temporal functional mapping (STFM) of language cortex in patients being monitored for epilepsy surgery. METHODS:We developed and tested an online system that exploits ECoG's temporal resolution...

journal_title：Neurology

authors： Wang Y,Fifer MS,Flinker A,Korzeniewska A,Cervenka MC,Anderson WS,Boatman-Reich DF,Crone NE

更新日期：2016-03-29 00:00:00

abstract：:The present study sought to evaluate the validity and generality of the Mini-Mental State Examination (MMSE) and its subsection scores. We gave the MMSE and other neuropsychological tests to 51 patients with probable Alzheimer's disease. On the basis of correlational and factor analyses, overall performance on the MMS...

journal_title：Neurology

authors： Giordani B,Boivin MJ,Hall AL,Foster NL,Lehtinen SJ,Bluemlein LA,Berent S

更新日期：1990-12-01 00:00:00

abstract：PURPOSE:To assess the extent of demyelination in cervical spondylotic myelopathy (CSM) using myelin water imaging (MWI) and electrophysiologic techniques. METHODS:Somatosensory evoked potentials (SSEPs) and MWI were acquired in 14 patients with CSM and 18 age-matched healthy controls. MWI was performed on a 3.0T whole...

journal_title：Neurology

authors： Liu H,MacMillian EL,Jutzeler CR,Ljungberg E,MacKay AL,Kolind SH,Mädler B,Li DKB,Dvorak MF,Curt A,Laule C,Kramer JLK

更新日期：2017-08-08 00:00:00

abstract：:Intracranial hypertension in the absence of an intracranial mass lesion or hydrocephalus can be caused by an alteration of one or more of the four determinants of cerebrospinal fluid (CSF) pressure: (1) intrasagittal sinus pressure, (2) resistance of arachnoid villi to the egress of CSF, (3) rate of production of CSF,...

journal_title：Neurology

authors： Donaldson JO

更新日期：1981-07-01 00:00:00

abstract：:The authors performed serial transcranial Doppler (TCD) and carbon dioxide reactivity (CO2R) testing in 20 aneurysmal subarachnoid hemorrhage patients to determine whether impaired cerebrovascular reactivity was associated with symptomatic vasospasm. Symptomatic vasospasm occurred in 9 of 14 patients with abnormal CO2...

journal_title：Neurology

authors： Frontera JA,Rundek T,Schmidt JM,Claassen J,Parra A,Wartenberg KE,Temes RE,Mayer SA,Mohr JP,Marshall RS

更新日期：2006-03-14 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness of yoga as an adjuvant to conventional medical management on clinical outcomes in patients with migraine. METHODS:CONTAIN was a prospective, randomized, open-label superiority trial with blinded endpoint assessment carried out at a single tertiary care academic hospital in New D...

journal_title：Neurology

authors： Kumar A,Bhatia R,Sharma G,Dhanlika D,Vishnubhatla S,Singh RK,Dash D,Tripathi M,Srivastava MVP

更新日期：2020-05-26 00:00:00

abstract：:Four patients with presumed Tolosa-Hunt syndrome ultimately proved to have a parasellar tumor. All four had manifestations of a cavernous sinus syndrome, normal radiologic and medical investigations, and response to steroid therapy. The Tolosa-Hunt syndrome is a diagnosis of exclusion; many other lesions can simulate ...

journal_title：Neurology

authors： Spector RH,Fiandaca MS

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:Epidemiologic and laboratory studies suggest that nonsteroidal antiinflammatory drugs (NSAIDs) reduce risk of Alzheimer disease (AD). We therefore investigated the association between use of NSAIDs, aspirin, and the non-NSAID analgesic acetaminophen with incidence of dementia and AD. METHODS:Participants in...

journal_title：Neurology

authors： Szekely CA,Breitner JC,Fitzpatrick AL,Rea TD,Psaty BM,Kuller LH,Zandi PP

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:To assess the inpatient hospitalization burden and costs of patients with autoimmune encephalitis (AE) at a tertiary care institution. METHODS:Adult inpatients with AE were identified retrospectively from July 1, 2005, to June 30, 2015. Demographic and clinical data were collected and analyzed. Billing data ...

journal_title：Neurology

authors： Cohen J,Sotoca J,Gandhi S,Yeshokumar AK,Gordon-Lipkin E,Geocadin RG,Frick KD,Probasco JC,Venkatesan A

更新日期：2019-02-26 00:00:00

abstract：:Because Hughlings Jackson directed that his personal documents be destroyed upon his death, none of his own clinical records are known. However, we have discovered several pages of notes in the Royal London Hospital Archive written in 1893 by Jackson to his House Physician at Queen Square concerning his proposals for ...

journal_title：Neurology

authors： Swash M,Evans J

更新日期：2006-08-22 00:00:00

abstract：OBJECTIVE:To determine the usefulness of the 14-3-3 test in patients with dementia of various causes. BACKGROUND:Recent reports have suggested that the detection of the 14-3-3 protein in the CSF of patients with Creutzfeldt--Jakob disease is a highly sensitive and specific marker of the disease that might be used as a...

journal_title：Neurology

authors： Burkhard PR,Sanchez JC,Landis T,Hochstrasser DF

更新日期：2001-06-12 00:00:00

abstract：:We measured the concentrations of the monoamines, their precursors, and their metabolites, and the activity of choline acetyltransferase (ChAT) in basal ganglia and cortical regions of postmortem brains from cases with histologically verified pure Alzheimer's disease (AD), AD with diffusely distributed Lewy bodies (Le...

journal_title：Neurology

authors： Langlais PJ,Thal L,Hansen L,Galasko D,Alford M,Masliah E

更新日期：1993-10-01 00:00:00

abstract：:Five women are presented with a subacute pure pancerebellar syndrome of ataxia and dysarthria to emphasize that this illness may occur without anti-Purkinje-cell or anti-Yo antibodies, or associated systemic cancer. The syndrome evolved over weeks or less and stabilized in four of the patients. Three had had a precedi...

journal_title：Neurology

authors： Ropper AH

更新日期：1993-08-01 00:00:00

abstract：:We enrolled 116 patients in a multicenter, randomized, double-blind controlled trial of an 8-week course of 11 plasma exchange (PE) treatments in exacerbations of MS. The control group received sham PE, and both groups received identical treatment with IM ACTH and oral cyclophosphamide. Serum IgG decreased in the PE a...

journal_title：Neurology

authors： Weiner HL,Dau PC,Khatri BO,Petajan JH,Birnbaum G,McQuillen MP,Fosburg MT,Feldstein M,Orav EJ

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND:The prognostic value of the biochemical changes seen with proton MR spectroscopy (1H MRS) in ischemic stroke was examined. Acute diffusion-weighted imaging (DWI) was used to identify regions of ischemia for 1H MRS voxel localization. METHODS:Nineteen patients had 36 1H MRS studies, 13 patients acutely (mean...

journal_title：Neurology

authors： Parsons MW,Li T,Barber PA,Yang Q,Darby DG,Desmond PM,Gerraty RP,Tress BM,Davis SM

更新日期：2000-08-22 00:00:00

abstract：OBJECTIVE:To assess the frequency of this finding in patients with minor stroke and TIAs compared to those with stroke mimics and to evaluate the level of agreement between examiners to detect an upgoing thumb sign. METHODS:We previously reported an upgoing thumb sign as a subtle clinical finding in patients with tran...

journal_title：Neurology

authors： Hachinski V,Alsubaie R,Azarpazhooh MR

更新日期：2017-07-25 00:00:00

abstract：:All but 6% of the subjects with relapsing remitting MS who were randomly assigned to receive glatiramer acetate or placebo for the 9-month controlled phase of the European/Canadian MRI trial entered an open-label extension with quarterly clinical and MRI evaluations for another 9 months. There was a 54% reduction in t...

journal_title：Neurology

authors： Wolinsky JS,Comi G,Filippi M,Ladkani D,Kadosh S,Shifroni G,European\/Canadian Glatiramer Acetate Study Group.

更新日期：2002-10-22 00:00:00

abstract：:A kindred is described with a dominantly inherited "pure" cerebellar ataxia in which the currently known spinocerebellar ataxias have been excluded. In the eight subjects studied, a notable clinical feature is slow progression, with the three least affected having only a mild degree of gait ataxia after three or more ...

journal_title：Neurology

authors： Storey E,Gardner RJ,Knight MA,Kennerson ML,Tuck RR,Forrest SM,Nicholson GA

更新日期：2001-11-27 00:00:00

abstract：:We tested serum specimens from patients with HAM/TSP and asymptomatic HTLV-I carriers from endemic areas of Japan, Jamaica, Colombia, and Chile for neutralizing antibodies against HTLV-I. The data suggest a trend for neutralizing activity to be found more frequently in the sera from HAM/TSP patients than in sera from ...

journal_title：Neurology

authors： Minagawa H,Yoshida T,Itoyama Y,Mora CA,Albert P,Mori R

更新日期：1992-11-01 00:00:00

abstract：:Cisternography and ventriculography were performed in five normal anesthetized dogs to study the dynamics of tracer dispersal. Indium 111-diethylenetriaminepentaacetic acid was injected into lateral ventricles, cisterna magna, thoracic subarachnoid space, and lumbar sac. The patterns of dispersal from each injection s...

journal_title：Neurology

authors： Schossberger PF,Touya JJ

更新日期：1976-03-01 00:00:00

abstract：:Generic substitution is practiced widely in both hospital and community settings. There have been several reports of reduced serum concentrations and seizure exacerbation following generic substitution of Tegretol. We describe the first 2 cases of carbamazepine toxicity resulting from the substitution of Tegretol with...

journal_title：Neurology

authors： Gilman JT,Alvarez LA,Duchowny M

更新日期：1993-12-01 00:00:00