An expression for backscatter factors for orthovoltage x-rays.

abstract：:In CT imaging, a variety of applications exist which are strongly SNR limited. However, in some cases redundant data of the same body region provide additional quanta. Examples in dual energy CT, the spatial resolution has to be compromised to provide good SNR for material decomposition. However, the respective spectr...

journal_title：Physics in medicine and biology

authors： Bruder H,Raupach R,Sunnegardh J,Allmendinger T,Klotz E,Stierstorfer K,Flohr T

更新日期：2015-11-07 00:00:00

abstract：:The purpose of this study is to evaluate a new method to improve performance of computer-aided detection (CAD) schemes of screening mammograms with two approaches. In the first approach, we developed a new case based CAD scheme using a set of optimally selected global mammographic density, texture, spiculation, and st...

journal_title：Physics in medicine and biology

authors： Tan M,Aghaei F,Wang Y,Zheng B

更新日期：2017-01-21 00:00:00

abstract：:Segmentation of liver in abdominal computed tomography (CT) is an important step for radiation therapy planning of hepatocellular carcinoma. Practically, a fully automatic segmentation of liver remains challenging because of low soft tissue contrast between liver and its surrounding organs, and its highly deformable s...

journal_title：Physics in medicine and biology

authors： Qin W,Wu J,Han F,Yuan Y,Zhao W,Ibragimov B,Gu J,Xing L

更新日期：2018-05-04 00:00:00

abstract：:A complete characterization of spongiosa (bone marrow plus trabecular bone) is required to calculate the absorbed dose to active bone marrow. Due to the complex microanatomy, it is necessary to apply non-conventional imaging methods in nuclear medicine. The aim of this study is validating a phantomless quantification ...

journal_title：Physics in medicine and biology

authors： Salas-Ramirez M,Tran-Gia J,Gbureck U,Kosmala A,Lassmann M

更新日期：2019-10-16 00:00:00

abstract：:In dual energy x-ray absorptiometry (DXA) the photon attenuation is assumed to be similar in soft tissue overlying, adjacent to and inside the measured bone. In the calcaneal dual energy x-ray laser (DXL) technique, this assumption is not needed as attenuation by soft tissues at the local bone site is determined by co...

journal_title：Physics in medicine and biology

authors： Hakulinen MA,Saarakkala S,Töyräs J,Kröger H,Jurvelin JS

更新日期：2003-06-21 00:00:00

abstract：:Single monochromator charge-coupled device (CCD) array spectroradiometers have the advantage of ease of use and speed compared with double grating instruments. Their inherently inferior stray-light rejection, however, can critically affect their accuracy in phototherapy and research-related dosimetry applications. Thi...

journal_title：Physics in medicine and biology

authors： Coleman A,Sarkany R,Walker S

更新日期：2008-09-21 00:00:00

abstract：:Blood and blood products are irradiated with gamma rays to reduce the risk of graft versus host disease (GVHD). A simple technique using electron beams produced by a medical linear accelerator has been studied to evaluate irradiation of blood and blood products. Variations in applied doses for a single field 20 MeV el...

journal_title：Physics in medicine and biology

authors： Butson MJ,Cheung T,Yu PK,Stokes MJ

更新日期：2000-11-01 00:00:00

abstract：:In this paper, we investigate an off-line strategy to incorporate inter-fraction organ motion in IMRT treatment planning. It was suggested that inverse planning could be based on a probability distribution of patient geometries instead of a single snap shot. However, this concept is connected to two intrinsic problems...

journal_title：Physics in medicine and biology

authors： Unkelbach J,Oelfke U

更新日期：2004-09-07 00:00:00

abstract：:Microbeam radiation therapy (MRT) is a treatment approach in radiation therapy where the treatment field is spatially fractionated into arrays of a few tens of micrometre wide planar beams of unusually high peak doses separated by low dose regions of several hundred micrometre width. In preclinical studies, this treat...

journal_title：Physics in medicine and biology

authors： Debus C,Oelfke U,Bartzsch S

更新日期：2017-10-19 00:00:00

abstract：:The incorporation of accurately aligned anatomical information as a prior to guide reconstruction and noise regularization in positron emission tomography (PET) has been suggested in many previous studies. However, the advantages of this approach can only be realized if the exact lesion outline is also available. In p...

journal_title：Physics in medicine and biology

authors： Chan C,Fulton R,Feng DD,Meikle S

更新日期：2009-12-21 00:00:00

abstract：:Managing uncertainty is a major challenge in radiation therapy treatment planning, including uncertainty induced by intrafraction motion, which is particularly important for tumours in the thorax and abdomen. Common methods to account for motion are to introduce a margin or to convolve the static dose distribution wit...

journal_title：Physics in medicine and biology

authors： Chan TC,Bortfeld T,Tsitsiklis JN

更新日期：2006-05-21 00:00:00

abstract：:At low and intermediate frequencies, the strength of the induced electric field is used as dosimetric quantity for human protection in the International Commission on Non-Ionizing Radiation Protection (ICNIRP) guidelines. To compute the induced electric field, numerical methods based on anatomically realistic voxel mo...

journal_title：Physics in medicine and biology

authors： Soldati M,Laakso I

更新日期：2020-01-10 00:00:00

abstract：:Optimization-based algorithms for image reconstruction in multispectral (or photon-counting) computed tomography (MCT) remains a topic of active research. The challenge of optimization-based image reconstruction in MCT stems from the inherently non-linear data model that can lead to a non-convex optimization program f...

journal_title：Physics in medicine and biology

authors： Chen B,Zhang Z,Sidky EY,Xia D,Pan X

更新日期：2017-11-02 00:00:00

abstract：:Geometric and penetration responses of a multihole focusing collimator to a point source have been determined using a digital computer and a ray tracing technique. Results are presented as point and line spread functions for collimated rays and penetrating rays, and as plane sensitivities and modulation transfer funct...

journal_title：Physics in medicine and biology

authors： Jahns MJ

更新日期：1981-01-01 00:00:00

abstract：:Under various clinical situations, it is desirable to modify the original treatment plan to better suit the clinical goals. In this work, a method to help physicians modify treatment plans based on their clinical preferences is proposed. The method uses a weighted quadratic dose objective function. The commonly used o...

journal_title：Physics in medicine and biology

authors： Wu C,Olivera GH,Jeraj R,Keller H,Mackie TR

更新日期：2003-08-07 00:00:00

abstract：:In recent years there has been a large amount of research into the potential use of radiation sensitive gels for three-dimensional verification of clinical radiotherapy doses. In this paper we report the use of a MAGIC gel dosimeter (Fong et al 2001 Phys. Med. Biol. 46 3105) for the verification of a specific patient'...

journal_title：Physics in medicine and biology

authors： Trapp JV,Partridge M,Hansen VN,Childs P,Bedford J,Warrington AP,Leach MO,Webb S

更新日期：2004-05-07 00:00:00

abstract：:The objective of this work is to test analytical models to calculate the luminescence efficiency of Al(2)O(3):C optically stimulated luminescence detectors (OSLDs) exposed to heavy charged particles with energies relevant to space dosimetry and particle therapy. We used the track structure model to obtain an analytica...

journal_title：Physics in medicine and biology

authors： Sawakuchi GO,Yukihara EG

更新日期：2012-01-21 00:00:00

abstract：:The University of Washington (UW) Clinical Neutron Therapy System (CNTS) has been used to treat over 3300 patients. Treatment planning for these patients is currently performed using an MV x-ray model in Pinnacle® adapted to fit measurements of fast neutron output factors, wedge factors, depth-dose and lateral profile...

journal_title：Physics in medicine and biology

authors： Moffitt GB,Wootton LS,Hårdemark B,Sandison GA,Laramore GE,Parvathaneni U,Stewart RD

更新日期：2020-08-31 00:00:00

abstract：:An algorithm is described for three-dimensional whole-body (3DWB) image reconstruction in positron emission tomography. For whole-body applications, improvements to the popular fixed-axial-acceptance-angle technique are achieved by combining axially adjacent projection data available with a long-axis data set. Time-co...

journal_title：Physics in medicine and biology

authors： Cutler PD,Xu M

更新日期：1996-08-01 00:00:00

abstract：:In carbon-ion radiotherapy, single-beam delivery each day in alternate directions has been common practice for efficient operation, taking advantage of the Bragg peak and the relative biological effectiveness (RBE) for uniform dose conformation to a tumor. Treatments are usually fractionated and treatment plans are ev...

journal_title：Physics in medicine and biology

authors： Kanematsu N,Inaniwa T

更新日期：2017-02-07 00:00:00

abstract：:Focused ultrasound and microbubbles have been extensively used to generate therapeutic bioeffects. Despite encouraging in vivo results, there remains poor control of the magnitude and spatial distribution of these bioeffects due to the limited ability of conventional pulse shapes and sequences to control cavitation dy...

journal_title：Physics in medicine and biology

authors： Pouliopoulos AN,Bonaccorsi S,Choi JJ

更新日期：2014-11-21 00:00:00

abstract：:A new thin-target method (patent pending) is described for portal imaging with low-energy (tens of keV) photons from a medical linear accelerator operating in a special mode. Low-energy photons are usually produced in the accelerator target, but are absorbed by the target and flattening filter, both made of medium- or...

journal_title：Physics in medicine and biology

authors： Tsechanski A,Bielajew AF,Faermann S,Krutman Y

更新日期：1998-08-01 00:00:00

abstract：:The silicon photomultiplier (Si-PM) is a promising photo-detector for PET for use in magnetic resonance imaging (MRI) systems because it has high gain and is insensitive to static magnetic fields. Recently we developed a Si-PM-based depth-of-interaction PET system for small animals and performed simultaneous measureme...

journal_title：Physics in medicine and biology

authors： Yamamoto S,Watabe T,Watabe H,Aoki M,Sugiyama E,Imaizumi M,Kanai Y,Shimosegawa E,Hatazawa J

更新日期：2012-01-21 00:00:00

abstract：:This work is dedicated to the reduction of reconstruction artefacts due to motion occurring during the acquisition of computerized tomographic projections. This problem has to be solved when imaging moving organs such as the lungs or the heart. The proposed method belongs to the class of motion compensation algorithms...

journal_title：Physics in medicine and biology

authors： Roux S,Desbat L,Koenig A,Grangeat P

更新日期：2004-06-07 00:00:00

abstract：:Thermal therapy is an experimental treatment to destroy solid tumours by heating them to temperatures ranging from 55 degrees C to 90 degrees C, inducing thermal coagulation and necrosis of the tumour. We are investigating the feasibility of interstitial microwave thermal therapy as a salvage treatment for prostate ca...

journal_title：Physics in medicine and biology

authors： McCann C,Kumaradas JC,Gertner MR,Davidson SR,Dolan AM,Sherar MD

更新日期：2003-04-21 00:00:00

abstract：:Despite over ten years of in vitro investigations of ultrasound contrast agents, the level of understanding of their behaviour in ultrasound fields is limited. Several problems associated with these investigations, particular to the nature of contrast agents, are discussed. Using a commercial scanner the RF normalized...

journal_title：Physics in medicine and biology

authors： Sboros V,Ramnarine KV,Moran CM,Pye SD,McDicken WN

更新日期：2002-12-07 00:00:00

abstract：:The basic principles of x-ray image formation in radiology have remained essentially unchanged since Röntgen first discovered x-rays over a hundred years ago. The conventional approach relies on x-ray attenuation as the sole source of contrast and draws exclusively on ray or geometrical optics to describe and interpre...

journal_title：Physics in medicine and biology

authors： Bech M,Bunk O,Donath T,Feidenhans'l R,David C,Pfeiffer F

更新日期：2010-09-21 00:00:00

abstract：:MRI-guided prostate biopsy in conventional closed-bore scanners requires transferring the patient outside the bore during needle insertion due to the constrained in-bore space, causing a safety hazard and limiting image feedback. To address this issue, we present our custom-made in-bore setup and software to support M...

journal_title：Physics in medicine and biology

authors： Tokuda J,Tuncali K,Iordachita I,Song SE,Fedorov A,Oguro S,Lasso A,Fennessy FM,Tempany CM,Hata N

更新日期：2012-09-21 00:00:00

abstract：:In radiotherapy with photon beams, the use of dynamic wedges, which are obtained by the movement of one of the jaws, offers an increasing flexibility relative to the traditional use of metal wedges. But it is a disadvantage for the measurement of absorbed dose distributions, because the absorbed dose at each measureme...

journal_title：Physics in medicine and biology

authors： Storchi P,Woudstra E,Verlinde P,Johansson KA,Samuelsson A

更新日期：1998-06-01 00:00:00

abstract：:We have developed an impedance magnetocardiogram (IMCG) system to detect the change of magnetic field corresponding to changes in blood volume in the heart. A low magnetic field from the electrical activity of the human heart--the so-called magnetocardiogram (MCG)--can be simultaneously detected by using this system. ...

journal_title：Physics in medicine and biology

authors： Kandori A,Miyashita T,Suzuki D,Yokosawa K,Tsukada K

更新日期：2001-02-01 00:00:00