Abstract:
:Blood and blood products are irradiated with gamma rays to reduce the risk of graft versus host disease (GVHD). A simple technique using electron beams produced by a medical linear accelerator has been studied to evaluate irradiation of blood and blood products. Variations in applied doses for a single field 20 MeV electron beam are measured in a phantom study. Doses have been verified with ionization chambers and commercial diode detectors. Results show that the blood product volume can be given a relatively homogeneous dose to within 6% using 20 MeV electrons without the need to rotate the blood bags or the beam entry point. The irradiation process takes approximately 6.5 minutes for 30 Gy applied dose to complete as opposed to 12 minutes for a dual field x-ray field irradiation at our centre. Electron beams can be used to satisfactorily irradiate blood and blood products in a minimal amount of time.
journal_name
Phys Med Bioljournal_title
Physics in medicine and biologyauthors
Butson MJ,Cheung T,Yu PK,Stokes MJdoi
10.1088/0031-9155/45/11/401subject
Has Abstractpub_date
2000-11-01 00:00:00pages
N139-42issue
11eissn
0031-9155issn
1361-6560journal_volume
45pub_type
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