Automated detection of clustered microcalcifications on mammograms: CAD system application to MIAS database.

abstract：:Transcranial direct current stimulation (tDCS) is a neuromodulation scheme where a small current is delivered to the brain via two electrodes attached to the scalp. The electrode design is an important topic, not only as regards efficacy, but also from a safety perspective, as tDCS may be related to skin lesions that ...

journal_title：Physics in medicine and biology

authors： Gomez-Tames J,Sugiyama Y,Laakso I,Tanaka S,Koyama S,Sadato N,Hirata A

更新日期：2016-12-21 00:00:00

abstract：:Photosensitizer fluorescence excited by photodynamic therapy (PDT) treatment light can be used to monitor the in vivo concentration of the photosensitizer and its photobleaching. The temporal integral of the product of in vivo photosensitizer concentration and light fluence is called PDT dose, which is an important do...

journal_title：Physics in medicine and biology

authors： Ong YH,Kim MM,Finlay JC,Dimofte A,Singhal S,Glatstein E,Cengel KA,Zhu TC

更新日期：2017-12-29 00:00:00

abstract：:Monte Carlo (MC) simulations are often at the heart of the testing procedure in biomedical optics. One of the critical points in MC simulations is to define the new photon direction after each scattering event. One of the most popular solutions is to use the Henyey-Greenstein phase function or some linear combinations...

journal_title：Physics in medicine and biology

authors： Binzoni T,Leung TS,Gandjbakhche AH,Rüfenacht D,Delpy DT

更新日期：2006-09-07 00:00:00

abstract：:In recent years there has been a large amount of research into the potential use of radiation sensitive gels for three-dimensional verification of clinical radiotherapy doses. In this paper we report the use of a MAGIC gel dosimeter (Fong et al 2001 Phys. Med. Biol. 46 3105) for the verification of a specific patient'...

journal_title：Physics in medicine and biology

authors： Trapp JV,Partridge M,Hansen VN,Childs P,Bedford J,Warrington AP,Leach MO,Webb S

更新日期：2004-05-07 00:00:00

abstract：:We discuss the use of terahertz time domain spectroscopy for studies of conformational flexibility and conformational change in biomolecules. Protein structural dynamics are vital to biological function with protein flexibility affecting enzymatic reaction rates and sensory transduction cycling times. Conformational m...

journal_title：Physics in medicine and biology

authors： Markelz A,Whitmire S,Hillebrecht J,Birge R

更新日期：2002-11-07 00:00:00

abstract：:Area laser lathing and trephination of donor corneas is used to produce different types of grafts for human transplantation. 193 nm (ArF excimer) laser radiation is used, since this is known to give a non-thermal laser-tissue interaction with a minimal zone of tissue damage. To guarantee the highest degree of flexibil...

journal_title：Physics in medicine and biology

authors： Homolka P,Biowski R,Kaminski S,Barisani T,Husinsky W,Bergmann H,Grabner G

更新日期：1999-05-01 00:00:00

abstract：:The purpose of this work was to use Monte Carlo simulations to verify the accuracy of the dose distributions from a commercial treatment planning optimization system (Corvus, Nomos Corp., Sewickley, PA) for intensity-modulated radiotherapy (IMRT). A Monte Carlo treatment planning system has been implemented clinically...

journal_title：Physics in medicine and biology

authors： Ma CM,Pawlicki T,Jiang SB,Li JS,Deng J,Mok E,Kapur A,Xing L,Ma L,Boyer AL

更新日期：2000-09-01 00:00:00

abstract：:A two-probe technique has been developed to measure 125I in the thyroid. In this technique simultaneous emissions from a source are detected as coincidence events between two probes rather than as a sum peak in a single probe (the sum peak method). The background count rate when counting coincidence events between pro...

journal_title：Physics in medicine and biology

authors： Burns PA,Peggie JR

更新日期：1980-05-01 00:00:00

abstract：:Due to high levels of noise in pixel-wise time-activity curves, the indirect method that generates kinetic parametric images from dynamic positron emission tomography (PET) images often results in poor parametric image quality. We have demonstrated that the quality of parametric images can be improved by denoising dyn...

journal_title：Physics in medicine and biology

authors： Huang HM

更新日期：2020-11-17 00:00:00

abstract：:We give an overview of the role of Physics in Medicine and Biology in the development of tomographic reconstruction algorithms. We focus on imaging modalities involving ionizing radiation, CT, PET and SPECT, and cover a wide spectrum of reconstruction problems, starting with classical 2D tomography in the 1970s up to ...

journal_title：Physics in medicine and biology

authors： Defrise M,Gullberg GT

更新日期：2006-07-07 00:00:00

abstract：:Experimental radiobiological investigations of fast neutron beams involve irradiation of thin cell layers. The irradiation of cells is done either in free air or with a material such as graphite, TE plastic or bone-equivalent plastic covering the cells. This paper discusses the computed dose distributions in LET at sh...

journal_title：Physics in medicine and biology

authors： Bhatia DP,Nagarajan PS

更新日期：1979-09-01 00:00:00

abstract：:This paper extends the kernel method that was proposed previously for dynamic PET reconstruction, to incorporate anatomical side information into the PET reconstruction model. In contrast to existing methods that incorporate anatomical information using a penalized likelihood framework, the proposed method incorporate...

journal_title：Physics in medicine and biology

authors： Hutchcroft W,Wang G,Chen KT,Catana C,Qi J

更新日期：2016-09-21 00:00:00

abstract：:Microbeam radiation therapy (MRT) is a treatment approach in radiation therapy where the treatment field is spatially fractionated into arrays of a few tens of micrometre wide planar beams of unusually high peak doses separated by low dose regions of several hundred micrometre width. In preclinical studies, this treat...

journal_title：Physics in medicine and biology

authors： Debus C,Oelfke U,Bartzsch S

更新日期：2017-10-19 00:00:00

abstract：:Novel x-ray medical imaging sensors, such as photon counting detectors (PCDs) and large area CCD and CMOS cameras can involve irregular and/or sparse sampling of the detector plane. Application of such detectors to CT involves undersampling that is markedly different from the commonly considered case of sparse angular...

journal_title：Physics in medicine and biology

authors： Sisniega A,Zbijewski W,Stayman JW,Xu J,Taguchi K,Fredenberg E,Lundqvist M,Siewerdsen JH

更新日期：2016-01-07 00:00:00

abstract：:The purpose of this work is to develop a validated Geant4 simulation model of a whole-body prototype PET scanner constructed from the four-layer depth-of-interaction detectors developed at the National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Japan. T...

journal_title：Physics in medicine and biology

authors： Ahmed AM,Chacon A,Rutherford H,Akamatsu G,Mohammadi A,Nishikido F,Tashima H,Yoshida E,Yamaya T,Franklin DR,Rosenfeld A,Guatelli S,Safavi-Naeini M

更新日期：2020-12-18 00:00:00

abstract：:An in vivo probe was compared with a gamma camera for the task of detecting radiolabelled tumour models in a water phantom. The probe, which contained a 1 cm diameter NaI(T1) detector, was designed and used by us for surgical staging studies of gynaecological patients. Tumours were spherical sources of different sizes...

journal_title：Physics in medicine and biology

authors： Barber HB,Barrett HH,Woolfenden JM,Myers KJ,Hickernell TS

更新日期：1989-06-01 00:00:00

abstract：:Lung tumors treated in breath-hold are subject to inter- and intra-breath-hold variations, which makes tumor position monitoring during each breath-hold important. A markerless technique is desirable, but limited tumor visibility on kV images makes this challenging. We evaluated if template matching  +  triangulation ...

journal_title：Physics in medicine and biology

authors： Hazelaar C,Dahele M,Mostafavi H,van der Weide L,Slotman B,Verbakel W

更新日期：2018-05-29 00:00:00

abstract：:Ultrasound shock wave therapy is increasingly used for non-invasive surgery. It requires the focusing of very high pressure amplitude in precisely controlled focal spots. In transcostal therapy of the heart or the liver, the high impedance mismatch between the bones and surrounding tissues gives rise to strong aberrat...

journal_title：Physics in medicine and biology

authors： Robin J,Simon A,Arnal B,Tanter M,Pernot M

更新日期：2018-09-06 00:00:00

abstract：:During minimally invasive surgery (MIS) for lung tumor resection, the localization of tumors or nodules relies on visual inspection of the deflated lung on intra-procedural video. For patients with tumors or nodules located deeper in the lung, this localization is not possible without prior invasive marking techniques...

journal_title：Physics in medicine and biology

authors： Lesage AJ,Rajaram R,Tam AL,Rigaud BS,Brock KK,Rice DC,Cazoulat G

更新日期：2020-09-09 00:00:00

abstract：:We have measured the bulk optical properties of healthy female breast tissues in vivo in the parallel plate, transmission geometry. Fifty-two volunteers were measured. Blood volume and blood oxygen saturation were derived from the optical property data using a novel method that employed a priori spectral information t...

journal_title：Physics in medicine and biology

authors： Durduran T,Choe R,Culver JP,Zubkov L,Holboke MJ,Giammarco J,Chance B,Yodh AG

更新日期：2002-08-21 00:00:00

abstract：:The reference levels and maximum permissible exposure values for magnetic fields that are currently used have been derived from basic restrictions under the assumption of upright standing body models in a standard posture, i.e. with arms laterally down and without contact with metallic objects. Moreover, if anatomical...

journal_title：Physics in medicine and biology

authors： Schmid G,Hirtl R

更新日期：2016-06-21 00:00:00

abstract：:Successful radiotherapy treatment depends heavily upon the accuracy of patient geometry captured during treatment simulation using computed tomography (CT) scans. Radiotherapy patients are often scanned under free breathing, and respiratory motion can cause severe artifacts in CT scans, including shortening, elongatio...

journal_title：Physics in medicine and biology

authors： Lewis JH,Jiang SB

更新日期：2009-02-07 00:00:00

abstract：:At the UMC Utrecht a prototype MR-linac has been installed. The system consists of an 8 MV Elekta linear accelerator and a 1.5 T Philips MRI system. This paper investigates the performance of the IC PROFILER™, a multi-axis ionization chamber array, in a 1.5 T magnetic field. The influence of the magnetic field on the ...

journal_title：Physics in medicine and biology

authors： Smit K,Kok JG,Lagendijk JJ,Raaymakers BW

更新日期：2014-04-07 00:00:00

abstract：:Within an epidemiological study regarding the correlation between skin pathologies and personal ultraviolet (UV) exposure due to solar radiation, 14 field campaigns using polysulphone (PS) dosemeters were carried out at three different Italian sites (urban, semi-rural and rural) in every season of the year. A polysulp...

journal_title：Physics in medicine and biology

authors： Casale GR,Borra M,Colosimo A,Colucci M,Militello A,Siani AM,Sisto R

更新日期：2006-09-07 00:00:00

abstract：:The problem of fluorescence diffuse optical tomography consists in localizing fluorescent markers from near-infrared light measurements. Among the different available acquisition modalities, the time-resolved modality is expected to provide measurements of richer information content. To extract this information, the m...

journal_title：Physics in medicine and biology

authors： Ducros N,Hervé L,Da Silva A,Dinten JM,Peyrin F

更新日期：2009-12-07 00:00:00

abstract：:Pediatric patients who received radiation therapy are at risk of developing side effects such as radiogenic second cancer. We compared proton and photon therapies in terms of the predicted risk of second cancers for a 4 year old medulloblastoma patient receiving craniospinal irradiation (CSI). Two CSI treatment plans ...

journal_title：Physics in medicine and biology

authors： Zhang R,Howell RM,Giebeler A,Taddei PJ,Mahajan A,Newhauser WD

更新日期：2013-02-21 00:00:00

abstract：:Shear wave elastography (SWE) is a potential tool to non-invasively assess cardiac muscle stiffness. This study focused on the effect of the orthotropic material properties and mechanical loading on the performance of cardiac SWE, as it is known that these factors contribute to complex 3D anisotropic shear wave propag...

journal_title：Physics in medicine and biology

authors： Caenen A,Pernot M,Peirlinck M,Mertens L,Swillens A,Segers P

更新日期：2018-03-23 00:00:00

abstract：:A solid dynamic phantom with tissue-like optical properties is presented, which contains seven discrete targets impregnated with thermochromic pigment located at different depths from the surface. Changes in absorption are obtained in response to localized heating of the targets, simulating haemodynamic changes occurr...

journal_title：Physics in medicine and biology

authors： Correia T,Banga A,Everdell NL,Gibson AP,Hebden JC

更新日期：2009-10-21 00:00:00

abstract：:Electromagnetic tracking technology is primarily used for continuous prostate localization during radiotherapy, but offers potential value for evaluation of dosimetric coverage and adequacy of treatment for dynamic targets. We developed a highly automated method for daily computation of cumulative dosimetric effects o...

journal_title：Physics in medicine and biology

authors： Noel CE,Santanam L,Olsen JR,Baker KW,Parikh PJ

更新日期：2010-01-07 00:00:00

abstract：:The practical use of a discrete vessel thermal model for hyperthermia treatment planning requires a number of choices with respect to the unknown part of the patient's vasculature. This work presents a study of the thermal effects of blood flow in a simple tissue geometry with a detailed artificial vessel network. The...

journal_title：Physics in medicine and biology

authors： Van Leeuwen GM,Kotte AN,Raaymakers BW,Lagendijk JJ

更新日期：2000-04-01 00:00:00