Comparison of risk of radiogenic second cancer following photon and proton craniospinal irradiation for a pediatric medulloblastoma patient.

abstract：:A new multiplicative correction factor for tissue heterogeneities based on an exact expression for homogeneous non-unit-density media is proposed. O'Connor's density scaling theorem is invoked to evaluate the medium-specific tissue-maximum ratios used in the exact formulation. Monte Carlo calculations were performed a...

journal_title：Physics in medicine and biology

authors： Petti PL,Siddon RL,Bjärngard BE

更新日期：1986-10-01 00:00:00

abstract：:A Geiger-mode avalanche photodiode (Si-PM) is a promising photodetector for PET, especially for use in a magnetic resonance imaging (MRI) system, because it has high gain and is less sensitive to a static magnetic field. We developed a Si-PM-based depth-of-interaction (DOI) PET system for small animals. Hamamatsu 4 × ...

journal_title：Physics in medicine and biology

authors： Yamamoto S,Imaizumi M,Watabe T,Watabe H,Kanai Y,Shimosegawa E,Hatazawa J

更新日期：2010-10-07 00:00:00

abstract：:The theory of task-based assessment of image quality is reviewed in the context of imaging with ionizing radiation, and objective figures of merit (FOMs) for image quality are summarized. The variation of the FOMs with the task, the observer and especially with the mean number of photons recorded in the image is discu...

journal_title：Physics in medicine and biology

authors： Barrett HH,Myers KJ,Hoeschen C,Kupinski MA,Little MP

更新日期：2015-01-21 00:00:00

abstract：:Irreversible electroporation (IRE) is a minimally invasive tumor therapy using pulsed electric field with high intensity while the important tissues such as blood vessel, bile duct, and nerve are preserved. In addition to ablation area, reversible electroporation (RE) region is also generated using needle electrodes f...

journal_title：Physics in medicine and biology

authors： Lv Y,Tang X,Peng W,Cheng X,Chen S,Yao C

更新日期：2020-10-14 00:00:00

abstract：:Inverse treatment planning in intensity modulated particle therapy (IMPT) with scanned carbon-ion beams is currently based on the optimization of RBE-weighted dose to satisfy requirements of target coverage and limited toxicity to organs-at-risk (OARs) and healthy tissues. There are many feasible IMPT plans that meet ...

journal_title：Physics in medicine and biology

authors： Burigo LN,Ramos-Méndez J,Bangert M,Schulte RW,Faddegon B

更新日期：2019-01-04 00:00:00

abstract：:The reproducibility of polyacrylamide gel (PAG) dosimetry has been evaluated when used to verify two radiotherapy treatment plans of increasing complexity. The plans investigated were a three-field coplanar arrangement, using the linac jaws for field shaping, and a four-field, conformal, non-coplanar plan using precis...

journal_title：Physics in medicine and biology

authors： Cosgrove VP,Murphy PS,McJury M,Adams EJ,Warrington AP,Leach MO,Webb S

更新日期：2000-05-01 00:00:00

abstract：:The metabolic content of urine from NIH III nude mice (n = 22) was analysed before and after inoculation with human glioblastoma multiforme (GBM) cancer cells. An age- and gender-matched control population (n = 14) was also studied to identify non-tumour-related changes. Urine samples were collected daily for 6 weeks,...

journal_title：Physics in medicine and biology

authors： Moroz J,Turner J,Slupsky C,Fallone G,Syme A

更新日期：2011-02-07 00:00:00

abstract：:Knowledge of what dose-volume histograms can be expected for a previously unseen patient could increase consistency and quality in radiotherapy treatment planning. We propose a machine learning method that uses previous treatment plans to predict such dose-volume histograms. The key to the approach is the framing of d...

journal_title：Physics in medicine and biology

authors： Skarpman Munter J,Sjölund J

更新日期：2015-09-07 00:00:00

abstract：:We present the results of utilizing aligned anatomical information from CT images to locally adjust image smoothness during the reconstruction of three-dimensional (3D) whole-body positron emission tomography (PET) data. The ability of whole-body PET imaging to detect malignant neoplasms is becoming widely recognized....

journal_title：Physics in medicine and biology

authors： Comtat C,Kinahan PE,Fessler JA,Beyer T,Townsend DW,Defrise M,Michel C

更新日期：2002-01-07 00:00:00

abstract：:The architecture of multi-layer imagers (MLIs) can be exploited to provide megavoltage spectral imaging (MVSPI) for specific imaging tasks. In the current work, we investigated bone suppression and gold fiducial contrast enhancement as two clinical tasks which could be improved with spectral imaging. A method based on...

journal_title：Physics in medicine and biology

authors： Myronakis M,Hu YH,Fueglistaller R,Wang A,Baturin P,Huber P,Morf D,Star-Lack J,Berbeco R

更新日期：2018-05-10 00:00:00

abstract：:Various lead attenuation techniques to determine the fast neutron sensitivity kU of a photon dosemeter are reviewed and a modified method is proposed to determine the kU value of a commercially available Geiger--Müller detector. The dependence on the 'effective' photon energy of the gamma-component of the mixed n--gam...

journal_title：Physics in medicine and biology

authors： Hough JH

更新日期：1979-07-01 00:00:00

abstract：:The accurate determination of mean ionization potential (I m) has the potential to reduce range uncertainty based margins and therefore allow for more focal treatments in proton radiotherapy. Many methods have been proposed to reduce uncertainty in I m and stopping power ratios (SPR), each with varying degrees of accu...

journal_title：Physics in medicine and biology

authors： Sudhyadhom A

更新日期：2017-10-27 00:00:00

abstract：:This paper presents a method to experimentally validate the beam quality correction factors (kQ) tabulated in IAEA TRS-398 for proton beams and to determine the kQ of non-tabulated ionization chambers (based on the already tabulated values). The method is based exclusively on ionometry and it consists in comparing the...

journal_title：Physics in medicine and biology

authors： Gomà C,Hofstetter-Boillat B,Safai S,Vörös S

更新日期：2015-04-21 00:00:00

abstract：:Methods based on magnetic resonance imaging for the measurement of three-dimensional distributions of radiation dose are highly developed. However, relatively little work has been done on optical computed tomography (OCT). This paper describes a new OCT scanner based on a broad beam light source and a two-dimensional ...

journal_title：Physics in medicine and biology

authors： Doran SJ,Koerkamp KK,Bero MA,Jenneson P,Morton EJ,Gilboy WB

更新日期：2001-12-01 00:00:00

abstract：:Models of the electrical properties of biological tissue have been the subject of many studies. These models have sought to explain aspects of the dielectric dispersion of tissue. This paper develops a mathematical model of the complex permittivity of tissue as a function of frequency f, in the range 10(4) < f < 10(7)...

journal_title：Physics in medicine and biology

authors： Smye SW,Evans CJ,Robinson MP,Sleeman BD

更新日期：2007-12-07 00:00:00

abstract：:Few quantitative data are available on the kinetics of polymerization reactions in polymer gel (PAG) dosimeters and their long-term stability. Post-irradiation polymerization reactions have been found to continue for several weeks, posing questions regarding dosimeter stability and its achievement. In this paper we re...

journal_title：Physics in medicine and biology

authors： McJury M,Oldham M,Leach MO,Webb S

更新日期：1999-08-01 00:00:00

abstract：:At the UMC Utrecht a prototype MR-linac has been installed. The system consists of an 8 MV Elekta linear accelerator and a 1.5 T Philips MRI system. This paper investigates the performance of the IC PROFILER™, a multi-axis ionization chamber array, in a 1.5 T magnetic field. The influence of the magnetic field on the ...

journal_title：Physics in medicine and biology

authors： Smit K,Kok JG,Lagendijk JJ,Raaymakers BW

更新日期：2014-04-07 00:00:00

abstract：:Contrast-enhanced ultrasound (US) imaging is potentially applicable to the investigation of vascular disorders of the testis. We investigated the ability of two automated computer algorithms to analyse contrast-enhanced pulse inversion US data in a rabbit model of unilateral testicular ischaemia and to correctly deter...

journal_title：Physics in medicine and biology

authors： Thierman JS,Clement GT,Kalish LA,O'Kane PL,Frauscher F,Paltiel HJ

更新日期：2006-07-21 00:00:00

abstract：:A method was developed to quantify the intensity of tissue staining using a CCD (charge-coupled device) camera. Reflection spectra of NBT-stained (nitro-blue tetrazolium-stained) and unstained myocardium were recorded via fibre optics coupled to a CCD camera, connected to a microcomputer. The calculation of the intens...

journal_title：Physics in medicine and biology

authors： Schröder T,Koch G,Schnabel PA,Hering JP,Bretschneider HJ,Richter J,Hellige G

更新日期：1991-06-01 00:00:00

abstract：:Positron emission tomography (PET) iterative 3D reconstruction is a very computational demanding task. One of the main issues of the iterative reconstruction concerns the management of the system response matrix (SRM). The SRM models the relationship between the projection and the voxel space and its memory footprint ...

journal_title：Physics in medicine and biology

authors： Camarlinghi N,Sportelli G,Guerra AD,Belcari N

更新日期：2018-09-28 00:00:00

abstract：:In radiofrequency (RF) ablation or hyperthermia, internal temperature measurements and tissue property imaging are important to control their outputs and assess the treatment effect. Recently, magnetic resonance electrical impedance tomography (MREIT), as a non-invasive imaging method of internal conductivity distribu...

journal_title：Physics in medicine and biology

authors： Oh TI,Kim HJ,Jeong WC,Chauhan M,Kwon OI,Woo EJ

更新日期：2013-04-21 00:00:00

abstract：:Developments in positron emission tomography (PET) technology have resulted in systems with finer detector elements designed to further improve spatial resolution. However, there is a limit to what extent reducing detector element size will improve spatial resolution in PET. The spatial resolution of PET imaging is li...

journal_title：Physics in medicine and biology

authors： Levin CS,Hoffman EJ

更新日期：1999-03-01 00:00:00

abstract：:A new hybrid imaging-treatment modality, the MRI-Linac, involves the irradiation of the patient in the presence of a strong magnetic field. This field acts on the charged particles, responsible for depositing dose, through the Lorentz force. These conditions require a dose calculation engine capable of taking into con...

journal_title：Physics in medicine and biology

authors： Hissoiny S,Raaijmakers AJ,Ozell B,Després P,Raaymakers BW

更新日期：2011-08-21 00:00:00

abstract：:To increase the scanning speed of cone-beam CT, a scanning configuration with three pairs of x-ray sources and panel detectors was proposed. In this paper, we apply the M-line-based backprojected filtration algorithm to this scanning configuration and propose a fast implementation for this algorithm. Compared with exi...

journal_title：Physics in medicine and biology

authors： Zhao Y,Zhu Y,Zhang P

更新日期：2010-12-07 00:00:00

abstract：:Cell experiments have shown the proton relative biological effectiveness (RBE) to vary with dose and linear energy transfer (LET), which has led to development of variable RBE models. The RBE is normally estimated from two independent functions, the RBEmax and RBEmin, describing the extreme RBE at low and high doses. ...

journal_title：Physics in medicine and biology

authors： Rørvik E,Thörnqvist S,Ytre-Hauge KS

更新日期：2019-09-23 00:00:00

abstract：:It is important to assess the viability of extremity soft tissues, as this component is often the determinant of the final outcome of fracture treatment. Microwave tomography (MWT) and sensing might be able to provide a fast and mobile assessment of such properties. MWT imaging of extremities possesses a complicated, ...

journal_title：Physics in medicine and biology

authors： Semenov S,Kellam J,Althausen P,Williams T,Abubakar A,Bulyshev A,Sizov Y

更新日期：2007-09-21 00:00:00

abstract：:The measurand relevant for the dosimetry for radiation therapy is the absorbed dose to water, DW. The Physikalisch-Technische Bundesanstalt (PTB) is establishing a secondary standard for DW for high-energy photon and electron radiation based on electron spin resonance (ESR) of the amino acid alanine. For practical app...

journal_title：Physics in medicine and biology

authors： Anton M

更新日期：2008-03-07 00:00:00

abstract：:Many models exist for predicting toxicities based on dose-volume histograms (DVHs) or dose-surface histograms (DSHs). This approach has several drawbacks as firstly the reduction of the dose distribution to a histogram results in the loss of spatial information and secondly the bins of the histograms are highly correl...

journal_title：Physics in medicine and biology

authors： Buettner F,Gulliford SL,Webb S,Partridge M

更新日期：2011-04-07 00:00:00

abstract：BACKGROUND:During transcranial electrical stimulation (tES), including transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS), current density concentration around the electrode edges that is predicted by simplistic skin models does not match experimental observations of ...

journal_title：Physics in medicine and biology

authors： Khadka N,Bikson M

更新日期：2020-09-11 00:00:00

abstract：:The whole prostatic volume (PV) is an important indicator for benign prostate hyperplasia. Correlating the PV with other clinical parameters in a population-based prospective cohort study (SHIP-2) requires valid prostate segmentation in a large number of whole-body MRI scans. The axial proton density fast spin echo fa...

journal_title：Physics in medicine and biology

authors： Habes M,Schiller T,Rosenberg C,Burchardt M,Hoffmann W

更新日期：2013-09-07 00:00:00