Evolving management of symptomatic chronic subdural hematoma: experience of a single institution and review of the literature.


OBJECTIVE:Chronic subdural hematoma (cSDH) has an increasing incidence and results in high morbidity and mortality. We review here the 10-year experience of a single institution and the literature regarding the treatment and major associations of cSDH. METHODS:We retrospectively reviewed all cSDHs surgically treated from 2000 to 2010 in the New York Harbor Health Care System to evaluate the duration from admission to treatment, type of treatment, length of stay (LOS) in critical care, LOS in the hospital, and recurrence. The literature was reviewed with regards to incidence, associations, and treatment of cSDH. RESULTS:From 2000 to 2008, 44 patients were treated with burr holes (BHs). From 2008 to 2010, 29 patients were treated with twist-drill evacuation (subdural evacuating port system, SEPS). Four patients from each group were readmitted for reoperation (9% vs 14%; P = 0.53). The average time to intervention for SEPS (11.2 ± 15.3 hours) was faster than for BHs (40.3 ± 69.1 hours) (P = 0.02). The total hospital LOS was shorter for SEPS (9.3 ± 6.8 days) versus BHs (13.4 ± 10.2 days) (P = 0.04); both were significantly longer than for a brain tumor patient undergoing craniotomy (7.0 ± 0.5 days, n = 94, P < 0.01). CONCLUSION:Despite decreasing LOSs as treatment for cSDH evolved from BHs to SEPS, the LOS for a cSDH is still longer than that of a patient undergoing craniotomy for brain tumor. We noted 11% recurrence in our series of patients, which included individuals who recurred as late as 3 years after initial diagnosis.


Neurol Res


Neurological research


Balser D,Rodgers SD,Johnson B,Shi C,Tabak E,Samadani U




Has Abstract


2013-04-01 00:00:00












  • The effects of human corticotrophin releasing factor on motor and cognitive deficits after impact acceleration injury.

    abstract::Corticotrophin releasing factor has been shown in several models of tissue injury to be an effective treatment for edema. In a previous study we demonstrated this ability in two models of traumatic brain injury (TBI). The aim of this study was to assess whether human corticotrophin releasing factor (hCRF) could additi...

    journal_title:Neurological research

    pub_type: 杂志文章


    authors: Beaumont A,Marmarou C,Marmarou A

    更新日期:2000-10-01 00:00:00

  • Endovascular thrombolysis and stenting of a middle cerebral artery occlusion beyond 6 hours post-attack: special reference to the usefulness of diffusion-perfusion MRI.

    abstract::Intra-arterial thrombolysis and percutaneous angioplasty is feasible in patients with acute middle cerebral artery (MCA) occlusion limited to 6 hours post-ictus, but there are some limitations such as reocclusion or hemorrhagic complications. In this report, we describe a stent placement in the treatment of a refracto...

    journal_title:Neurological research

    pub_type: 杂志文章


    authors: Ahn JY,Han IB,Chung SS,Chung YS,Kim SH,Yoon PH

    更新日期:2006-12-01 00:00:00

  • Anesthetic propofol normalized the increased release of glutamate and γ-amino butyric acid in hippocampus after paradoxical sleep deprivation in rats.

    abstract:OBJECTIVE:Multiple lines of evidence suggest that general anesthesia helps the recovery from sleep deprivation. However, little is known about the underlying neurochemical mechanisms. In the current study, we investigated the effect of anesthetic propofol on the release of glutamate (Glu) and γ-amino butyric acid (GABA...

    journal_title:Neurological research

    pub_type: 杂志文章


    authors: Xie F,Li X,Bao M,Shi R,Yue Y,Guan Y,Wang Y

    更新日期:2015-01-01 00:00:00

  • Immunomodulatory effectiveness of azithromycin in prevention of postlaminectomy epidural fibrosis.

    abstract:OBJECTIVE:One of the important causes of failed back surgery is the extensive peridural fibrosis collecting in the surgical field after spinal surgeries. Today we know that inflammatory mechanisms mediated by the immune system of the body plays an important role in generation of fibrosis. Azithromycin, a macrolide anti...

    journal_title:Neurological research

    pub_type: 杂志文章


    authors: Emmez H,Börcek AÖ,Durdağ E,Uyar PG,Kaymaz M,Aykol S

    更新日期:2011-05-01 00:00:00

  • Sonographic and electrophysiological detection in patients with carpal tunnel syndrome.

    abstract:OBJECTIVES:To assess prospectively the significance of sonographic measurements of the median nerve in the diagnosis of carpal tunnel syndrome (CTS), to look for proper parameters and cutoff values for the sonographic diagnosis, and to correlate with the electrophysiological findings. MATERIALS AND METHODS:This study ...

    journal_title:Neurological research

    pub_type: 杂志文章


    authors: Guan J,Ji F,Chen W,Chu H,Lu Z

    更新日期:2011-11-01 00:00:00

  • Anterior fossa dural arteriovenous malformation discovered by means of PW-Doppler examination.

    abstract::One case of dural arteriovenous malformation in the base of the anterior cranial fossa is reported. It was discovered by means of a PW-Doppler examination of angular branch of the ophthalmic artery in a patient under observation for hypertrophy of a superficial temporal artery. The nidus was located in the region of t...

    journal_title:Neurological research

    pub_type: 杂志文章


    authors: Fiori L,Parenti G,Puglioli M,Padolecchia R

    更新日期:1995-06-01 00:00:00

  • Characterization of the anxiolytic and sedative profile of JM-20: a novel benzodiazepine-dihydropyridine hybrid molecule.

    abstract:OBJECTIVES:The aim of this study was to investigate the effects of oral administration of a novel benzodiazepine derivative, JM-20, on the neurological behavior of different rodent models, focusing on the GABAergic effect. We have also investigated the acute toxicity of oral administration of JM-20 in mice. METHODS:Mi...

    journal_title:Neurological research

    pub_type: 杂志文章


    authors: Figueredo YN,Rodríguez EO,Reyes YV,Domínguez CC,Parra AL,Sánchez JR,Hernández RD,Verdecia MP,Pardo Andreu GL

    更新日期:2013-10-01 00:00:00

  • Supergiant anterior circulation aneurysms.

    abstract::Six cases of very large anterior circulation intracranial aneurysms are presented. Aneurysms of 53-84 mm in three female and two male adults and a 40 mm lesion in a seven week infant were successfully excised. Three patients tolerated trial intraluminal balloon occlusion preoperatively and underwent subsequent parent ...

    journal_title:Neurological research

    pub_type: 杂志文章


    authors: Cahill DW

    更新日期:1992-01-01 00:00:00

  • Comparison of triphenyltetrazolium dye with light microscopic evaluation in a rabbit model of acute cerebral ischaemia.

    abstract::The present study was performed to compare brain infarct size assessment by routine histology (haematoxylin and eosin) and by 2,3,5-triphenyltetrazolium chloride staining techniques. New Zealand white rabbits were subjected to autologous clot embolization to the anterior circulation of the brain. After a study period ...

    journal_title:Neurological research

    pub_type: 杂志文章


    authors: Bednar MM,Fanburg JC,Anderson ML,Raymond SJ,Dooley RH,Gross CE

    更新日期:1994-04-01 00:00:00

  • Brain tissue oxygenation monitoring supplementary to somatosensory evoked potential monitoring for aneurysm surgery. Initial clinical experience.

    abstract::The object of the study was to evaluate brain tissue oxygenation (p(ti)O2) for intra-operative monitoring of critical ischemic events during early cerebral aneurysm surgery of the anterior circulation supplementary to somatosensory evoked potentials (SEPs). P(ti)O2 was continuously evaluated during surgery for an intr...

    journal_title:Neurological research

    pub_type: 临床试验,杂志文章


    authors: Szelényi A,Jung CS,Schön H,Seifert V

    更新日期:2002-09-01 00:00:00

  • The changes of systemic immune responses during the neuroprotection induced by remote ischemic postconditioning against focal cerebral ischemia in mice.

    abstract::Objective: Remote limb ischemic postconditioning (RIPostC) protects the brain from damage induced by transient focal ischemia/reperfusion. However, the underlying mechanism remains unclear. Methods: RIPostC induced by 10 min of occlusion and another 10 min releasing of blood flow for three cycles in the hind limbs was...

    journal_title:Neurological research

    pub_type: 杂志文章


    authors: Liu C,Yang J,Zhang C,Geng X,Zhao H

    更新日期:2019-01-01 00:00:00

  • Blood-brain barrier restoration following cold injury.

    abstract::Cerebral blood flow (CBF), 113mIndium-DPTA, and 14C-glucose extraction were measured simultaneously in rat brain from 2 to 58 days following a thermal insult. In the early stage of a cold induced lesion (2 days), the blood-brain barrier (BBB) was disrupted with resulting leakage and diffusionary loss of both glucose a...

    journal_title:Neurological research

    pub_type: 杂志文章


    authors: Pollay M,Stevens FA

    更新日期:1980-01-01 00:00:00

  • Rebleeding of intracranial dissecting aneurysm in the vertebral artery following proximal clipping.

    abstract::We describe a case of rebleeding from an intracranial vertebral dissecting aneurysm following proximal clipping. This case suggests that proximal clipping alone may not be an adequate surgical procedure to prevent rebleeding. Surgical treatment of intracranial dissecting aneurysms in the vertebral artery presenting as...

    journal_title:Neurological research

    pub_type: 杂志文章,评审


    authors: Kawamata T,Tanikawa T,Takeshita M,Onda H,Takakura K,Toyoda C

    更新日期:1994-04-01 00:00:00

  • Literature review: sinus pericranii.

    abstract::Sinus pericranii is a rare circumscribed fluctuating vascular swelling of the scalp that communicates with the intracranial venous system. It has been associated with other intracranial vascular malformations. The tumour is usually round, fluctuant, nonpulsatile, and disappears with compression. Its size increases dur...

    journal_title:Neurological research

    pub_type: 杂志文章,评审


    authors: Vinas FC,Valenzuela S,Zuleta A

    更新日期:1994-12-01 00:00:00

  • Cortical spreading depression and the pathogenesis of brain disorders: a computational and neural network-based investigation.

    abstract::This paper reviews our recent studies of the role of cortical spreading depression (CSD) in the pathogenesis of brain disorders. Our investigation is a computational one, involving the development and utilization of a complex neuro-metabolic model of the interactions assumed to occur in the cortex during the passage o...

    journal_title:Neurological research

    pub_type: 杂志文章


    authors: Ruppin E,Reggia JA

    更新日期:2001-07-01 00:00:00

  • Silent cerebral ischemic lesions after carotid artery stenting with distal cerebral protection.

    abstract:OBJECTIVE:To evaluate by MR diffusion weighted image (DWI-MR) the presence of new ischemic cerebral lesions after carotid artery stenting (CAS) and distal cerebral protection, in patients with internal carotid artery (ICA) stenosis >70. METHODS:Sixty-seven CAS were performed under cerebral protection with a distal fil...

    journal_title:Neurological research

    pub_type: 杂志文章


    authors: González A,Piñero P,Martínez E,González-Marcos JR,Rafel E,Mayol A,Gil-Peralta A

    更新日期:2005-01-01 00:00:00

  • Change in cortical vein appearance on susceptibility-weighted MR imaging before and after carotid artery stenting.

    abstract:OBJECTIVES:Susceptibility-weighted (SW) magnetic resonance (MR) imaging is a sensitive test to detect intravenous deoxygenated blood. On SW images, dilated appearing draining veins in tissue with perfusion impairment occur due to an increase in intravenous deoxyhemoglobin levels, and could indicate poor perfusion areas...

    journal_title:Neurological research

    pub_type: 杂志文章


    authors: Sorimachi T,Morita K,Sasaki O,Koike T,Fujii Y

    更新日期:2011-04-01 00:00:00

  • Music training causes long-term enhancement of preschool children's spatial-temporal reasoning.

    abstract::Predictions from a structured cortical model led us to test the hypothesis that music training enhances young children's spatial-temporal reasoning. Seventy-eight preschool children participated in this study. Thirty-four children received private piano keyboard lessons, 20 children received private computer lessons, ...

    journal_title:Neurological research

    pub_type: 杂志文章


    authors: Rauscher FH,Shaw GL,Levine LJ,Wright EL,Dennis WR,Newcomb RL

    更新日期:1997-02-01 00:00:00

  • Motor cortex stimulation enhances motor recovery and reduces peri-infarct dysfunction following ischemic insult.

    abstract::Recovery of motor function following stroke is believed to be supported, at least in part, by functional compensation involving residual neural tissue. The present study used a rodent model of focal ischemia and intracortical microstimulation (ICMS) to examine the behavioral and physiological effects of cortical stimu...

    journal_title:Neurological research

    pub_type: 杂志文章


    authors: Kleim JA,Bruneau R,VandenBerg P,MacDonald E,Mulrooney R,Pocock D

    更新日期:2003-12-01 00:00:00

  • Management of neurocysticercosis.

    abstract:BACKGROUND:Neurocysticercosis is a parasitic infection of the central nervous system caused by the larval stage of the tapeworm Taenia solium and is the most common parasitic infection involving the human nervous system. Neurocysticercosis represents one of the most common causes of symptomatic epilepsy in developing c...

    journal_title:Neurological research

    pub_type: 杂志文章,评审


    authors: Ramírez-Zamora A,Alarcón T

    更新日期:2010-04-01 00:00:00

  • Near infrared technology in neuroscience: past, present and future.

    abstract:OBJECTIVE:To review past, present and future applications of near-infrared spectroscopy (NIRS) in clinical neuroscience. METHODS:The literature and personal experience of the authors were critically reviewed in order to provide a balanced overview of the basic principles, clinical validation, previous experience and c...

    journal_title:Neurological research

    pub_type: 杂志文章,评审


    authors: Calderon-Arnulphi M,Alaraj A,Slavin KV

    更新日期:2009-07-01 00:00:00

  • Rate of arterial occlusion in patients with acute ischemic stroke.

    abstract:OBJECTIVE:Computed tomographic angiography (CTA) was invented more than 20 years ago, but only gained acceptance recently, thanks to advancements in the computer technology. It can demonstrate areas of arterial stenosis or occlusion with accuracy nearly that of digital subtraction angiography (DSA). It is also able to ...

    journal_title:Neurological research

    pub_type: 杂志文章


    authors: Zubkov AY,Uschmann H,Rabinstein AA

    更新日期:2008-10-01 00:00:00

  • Diffusion tensor tractography to visualize axonal outgrowth and regeneration in a 4-cm reverse autograft sciatic nerve rabbit injury model.

    abstract:BACKGROUND:Diffusion tensor tractography (DTT) has recently been shown to accurately detect nerve injury and regeneration. This study assesses whether 7-tesla (7T) DTT imaging is a viable modality to observe axonal outgrowth in a 4 cm rabbit sciatic nerve injury model fixed by a reverse autograft (RA) surgical techniqu...

    journal_title:Neurological research

    pub_type: 杂志文章


    authors: Farinas AF,Pollins AC,Stephanides M,O'Neill D,Al-Kassis S,Esteve IVM,Colazo JM,Keller PR,Rankin T,Wormer BA,Kaoutzanis C,Dortch RD,Thayer WP

    更新日期:2019-03-01 00:00:00

  • Relationship between brain temperature, brain chemistry and oxygen delivery after severe human head injury: the effect of mild hypothermia.

    abstract::We studied brain temperature and the effect of mild hypothermia in 58 patients after severe head injury (SHI). Brain tissue oxygen tension (ptiO2), carbon dioxide tension (ptiCO2), tissuie pH (pHti) and temperature (T.br) were measured using a multiparameter probe. Microdialysis was performed to measure glucose, lacta...

    journal_title:Neurological research

    pub_type: 杂志文章


    authors: Soukup J,Zauner A,Doppenberg EM,Menzel M,Gilman C,Bullock R,Young HF

    更新日期:2002-03-01 00:00:00

  • Localization of bone marrow stromal cells in injured spinal cord treated by intravenous route depends on the hemorrhagic lesions in traumatized spinal tissues.

    abstract:OBJECTIVES:Bone marrow stromal cells (BMSCs) have been reported to improve movement deficit in adult rats with spinal cord injury (SCI). The purpose of this study is to determine the distribution of BMSCs in the spinal cord lesion of the contusion model of SCI. METHODS:Laminectomy was carried out at L1 vertebra level ...

    journal_title:Neurological research

    pub_type: 杂志文章


    authors: Khalatbary AR,Tiraihi T

    更新日期:2007-01-01 00:00:00

  • Microvascular and transcranial Doppler sonographic evaluation of cerebral aneurysm flow pattern.

    abstract::Ninety percent of cerebral aneurysms were diagnosed after their first rupture with consecutive subarachnoid haemorrhage. In order to detect the aneurysms before rupture investigation by transcranial Doppler sonography was used on the basis of intra-operative evaluation of the normal aneurysmal flow pattern. In 34 pati...

    journal_title:Neurological research

    pub_type: 杂志文章


    authors: Gilsbach JM,Harders AG

    更新日期:1989-03-01 00:00:00

  • Relief of intractable cancer pain by human chromaffin cell transplants: experience at two medical centers.

    abstract::In addition to its possible role as a replacement source in CNS degenerative diseases, neural transplantation may be used to augment the normal production of neuroactive substances. Our laboratory at the University of Illinois at Chicago has shown, in both acute and chronic pain models, that transplantation of adrenal...

    journal_title:Neurological research

    pub_type: 临床试验,杂志文章,多中心研究


    authors: Pappas GD,Lazorthes Y,Bès JC,Tafani M,Winnie AP

    更新日期:1997-02-01 00:00:00

  • Neuroprotective actions of 1-aminocyclopropanecarboxylic acid (ACPC): a partial agonist at strychnine-insensitive glycine sites.

    abstract::1-Aminocyclopropanecarboxylic acid is a high affinity ligand with partial agonist properties at strychnine-insensitive glycine sites associated with the N-methyl-D-aspartate subtype of glutamate receptors. Since occupation of these sites appears required for operation of N-methyl-D-aspartate, receptor coupled cation c...

    journal_title:Neurological research

    pub_type: 杂志文章


    authors: Fossom LH,Von Lubitz DK,Lin RC,Skolnick P

    更新日期:1995-08-01 00:00:00

  • Expression of metastasis suppressor gene maspin is reduced in breast cancer brain metastases and correlates with the estrogen receptor status.

    abstract:OBJECTIVES:The suppressor gene maspin (Serpin B5) is a promising candidate for future treatment. We have examined the messenger RNA (mRNA) and protein expression of maspin in normal breast tissue, breast cancer primaries, brain metastases and breast cancer cell lines. Results were compared to hormone receptor expressio...

    journal_title:Neurological research

    pub_type: 杂志文章


    authors: Stark AM,Schem C,Maass N,Hugo HH,Jonat W,Mehdorn HM,Held-Feindt J

    更新日期:2010-04-01 00:00:00

  • Reduced brain N-acetyl-aspartate in frontal lobes suggests neuronal loss in patients with amyotrophic lateral sclerosis.

    abstract::We performed proton magnetic resonance spectroscopy (1H-MRS) in three patients with amyotrophic lateral sclerosis (ALS) to evaluate the distribution and extent of cortical neuronal damage as demonstrated by decreased N-acetyl-aspartate (NAA) levels. We examined primary motor (precentral gyrus) and parietal neocortical...

    journal_title:Neurological research

    pub_type: 杂志文章


    authors: Giroud M,Walker P,Bernard D,Lemesle M,Martin D,Baudouin N,Brunotte F,Dumas R

    更新日期:1996-06-01 00:00:00