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Effects of manganese deficiency on serum hormones and biochemical markers of bone metabolism in chicks.

Abstract：

:In order to investigate the effect of manganese (Mn) deficiency on bone metabolism in chicks, ninety 1-day-old male Arbor Acre chicks were randomly divided into 3 groups and each group were given a diet having a different concentration of Mn (60 mg kg(-1), control group; 40 mg kg(-1), Mn-deficient group I; 8.7 mg kg(-1), Mn-deficient group II). The serum was collected at 42 days old. Tests were performed to evaluate the changes in the levels of PTH, CT, ALP, TrACP, HOP TNF-alpha, OC, Mn and Ca in the serum of the chicks and the results showed that the levels of CT, ALP, TrACP, HOP, and Mn decreased markedly (P < 0.05), while PTH, Ca, and TNF-alpha increased markedly (P < 0.05) due to manganese deficiency in the diet, which indicates that Mn deficiency results in disorder of bone regulatory hormones and enzymes of bone metabolism in the serum.

journal_name

J Bone Miner Metab

journal_title

Journal of bone and mineral metabolism

authors

Zhaojun W,Lin W,Zhenyong W,Jian W,Ran L

doi

10.1007/s00774-012-0417-6

subject

Has Abstract

pub_date

2013-05-01 00:00:00

pages

285-92

issue

3

eissn

0914-8779

issn

1435-5604

journal_volume

31

pub_type

杂志文章

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