Executive summary of clinical practice guide on fracture risk in lifestyle diseases.

abstract：INTRODUCTION:Aromatase inhibitors are known to accelerate bone loss in patients with breast cancer. However, how much AIs affect the efficacy of antiresorptive agents has not been studied. The study aimed to compare the effect of alendronate on bone mineral density (BMD) between patients with and without AI treatment. ...

journal_title：Journal of bone and mineral metabolism

authors： Kong SH,Kim JH,Kim SW,Shin CS

更新日期：2020-09-01 00:00:00

abstract：:A T869-->C polymorphism of the transforming growth factor-beta1 (TGF-beta1) gene is reported to be associated with genetic susceptibility to both osteoporosis and vertebral fractures. A low serum 25-hydroxyvitamin D [25(OH)D] level is known to be associated with a higher risk for hip fracture. This study aimed to asse...

journal_title：Journal of bone and mineral metabolism

authors： Mori S,Fuku N,Chiba Y,Tokimura F,Hosoi T,Kimbara Y,Tamura Y,Araki A,Tanaka M,Ito H

更新日期：2010-07-01 00:00:00

abstract：:The effects of basic fibroblast growth factor (bFGF) on osteogenic differentiation in-vivo were investigated using a rat bone marrow ablation model. bFGF was infused directly into rat femora for 6 days after bone marrow ablation. The contralateral femur was infused with vehicle only and used as control. Bone formation...

journal_title：Journal of bone and mineral metabolism

authors： Tanaka H,Wakisaka A,Ogasa H,Kawai S,Liang CT

更新日期：2003-01-01 00:00:00

abstract：:The dietary reference intake (DRI) of vitamin D for Korean children was reduced from 400 IU/day in 2005 to 200 IU/day in 2010. We evaluated the risk factors for low 25-hydroxyvitamin D [25(OH)D] status and its relationships with bone health in peripubertal nonobese children living in Seoul or Gyeonggi-do. One hundred ...

journal_title：Journal of bone and mineral metabolism

authors： Lee YA,Kim JY,Kang MJ,Chung SJ,Shin CH,Yang SW

更新日期：2013-05-01 00:00:00

abstract：:Concurrent use of bisphosphonate therapy reduces the anabolic effect of teriparatide. Consequently, in clinical practice bisphosphonates are discontinued and teriparatide therapy held for a few months to allow bone turnover to increase. We aimed to evaluate the effect of prior bisphosphonate exposure and the effect of...

journal_title：Journal of bone and mineral metabolism

authors： Keel C,Kraenzlin ME,Kraenzlin CA,Müller B,Meier C

更新日期：2010-01-01 00:00:00

abstract：:Sarcopenia is an age-related loss of skeletal muscle mass and strength. It has been widely recognized that low muscle mass was essential in the diagnosis of sarcopenia, whereas recent studies have emphasized the importance of muscle strength. In practice, muscle quality as well as muscle mass might determine the stren...

journal_title：Journal of bone and mineral metabolism

authors： Yakabe M,Hosoi T,Akishita M,Ogawa S

更新日期：2020-01-01 00:00:00

abstract：:We designed a randomized, double-blind, controlled clinical trial to compare the effect of two regimens for administering cholecalciferol on the serum 25-hydroxycholecalciferol [25(OH)D] levels and in the reversion of secondary hyperparathyroidism in the elderly living in a low-income housing unit in the city of Porto...

journal_title：Journal of bone and mineral metabolism

authors： Premaor MO,Scalco R,da Silva MJ,Froehlich PE,Furlanetto TW

更新日期：2008-01-01 00:00:00

abstract：:The MOVEMENT study was designed to assess the effectiveness of monthly intravenous ibandronate on bone mineral density (BMD) in daily clinical practice in Japanese patients with primary osteoporosis whose lumbar spine BMD did not increase despite oral bisphosphonate therapy. This study was a multicenter, prospective, ...

journal_title：Journal of bone and mineral metabolism

authors： Hagino H,Sakai A,Ikeda S,Imanishi Y,Tsurukami H,Nakajo S,Miyakoshi N

更新日期：2019-11-01 00:00:00

abstract：:The prevalence and pattern of joint involvement in radiographic hand osteoarthritis (OA) have been reported in Western populations, but similar data are lacking for Japanese. We examined this issue in 551 Japanese women aged > or = 40 years. Radiographs were obtained of both hands and graded according to the Kellgren-...

journal_title：Journal of bone and mineral metabolism

authors： Toba N,Sakai A,Aoyagi K,Yoshida S,Honda S,Nakamura T

更新日期：2006-01-01 00:00:00

abstract：:There is a lack of research on volumetric multi-slice CT (MSCT) application in hip densitometric assessment and geometric measures in elderly women with osteoporotic vertebral fractures. A total of 237 elderly women were divided into three groups based on BMD values of the lumbar spine (AP-SPINE) and/or the femoral ne...

journal_title：Journal of bone and mineral metabolism

authors： Wu SY,Qi J,Lu Y,Lan J,Yu JC,Wen LQ,Zhang ZL

更新日期：2010-11-01 00:00:00

abstract：:To screen a potential risk factor for femoral neck fracture, we characterized lumbar vertebral fractures in 120 patients with femoral neck fractures (19 men, 101 women; mean age, 78.7 years) by investigating the frequency of patients with lumbar vertebral fracture, the number of vertebral fractures per patient, and th...

journal_title：Journal of bone and mineral metabolism

authors： Kinoshita T,Ebara S,Kamimura M,Tateiwa Y,Itoh H,Yuzawa Y,Takahashi J,Takaoka K

更新日期：1999-01-01 00:00:00

abstract：:There is no well-established treatment for osteoporosis in male patients with leprosy, because no clinical trials have examined the efficacy of treatment on bone mineral density (BMD) or fracture incidence in patients with leprosy. In this study, we report a case of osteoporosis in a man with leprosy, treated by oral ...

journal_title：Journal of bone and mineral metabolism

authors： Kanaji A,Higashi M,Namisato M,Ando K,Nakagawa M,Yato Y,Ichinose H,Sakamaki T,Yamada H

更新日期：2005-01-01 00:00:00

abstract：:Quantitative ultrasound (QUS) is used for prediction for risks of osteoporotic fractures at various skeletal sites, irrespective of weight-bearing or non-weight-bearing skeletons. In the current study, we investigated the correlation between calcaneal QUS measurements (BUA, VOS, and Soundness) and volumetric trabecula...

journal_title：Journal of bone and mineral metabolism

authors： Hung VW,Qin L,Au SK,Choy WY,Leung KS,Leung PC,Cheng JC

更新日期：2004-01-01 00:00:00

abstract：:The purpose of this study was to investigate the relationship between intervertebral disk degeneration and bone mass. Magnetic resonance imaging was performed to evaluate lumbar disk degeneration according to Thompson's classification (grades 1 and 2, normal disk; grades 3, 4, and 5, degenerated disk), and bone minera...

journal_title：Journal of bone and mineral metabolism

authors： Nanjo Y,Morio Y,Nagashima H,Hagino H,Teshima R

更新日期：2003-01-01 00:00:00

abstract：:Osteoporosis is the most common bone disease in humans. During bone remodeling, specialized blood vessels influenced by the endothelial cells (CD31hiEmcnhi, also called type H cells) are formatted to supply nutrients. Reductions in vascular supply are associated with bone loss resulting in osteoporosis. Therefore, the...

journal_title：Journal of bone and mineral metabolism

authors： Zhu Y,Ruan Z,Lin Z,Long H,Zhao R,Sun B,Cheng L,Tang L,Xia Z,Li C,Zhao S

更新日期：2019-11-01 00:00:00

abstract：:Three-dimensional (3D) alteration of trabecular microarchitecture is a risk factor for vertebral fractures. Histomorphometry allows microarchitectural analysis of bone, but the necessity to perform a transiliac bone biopsy limits its use in large series of patients. X-Ray films are commonly used in routine practice an...

journal_title：Journal of bone and mineral metabolism

authors： Chappard D,Guggenbuhl P,Legrand E,Baslé MF,Audran M

更新日期：2005-01-01 00:00:00

abstract：:Nitrogen-containing bisphosphonates such as zoledronic acid (ZOL) and pamidronate have been widely and successfully used for the treatment of cancer patients with bone metastases and/or hypercalcemia. Accumulating recent reports have shown that cancer patients who have received these bisphosphonates occasionally manif...

journal_title：Journal of bone and mineral metabolism

authors： Kobayashi Y,Hiraga T,Ueda A,Wang L,Matsumoto-Nakano M,Hata K,Yatani H,Yoneda T

更新日期：2010-03-01 00:00:00

abstract：:We have been using hormone replacement therapy (HRT) as the treatment of choice for menopausal symptoms and osteoporosis. Estrogen increases bone mineral density (BMD) for 2 or 3 years, and only maintains BMD thereafter. In the present study, we investigated whether BMD improved with HRT in combination with vitamin K(...

journal_title：Journal of bone and mineral metabolism

authors： Hidaka T,Hasegawa T,Fujimura M,Sakai M,Saito S

更新日期：2002-01-01 00:00:00

abstract：:Fourier transform infrared spectroscopy and 31P solid-state nuclear magnetic resonance spectroscopy were used to determine if any structural or compositional differences in osteogenesis imperfecta (OI) bone mineral could be detected that might help to explain the bone fragility observed in this disease. A previous stu...

journal_title：Journal of bone and mineral metabolism

authors： Cassella JP,Barrie PJ,Garrington N,Ali SY

更新日期：2000-01-01 00:00:00

abstract：:Interleukin-11 (IL-11) is a bone marrow stromal fibroblast-derived cytokine with a wide spectrum of activities in different biological systems. IL-11 and IL-6 are two cytokines known to rely on osteoblast-osteoclast communication for their effects on osteoclast differentiation. Bone sialoprotein (BSP) is a mineralized...

journal_title：Journal of bone and mineral metabolism

authors： Matsumura H,Nakayama Y,Takai H,Ogata Y

更新日期：2015-03-01 00:00:00

abstract：:Bone microarchitecture of the iliac bone is used to characterize the properties of bone tissue in osteoporosis, particularly in pharmacological studies. Trabecular bone is known to be heterogeneous media. For a few years, the analysis of three-dimensional (3-D) bone microarchitecture has been based on micro-computed t...

journal_title：Journal of bone and mineral metabolism

authors： Chappard C,Marchadier A,Benhamou L

更新日期：2008-01-01 00:00:00

abstract：:Osteopathic changes sometimes occur in patients with complex regional pain syndrome (reflex sympathetic dystrophy and causalgia). We aimed to investigate whether such osteopathic changes occurred in rats with chronic constriction injury (CCI) of the sciatic nerve. A CCI of the sciatic nerve was established in a unilat...

journal_title：Journal of bone and mineral metabolism

authors： Suyama H,Moriwaki K,Niida S,Maehara Y,Kawamoto M,Yuge O

更新日期：2002-01-01 00:00:00

abstract：:Studies examining the effects of hypoxia upon osteoclast biology have consistently revealed a stimulatory effect; both osteoclast differentiation and resorption activity have been shown to be enhanced in the presence of hypoxia. In the present study we examined the effects of the hypoxia mimetics dimethyloxallyl glyci...

journal_title：Journal of bone and mineral metabolism

authors： Leger AJ,Altobelli A,Mosquea LM,Belanger AJ,Song A,Cheng SH,Jiang C,Yew NS

更新日期：2010-09-01 00:00:00

abstract：:Vertebral fractures are the most common complication associated with osteoporosis. The definition of prevalent or incident vertebral fractures is important in epidemiological evaluation and in clinical trials of osteoporosis treatment. There have been few reports regarding the morphometric cutoff criteria for incident...

journal_title：Journal of bone and mineral metabolism

authors： Fukunaga M,Nakamura T,Shiraki M,Kuroda T,Ohta H,Hosoi T,Orimo H

更新日期：2004-01-01 00:00:00

abstract：:Abeta-2M-amyloidosis is a type of systemic amyloidosis that is specifically seen in patients with chronic kidney diseases. The precursor protein of Abeta-2M-amyloid fibril is beta2-microglobulin, and its elevated serum level is the main cause of Abeta-2M-amyloidosis in patients with kidney failure. However, the precis...

journal_title：Journal of bone and mineral metabolism

authors： Kazama JJ,Yamamoto S,Takahashi N,Ito Y,Maruyama H,Narita I,Gejyo F

更新日期：2006-01-01 00:00:00

abstract：:Osteoporosis has a strong genetic component, but the genes involved are poorly defined. Genome-wide scans in multiple populations have identified chromosome 1p36 as one region linked to bone mineral density (BMD). The tumor necrosis factor receptor 2 (TNFR2) at 1p36 is a positional and functional candidate gene in ost...

journal_title：Journal of bone and mineral metabolism

authors： Huang QY,Shen H,Deng HY,Conway T,Elze L,Davies KM,Recker RR,Deng HW

更新日期：2006-01-01 00:00:00

abstract：:The impact of smoking on peak bone density has not been conclusively established. We examined how smoking exposure influences bone mineral density (BMD) or the risk of low bone status in premenopausal women. We conducted a baseline survey with a representative sample of Japanese women in 1996. The effect of current an...

journal_title：Journal of bone and mineral metabolism

authors： Tamaki J,Iki M,Sato Y,Kajita E,Kagamimori S,Kagawa Y,Yoneshima H

更新日期：2010-05-01 00:00:00

abstract：:Low levels of vitamin D nutrition (i.e., vitamin D insufficiency), which potentially cause osteoporosis, have been recognized as a common health problem for elderly people in European and North American countries, but there have been no studies on the prevalence of vitamin D insufficiency in Japan until recently. The ...

journal_title：Journal of bone and mineral metabolism

authors： Nakamura K

更新日期：2006-01-01 00:00:00

abstract：:Here we report the identification of two different mutations in chloride channel 7 gene in two unrelated patients with autosomal dominant osteopetrosis type II. We determined that one patient (a 32-year-old woman) carried a heterozygous gene for a R767W mutation in exon 24, and another patient (a 17-year-old boy) carr...

journal_title：Journal of bone and mineral metabolism

authors： Zhang ZL,He JW,Zhang H,Hu WW,Fu WZ,Gu JM,Yu JB,Gao G,Hu YQ,Li M,Liu YJ

更新日期：2009-01-01 00:00:00

abstract：:Measurements of bone biochemical markers are increasingly being used to evaluate the state of bone turnover in the management of bone metabolic diseases, especially osteoporosis. However, changes in the bone turnover rate vary with age. The aim of this study was to establish the laboratory reference range of serum bon...

journal_title：Journal of bone and mineral metabolism

authors： Pi YZ,Wu XP,Liu SP,Luo XH,Cao XZ,Xie H,Liao EY

更新日期：2006-01-01 00:00:00