Basic principles for generating motor output in the stomatogastric ganglion.

abstract：:As studied by single cell RT-PCR of pituitary hormones, we demonstrated that the pituitaries of rats and mice contain a subpopulation of cells that express two or more hormone phenotypes typically belonging to lineages that are branched separately early during embryonic development, such as glycoprotein hormone alpha-...

journal_title：Annals of the New York Academy of Sciences

authors： Denef C,Pals K,Hauspie A,Vankelecom H,Seuntjens E

更新日期：2005-04-01 00:00:00

abstract：:Molecular redundancy refers to the ability of genes to back up damaged genes or gene loss. Although this term is widely discussed in many scientific circles, the process is still ill-defined, as shown by reviewing examples from the literature. Exploring the collagen-induced arthritis model in the context of CD44 knock...

journal_title：Annals of the New York Academy of Sciences

authors： Naor D,Nedvetzki S,Assayag N,Thurmond RL,Huang JF,Turley EA

更新日期：2005-06-01 00:00:00

abstract：:The last decade has witnessed a surge in studies on steroid hormones of maternal origin present in avian eggs and affecting offspring development. The value of such studies for the understanding of maternal effects and individual differentiation is endorsed and a series of methodological and conceptual issues in the c...

journal_title：Annals of the New York Academy of Sciences

authors： Groothuis TG,von Engelhardt N

更新日期：2005-06-01 00:00:00

abstract：:Insulin-dependent diabetes mellitus (IDDM) is one of the most common chronic diseases. It is an autoimmune, polygenic disease, associated with several genes on different chromosomes. The most important gene is human leukocyte antigen (HLA), also known as major histocompatibility complex (MHC), which is located on chro...

journal_title：Annals of the New York Academy of Sciences

authors： Shtauvere-Brameus A,Ghaderi M,Rumba I,Sanjeevi CB

更新日期：2002-04-01 00:00:00

abstract：:The endothelial cells cultured in collagen gel caused upregulation of KDR expression, which resulted in an increase in tube formation. Endothelial cells exposed to high glucose (33 mmol/l) for 30 days increased the tube formation induced by VEGF, but not by serum and bFGF. Immunohistochemical study showed that KDR exp...

journal_title：Annals of the New York Academy of Sciences

authors： Murota SI,Onodera M,Morita I

更新日期：2000-05-01 00:00:00

abstract：:A recombinant major histocompatibility complex (MHC) with the same class III region as the NOD mouse, but different class II region from the NOD mouse was identified in the NON mouse, and NOD mice congenic for this recombinant MHC, NOD.NON-H2, was established. None of the congenic mice homozygous for the NON MHC devel...

journal_title：Annals of the New York Academy of Sciences

authors： Yamaji K,Ikegami H,Fujisawa T,Noso S,Nojima K,Babaya N,Itoi-Babaya M,Kobayashi M,Hiromine Y,Makino S,Ogihara T

更新日期：2006-10-01 00:00:00

abstract：:Astrakhan fever is a summer spotted fever resembling Mediterranean spotted fever, endemic in Astrakhan, a region of Russia located by the Caspian sea. Its agent is a spotted fever group rickettsia, member of the Rickettsia conorii complex, transmitted to humans by Rhipicephalus sanguineus and Rhipicephalus pumilio tic...

journal_title：Annals of the New York Academy of Sciences

authors： Fournier PE,Durand JP,Rolain JM,Camicas JL,Tolou H,Raoult D

更新日期：2003-06-01 00:00:00

abstract：:Cognitive neuroscience research has traditionally overlooked half of the population. Arguing that variability in ovarian hormones confounds empirical findings, girls and women have been excluded from research for decades. But times are changing. This review summarizes historical trends that have led to a knowledge gap...

journal_title：Annals of the New York Academy of Sciences

authors： Beltz AM,Moser JS

更新日期：2020-03-01 00:00:00

abstract：:Liquid membrane reactors are well known for metal extraction. This technology may also be applied to the immobilization of enzymes in enzyme emulsions. The use of liquid membrane reactors for enzymatic bioconversions has several advantages in comparison to solid membrane reactors and conventional immobilization techni...

journal_title：Annals of the New York Academy of Sciences

authors： Scheper T,Makryaleas K,Nowottny C,Likidis Z,Tsikas D,Schügerl K

更新日期：1987-01-01 00:00:00

abstract：:Pentazocine and cyclazocine are two benzomorphans that were synthesized by the late Sydney Archer in 1962. These benzomorphans were synthesized as part of an effort to develop analgesics with little or no abuse potential. Pentazocine is used as an analgesic, often in individuals who have sever pain or in those who hav...

journal_title：Annals of the New York Academy of Sciences

authors： Bidlack JM,McLaughlin JP,Wentland MP

更新日期：2000-01-01 00:00:00

abstract：:Recent cross-cultural studies of child development reveal that child rearing, while strikingly culturally variable, is everywhere designed to make the child's experience of important lessons constant, to link those lessons to emotional arousal, and to connect them to evaluations of the child's goodness and badness. Th...

journal_title：Annals of the New York Academy of Sciences

authors： Quinn N

更新日期：2003-10-01 00:00:00

abstract：:The purpose of this study was to quantify the changes in cell membrane conductance in response to electropermeabilization, which may elucidate the mechanisms of tissue injury resulting from high-voltage electrical shock. A high-speed, space-clamp and voltage-clamp experimental configuration was used. The pulse paramet...

journal_title：Annals of the New York Academy of Sciences

authors： Gowrishankar TR,Chen W,Lee RC

更新日期：1998-09-11 00:00:00

abstract：:Indirect and direct experimental evidence demonstrates that both the entry of extracellular calcium and the liberation of calcium from intracellular stores can contribute to an increase in free cytoplasmic calcium concentration in endothelial cells, which seems to be an essential step in the synthesis and/or release o...

journal_title：Annals of the New York Academy of Sciences

authors： Rubanyi GM,Vanhoutte PM

更新日期：1988-01-01 00:00:00

abstract：:Metacommunity ecology combines local (e.g., environmental filtering and biotic interactions) and regional (e.g., dispersal and heterogeneity) processes to understand patterns of species abundance, occurrence, composition, and diversity across scales of space and time. As such, it has a great potential to generalize an...

journal_title：Annals of the New York Academy of Sciences

authors： Chase JM,Jeliazkov A,Ladouceur E,Viana DS

更新日期：2020-06-01 00:00:00

abstract：:Blood-borne beta-amyloids (A beta s) could affect brain function by (1) crossing the BBB to directly interact with brain tissues or (2) altering BBB function by interacting with the brain capillaries that make up the BBB. Several radioactively labeled A beta s have been examined for such interactions. Blood-borne A be...

journal_title：Annals of the New York Academy of Sciences

authors： Banks WA,Kastin AJ,Maness LM,Banks MF,Shayo M,McLay RN

更新日期：1997-09-26 00:00:00

abstract：:A cholinergic hypofunction in Alzheimer's disease (AD) may lead to formation of beta-amyloids that might impair the coupling of M1 muscarinic ACh receptors (mAChRs) with G proteins. This disruption in coupling can lead to decreased signal transduction, to a reduction in levels of trophic amyloid precursor proteins (AP...

journal_title：Annals of the New York Academy of Sciences

authors： Fisher A,Michaelson DM,Brandeis R,Haring R,Chapman S,Pittel Z

更新日期：2000-01-01 00:00:00

abstract：:To investigate the role of zinc and copper in the development of pseudoexfoliation (PSX) syndrome, 34 cataract patients with PSX syndrome and 27 cataract patients without PSX syndrome were included in the study and groups were matched for age and gender. During the cataract surgery, lenses were obtained intraoperative...

journal_title：Annals of the New York Academy of Sciences

authors： Yildirim Z,Uçgun NI,Kiliç N,Gürsel E,Sepici-Dinçel A

更新日期：2007-04-01 00:00:00

abstract：:The slowpoke gene of Drosophila melanogaster encodes a Ca-activated K channel. This gene is expressed in neurons, muscles, tracheal cells, and the copper and iron cells of the midgut. The gene produces a large number of alternative products using tissue-specific transcriptional promoters and alternative mRNA splicing....

journal_title：Annals of the New York Academy of Sciences

authors： Atkinson NS,Brenner R,Bohm RA,Yu JY,Wilbur JL

更新日期：1998-11-16 00:00:00

abstract：:Nuclear factor-kappa B (NF-kappaB) is a transcription factor that resides in the cytoplasm of every cell and translocates to the nucleus when activated. Its activation is induced by a wide variety of agents including stress, cigarette smoke, viruses, bacteria, inflammatory stimuli, cytokines, free radicals, carcinogen...

journal_title：Annals of the New York Academy of Sciences

authors： Ahn KS,Aggarwal BB

更新日期：2005-11-01 00:00:00

abstract：:Oropharyngeal dysphagia (OD) is a swallowing disorder caused by congenital abnormalities and structural damage and disease-associated damage of the oral cavity, pharynx, and upper esophageal sphincter. Patients with OD lack the protective mechanisms necessary for effective swallowing, exhibiting difficulty controlling...

journal_title：Annals of the New York Academy of Sciences

authors： Rofes L,Clavé P,Ouyang A,Scharitzer M,Pokieser P,Vilardell N,Ortega O

更新日期：2013-10-01 00:00:00

abstract：:In this review, we present (1) the scientific basis for the use of high-dose immunosuppression followed by autologous peripheral blood hematopoietic stem cell transplantation for newly diagnosed type 1 diabetes (T1D); (2) an update of the clinical and laboratory outcome of 20 patients transplanted at the University Ho...

journal_title：Annals of the New York Academy of Sciences

authors： Voltarelli JC,Couri CE,Stracieri AB,Oliveira MC,Moraes DA,Pieroni F,Barros GM,Madeira MI,Malmegrim KC,Foss-Freitas MC,Simões BP,Foss MC,Squiers E,Burt RK

更新日期：2008-12-01 00:00:00

abstract：:Atrial fibrillation (AF), the highest occurring cardiac arrhythmia in the Western world, is associated with substantial morbidity and increased mortality. In spite of extensive research, the cause of atrial electrical remodeling, a major factor in the self-perpetuating nature of AF, is still unknown. Downregulation of...

journal_title：Annals of the New York Academy of Sciences

authors： Beharier O,Etzion Y,Levi S,Mor M,Mor M,Dror S,Kahn J,Katz A,Moran A

更新日期：2010-02-01 00:00:00

abstract：:Transcription regulatory factors are rapidly induced in brain by a wide variety of stimuli and may be important in coordinating changes in gene expression under-lying neuronal plasticity. Using in situ hybridization, we found that acute cocaine administration (20 mg/kg, intraperitoneally (i.p.)) produced a robust indu...

journal_title：Annals of the New York Academy of Sciences

authors： Humblot N,Thiriet N,Gobaille S,Aunis D,Zwiller J

更新日期：1998-05-30 00:00:00

abstract：:The SERMs currently in clinical practice or in late stages of clinical development have been studied primarily for their effects on the breast, cardiovascular, bone, and reproductive systems. The effect of SERMs on the hypothalamic-pituitary-gonadal (HPG) axis has not been the primary focus of the studies conducted th...

journal_title：Annals of the New York Academy of Sciences

authors： Plouffe L Jr,Siddhanti S

更新日期：2001-12-01 00:00:00

abstract：:SNAP-25 (synaptosomal-associated protein of 25 kDa) is a plasma membrane protein that, together with syntaxin and the synaptic vesicle protein VAMP/synaptobrevin, forms the SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) docking complex for regulated exocytosis. SNAP-25 also modulates dif...

journal_title：Annals of the New York Academy of Sciences

authors： Corradini I,Verderio C,Sala M,Wilson MC,Matteoli M

更新日期：2009-01-01 00:00:00

abstract：:An increasing amount of evidences suggests that galanin plays an important role in the regulation of reproduction in the rat. Galanin is colocalized with luteinizing hormone-releasing hormone (LHRH) in a subset of LHRH neurons, and the pattern of coexpression is sexually dimorphic, with a higher incidence of colocaliz...

journal_title：Annals of the New York Academy of Sciences

authors： Merchenthaler I

更新日期：1998-12-21 00:00:00

abstract：:Mouse models with targeted deletion of the genes encoding the enzyme 25-hydroxyvitamin D 1alpha-hydroxylase [1alpha(OH)ase], and the vitamin D receptor (VDR), have provided considerable insight into the regulation of mineral and skeletal physiology by 1,25-dihydroxyvitamin D [1,25(OH)(2)D]. Dietary manipulation induce...

journal_title：Annals of the New York Academy of Sciences

authors： Goltzman D

更新日期：2010-03-01 00:00:00

abstract：:An EEG profile for cannabis preparations equated for delta 9-THC activity has been defined in occasional cannabis users in New York and in long-term, high-dose hashish users in Athens. The EEG effects of enhanced alpha activity, decreased beta activity, and decreased mean frequency are dose dependent, both in intensit...

journal_title：Annals of the New York Academy of Sciences

authors： Fink M

更新日期：1976-01-01 00:00:00

abstract：:The CD27(+) IgD(+) B cell population, known as IgM memory, reduces with age. It is thought that this population is responsible for pneumococcal polysaccharide T-independent responses, and that the age-related reduction might be partially responsible for the increased susceptibility of older people to bacterial pathoge...

journal_title：Annals of the New York Academy of Sciences

authors： Martin V,Wu YC,Kipling D,Dunn-Walters DK

更新日期：2015-12-01 00:00:00

abstract：:Evolutionary theory is undergoing an intense period of discussion and reevaluation. This, contrary to the misleading claims of creationists and other pseudoscientists, is no harbinger of a crisis but rather the opposite: the field is expanding dramatically in terms of both empirical discoveries and new ideas. In this ...

journal_title：Annals of the New York Academy of Sciences

authors： Pigliucci M

更新日期：2009-06-01 00:00:00