Effects of acute and chronic inhalation of hashish, marijuana, and delta 9-tetrahydrocannabinol on brain electrical activity in man: evidence for tissue tolerance.

abstract：:Osteoclasts are cells of monocyte-macrophage origin that degrade bone matrix. Receptor activator of NF-kappaB ligand (RANKL) induces osteoclast formation in the presence of macrophage-colony-stimulating factor (M-CSF) and costimulatory signals. RANKL induces activation of the TNF receptor-associated factor 6 (TRAF6) a...

journal_title：Annals of the New York Academy of Sciences

authors： Takayanagi H

更新日期：2007-11-01 00:00:00

abstract：:One in 12 people worldwide suffers from diabetes and more than 90% of affected adult individuals are diagnosed with type 2 diabetes mellitus (T2DM). Obesity adds to the personal risk to develop T2DM, and both metabolic diseases are rampantly increasing worldwide. Over recent years, primary cilia have moved into the fo...

journal_title：Annals of the New York Academy of Sciences

authors： Volta F,Gerdes JM

更新日期：2017-03-01 00:00:00

abstract：:Disorientation may draw attention from other activities and its impact on cognition may cause pilot error and problems of concentration in dizzy patients. Tasks used to study the impact of disorientation include number processing, intelligence scales and Brookes matrices (reproduction of 2xD patterns of numbers vs. no...

journal_title：Annals of the New York Academy of Sciences

authors： Gresty MA,Golding JF

更新日期：2009-05-01 00:00:00

abstract：:MRI is a robust technology that allows for superior contrast of muscles, tissues, and bones within the body, which enables visualization of soft tissue pathology that cannot be seen with CT or plain film radiography. In order to appreciate the subtle (and sometimes not so subtle) intricacies of MRI, one must have a ba...

journal_title：Annals of the New York Academy of Sciences

authors： Khanna S,Crues JV 3rd

更新日期：2009-02-01 00:00:00

abstract：:Neuroendocrine tumors are very heterogeneous, develop from a variety of tissues, and can be difficult to diagnose. Without the clinical manifestation of metastases, it is often difficult to characterize them as malignant. Even so-called completely (R0) resected tumors can spread clinically visible metastases within a ...

journal_title：Annals of the New York Academy of Sciences

authors： Koch CA,Gimm O,Vortmeyer AO,Al-Ali HK,Lamesch P,Ott R,Kluge R,Bierbach U,Tannapfel A

更新日期：2006-08-01 00:00:00

abstract：:Fibronectin is a ubiquitous extracellular matrix (ECM) protein known to play a critical role in cell adhesion. In the present study we dissected the effects of glucocorticoids and cyclic adenosine 3',5'-monophosphate (cAMP) on FN expression in cultures of cytotrophoblasts isolated from human term placentas to identify...

journal_title：Annals of the New York Academy of Sciences

authors： Guller S,Wozniak R,Leibman MI,Lockwood CJ

更新日期：1994-09-30 00:00:00

abstract：:The osteoclast (OCL) is derived from the cells in monocyte-macrophage lineage. The earliest identifiable OCL precursor is the granulocyte-macrophage colony-forming unit (CFU-GM), which gives rise to granulocytes, monocytes, and OCL. CFU-GM-derived cells then differentiate to committed OCL precursors, which are post-mi...

journal_title：Annals of the New York Academy of Sciences

authors： Roodman GD

更新日期：2006-04-01 00:00:00

abstract：:Regardless of how creative, innovative, and elegant our computational methods, the ultimate proof of an algorithm's worth is the experimentally validated quality of its predictions. Unfortunately, this truism is hard to reduce to practice. Usually, modelers produce hundreds to hundreds of thousands of predictions, mos...

journal_title：Annals of the New York Academy of Sciences

authors： Stolovitzky G,Prill RJ,Califano A

更新日期：2009-03-01 00:00:00

abstract：:The characterization of the molecular mechanisms involved in low-oxygen chemotransduction has been an active field of research since the first description of an oxygen-sensitive K(+) channel in rabbit carotid body (CB) chemoreceptor cells. As a result, a large number of components of the transduction cascade, from O(2...

journal_title：Annals of the New York Academy of Sciences

authors： Gonzalez C,Vaquero LM,López-López JR,Pérez-García MT

更新日期：2009-10-01 00:00:00

abstract：:It is well known that women with breast cancer who undergo therapies beyond the surgical intervention (adjuvant chemotherapy, hormone therapy, or both) often suffer from the lack of estrogen, manifesting as climacteric symptoms in either treated premenopausal or postmenopausal women. Although HRT (hormone replacement ...

journal_title：Annals of the New York Academy of Sciences

authors： Xydakis AM,Sakkas EG,Mastorakos G

更新日期：2006-12-01 00:00:00

abstract：:Low- and high-frequency cortical oscillations play an important role in speech processing. Low-frequency neural oscillations in the delta (<4 Hz) and theta (4-8 Hz) bands entrain to the prosodic and syllabic rates of speech, respectively. Theta band neural oscillations modulate high-frequency neural oscillations in th...

journal_title：Annals of the New York Academy of Sciences

authors： Lizarazu M,Lallier M,Molinaro N

更新日期：2019-10-01 00:00:00

abstract：:SPAG-1, a sporozoite surface antigen of T. annulata, has previously been shown to elicit partial protection when used, as an hepatitis B core antigen fusion, to immunize cattle. The objective of this study was to try and improve the protective capacity of this antigen by enlisting different vaccine strategies. Cattle ...

journal_title：Annals of the New York Academy of Sciences

authors： Boulter NR,Brown CG,Kirvar E,Glass E,Campbell J,Morzaria S,Nene V,Musoke A,D'Oliveira C,Gubbels MJ,Jongejan F,Hall FR

更新日期：1998-06-29 00:00:00

abstract：:In the late 1970s, Wally Welker and his colleagues published a series of papers describing the first high-resolution physiological maps of tactile mossy fiber projections to the granule cell layer of the rat. Over the subsequent decade, his laboratory continued to explore the implications of these results for cerebell...

journal_title：Annals of the New York Academy of Sciences

authors： Bower JM

更新日期：2011-04-01 00:00:00

abstract：:The endothelial cells cultured in collagen gel caused upregulation of KDR expression, which resulted in an increase in tube formation. Endothelial cells exposed to high glucose (33 mmol/l) for 30 days increased the tube formation induced by VEGF, but not by serum and bFGF. Immunohistochemical study showed that KDR exp...

journal_title：Annals of the New York Academy of Sciences

authors： Murota SI,Onodera M,Morita I

更新日期：2000-05-01 00:00:00

abstract：:To investigate the role of poliovirus (PV) infection in the development of the post-polio syndrome (PPS), we studied the serum, spinal fluid, peripheral blood lymphocytes, and muscle from 47 patients with PPS. We found high titers of IgM PV antibodies (up to 1:250) in the serum of 6 patients, compared to very low tite...

journal_title：Annals of the New York Academy of Sciences

authors： Leon-Monzon ME,Dalakas MC

更新日期：1995-05-25 00:00:00

abstract：:The general aim of this experiment was to investigate the processes involved in reading musical notation and to study the relationship between written music and its auditory representation. Our main interest was to determine if musicians can develop expectancies for plausible or implausible auditory events on the sole...

journal_title：Annals of the New York Academy of Sciences

authors： Schön D,Besson M

更新日期：2003-11-01 00:00:00

abstract：:Mouse and human DNA sequences from centromeric and ribosomal domains were labeled with biotinylated deoxynucleotides and hybridized in situ to paraformaldehyde-fixed tissue culture cells. Centromeres were widely dispersed in most of these interphase nuclei. At late G2 phases of the cell cycle, centromeres appeared to ...

journal_title：Annals of the New York Academy of Sciences

authors： Manuelidis L

更新日期：1985-01-01 00:00:00

abstract：:Rats inoculated once with nicotinic acetylcholine receptor and adjuvants had two episodes of weakness, the first being acute and transient, starting on day 8, and remitting in a few days, the second, chronic, progressive, and appearing after day 20. In the acute phase, the compound action potential and twitch evoked ...

journal_title：Annals of the New York Academy of Sciences

authors： Lambert EH,Lindstrom JM,Lennon VA

更新日期：1976-01-01 00:00:00

abstract：:This study describes the features of the marginal zone (MZ) B cells of human tonsils and spleens and compares them with those of the follicular mantle (FM) B cells from the same tissues. The two B cell subpopulations displayed marked differences in phenotype, in response capacity to T cell-independent antigens and pol...

journal_title：Annals of the New York Academy of Sciences

authors： Dono M,Zupo S,Colombo M,Massara R,Gaidano G,Taborelli G,Ceppa P,Burgio VL,Chiorazzi N,Ferrarini M

更新日期：2003-04-01 00:00:00

abstract：:We have demonstrated a far more widespread and selective ischemic cell damage than previously thought. In area CA3, a distinct subpopulation of interneurons, characterized by their spiny dendrites and their calretinin content, was selectively vulnerable in the absence of any other CA3 involvement. In the dentate hilus...

journal_title：Annals of the New York Academy of Sciences

authors： Hsu M,Sik A,Gallyas F,Horváth Z,Buzsáki G

更新日期：1994-11-14 00:00:00

abstract：:The lysosomal system has often been considered a prominent morphologic marker of distressed or dying neurons. Lysosomes or their constituent hydrolases have been viewed in different neuropathologic states as either initiators and direct agents of cell death, agents of cellular repair and recompensation, effectors of e...

journal_title：Annals of the New York Academy of Sciences

authors： Nixon RA,Cataldo AM

更新日期：1993-05-28 00:00:00

abstract：:Nanomedicine is the application of nanotechnology to the discipline of medicine: the use of nanoscale materials for the diagnosis, monitoring, control, prevention, and treatment of disease. Nanomedicine holds tremendous promise to revolutionize medicine across disciplines and specialties, but this promise has yet to b...

journal_title：Annals of the New York Academy of Sciences

authors： Tinkle S,McNeil SE,Mühlebach S,Bawa R,Borchard G,Barenholz YC,Tamarkin L,Desai N

更新日期：2014-04-01 00:00:00

abstract：:The repeated, intermittent use of cocaine and other drugs of abuse produces profound and often long-lasting alterations in behavior and brain chemistry. It has been suggested that these consequences of drug use play a critical role in drug craving and relapse to addiction. This article reviews the effects of psychosti...

journal_title：Annals of the New York Academy of Sciences

authors： Shippenberg TS,Chefer VI,Zapata A,Heidbreder CA

更新日期：2001-06-01 00:00:00

abstract：:The Balb/c mice were infected with Coxiella burnetii and samples of blood and major organs from the infected mice were collected on days 1 to 14 after infection. The DNAs extracted from the samples were detected by a developed real-time quantitative PCR specific for C. burnetii and high loads of C. burnetii were found...

journal_title：Annals of the New York Academy of Sciences

authors： Zhang J,Wen B,Chen M,Zhang J,Niu D

更新日期：2005-12-01 00:00:00

abstract：:In this review, we discuss how neuropsychological impairments in visual selection can inform us about how selection normally operates. Using neuroanatomical and behavioral evidence on the disorders of neglect, extinction, and simultanagnosia, we propose functional and anatomical links between different aspects of visu...

journal_title：Annals of the New York Academy of Sciences

authors： Riddoch MJ,Chechlacz M,Mevorach C,Mavritsaki E,Allen H,Humphreys GW

更新日期：2010-03-01 00:00:00

abstract：:The alpha-ketoglutarate dehydrogenase complex (KGDHC) is an important mitochondrial constituent, and deficiency of KGDHC is associated with a number of neurological disorders. KGDHC is composed of three proteins, each encoded on a different and well-characterized gene. The sequences of the human proteins are known. Th...

journal_title：Annals of the New York Academy of Sciences

authors： Sheu KF,Blass JP

更新日期：1999-01-01 00:00:00

abstract：:Entomopathogenic fungi are promising alternatives to chemical acaricides in controlling tick populations; however, biological formulations are required to improve conidial performance of these pathogens in the field. This study evaluated the effect of in vitro treatment of Rhipicephalus sanguineus with conidial formul...

journal_title：Annals of the New York Academy of Sciences

authors： Reis RC,Fernandes EK,Bittencourt VR

更新日期：2008-12-01 00:00:00

abstract：:Our tumor necrosis factor-alpha (TNF-alpha) analog LK-805 (E107K) exhibited twofold higher specific cytotoxicity on the mouse fibroblast L-929 cell line than its native counterpart. In addition, significantly lowered systemic toxicity was observed in tumor-bearing mouse models treated with this analog. Due to a charge...

journal_title：Annals of the New York Academy of Sciences

authors： Menart V,Fonda I,Kenig M,Porekar VG

更新日期：2002-11-01 00:00:00

abstract：:Considerable clinical and experimental evidence indicates that loss of vestibular function results in cognitive deficits, especially deficits in spatial memory. These studies demonstrate the importance of balance for the most fundamental of cognitive processes and suggest that information about head acceleration and o...

journal_title：Annals of the New York Academy of Sciences

authors： Smith PF,Brandt T,Strupp M,Darlington CL,Zheng Y

更新日期：2009-05-01 00:00:00

abstract：:Deregulation of signaling pathways is a common feature observed in human cancers and other diseases. Therefore, there is a strong need for compounds that are able to modulate or inactivate upregulated signaling events. Natural compounds extracted from plants have long been used and still present a dynamic domain in th...

journal_title：Annals of the New York Academy of Sciences

authors： Blasius R,Dicato M,Diederich M

更新日期：2007-01-01 00:00:00