The role of NFAT in osteoclast formation.

abstract：:This paper is a progress report on our present understanding of iron nutrition in man, particularly in developing countries. We will be concerned with the quantitative aspects of iron balance and in particular with the availability of dietary iron, the recognition of iron deficiency and its prevalence, the effects of ...

journal_title：Annals of the New York Academy of Sciences

authors： Finch CA

更新日期：1977-11-30 00:00:00

abstract：:Cancer chemoprevention entails the ingestion of dietary or pharmaceutical agents that can prevent, delay, or reverse the process of carcinogenesis. With support provided by the National Cancer Institute, we have been actively engaged in the systematic discovery and characterization of natural chemopreventive agents. T...

journal_title：Annals of the New York Academy of Sciences

authors： Pezzuto JM

更新日期：2011-01-01 00:00:00

abstract：:This paper presents a video-based eye-tracking method, ideally deployed via a mobile device or laptop-based webcam, as a tool for measuring brain function. Eye movements and pupillary motility are tightly regulated by brain circuits, are subtly perturbed by many disease states, and are measurable using video-based met...

journal_title：Annals of the New York Academy of Sciences

authors： Adhikari S,Stark DE

更新日期：2017-01-01 00:00:00

abstract：:The following study describes the basic demography of colorectal cancer patients and characteristics of the disease seen at a regional tertiary care cancer hospital. The study highlights the influence of gender and age on the occurrence of this malignancy in patients in Pakistan. In general, this population shares man...

journal_title：Annals of the New York Academy of Sciences

authors： Anwar N,Badar F,Yusuf MA

更新日期：2008-09-01 00:00:00

abstract：:Local activation of macrophages may play an important role in the immune process of pulmonary infections and in the inflammatory response of lung allograft rejection. To document macrophage activation within human lung allografts displaying various complications, we have investigated ICAM-1 expression in freshly isola...

journal_title：Annals of the New York Academy of Sciences

authors： Fattal-German M,Le Roy Ladurie F,Lecerf F,Berrih-Aknin S

更新日期：1996-10-31 00:00:00

abstract：:Achalasia is a primary motility disorder of the esophagus, and while there are several treatment options, there is no consensus regarding them. When therapeutic intervention for achalasia fails, a careful evaluation of the cause of the persistent or recurrent symptoms using upper endoscopy, esophageal manometry, and c...

journal_title：Annals of the New York Academy of Sciences

authors： Felix VN,Murayama KM,Bonavina L,Park MI

更新日期：2020-12-01 00:00:00

abstract：:Anatomic and electrophysiologic studies have provided evidence that CRF meets some of the criteria as a neurotransmitter in the noradrenergic nucleus, the locus coeruleus (LC), although some of the criteria have yet to be satisfied. Thus, immunohistochemical findings suggest that CRF innervates the LC, but this must b...

journal_title：Annals of the New York Academy of Sciences

authors： Valentino RJ,Foote SL,Page ME

更新日期：1993-10-29 00:00:00

abstract：:Alterations in brain distribution of 11C-MAP, 14C-MAP, and 123I-IMP in MAP- and cocaine-sensitized animals were examined to investigate the mechanism involved in increased dopaminergic transmission and behavioral sensitization. First, a significant increase in 11C-MAP radioactivity in the striatum and hypothalamus was...

journal_title：Annals of the New York Academy of Sciences

authors： Numachi Y,Yoshida S,Inosaka T,Sato M,Mizugaki M,Kimura K,Hishinuma T

更新日期：1992-06-28 00:00:00

abstract：:The song system of oscine birds has become a versatile model system that is used to study diverse problems in neurobiology. Because the song system is often studied with the intention of applying the results to mammalian systems, it is important to place song system brain nuclei in a broader context and to understand ...

journal_title：Annals of the New York Academy of Sciences

authors： Farries MA

更新日期：2004-06-01 00:00:00

abstract：:Anaplasma phagocytophilum (A. phagocytophilum, formerly Ehrlichia phagocytophila) is a tick-borne pathogen responsible for tick-borne fever in ruminants, equine granulocytic ehrlichiosis (EGE) in horses, canine granulocytic ehrlichiosis (CGE) in dogs, and for human granulocytic ehrlichiosis (HGE). Human cases have bee...

journal_title：Annals of the New York Academy of Sciences

authors： Alberti A,Sparagano OA

更新日期：2006-10-01 00:00:00

abstract：:The pregnant uterus is unique because of the dramatic functional changes that occur in the peripartum period. To promote the concept that we have a relatively poor understanding of the physiology of parturition, we will posit 10 facts that are so obvious and so clearly accepted as facts that they probably are not even...

journal_title：Annals of the New York Academy of Sciences

authors： Young RC

更新日期：2007-04-01 00:00:00

abstract：:We have defined three sets of HLA-DR3(+) haplotypes that provide maximum risk of type 1 disease development in Indians: (1) a diverse array of B8-DR3 haplotypes, (2) A33-B58-DR3 haplotype, and (3) A2-B50-DR3 occurring most predominantly in this population. Further analysis has revealed extensive diversity in B8-DR3 ha...

journal_title：Annals of the New York Academy of Sciences

authors： Kumar N,Kaur G,Tandon N,Kanga U,Mehra NK

更新日期：2013-04-01 00:00:00

abstract：:In plants, the photons of light are absorbed at the level of the photosystems in the chloroplasts. The functioning of the photosynthetic electron transfer chain linked to this process is required to generate NADPH and ATP. In addition, the light signal promotes a regulatory cascade, situated in the stroma, that involv...

journal_title：Annals of the New York Academy of Sciences

authors： Jacquot JP,Rouhier N,Gelhaye E

更新日期：2002-11-01 00:00:00

abstract：:The nonpregnant uterus shows uterine activity throughout the menstrual cycle. This uterine activity was detected both by single strep tissue and by using intrauterine pressure recordings in vitro and in vivo. Today, ultrasound has made it possible to study this activity with a noninvasive approach and to assess uterin...

journal_title：Annals of the New York Academy of Sciences

authors： Bulletti C,DE Ziegler D,Setti PL,Cicinelli E,Polli V,Flamigni C

更新日期：2004-12-01 00:00:00

abstract：:Bacterial protein, staphylocoagulase, binds stoichiometrically to human prothrombin resulting in a coagulant complex, staphylothrombin. The enzymatic properties of staphylothrombin differ from those of alpha-thrombin in their substrate specificities toward natural and synthetic substrates, in addition to their interac...

journal_title：Annals of the New York Academy of Sciences

authors： Kawabata S,Morita T,Miyata T,Kaida S,Igarashi H,Iwanaga S

更新日期：1986-01-01 00:00:00

abstract：:Type 1 diabetes (T1D) is a multifactorial disease characterized by the infiltration and subsequent destruction of the pancreatic insulin-producing beta cells by autoreactive T cells. CD8(+) T cells play an essential role in this beta cell destruction. However, little is known about the target antigens of CD8(+) T cell...

journal_title：Annals of the New York Academy of Sciences

authors： Unger WW,Pinkse GG,Mulder-van der Kracht S,van der Slik AR,Kester MG,Ossendorp F,Drijfhout JW,Serreze DV,Roep BO

更新日期：2007-04-01 00:00:00

abstract：:In amphibians, alpha-MSH secreted by the pars intermedia of the pituitary plays a pivotal role in the process of skin color adaptation. Reciprocally, the skin of amphibians contains a number of regulatory peptides, some of which have been found to regulate the activity of pituitary melanotrope cells. In particular, th...

journal_title：Annals of the New York Academy of Sciences

authors： Vaudry H,Chartrel N,Desrues L,Galas L,Kikuyama S,Mor A,Nicolas P,Tonon MC

更新日期：1999-10-20 00:00:00

abstract：:Growing evidence from clinical and epidemiological studies points to a synchronized increase in the incidence of male reproductive problems, such as genital abnormalities, testicular cancer, reduced semen quality, and subfertility. Together these male reproductive problems may reflect the existence of one common entit...

journal_title：Annals of the New York Academy of Sciences

authors： Boisen KA,Main KM,Rajpert-De Meyts E,Skakkebaek NE

更新日期：2001-12-01 00:00:00

abstract：:[(18) F]Fluorodeoxyglucose (FDG) is a tracer for glucose metabolism. Its distribution is not specific to cancer cells but is also observed in inflammatory tissue, including macrophages, capillaries, and fibroblasts. Rheumatoid arthritis (RA) is a systemic, chronic inflammation of the joints resulting in synovitis. The...

journal_title：Annals of the New York Academy of Sciences

authors： Kubota K,Ito K,Morooka M,Minamimoto R,Miyata Y,Yamashita H,Takahashi Y,Mimori A

更新日期：2011-06-01 00:00:00

abstract：:Jackson's Personality Research Form E (PRF) was administered to a large, heterogeneous group of adult inpatients with diagnoses of alcohol and/or drug dependence. Cluster analysis of PRF factor scores yielded five distinct patient subtypes: hostile-dependent, cooperative-nonreflective, socially uninvolved, impulsive-u...

journal_title：Annals of the New York Academy of Sciences

authors： Allen JP,Fertig JB,Mattson ME

更新日期：1994-02-28 00:00:00

abstract：:Differentiation of specific epithelial cell lineages during development, as well as epithelial plasticity in response to heterologous cell-to-cell cross talk during adult life, accounts for the large variety of functions which are performed by the mucosal surfaces found in the human body. Among its functions, the dige...

journal_title：Annals of the New York Academy of Sciences

authors： Hamzaoui N,Pringault E

更新日期：1998-11-17 00:00:00

abstract：:Adrenocortical androgens, including dehydroepiandrosterone (DHEA), are produced in the inner zone of the adrenal cortex that is in direct contact with the neural crest-derived catecholamine-producing chromaffin cells. DHEA has recently been identified as a crucial regulator of neuronal stem cell proliferation. Thus, D...

journal_title：Annals of the New York Academy of Sciences

authors： Ziegler CG,Sicard F,Sperber S,Ehrhart-Bornstein M,Bornstein SR,Krug AW

更新日期：2006-08-01 00:00:00

abstract：:Megadose haploidentical transplants, mismatched at three HLA loci, engraft rapidly and durably without induction of graft-versus-host disease (GVHD). In vitro studies suggest that veto cells, contained in the population of hematopoietic progenitors, facilitate this favorable outcome. Cytotoxic T cells, not reactive ag...

journal_title：Annals of the New York Academy of Sciences

authors： Reisner Y

更新日期：2001-06-01 00:00:00

abstract：:We report a case of latent autoimmune diabetes in adults (LADA), also known as slowly progressive type 1 diabetes (SPT1D), followed up for changes, including reactivity to the GAD65 antibody epitope for the 9-year period from impaired glucose tolerance (IGT) to the insulin-dependent stage (IDDM). This 69-year-old male...

journal_title：Annals of the New York Academy of Sciences

authors： Maruyama T,Koyama A,Hampe CS

更新日期：2008-12-01 00:00:00

abstract：:Over seventy percent of unexpected infant deaths are registered as SIDS. Over 85,000 infants have been screened at birth and one month of age for risk of unexpected death using the Sheffield Score system. Scores range from below 400 to over 800 points. Infants with scores over 800 are at more than 16 times greater ris...

journal_title：Annals of the New York Academy of Sciences

authors： Carpenter RG,Gardner A,Harris J,Judd M,Lewry J,Maddock CR,Powell J,Taylor EM

更新日期：1988-01-01 00:00:00

abstract：:Posttraumatic stress disorder (PTSD) is typically accompanied by both acute and chronic alterations in the stress response. These alterations have mostly been described in individuals under baseline conditions, but studies have also used a challenge model to assess the role of the hypothalamic-pituitary-adrenal (HPA) ...

journal_title：Annals of the New York Academy of Sciences

authors： Vermetten E,Vythilingam M,Schmahl C,DE Kloet C,Southwick SM,Charney DS,Bremner JD

更新日期：2006-07-01 00:00:00

abstract：:Accelerated atherosclerosis occurs in patients with type III hyperlipoproteinemia and familial hypercholesterolemia. These genetic disorders focus attention on specific types of lipoproteins as being responsible for the development of accelerated coronary artery heart disease. The accumulation of chylomicron remnants ...

journal_title：Annals of the New York Academy of Sciences

authors： Weisgraber KH,Innerarity TL,Rall SC Jr,Mahley RW

更新日期：1990-01-01 00:00:00

abstract：:The entorhinal cortex, subiculum, and hippocampus have been regions of great interest in both clinical and neuropathological investigations of schizophrenia. Postmortem studies have identified numerous abnormalities, although many remain controversial or unconfirmed. Among the cellular and molecular neuropathological ...

journal_title：Annals of the New York Academy of Sciences

authors： Arnold SE

更新日期：2000-06-01 00:00:00

abstract：:Functional decline of tissues in aged animals is a result of cellular aging. Though any process of somatic cell aging basically depends on genomic instructions, phenotypes of aged cells are expressed in a given internal environment of each cell type that was made with translated proteins and post-translationally modif...

journal_title：Annals of the New York Academy of Sciences

authors： Toda T

更新日期：2001-04-01 00:00:00

abstract：:The effect of DHEA administration on the age-associated decline in immunity against influenza vaccine was studied. Increased humoral response was observed in 16- and 24-month-old mice immunized by live A/PR/8/34 (H1N1) influenza virus following DHEA treatment (a single injection adjacent to immunization). Furthermore,...

journal_title：Annals of the New York Academy of Sciences

authors： Danenberg HD,Ben-Yehuda A,Zakay-Rones Z,Friedman G

更新日期：1995-12-29 00:00:00