Regulation of osteoclast differentiation.

abstract：:This article aims to estimate the prevalence of SOX13 antibodies in Swedish patients with type 1 diabetes and healthy controls. The patients (n = 102; median age 35 years [range, 9-89]) were newly diagnosed with type 1 diabetes in a defined area in southern Sweden during 1995-1998. Islet cell antibodies (ICA) were ana...

journal_title：Annals of the New York Academy of Sciences

authors： Törn C,Shtauvere-Brameus A,Sanjeevi CB,Landin-Olsson M

更新日期：2002-04-01 00:00:00

abstract：:Clostridium difficile infection, also known as C. difficile-associated diarrhea (CDAD), is the most common cause of nosocomial diarrhea, typically initiated by the use of broad-spectrum antibiotics that disrupt gut flora, thereby allowing C. difficile to proliferate. It is an increasing cause of morbidity and mortalit...

journal_title：Annals of the New York Academy of Sciences

authors： Sears P,Ichikawa Y,Ruiz N,Gorbach S

更新日期：2013-07-01 00:00:00

abstract：:The oxidative modification of proteins by reactive species, especially reactive oxygen species, is implicated in the etiology or progression of a panoply of disorders and diseases. These reactive species form through a large number of physiological and non-physiological reactions. An increase in the rate of their prod...

journal_title：Annals of the New York Academy of Sciences

authors： Stadtman ER,Levine RL

更新日期：2000-01-01 00:00:00

abstract：:Our earlier studies of translation have led us to a specific numeric coding of nucleotides (A = 0, C = 1, G = 2, and U = 3)--that is, a quaternary numeric system; to ordering of digrams and codons (read right to left: .yx and Z.yx) as ordinal numbers from 000 to 111; and to seek hypothetic transformation of mRNA to 20...

journal_title：Annals of the New York Academy of Sciences

authors： Damjanović ZM,Rakocević MM

更新日期：2005-06-01 00:00:00

abstract：:The Br-type neuron of the snail Helix pomatia, involved in neuronal regulation of various homeostatic and adaptive mechanisms, represents an interesting model for studying effects of temperature change on neuronal activity of poikilotherms. Acetylcholine induces a transient, inward dose-dependent current in the identi...

journal_title：Annals of the New York Academy of Sciences

authors： Nedeljković M,Kartelija G,Radenović L

更新日期：2005-06-01 00:00:00

abstract：:The fate of alpha-hemoglobin chains and the cause of membrane protein defects in thalassemic erythrocytes have been studied in: (1) human beta-thalassemia syndromes, (2) mouse beta-thalassemia, and (3) normal human erythrocytes loaded with purified alpha-hemoglobin chains. The similarity and differences observed in th...

journal_title：Annals of the New York Academy of Sciences

authors： Rouyer-Fessard P,Scott MD,Leroy-Viard K,Garel MC,Bachir D,Galacteros F,Beuzard Y

更新日期：1990-01-01 00:00:00

abstract：:Three distinct anion exchangers are described that directly or indirectly mediate Cl- transport across the luminal membrane of the proximal tubule cell. Studies on the intact proximal tubule indicate that the Cl(-)-formate exchanger is a major mechanism for Cl- transport under physiologic conditions. As just discussed...

journal_title：Annals of the New York Academy of Sciences

authors： Aronson PS,Kuo SM

更新日期：1989-01-01 00:00:00

abstract：:To investigate the role of poliovirus (PV) infection in the development of the post-polio syndrome (PPS), we studied the serum, spinal fluid, peripheral blood lymphocytes, and muscle from 47 patients with PPS. We found high titers of IgM PV antibodies (up to 1:250) in the serum of 6 patients, compared to very low tite...

journal_title：Annals of the New York Academy of Sciences

authors： Leon-Monzon ME,Dalakas MC

更新日期：1995-05-25 00:00:00

abstract：:Insulin-related peptides (IRPs) from ganglions of mollusk, Anodonta cygnea, were purified and characterized (IRP1-IRP13) using insulin and insulin-like growth factor-I (IGF-I) radioreceptor test systems. The IRPs were able to bind to insulin and IGF-I receptors. Dose-dependent curve slopes indicated that most IRPs bin...

journal_title：Annals of the New York Academy of Sciences

authors： Shipilov VN,Shpakov AO,Rusakov YI

更新日期：2005-04-01 00:00:00

abstract：:Primary hyperparathyroidism (PHPT) results from excessive secretion of parathyroid hormone (PTH), and catabolic and anabolic effects of PTH on bone may lead to overall deleterious effects on skeleton. The aim of this study was to analyze the changes in lumbar spine bone mineral density (BMD) in patients with PHPT who ...

journal_title：Annals of the New York Academy of Sciences

authors： Lumachi F,Camozzi V,Ermani M,Nardi A,Luisetto G

更新日期：2007-11-01 00:00:00

abstract：:Epithelial cell sheet formation is central to many aspects of vertebrate development and function. For example, it is a major principle of differentiation in embryogenesis and regeneration, enables the compartmentalization of tissues, and is the basis for the maintenance of homeostasis throughout the body. A key chara...

journal_title：Annals of the New York Academy of Sciences

authors： Yano T,Kanoh H,Tamura A,Tsukita S

更新日期：2017-10-01 00:00:00

abstract：:During the past decade, a considerable body of evidence has emerged showing that circumstances during the fetal period may have lifelong programming effects on different body functions with a considerable impact on disease susceptibility. The purpose of this article is to provide a synopsis of these findings and their...

journal_title：Annals of the New York Academy of Sciences

authors： Kajantie E

更新日期：2006-11-01 00:00:00

abstract：:The Buddhist view of the origin of the universe is discussed. One of the basic tenets of Buddhism is the concept of interdependence which says that all things exist only in relationship to others, and that nothing can have an independent and autonomous existence. The world is a vast flow of events that are linked toge...

journal_title：Annals of the New York Academy of Sciences

authors： Thuan TX

更新日期：2001-12-01 00:00:00

abstract：:Cognitive enhancement, the amplification or extension of core capacities of the mind, has become a major topic in bioethics. But cognitive enhancement is a prime example of a converging technology where individual disciplines merge and issues transcend particular local discourses. This article reviews currently availa...

journal_title：Annals of the New York Academy of Sciences

authors： Sandberg A,Bostrom N

更新日期：2006-12-01 00:00:00

abstract：:Cystic fibrosis (CF) is associated with abnormal lipid metabolism, intense respiratory tract (RT) infection, and inflammation, eventually resulting in lung tissue destruction and respiratory failure. The CF RT inflammatory milieu, as reflected by airway secretions, includes a complex array of inflammatory mediators, b...

journal_title：Annals of the New York Academy of Sciences

authors： Eiserich JP,Yang J,Morrissey BM,Hammock BD,Cross CE

更新日期：2012-07-01 00:00:00

abstract：:The hypothalamus is one of the master regulators of various physiological processes, including energy balance and nutrient metabolism. These regulatory functions are mediated by discrete hypothalamic regions that integrate metabolic sensing with neuroendocrine and neural controls of systemic physiology. Neurons and no...

journal_title：Annals of the New York Academy of Sciences

authors： Cai D,Liu T

更新日期：2011-12-01 00:00:00

abstract：:Emerging infectious diseases are of international concern because of the potential for, and impact of, pandemics; however, they are difficult to predict. To identify the drivers of disease emergence, we analyzed infectious disease threat events (IDTEs) detected through epidemic intelligence collected at the European C...

journal_title：Annals of the New York Academy of Sciences

authors： Semenza JC,Rocklöv J,Penttinen P,Lindgren E

更新日期：2016-10-01 00:00:00

abstract：:Auditory imagery can represent many aspects of music, such as the starting pitches of a tune or the instrument that typically plays it. In this paper, I concentrate on more dynamic, or time-sensitive aspects of musical imagery, as demonstrated in two recently published studies. The first was a behavioral study that ex...

journal_title：Annals of the New York Academy of Sciences

authors： Halpern AR

更新日期：2012-04-01 00:00:00

abstract：:Carbon nanotubes are considered to be one of the novel most attractive materials in nanotechnology. Because of their multiple industrial and biomedical applications, thorough studies on their toxicity and biocompatibility become a priority in order to prevent possible health risks. In this study the effects of multiwa...

journal_title：Annals of the New York Academy of Sciences

authors： De Nicola M,Nuccitelli S,Gattia DM,Traversa E,Magrini A,Bergamaschi A,Ghibelli L

更新日期：2009-08-01 00:00:00

abstract：:The trailblazing research on sleep mechanisms and petit mal epilepsy, conducted during the period from 1940 through 1970, illuminated the brain substrate for normal consciousness and attention, as well as their disorders. This research helped inform and structure our neuropsychologically based model of the "elements" ...

journal_title：Annals of the New York Academy of Sciences

authors： Mirsky AF,Duncan CC

更新日期：2001-06-01 00:00:00

abstract：:Nonpathogenic enteric bacterial species initiate and perpetuate experimental colitis in interleukin-10 geneeficient mice (IL-10(-/-)). Bacteria-specific effects on the epithelium are difficult to distinguish because of the complex nature of the gut microflora. We showed that IL-10(-/-) mice compared to wild-type mice ...

journal_title：Annals of the New York Academy of Sciences

authors： Ruiz PA,Shkoda A,Kim SC,Sartor RB,Haller D

更新日期：2006-08-01 00:00:00

abstract：:Human diploid fibroblasts (WI38) were inoculated into Rose multipurpose culture chambers, using a high population density to develop confluency. After 24 hours, cells from a 1 mm swath were scraped from the center of the chamber. This cleared path was positioned to permit an unobstructed transmission of a 0.9 X 20 mm ...

journal_title：Annals of the New York Academy of Sciences

authors： Rounds DE,Olson RS,Booher J

更新日期：1976-01-30 00:00:00

abstract：:Management of gastroesophageal junction (GEJ) adenocarcinoma is a controversial topic. The rising incidence of this cancer requires a clear consensus to ensure proper management. Application of oncological principles for tumors of the esophagus or stomach is not possible because of comparative differences in the biolo...

journal_title：Annals of the New York Academy of Sciences

authors： Chevallay M,Bollschweiler E,Chandramohan SM,Schmidt T,Koch O,Demanzoni G,Mönig S,Allum W

更新日期：2018-12-01 00:00:00

abstract：:The results reviewed here demonstrate that vestibulospinal and vestibulo-ocular interneurons in the chicken embryo are organized into coherent clusters, each of which occupies a unique spatial domain and has a characteristic axon trajectory. Moreover, the vestibulo-ocular clusters have specific termination patterns in...

journal_title：Annals of the New York Academy of Sciences

authors： Glover JC

更新日期：1996-06-19 00:00:00

abstract：:The role of acid-base interactions during coordinated acinar and duct cell secretion in the exocrine pancreas is described. The sequence of acid-base events may be summarized as follows: (1) Sorting of secretory proteins and membrane components into the regulated secretory pathway of pancreatic acinar cells is trigger...

journal_title：Annals of the New York Academy of Sciences

authors： Freedman SD,Scheele GA

更新日期：1994-03-23 00:00:00

abstract：:Effects of in situ extraction, fungal elicitation, a permeabilizing agent, and the oxygen transfer rate on shikonin production in transformed suspension and hairy root cultures of Lithospermum erythrorhizon were studied. Shikonin production with in situ extraction in transformed cell and hairy root cultures by n-hexad...

journal_title：Annals of the New York Academy of Sciences

authors： Sim SJ,Kim DJ,Chang HN

更新日期：1994-11-30 00:00:00

abstract：:Saliva is an underused fluid with considerable promise for biomedical testing. Its potential is particularly great for monitoring small-molecule analytes since these are often present in saliva at concentrations that correlate well with their free levels in blood. We describe the development of a prototype diagnostic ...

journal_title：Annals of the New York Academy of Sciences

authors： Fu E,Chinowsky T,Nelson K,Johnston K,Edwards T,Helton K,Grow M,Miller JW,Yager P

更新日期：2007-03-01 00:00:00

abstract：:Disorders of sexual differentiation (DSDs) presenting during adolescence are discussed, and molecular explanations are given for some. DSD conditions are often discovered during early adolescence, an age well known to predispose to high risk for adjustment problems. Presentation may be with lack of or minimal pubertal...

journal_title：Annals of the New York Academy of Sciences

authors： Lee PA,Houk CP

更新日期：2008-01-01 00:00:00

abstract：:The serologic and molecular characterization of four monoclonal antibodies to human gastric cancer cells and to CEA were described and the immunohistologic patterns of reactions with freshly obtained gastrointestinal tissues were examined. Monoclonal antibody YK004, which was secreted by the hybridoma constructed with...

journal_title：Annals of the New York Academy of Sciences

authors： Yachi A,Imai K,Moriya Y,Fujita H,Tanda M,Nishi S,Kawaharada M

更新日期：1983-01-01 00:00:00

abstract：:Organophosphorus pesticides (OPs) and nerve agents (NAs) are highly toxic chemicals that pose a significant threat to human health worldwide. These compounds induce status epilepticus (SE) by irreversibly blocking the ability of acetylcholinesterase to break down acetylcholine at neural synapses. Animal models of orga...

journal_title：Annals of the New York Academy of Sciences

authors： McCarren HS,McDonough JH Jr

更新日期：2016-06-01 00:00:00