Abstract:
:The SERMs currently in clinical practice or in late stages of clinical development have been studied primarily for their effects on the breast, cardiovascular, bone, and reproductive systems. The effect of SERMs on the hypothalamic-pituitary-gonadal (HPG) axis has not been the primary focus of the studies conducted thus far. However the effect of SERMs on the HPG axis and the associated regulation of endocrine parameters may play an important role in their overall clinical profile. In this review the effects of selected SERMs on the HPG axis in premenopausal women, postmenopausal women, and men are summarized.
journal_name
Ann N Y Acad Scijournal_title
Annals of the New York Academy of Sciencesauthors
Plouffe L Jr,Siddhanti Sdoi
10.1111/j.1749-6632.2001.tb04029.xsubject
Has Abstractpub_date
2001-12-01 00:00:00pages
251-8eissn
0077-8923issn
1749-6632journal_volume
949pub_type
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更新日期:2003-04-01 00:00:00
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