Cyclic nucleotides in the rat neostriatum: push-pull perfusion studies.

abstract：:This study examined the hypothesis that the subfornical organ (SFO), a circumventricular organ with both osmosensitive elements and dipsogenic receptors for circulating angiotensin (ANG) II, is important for the water drinking response that follows an intragastric (ig) load of hypertonic NaCl. A 2-ml saline load was a...

journal_title：Brain research

authors： Starbuck EM,Fitts DA

更新日期：1998-06-08 00:00:00

abstract：:Research supports the effectiveness of acupuncture for conditions such as chronic low back and knee pain. In a five-patient pilot study the modality also improved the symptoms of chemotherapy-induced neuropathic pain. Using an established rat model of paclitaxel-induced peripheral neuropathy, we evaluated the effect o...

journal_title：Brain research

authors： Meng X,Zhang Y,Li A,Xin J,Lao L,Ren K,Berman BM,Tan M,Zhang RX

更新日期：2011-09-26 00:00:00

abstract：:We used rabbit antisera against manganese (Mn)-superoxide dismutase for immunohistochemical studies of localization in the rat neostriatum. Immunostaining was intense in large-sized neurons and several medium-sized neurons, but it was moderate to weak in other cells. Double immunostaining with monoclonal antibody to c...

journal_title：Brain research

authors： Inagaki S,Suzuki K,Taniguchi N,Takagi H

更新日期：1991-05-17 00:00:00

abstract：:To elucidate the generation mechanisms of interictal spikes we analyzed the electrical events in the different layers of the rabbit's neocortex after application of penicillin to distinct cortical layers. Field potentials (FP) recorded simultaneously from all layers with a 16-fold micro-electrode-assembly were subject...

journal_title：Brain research

authors： Pockberger H,Rappelsberger P,Petsche H

更新日期：1984-09-10 00:00:00

abstract：:Ginseng is one of most extensively used traditional oriental medicines worldwide with beneficial efficacy on cognitive function disorders. Pharmacological researches on its active ingredient--ginsenoside Rg1 revealed that it can improve learning and memory potentially via modulating neurotransmission in the central ne...

journal_title：Brain research

authors： Liu ZJ,Zhao M,Zhang Y,Xue JF,Chen NH

更新日期：2010-05-28 00:00:00

abstract：:Nerve-evoked muscle depolarisation plays an important role in the downregulation of extrasynaptic AChRs which accompanies the increase in synaptic AChR expression at the neuromuscular junction during embryonic development. However, additional mechanisms may be involved in the AChR downregulation. This study provides e...

journal_title：Brain research

authors： Montgomery JM,Fleming JS,Mills RG

更新日期：1999-02-13 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by upper and lower motor neuron death with ascending paralysis leading to death. In a transgenic mouse model of ALS (SOD1-G93A) weakness appears at 3 months of age, and because of progressive paralysis leads to death by 5 months. Cyclospo...

journal_title：Brain research

authors： Keep M,Elmér E,Fong KS,Csiszar K

更新日期：2001-03-16 00:00:00

abstract：:The dorsolateral quadrant of the lateral septal nucleus receives projections from both the ipsilateral and the contralateral fimbria. In the adult rat the effect of fimbrial lesions on synapse formation has been studied by a quantitative electron microscopic analysis of the various types of synapses present, using ele...

journal_title：Brain research

authors： Field PM,Coldham DE,Raisman G

更新日期：1980-05-05 00:00:00

abstract：:The first phase of this study involves injecting a different fluorescent retrograde axonal tracer into the subthalamic nucleus, the substantia nigra, and the mesopontine tegmentum. Multiple labeled cells are found within the caudal third of the globus pallidus. The entopeduncular nucleus and adjacent basal forebrain s...

journal_title：Brain research

authors： Schmued L,Phermsangngam P,Lee H,Thio S,Chen E,Truong P,Colton E,Fallon J

更新日期：1989-05-15 00:00:00

abstract：:Nitric oxide (NO) production in the sensory neurons of the rad nodose ganglion was studied by examining the distribuiotn of NO synthase (NOS) by use of NADPH diaphorase (NADPHD) histochemistry and immunohistochemistry ofr the presence of isoformes of NOS: neuronal (nNOS), endothelial (eNOS) and the inducible isoform (...

journal_title：Brain research

authors： Yamamoto Y,Henrich M,Snipes RL,Kummer W

更新日期：2003-01-24 00:00:00

abstract：:Immunohistochemical staining with mouse monoclonal antibody R24 recognizing the ganglioside GD3 was used to study the distribution of GD3 in the human brain. Positive staining was primarily found in the surrounding neuropil of many neuronal groups in the brainstem and spinal cord, cerebellum, retina and dentate gyrus ...

journal_title：Brain research

authors： Graus F,Cordon-Cardo C,Houghton AN,Melamed MR,Old LJ

更新日期：1984-12-17 00:00:00

abstract：:Pregnenolone sulfate (PS) is an endogenous neurosteroid known to antagonize GABA(A) receptor-mediated inhibitory responses and potentiate NMDA receptor-mediated excitatory responses in vitro. To assess the actions of the steroid as a modulator of seizure susceptibility in vivo, PS (30-300 nmol) was administered intrac...

journal_title：Brain research

authors： Kokate TG,Juhng KN,Kirkby RD,Llamas J,Yamaguchi S,Rogawski MA

更新日期：1999-06-12 00:00:00

abstract：:The ability of crude cerebrum supernatant to stabilize, at a low temperature, cold-labile microtubules purified from beef brain was studied during development in the rat. The cold-stabilizing activity of the supernatant was low during the first postnatal week, rose significantly during the second postnatal week, and t...

journal_title：Brain research

authors： Faivre-Sarrailh C,Rabié A

更新日期：1988-08-01 00:00:00

abstract：:The type and cell size of parvalbumin-immunoreactive (PV-Ir) neurones were examined in 14 postmortem brains from elderly control and Alzheimer-type dementia (ATD) patients with the aid of an image analyser. Morphological features of PV-Ir neurones suggested the existence of PV in the non-pyramidal interneurones in the...

journal_title：Brain research

authors： Arai H,Emson PC,Mountjoy CQ,Carassco LH,Heizmann CW

更新日期：1987-08-18 00:00:00

abstract：:Parvalbumin (PV)-immunoreactive neurons in rat neostriatum were studied under light and electron microscopes. A small number of neurons in the striatum were immunoreactive for PV (a Ca-binding protein). Most of them were also strongly immunoreactive for glutamate decarboxylase but were negative for NADPH-diaphorase ac...

journal_title：Brain research

authors： Kita H,Kosaka T,Heizmann CW

更新日期：1990-12-17 00:00:00

abstract：:Senescent (26-28 months) Fischer 344 rats were shown to have a lower density of D2 sites (-36%) without any change in affinity in membranes prepared from homogenized caudate-putamen (CPU), as compared to young adult (5-6 months) rats. In additional rats prepared for quantitative autoradiography of [3H]spiroperidol bin...

journal_title：Brain research

authors： Joyce JN,Loeschen SK,Sapp DW,Marshall JF

更新日期：1986-07-16 00:00:00

abstract：:The effects of subchronic administration of the antidepressant fluoxetine (15 mg/kg i.p., 14 days) on thyroid hormone metabolism were investigated in 11 regions of the CNS and three peripheral tissues in the rat. Fluoxetine significantly enhanced the activity of the 5'II-deiodinase isoenzyme (5'D-II), which catalyzes ...

journal_title：Brain research

authors： Baumgartner A,Dubeyko M,Campos-Barros A,Eravci M,Meinhold H

更新日期：1994-01-28 00:00:00

abstract：:The influence of extracellular sinusoidal electric fields on the amplitude of population spikes evoked by single test pulses in excitatory pathways to CA1 pyramidal neurons was studied in rat hippocampal slices. The fields in the tissue were of the order of EEG gradients. Stimulation at 5 Hz, a frequency representativ...

journal_title：Brain research

authors： Bawin SM,Sheppard AR,Mahoney MD,Adey WR

更新日期：1984-12-10 00:00:00

abstract：:The analysis of the dynamic properties of epileptiform activity in vitro has led to a better understanding of the time course of neural synchronization and seizure states. Nonlinear analysis is thus potentially useful for the prediction of seizure onset. We have used nonlinear analysis methods to investigate the devel...

journal_title：Brain research

authors： Lian J,Shuai J,Hahn P,Durand DM

更新日期：2001-02-02 00:00:00

abstract：:A study was made of the effects of electrochemically stimulating (ECS) and destroying the midbrain dorsal and median raphe nuclei on the estrogen-progesterone- (EP) induced surge of pituitary LH release in ovariectomized rats. ECS and lesions were produced simultaneously with anodal direct current through a chronicall...

journal_title：Brain research

authors： Waloch M,Gilman D,Whitmoyer D,Sawyer CH

更新日期：1981-08-03 00:00:00

abstract：:Low concentrations of dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) enhanced neuronal and glial survival and/or differentiation in dissociated cultures of 14-day mouse embryo brain. Posttrial intracisternal injection into the brains of mice undergoing active avoidance training alleviated amn...

journal_title：Brain research

authors： Roberts E,Bologa L,Flood JF,Smith GE

更新日期：1987-03-17 00:00:00

abstract：:Neurotransmitter effects were studied on in vitro release of immunoreactive somatostatin (SRIF) from slices prepared from several regions of the rat brain: mediobasal hypothalamus (MBH), preoptic anterior hypothalamic area (POA) and amygdaloid complex (AMY). Potassium (K+, 56 mM) stimulated SRIF release in all structu...

journal_title：Brain research

authors： Epelbaum J,Tapia-Arancibia L,Kordon C

更新日期：1981-06-29 00:00:00

abstract：:Somatosensory neurons including nociceptive ones in the medial thalamus have been studied extracellularly, and are classified into three types: nociceptive-specific, wide dynamic range, and tap neurons. However, the morphological characteristics of these three neurons have not yet been clarified. We studied the morpho...

journal_title：Brain research

authors： Sugiyama K,Ryu H,Uemura K

更新日期：1992-07-17 00:00:00

abstract：:The effect of a single subcutaneous (s.c.) injection of the ultrapotent capsaicin analogue resiniferatoxin (RTX) on responses of adult rats to noxious thermal and mechanical stimulation was examined. The effects of RTX treatment on the nociceptive flexor reflex and activity-dependent increase in spinal excitability af...

journal_title：Brain research

authors： Xu XJ,Farkas-Szallasi T,Lundberg JM,Hökfelt T,Wiesenfeld-Hallin Z,Szallasi A

更新日期：1997-03-28 00:00:00

abstract：:Following lesions of the pyramidal tract in hamsters, retrograde changes were studied in the sensorimotor cortex and in the pyramidal tract axons proximal to the lesion, at survival times ranging from 2 weeks to 14 months. Severe cell shrinkage occurred in layer 5 pyramidal neurons as early as 2 weeks, but there was n...

journal_title：Brain research

authors： Kalil K,Schneider GE

更新日期：1975-05-16 00:00:00

abstract：:Afferent pathways innervating the urinary bladder consist of myelinated Adelta- and unmyelinated C-fibers, the neuronal cell bodies of which correspond to medium and small-sized cell populations of dorsal root ganglion (DRG) neurons, respectively. Since hyperpolarization-activated cyclic nucleotide-gated cation (HCN) ...

journal_title：Brain research

authors： Matsuyoshi H,Masuda N,Chancellor MB,Erickson VL,Hirao Y,de Groat WC,Wanaka A,Yoshimura N

更新日期：2006-11-13 00:00:00

abstract：:Perinatal exposure to environmental tobacco smoke (ETS) has adverse effects on neurobehavioral development. In the current study, rats were exposed to ETS during gestation, during the early neonatal period, or both. Brains and hearts were examined for alterations in adenylyl cyclase (AC) activity and for changes in be...

journal_title：Brain research

authors： Slotkin TA,Pinkerton KE,Garofolo MC,Auman JT,McCook EC,Seidler FJ

更新日期：2001-04-13 00:00:00

abstract：:To learn whether there are developmental changes in salt and acid taste responses from the posterior tongue, we recorded from the glossopharyngeal nerve, which innervates taste buds in circumvallate papillae, in sheep fetuses, lambs and adults. Multifiber responses to NH4Cl, KCl, NaCl, LiCl, citric and hydrochloric ac...

journal_title：Brain research

authors： Mistretta CM,Bradley RM

更新日期：1983-12-01 00:00:00

abstract：:Cerebrovascular diseases are currently a major global health problem. Considering the limitations of current therapy, the search for new alternatives for the treatment of these diseases is necessary and, in this context, curcumin, a molecule that has neuroprotective properties already described in the literature. A li...

journal_title：Brain research

authors： Marques MS,Cordeiro MF,Marinho MAG,Vian CO,Vaz GR,Alves BS,Jardim RD,Hort MA,Dora CL,Horn AP

更新日期：2020-11-01 00:00:00

abstract：:The control of hypoglossal motoneurons during sleep is important from a basic science perspective as well as to understand the bases for pharyngeal occlusion which results in the obstructive sleep apnea syndrome. In the present work, we used intracellular recording techniques to determine changes in membrane propertie...

journal_title：Brain research

authors： Fung SJ,Yamuy J,Xi MC,Engelhardt JK,Morales FR,Chase MH

更新日期：2000-12-08 00:00:00