Effects of dehydroepiandrosterone and its sulfate on brain tissue in culture and on memory in mice.

abstract：:We examined the effects of systemic administration of gamma-vinyl gamma-aminobutyric acid (GVG), a gamma-aminobutyric acid (GABA) transaminase inhibitor, on the kindling model of epilepsy in rats. GVG (1200 or 1500 mg/kg) approximately doubled the number of stimulations required for kindling development. GVG also supp...

journal_title：Brain research

authors： Shin C,Rigsbee LC,McNamara JO

更新日期：1986-11-29 00:00:00

abstract：:The study makes an attempt to find out the action of norepinephrine (NE) and phenoxybenzamine (PB), applied at medial preoptic area (mPOA), in altering the sleep-awake responses, in free moving rats, which has not yet been reported. Effects of application of NE during day and PB during night, at mPOA, on sleep-awake r...

journal_title：Brain research

authors： Mohan Kumar V,Datta S,Chhina GS,Gandhi N,Singh B

更新日期：1984-11-26 00:00:00

abstract：:Calretinin and calbindin-D28k are two calcium-binding proteins which are present in separate populations of interneurons in cerebral cortex and hippocampus. To identify these cells with the populations expressing different transmitters, two-colour immunofluorescence was done with antibodies against the calcium-binding...

journal_title：Brain research

authors： Rogers JH

更新日期：1992-07-31 00:00:00

abstract：:Recently the nuclear proto-oncogene c-fos has been shown to be rapidly and transiently expressed following seizures in many types of epilepsies. Until now, immunohistochemical as well as in situ hybridization studies have reported that the dentate gyrus of the hippocampus and most of the cortical areas were invariably...

journal_title：Brain research

authors： Le Gal La Salle G,Naquet R

更新日期：1990-06-04 00:00:00

abstract：:The opioid peptides Leu-enkephalin, Met-enkephalin and D-Ala2-Met-enkephalinamide were injected at various concentrations into the neocortex and hippocampus of rats to examine their effects on EEG activity and DC potentials. All three compounds were found to elicit spreading depression (SD) in both structures. Higher ...

journal_title：Brain research

authors： Sprick U,Oitzl MS,Ornstein K,Huston JP

更新日期：1981-04-06 00:00:00

abstract：:Binding of cyclic AMP to the regulatory subunit of cyclic AMP-dependent protein kinase (PKA) is an essential step in cyclic AMP-mediated intracellular signal transduction. This binding is, however, rapidly inhibited in the acute phase of cerebral ischemia, indicating that the signal transduction via PKA is very vulner...

journal_title：Brain research

authors： Tanaka K,Ito D,Suzuki S,Dembo T,Kosakai A,Fukuuchi Y

更新日期：2002-01-04 00:00:00

abstract：:In order to determine the origin of the catecholamine innervation of the rat piriform cortex (PC), we combined retrograde transport of the B subunit of the cholera toxin (CTb) with tyrosine hydroxylase (TH) immunohistochemistry. A substantial number of CTb retrogradely labeled cells was found in the parabrachial pigme...

journal_title：Brain research

authors： Datiche F,Cattarelli M

更新日期：1996-02-26 00:00:00

abstract：:We measured the uptake of a radiolabeled analogue of glucose ([3H]FDG) into muscles during treadmill walking so as to determine whether sensory deafferentation of a limb affects the muscles' metabolic response to the exercise. The muscles on the deafferented side took up less tracer than those in the intact side with ...

journal_title：Brain research

authors： Eidelberg E,Miller AL

更新日期：1985-02-18 00:00:00

abstract：:Opiates and cannabinoids are among the most widely consumed habit-forming drugs in humans. Several studies have demonstrated the existence of interactions between both kind of drugs in a variety of effects and experimental models. The present study has been focused to determine whether perinatal delta9-tetrahydrocanna...

journal_title：Brain research

authors： Vela G,Martín S,García-Gil L,Crespo JA,Ruiz-Gayo M,Fernández-Ruiz JJ,García-Lecumberri C,Pélaprat D,Fuentes JA,Ramos JA,Ambrosio E

更新日期：1998-10-05 00:00:00

abstract：:This study was designed to describe renal afferent information with respect to its intraspinal projections, convergence with cutaneous inputs, ascending projections, and modulation by descending fiber tracts. Extracellular recordings were made from neurons in the spinal gray while electrically stimulating the renal ne...

journal_title：Brain research

authors： Knuepfer MM,Akeyson EW,Schramm LP

更新日期：1988-04-12 00:00:00

abstract：:The postnatal maturation of the medial preoptic area (MPOA) of male and female rats was studied by means of light and electron microscopy. In Golgi-Kopsch preparations, bi- and multipolar cells were present at birth in both sexes; the perikarya of most of these cells, as seen with the electron microscope, exhibited an...

journal_title：Brain research

authors： Reier PJ,Cullen MJ,Froelich JS,Rothchild I

更新日期：1977-02-25 00:00:00

abstract：:We previously reported that abdominal surgery induces Fos expression in specific hypothalamic and medullary nuclei and also causes gastric stasis. The gastric ileus is reduced by systemic capsaicin and abolished by central injection of corticotropin-releasing factor (CRF) antagonist. We studied the influence of system...

journal_title：Brain research

authors： Bonaz B,Taché Y

更新日期：1997-02-14 00:00:00

abstract：:Dural afferent neurons are implicated in primary headaches including migraine. Although a significant portion of primary afferent neurons innervating the dura are myelinated A-type neurons, previous electrophysiological studies have primarily characterized the functional properties of small-sized C-type sensory neuron...

journal_title：Brain research

authors： Nakamura M,Jang IS

更新日期：2018-10-01 00:00:00

abstract：:Projections from the hypothalamus to cells of origin of the greater petrosal nerve were studied by the HRP and autoradiographic techniques in the rat. After an injection of [3H]amino acids into the hypothalamus and an application of HRP to the greater petrosal nerve, we found that a compact group of HRP-labeled neuron...

journal_title：Brain research

authors： Hosoya Y,Matsushita M,Sugiura Y

更新日期：1984-01-02 00:00:00

abstract：:NO performs a wide array of cell signaling functions. Neuronal NO synthase (nNOS) immunoreactivity and nicotinamide adenine dinucleotide phosphate diaphorase (NDP) activity, a marker of nNOS, were concentrated at adult rat neuromuscular junctions and persisted in denervated muscle indicating the localization of the en...

journal_title：Brain research

authors： Kusner LL,Kaminski HJ

更新日期：1996-08-19 00:00:00

abstract：:The synaptic regulatory mechanism of resting membrane potential of layer III and V pyramidal neurons was analyzed intracellularly in the slice preparation of cat sensorimotor cortex. During the tetanic stimulation of white matter, subthreshold membrane depolarization was induced, and after that, a slowly developing hy...

journal_title：Brain research

authors： Kitagawa H,Nishimura Y,Kumazawa Y,Akamine T,Yamamoto T

更新日期：2000-06-30 00:00:00

abstract：:The action of gamma-aminobutyric acid (GABA) in the supraoptic nucleus was investigated using guinea pig brain slices. GABA produced a membrane depolarization accompanied by a decrease in the input resistance. The action of GABA was concentration-dependent throughout a wide range of concentrations (10(-7)-10(-3) M). I...

journal_title：Brain research

authors： Ogata N

更新日期：1987-02-17 00:00:00

abstract：:An extensive exploration of the discriminating properties of olfactory receptors cells has been conducted in our laboratory through the statistical processing of single cell responses recorded in the frog's olfactory epithelium. Similarities between odorant stimulating properties could be demonstrated by comparing the...

journal_title：Brain research

authors： Sicard G,Holley A

更新日期：1984-02-06 00:00:00

abstract：:Long-term potentiation (LTP) has a memory-like consolidation period during which it becomes progressively stabilized. However, it is unknown how the consolidation is achieved. The present study demonstrates that nicotine reverses stabilized LTP in the hippocampal CA1 region, providing the first evidence that consolida...

journal_title：Brain research

authors： Guan X,Nakauchi S,Sumikawa K

更新日期：2006-03-17 00:00:00

abstract：:This study investigates the reanalysis processes as a consequence of conflict between incompatible sentential representations in sentence comprehension. Using the event-related potential (ERP) technique, we examined the situation in which the sentential representation built upon world knowledge (i.e., the plausibility...

journal_title：Brain research

authors： Ye Z,Zhou X

更新日期：2008-04-08 00:00:00

abstract：:Wayfinding is a complex cognitive function involving different types of information, such as knowledge about landmarks and direction information. This variety of processes suggest that multiple neural mechanisms are involved, e.g., the hippocampal system, the posterior parietal and temporal cortical areas. Although pa...

journal_title：Brain research

authors： van Asselen M,Kessels RP,Kappelle LJ,Neggers SF,Frijns CJ,Postma A

更新日期：2006-01-05 00:00:00

abstract：:A new compound, 3-((+/-)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP), has been evaluated as an excitatory amino acid receptor antagonist using electrophysiological assays and radioligand binding. In autoradiographic preparations, CPP reduces L-[3H]glutamate binding in regions of the hippocampus rich in N-m...

journal_title：Brain research

authors： Harris EW,Ganong AH,Monaghan DT,Watkins JC,Cotman CW

更新日期：1986-09-10 00:00:00

abstract：:Visually identified and electrophysiologically characterized sympathetic preganglionic neurons (SPNs) were recorded using the whole-cell voltage clamp technique in slices of neonatal rat spinal cord. Monosynaptic excitatory postsynaptic currents (EPSCs) were evoked by electrical stimulation of the nucleus intercalatus...

journal_title：Brain research

authors： Miyazaki T,Kobayashi H,Tosaka T

更新日期：1998-04-20 00:00:00

abstract：:There exists evidence to support the notion that the segmental reflex system is not fixed and inflexible, but rather is highly modifiable under a variety of circumstances. In this study the H-wave and M-wave recruitment curves were obtained from 19 subjects, utilizing the procedures outlined by Hugon. Each subject was...

journal_title：Brain research

authors： Koceja DM,Trimble MH,Earles DR

更新日期：1993-11-26 00:00:00

abstract：:The bioelectric activity of the rat superior cervical ganglion (SCG) infected with pseudorabies virus (PRV) was examined in vitro 30-38 h after inoculation. Simultaneous intra- and extracellular recordings on the internal (ICN) and external carotid nerves (ECN) revealed a synchronized spontaneous activity. This synchr...

journal_title：Brain research

authors： Kiraly M,Dolivo M

更新日期：1982-05-20 00:00:00

abstract：:After traumatic brain injury, extracellular K(+) in brain can dramatically increase. We studied the effects of increased K(+) on the isolated pressurized rat middle cerebral artery (MCA). MCAs (200-250 microm OD) were isolated, cannulated with glass micropipettes, and pressurized. K(+) was increased in the extralumina...

journal_title：Brain research

authors： Golding EM,Steenberg ML,Johnson TD,Bryan RM Jr

更新日期：2000-10-13 00:00:00

abstract：:The distribution of neurocalcin-immunoreactive (NC-ir) primary sensory neurons was examined in the trigeminal ganglion (TG), mesencephalic trigeminal tract nucleus (Mes5) and intraoral structures. NC-ir primary sensory neurons were located in the TG but not the Mes5. The coexpression study demonstrated that virtually ...

journal_title：Brain research

authors： Ichikawa H,Hidaka H,Sugimoto T

更新日期：2000-05-02 00:00:00

abstract：:The potential evoked in the pyriform cortex by single-pulse stimulation of the olfactory bulb was examined before and after single and repeated elicitation of an epileptiform afterdischarge produced by stimulation of the olfactory bulb. A single afterdischarge (AD) produced a rapid (i.e. within 5 min) increase in the ...

journal_title：Brain research

authors： Russell RD,Stripling JS

更新日期：1985-12-30 00:00:00

abstract：:Microglial reactivity in the red nucleus of rats was studied following upper cervical and lower thoracic rubrospinal tractotomy using the lectin binding method. Following axotomy, the contralateral nucleus containing the axotomized neurons was identified using the retrograde tracer Fast blue. It was subdivided into do...

journal_title：Brain research

authors： Tseng GF,Wang YJ,Lai QC

更新日期：1996-04-09 00:00:00

abstract：:Trophic effects of neurturin, a member of the glial cell line-derived neurotrophic factor-family, have been demonstrated on mesencephalic dopaminergic neurons, suggesting its therapeutic potential for Parkinson's disease. This study was designed to test the neuroprotective and regenerative effects of an intrastriatal ...

journal_title：Brain research

authors： Oiwa Y,Yoshimura R,Nakai K,Itakura T

更新日期：2002-08-30 00:00:00