Abstract：
:The specific brain structures or neural mechanisms underlying dysfunction in individuals with Attention-Deficit/Hyperactivity Disorder (ADHD) are not well established, particularly in regard to white matter (WM). Diffusion tensor imaging (DTI) was used to investigate WM in 12 adolescent males diagnosed with ADHD only and 12 typically developing controls (group matched; mean age=15.64 years, SD=1.15). In addition to fractional anisotropy (FA), we also examined axial and radial diffusivity (AD and RD) in an effort to help elucidate conflicting findings suggesting that both lower and higher FA values are characteristic of ADHD. Tract-based spatial statistics and voxel-wide analyses were conducted on the data utilizing a pre-frontal mask to enable focus on fronto-striatal and prefrontal pathways. Adolescents with ADHD had significantly higher FA and AD values in fronto-striatal pathways compared with controls. No differences were observed for RD. These results contribute to the growing literature implicating prefrontal WM variations in neuropsychiatric disorders, and are consistent with findings suggesting a role for fronto-striatal pathways in ADHD pathophysiology.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Tamm L,Barnea-Goraly N,Reiss ALdoi
10.1016/j.pscychresns.2012.04.001subject
Has Abstractpub_date
2012-05-31 00:00:00pages
150-4issue
2eissn
0165-1781issn
1872-7123pii
S0925-4927(12)00062-5journal_volume
202pub_type
杂志文章abstract：:The aim of this study was to investigate the blood lead level and parental marital status that might influence the development of attention-deficit/hyperactivity disorder (ADHD) symptoms in school-aged children. The participants in the survey included elementary school children, and they were followed up biennially. T...
journal_title：Psychiatry research
pub_type： 杂志文章
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更新日期：2016-02-28 00:00:00
abstract：:The significance of neurological signs in schizophrenia is poorly understood. In part, this may reflect the marked variability in the methods of ascertainment in previous studies. The Neurological Evaluation Scale (NES) is designed to standardize the assessment of neurological impairment in schizophrenia. The battery ...
journal_title：Psychiatry research
pub_type： 杂志文章
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更新日期：1989-03-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2011.10.005
更新日期：2012-05-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
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更新日期：2015-06-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
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更新日期：2010-04-30 00:00:00
abstract：:This study was aimed to explore clinical differences between women and men with schizophrenia (SZ) in Latin-America. It was conducted in public mental health centers in Bolivia, Peru and Chile. Two hundred forty-seven SZ patients participated in the study, 83 (33.6%) were women and 115 (46.6%) were Aymara. Compared to...
journal_title：Psychiatry research
pub_type： 杂志文章
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更新日期：2018-08-01 00:00:00
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更新日期：1997-03-14 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
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更新日期：2008-04-15 00:00:00
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journal_title：Psychiatry research
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journal_title：Psychiatry research
pub_type： 杂志文章
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更新日期：2015-10-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2009.01.003
更新日期：2009-06-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(84)90082-9
更新日期：1984-12-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
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更新日期：2017-08-01 00:00:00
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pub_type： 杂志文章
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更新日期：2020-06-01 00:00:00
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pub_type： 杂志文章
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更新日期：2019-12-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2009.08.004
更新日期：2011-01-30 00:00:00
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更新日期：2018-06-01 00:00:00
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pub_type： 杂志文章
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更新日期：2018-06-01 00:00:00
abstract：:Exposure to traumatic events during childhood is associated with an elevated risk of adult obesity. It has been hypothesized that the psychological sequelae from childhood trauma account for this risk, though no study has examined whether an increased risk of obesity is found in persons without psychological disorders...
journal_title：Psychiatry research
pub_type： 杂志文章
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更新日期：2006-05-30 00:00:00
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journal_title：Psychiatry research
pub_type： 临床试验,杂志文章
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更新日期：1979-12-01 00:00:00
abstract：:A variety of studies were addressed to differentiate responders and non-responders to substitution treatment among heroin dependent patients, without conclusive findings. In particular, preliminary pharmacogenetic findings have been reported to predict treatment effectiveness in mental health and substance use disorde...
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更新日期：2014-01-30 00:00:00
abstract：:Increasing help-seeking behavior was one of the effective methods for suicide prevention. However, help-seeking behavior was less explored in rural China. In this study, we aimed to analyze the factors which were associated with help-seeking behavior among medically serious suicide attempters in rural China. Subjects ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2019.02.024
更新日期：2019-04-01 00:00:00
abstract：:As part of anational Finnish study on reproductive health of women with severe mental disorders, we compared pregnancy- and delivery-, and postpartum-related outcomes between women with schizophrenia (n = 3444) and those with schizoaffective disorder (n = 985), focusing on their singleton pregnancies after illness ons...
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pub_type： 杂志文章
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更新日期：2020-12-01 00:00:00
abstract：:We explored regional and total volumetric cerebellar differences in probands and their unaffected full siblings relative to typically developing participants. Participants included 94 (51 males) patients diagnosed with childhood onset schizophrenia (COS), 80 related non-psychotic siblings (37 males) and 110 (64 males)...
journal_title：Psychiatry research
pub_type： 杂志文章
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更新日期：2011-09-30 00:00:00
abstract：:The current paper evaluates Criterion B for Non-Suicidal Self-Injury Disorder, which states that non-suicidal self-injury (NSSI) must occur for at least one function. The majority of individuals who engage in NSSI report at least one function, so it is unclear if Criterion B provides diagnostic utility in individuals ...
journal_title：Psychiatry research
pub_type： 杂志文章
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更新日期：2016-10-30 00:00:00
abstract：:In this study, 53 Chinese COPD moderate outpatients and 50 health controls, matched for age, family income and education level, were recruited to assess the prevalence of Alexithymia and its relationship to socio-demographic factors and pulmonary function. Alexithymia was measured with 20-item Toronto Alexithymia Scal...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2011.10.018
更新日期：2012-07-30 00:00:00
abstract：:Absence of the adhesio interthalamica (AI) in schizophrenic first episode patients is suggestive for another marker of early developmental neuropathologic changes. Moreover, findings suggest that schizophrenic patients without AI are characterised by more severe negative symptoms. The study aims to investigate the pre...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0925-4927(02)00044-6
更新日期：2002-10-01 00:00:00
abstract：:A visual analogue scale to evaluate fatigue severity (VAS-F) was developed and tested in a sample of 75 healthy individuals and a sample of 57 patients undergoing medical evaluation for sleep disorders. The scale consists of 18 items related to fatigue and energy, has simple instructions, and is completed with minimal...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(91)90027-m
更新日期：1991-03-01 00:00:00
