Abstract:
:Exposure to traumatic events during childhood is associated with an elevated risk of adult obesity. It has been hypothesized that the psychological sequelae from childhood trauma account for this risk, though no study has examined whether an increased risk of obesity is found in persons without psychological disorders. We examined exposure to early life stressors and body mass index (BMI) in 696 adults without significant medical or psychiatric history. Bivariate correlation showed that the total number of early life stressors (r=0.08), age (r=0.19), and sex (r=0.16) were significantly related to adult BMI. Given the relationship between sex and BMI, we examined the contribution of early life stressors to adult obesity separately for men and women. In men, hierarchical regression showed that exposure to early life stressors predicted adult obesity. Specifically, history of being bullied/rejected (Obese 31%, Normal weight, 9%) and emotional abuse (Obese, 17%; Normal weight, 2%) predicted adult obesity after controlling for the effects of age. In women, no relationship between early life stressors and adult obesity was found. These findings suggest that multiple processes mediate the relationship between early life stress and adult obesity and that their relative contributions may differ between men and women.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Gunstad J,Paul RH,Spitznagel MB,Cohen RA,Williams LM,Kohn M,Gordon Edoi
10.1016/j.psychres.2005.11.007subject
Has Abstractpub_date
2006-05-30 00:00:00pages
31-7issue
1eissn
0165-1781issn
1872-7123pii
S0165-1781(05)00372-0journal_volume
142pub_type
杂志文章abstract::Platelet monoamine oxidase (MAO) activity and intellectual level were examined in a large series of 1,129 18-year-old boys, selected from the general population. Personality traits were determined by means of selected subscales from several personality inventories such as the Zuckerman Sensation Seeking Scale, the Eys...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(84)90134-3
更新日期:1984-05-01 00:00:00
abstract::The goal of the study was to describe with prospective methodology the therapeutic response to nortriptyline in the respiratory panic disorder (PD) subtype versus the non-respiratory subtype. A total of 118 PD outpatients (DSM-IV) were previously divided into respiratory (n=77) and non-respiratory (n=41) subtypes and ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(03)00132-x
更新日期:2003-10-15 00:00:00
abstract::Despite mounting evidence for the distinctiveness of symptom dimensions in obsessive-compulsive disorder, neuropsychological studies have been few, focused on small samples, and relying on classification of participants based on mutually exclusive symptom categories, resulting in lack of concordance across neuropsycho...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.12.044
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Declarative memory disturbances, known to substantially contribute to cognitive impairment in schizophrenia, have previously been attributed to prefrontal as well as hippocampal dysfunction. AIMS:To characterize the role of prefrontal and mesolimbic/hippocampal dysfunction during memory encoding in schizoph...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2010.03.007
更新日期:2010-09-30 00:00:00
abstract::A specific aspect of the motor output of patients with tardive dyskinesia was investigated with an experimental procedure referenced in force control function (i.e., the maintenance of sustained force output). We hypothesized that response output (button press) at a given level would be significantly altered when prec...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(94)90066-3
更新日期:1994-10-01 00:00:00
abstract::The jumping to conclusions bias (JTC), in which some people gather less information than others before making a decision, has been linked to delusions in psychosis. JTC is usually identified via the beads task, in which a sequence of beads (the "target" sequence) is used to measure the amount of evidence participants ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.04.043
更新日期:2018-07-01 00:00:00
abstract::The present study utilized factor analysis to investigate possible underlying processes in schizophrenic thought disorder. Using the Communication Disturbances Index [CDI; Arch. Gen. Psychiatry, 53, (1996) 358], a measure of disruption in the communication of meaning from speaker to listener, we examined the speech of...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(00)00239-0
更新日期:2001-02-14 00:00:00
abstract::Within diverse global populations, validated tools are needed to assess common mental disorders. The Patient Health Questionnaire-9 (PHQ-9) is one of the most commonly used depression screeners. However, the PHQ-9 has not been structurally validated among female migrant domestic workers (MDWs). Female MDWs constitute ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2020.113575
更新日期:2021-01-01 00:00:00
abstract::Human corticotropin releasing hormone (h-CRH) was administered to 14 patients with major depression, after premedication with an overnight dose of 1.5 mg dexamethasone. Cortisol response, expressed as area under the time course curve (AUC), was significantly higher in the 14 patients than in a group of 13 age-matched ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(91)90041-m
更新日期:1991-08-01 00:00:00
abstract::This study describes the Brief Inventory of Social Support Exchange Network (BISSEN) as a standardized brief inventory measuring various aspects of social support. We confirmed the reliability and validity for function and direction of support and standardized the BISSEN. For Sample 1, a stratified random sampling met...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.03.056
更新日期:2017-07-01 00:00:00
abstract::Genetic and environmental architecture of psychotic and obsessive symptoms are not completely elucidated. This study estimated for these symptoms (i) the genetic and environmental components, (ii) the within-individual association, and (iii) the extent to which this association originates from common genetic and envir...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2010.12.002
更新日期:2011-07-30 00:00:00
abstract::A review of medical charts over a 1-year period was carried out in a population of 213 Taiwanese psychiatric inpatients that included 106 patients with schizophrenia. In subgroup analyses within the group of patients with schizophrenia, no significant differences in serum cholesterol levels were found between paranoid...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(00)00206-7
更新日期:2000-10-30 00:00:00
abstract::Progressive supranuclear palsy (PSP) is a rare neurodegenerative disorder in which, classically, patients present with postural instability and falls, parkinsonism, and slowing of vertical saccades. PSP patients typically have deficits in cognitive functioning, difficulties with most daily activities, and present with...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2013.08.045
更新日期:2013-12-30 00:00:00
abstract::Attention-deficit hyperactivity disorder is a common finding in school children. Because it was suggested to be related to frontal lobe dysfunction, we hypothesized that brain activation would be altered during an event-related color-word matching Stroop task in comparison to a healthy control group. Twelve medication...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2008.10.003
更新日期:2009-09-30 00:00:00
abstract::Major depressive disorder (MDD) is associated with abnormalities in emotional/cognitive processing and low reward sensitivity. The habenula has a pivotal role in these processes that may contribute to depression. However, there has been little research on the abnormal connectivity between the habenula and whole brain ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2020.112837
更新日期:2020-01-31 00:00:00
abstract::We aimed to assess the association between core cerebrospinal fluid (CSF) biomarkers, regional brain atrophy and clinical severity in the Alzheimer's disease (AD) continuum, as well as to investigate how cognitive reserve (CR) may modulate these putative associations. Forty-nine subjects (11 controls, 10 patients with...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2010.12.001
更新日期:2011-06-30 00:00:00
abstract::An epidemiological survey on anorexia nervosa was performed in Japanese hospitals in 1985 and 1992 using a questionnaire. The reported number of patients with anorexia nervosa was 2391 from 732 institutions. From these data, the total number of anorexia nervosa patients treated in 1985 in Japanese hospitals was estima...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(96)02988-5
更新日期:1996-04-16 00:00:00
abstract::Previous functional neuroimaging studies of posttraumatic stress disorder (PTSD) have mainly focused on symptom-provocation paradigms in combat-related PTSD. We sought to elucidate the effect of non-combat-related PTSD on the physiology of social cognition. Thirteen patients with PTSD underwent functional magnetic res...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2005.05.012
更新日期:2005-10-30 00:00:00
abstract::Although emotional dysfunction is presumed to be a central part of the deficit syndrome in schizophrenia, it has not yet been empirically investigated in deficit and non-deficit patients. Emotional responding was examined in 19 male deficit patients, 22 non-deficit patients, and 20 non-patient controls. Patients parti...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(99)00083-9
更新日期:1999-11-29 00:00:00
abstract::Evidence contributing to the understanding of neurobiological mechanisms underlying appetite dysregulation in anorexia nervosa draws heavily on separate lines of research into neuroendocrine and neural circuitry functioning. In particular, studies consistently cite elevated ghrelin and abnormal activation patterns in ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2014.04.015
更新日期:2014-08-30 00:00:00
abstract::The aim of this work is to empirically generate a shortened version of the Geriatric Depression Scale (GDS), with the intention of maximising the diagnostic performance in the detection of depression compared with previously GDS validated versions, while optimizing the size of the instrument. A total of 233 individual...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2009.02.018
更新日期:2010-06-30 00:00:00
abstract::Up to 90% of individuals with schizophrenia suffer from nicotine dependence. Both schizophrenia and nicotine consumption have strong genetic components, which may overlap. The relationship between schizophrenia and nicotine dependence remains unclear, due in part to confounding factors. Studies of the relationship bet...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2012.07.054
更新日期:2012-12-30 00:00:00
abstract::Cytochrome P450 C19 (CYP2C19) metabolizes exogenous and endogenous compounds. Although CYP2C19 is highly expressed in the liver, it is also expressed in the brain during early life. Previous human and animal studies have linked CYP2C19 genotype-predicted enzyme activity to hippocampal volumes, depressive symptoms, and...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2020.112984
更新日期:2020-06-01 00:00:00
abstract::It has been reported that the balance between T-helper type 1 (Th1) cytokines and T-helper type 2 (Th2) cytokines plays a role in psychiatric disorders such as bipolar disorder. The T-helper type 3 (Th3) cytokine, which transforming growth factor beta-1 (TGF-beta1), has been shown to modulate the production of Th1 and...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2004.08.005
更新日期:2004-12-30 00:00:00
abstract:OBJECTIVE:Paliperidone, a second-generation antipsychotic, has been found to have minimal hepatotoxicity in patients with schizophrenia. However, long-term hepatic outcome in patients with schizophrenia and viral hepatitis remains unclear. METHODS:Data obtained from the Taiwan National Health Insurance Research Databa...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2019.112597
更新日期:2019-11-01 00:00:00
abstract::Emotion has been conceptualized as a dimensional construct, while the number of dimensions - two or three - has been debated. Research has consistently identified two dimensions - valence and arousal - though ample evidence exists that three dimensions are necessary to describe emotion. One proposed third dimension, i...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2013.11.007
更新日期:2014-02-28 00:00:00
abstract::A woman complained of feeling a "metal-like thing" in her oral cavity 4 years after a stroke. She was convinced of the physical nature of her complaint despite intact dental and neurological findings. Somatosensory evoked magnetic fields suggested that her decreased right SII function was compensated for by the right ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2005.10.003
更新日期:2006-01-30 00:00:00
abstract::Choline chloride (2g q.i.d.) and placebo were admin stered to nine young adults in a placebo-drug-placebo design. Subjects took memory tests at the end of both placebo periods and at the end of the choline period. All nine subjects had participated in a previous study in which 1.0 mg of physostigmine infused over a 1-...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(80)90071-2
更新日期:1980-05-01 00:00:00
abstract::Cannabis is widely used in adolescence; however, the effects of cannabis on the developing brain remain unclear. Cannabis might be expected to have increased effects upon brain development and cognition during adolescence. There is extensive re-organisation of grey (GM) and white matter (WM) at this time, while the en...
journal_title:Psychiatry research
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.pscychresns.2013.07.012
更新日期:2013-12-30 00:00:00
abstract::We have previously reported decreased heart rate variability upon standing in panic disorder patients compared with controls. In this study, we extend our report to include patients with major depression (n = 19). Compared to normal controls (n = 20) and panic disorder patients (n = 30), there was no significant diffe...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(91)90104-w
更新日期:1991-04-01 00:00:00