Abstract:
:Weight gain is a side effect of antipsychotic medication and highly prevalent in people with schizophrenia or bipolar disorder, increasing their overall cardio-metabolic risk. We conducted a systematic review on non-pharmacological interventions for preventing/reducing weight gain or increase in waist-circumference in young, newly diagnosed patients with schizophrenia or bipolar disorder. We searched major electronic databases from inception to 04/2019 on RCTs, pre- and post-test studies, and non-randomized controlled clinical trials. From a potential of 2963 hits, eight studies met the inclusion criteria (n = 438, mean age of 18.8 (13-45) years). The interventions comprised supervised and individually adjusted aerobic exercise activities (5 studies), individual lifestyle counselling vs. control condition (2 RCTs), and dietetic counselling and practical training of cooking and shopping (1 study). Physical activity and practical dietetic interventions seem to be more efficient than lifestyle counselling. However, the results shall be taken with caution due to the non-randomized designs and other methodologically deficits in the majority of the included studies.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Nyboe L,Lemcke S,Møller AV,Stubbs Bdoi
10.1016/j.psychres.2019.112556subject
Has Abstractpub_date
2019-11-01 00:00:00pages
112556eissn
0165-1781issn
1872-7123pii
S0165-1781(19)31387-3journal_volume
281pub_type
杂志文章abstract::There have been scanty reports of the clinical features of schizophrenic patients treated with electroconvulsive therapy (ECT). This prospective study examined clinical characteristics and predictive factors associated with therapeutic outcome. Two hundred and ninety-three patients with refractory schizophrenia were t...
journal_title:Psychiatry research
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pub_type: 临床试验,杂志文章,随机对照试验
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