Abstract：
:Joint effects of genotype and the environment have turned out to be significant in the development of psychotic disorders. The purpose of the present study was to assess the association of an adoptive child׳s thought and schizophrenia spectrum disorders with genetic and environmental risk indicators and their interactions. A subgroup of the total sample used in the Finnish Adoptive Family Study was considered in the present study. The subjects were 125 adoptees at a high (n=53) or low (n=72) genetic risk of schizophrenia spectrum disorders and their adoptive parents. The risk factors evaluated were the adoptive child's genetic risk for schizophrenia spectrum disorders, winter or spring birth and parental Communication Deviance (CD). Thought disorders in the adoptees were assessed using the Thought Disorder Index and diagnoses were made according to DSM-III-R criteria. The adoptive child׳s Thought Disorder Index was only associated with parental Communication Deviance. The adoptive child's heightened genetic risk or winter or spring birth or parental CD or their interactions did not predict the adoptee's schizophrenia spectrum disorder. The results suggest that studies taking several risk indicators and their interactions into account may change views on the mutual significance of well-known risk factors.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Roisko R,Wahlberg KE,Hakko H,Tienari Pdoi
10.1016/j.psychres.2014.12.036subject
Has Abstractpub_date
2015-04-30 00:00:00pages
434-40issue
2-3eissn
0165-1781issn
1872-7123pii
S0165-1781(14)01029-4journal_volume
226pub_type
杂志文章abstract：:This study explored the influence of attachment on psychiatric treatment by considering attitudes towards and the use of psychotropic medication and psychotherapy in patients with depressive and anxiety disorders. Adults referred to a psychiatrist completed self-report measures and participated in a diagnostic intervi...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2017.06.050
更新日期：2017-10-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2016.10.036
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2013.01.031
更新日期：2013-10-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0925-4927(96)03017-x
更新日期：1997-03-14 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
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更新日期：2018-12-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2009.07.006
更新日期：2010-01-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
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更新日期：1996-11-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2017.05.021
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2013.08.025
更新日期：2013-12-30 00:00:00
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journal_title：Psychiatry research
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doi：10.1016/j.psychres.2017.08.083
更新日期：2017-12-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.psychres.2020.113635
更新日期：2021-01-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章,评审
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更新日期：2019-03-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0165-1781(98)00071-7
更新日期：1998-09-21 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2011.05.039
更新日期：2011-10-30 00:00:00
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journal_title：Psychiatry research
pub_type： 临床试验,杂志文章
doi：10.1016/0165-1781(88)90103-5
更新日期：1988-09-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2004.07.006
更新日期：2004-12-15 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2010.04.049
更新日期：2011-05-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2019.112519
更新日期：2019-10-01 00:00:00
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pub_type： 杂志文章
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2014.04.047
更新日期：2014-08-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2007.06.007
更新日期：2008-01-15 00:00:00
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doi：10.1016/j.psychres.2019.112567
更新日期：2019-11-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0165-1781(03)00199-9
更新日期：2003-11-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2014.01.024
更新日期：2014-05-30 00:00:00
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pub_type： 杂志文章
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journal_title：Psychiatry research
pub_type： 杂志文章,评审
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更新日期：2006-06-15 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0165-1781(97)00084-x
更新日期：1997-09-19 00:00:00
