Abstract:
:Because hypoactive delirium is especially under-recognized, we analyzed which Mini-Mental State Examination (MMSE) items predicted incident delirium and its hypoactive motor presentation. Over a 1-year period, older medical inpatients (n=291) were consecutively screened on admission with the Confusion Assessment Method-Spanish (CAM-S) to exclude prevalent delirium. Nondelirious patients were evaluated the same day with the MMSE, followed by daily ratings with the CAM-S. Those who became CAM-S positive were rated using the Delirium Rating Scale-Revised-98 to assess severity and motor subtype. Disorientation to time (OR 4.4, 95% CI 1.7-11.1) and place (OR 3.8, 95% CI 1.7-8.2) at admission were risk factors for delirium at follow-up and together correctly classified 88.3% of subjects as to delirium status. Disorientation to time and place, and visuoconstructional impairment were each associated with either hypoactive or mixed subtype (p<0.05 χ(2) test). Simple bedside evaluation of cognitive function in nondelirious patients revealed deficits that detected patients at risk for developing incident delirium at follow-up (especially hypoactive or mixed). We recommend patients with orientation deficits be monitored closely for emergence of delirium. A separate evaluation for possible dementia or other causes of cognitive impairment at admission should be considered too.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Gabriel Franco J,Santesteban O,Trzepacz P,Bernal C,Valencia C,Ocampo MV,Pablo Jd,Gaviria AM,Vilella Edoi
10.1016/j.psychres.2014.09.003subject
Has Abstractpub_date
2014-12-30 00:00:00pages
975-81issue
3eissn
0165-1781issn
1872-7123pii
S0165-1781(14)00762-8journal_volume
220pub_type
杂志文章abstract::Parental style and Cloninger's dimensions are associated with psychosis, but it is still unclear whether temperament, character and parenting variables are linked to specific psychotic symptoms. This study extends previous research exploring these issues. 78 patients with psychosis and 156 control subjects were recrui...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.08.066
更新日期:2018-11-01 00:00:00
abstract::Exposure to traumatic events during childhood is associated with an elevated risk of adult obesity. It has been hypothesized that the psychological sequelae from childhood trauma account for this risk, though no study has examined whether an increased risk of obesity is found in persons without psychological disorders...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2005.11.007
更新日期:2006-05-30 00:00:00
abstract::In a pilot study, affective components of pain were assessed using repetitive peripheral magnetic stimulation (rPMS) in patients with borderline personality disorder and healthy controls. Significant differences in pain thresholds and in affective components of pain between both groups were found. rPMS was well tolera...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2010.07.050
更新日期:2011-04-30 00:00:00
abstract::Moclobemide is a reversible, short-acting monoamine oxidase inhibitor (MAO1), specific for MAO A. To study moclobemide effects on the tyramine pressor response, we gave 12 depressed patients (2 males, 10 females; mean age 47, SD 11 years) an i.v. tyramine test after 7 days drug free. The mean (+/- SD) tyramine dose to...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(87)90036-9
更新日期:1987-11-01 00:00:00
abstract::Energy metabolism and immunity are characterized as abnormal in schizophrenia. Because these two systems are highly coordinated, we measured expression of prototypic obesogenic and immunogenic genes in freshly harvested PBMC from controls and participants with schizophrenia. We report significant increases in PPARγ, S...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.11.007
更新日期:2015-01-30 00:00:00
abstract::A range of executive function (EF) deficits have been associated with Borderline Personality (BPD), a disorder characterized by high rates of suicide. However, the role of EF and suicide risk in BPD has not been examined. This exploratory study compared working memory, Stroop interference, motor inhibition (SSRT) and ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2011.10.008
更新日期:2012-03-30 00:00:00
abstract::This study identified empirically derived subtypes of gamblers based on the Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV) diagnostic criteria for pathological gambling disorder (PGD). Data from the gamblers (n=5644) who participated in the 2007 British Gambling Prevalence Survey (BGPS) were analyse...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2009.11.010
更新日期:2010-07-30 00:00:00
abstract::We investigated platelet 14C-serotonin uptake and platelet [3H]LSD and [3H]paroxetine binding in 11 patients with seasonal affective disorder (SAD). Patients were reinvestigated after light therapy, applied at 07.00-09.00 h for 10 consecutive days. The degree of depression was rated before and after light therapy usin...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(98)00017-1
更新日期:1998-05-08 00:00:00
abstract::Sensitivity to blood, injury, and mutilation (SBIM) may increase risk for posttraumatic stress disorder (PTSD), given that traumatic events often involve actual or perceived threat of bodily harm to oneself and/or others, including exposure to blood and other mutilation-related stimuli. A self-report questionnaire was...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.01.058
更新日期:2017-04-01 00:00:00
abstract::Unhealthy behaviors and physical morbidity are more common among trauma survivors, especially those who suffer from posttraumatic stress disorder (PTSD). This study looked at the underexplored relationships between parental PTSD, unhealthy behaviors and aging of trauma survivors' offspring. Dyads of parents (mean age ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.11.060
更新日期:2019-01-01 00:00:00
abstract::The aim of the current study was to establish the prevalence of subthreshold body dysmorphic disorder (subthreshold-BDD) in a community sample of adolescents, and to compare disorder correlates in individuals with subthreshold-BDD to those with probable full-syndrome BDD (probable-BDD) and those without BDD (non-BDD)....
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.01.085
更新日期:2017-05-01 00:00:00
abstract::Neuroendocrine studies that examine the changes in serum prolactin levels following intramuscular (im) neuroleptics have usually monitored prolactin levels before and for 90 minutes to 3 hours after neuroleptic injection. Recent studies have suggested that this may be an inadequate period of time. In the present study...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(79)90056-8
更新日期:1979-10-01 00:00:00
abstract::Genotype frequencies of functional polymorphisms in the genes encoding the serotonin transporter (5-HTT) and the enzyme catechol-O-methyltransferase (COMT) were not different in 51 suicidal inpatients compared to 51 control subjects. Within the patient group, increased hopelessness and suicide ideation were associated...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(00)00128-1
更新日期:2000-02-14 00:00:00
abstract::Obesity depends on homeostatic and hedonic food intake behavior, mediated by brain plasticity changes in cortical and subcortical structures. The aim of this study was to investigate cortical thickness and subcortical volumes of regions related to food intake behavior in a healthy young adult sample with obesity. Thir...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2013.06.004
更新日期:2013-11-30 00:00:00
abstract::Quantitative electroencephalographic (QEEG) analyses are presented for a group of 90 subjects recovering from polysubstance abuse (median = 90 days abstinent) who preferentially used cocaine. QEEGs showed significant decreases from normal in both absolute and relative delta power and decreased theta power in both abso...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(95)02474-b
更新日期:1995-10-16 00:00:00
abstract::As the serotonin transporter gene (SLC6A4 or 5-HTT) is a key regulator of central serotonergic activity, several association studies between Antisocial Personality Disorder (APD) and the SLC6A4 polymorphisms have been conducted in the last decade. In the present study, the role of both 5-HTTLPR and 5-HTTVNTR polymorph...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2008.12.018
更新日期:2010-05-15 00:00:00
abstract::Clinical research across the developmental spectrum increasingly reveals the nuanced ways in which emotion and cognition can work to either support or derail rational (i.e., healthy or goal-consistent) decision making. However, psychological theories offer discrepant views on how these processes interact, and on wheth...
journal_title:Psychiatry research
pub_type: 杂志文章,评审
doi:10.1016/j.psychres.2019.01.048
更新日期:2019-03-01 00:00:00
abstract::This study examined compulsive sexual behavior (CSB) and psychopathology in a treatment-seeking sample of men in São Paulo, Brazil. Eighty-six men (26% gay, 17% bisexual, 57% heterosexual) who met diagnostic criteria for excessive sexual drive and sexual addiction completed assessments consisting of the Mini Internati...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2013.01.021
更新日期:2013-10-30 00:00:00
abstract::Computed tomography was used to compare the following three groups: obsessive-compulsive disorder (OCD) patients with high scores on a soft neurological sign examination, OCD patients with low soft neurological sign scores, and control subjects. Neuranatomical structures were measured using quantitative volumetric ana...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0925-4927(93)90026-e
更新日期:1993-10-01 00:00:00
abstract::Neurobiological mechanisms underlying the development of major depressive disorder (MDD) may differ depending on age-of-onset. Our aim was to compare patients who differ in age-of-onset, while controlling for illness duration, and number of depressive episodes. By directly comparing early-(EOD) and late-onset (LOD) pa...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2013.09.003
更新日期:2013-12-30 00:00:00
abstract::Family environment is a pathogenic factor of borderline personality disorder (BPD). However, the personality traits of patients with BPD and their parents have never been assessed using the same instrument and then examined for relationships. In the present study, we explored the temperament and character traits of BP...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2007.10.010
更新日期:2009-01-30 00:00:00
abstract::Left temporoparietal repetitive transcranial magnetic stimulation (rTMS) reportedly diminishes verbal hallucinations. A 21-year-old schizophrenic man, who had killed his mother in the belief that she was a demon, failed to respond to combined treatment with a variety of antipsychotic agents. His persistent hallucinati...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(03)00148-3
更新日期:2003-08-30 00:00:00
abstract::Most people with a serious mental illness experience significant functional impairment despite ongoing pharmacological treatment. Thus, in order to improve outcomes, a better understanding of functional predictors is needed. This study examined negative affect, a construct comprised of negative emotional experience, a...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.06.031
更新日期:2016-09-30 00:00:00
abstract::Reduction of volume and neuronal number has been found in several association nuclei of the thalamus in schizophrenic subjects. Recent evidence suggests that schizophrenic patients exhibit abnormalities in early visual processing and that many of the observed perceptual deficits are consistent with dysfunction of the ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2006.11.003
更新日期:2007-05-30 00:00:00
abstract::Affective temperament has been suggested as a potential mediator of the effect between genetic predisposition and neurocognitive functioning. As such, this report seeks to assess the extent of the correlation between affective temperament and cognitive function in a group of bipolar II subjects. 46 bipolar II outpatie...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.02.032
更新日期:2016-04-30 00:00:00
abstract:BACKGROUND:Several studies that have examined the full range of alcohol consumption have pointed to a possible non-linear association between alcohol use and the common mental disorders. Most of these studies are cross sectional and assessed psychiatric morbidity using non-specific instruments. Our aim was to investiga...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.05.049
更新日期:2016-09-30 00:00:00
abstract::Schizophrenia patients have well-established deficits in facial emotion perception, which contribute to their poor social functioning. A number of studies have related these deficits to a differential dysfunction in the magnocellular (M) versus parvocellular (P) visual pathway. We assessed 35 schizophrenia patients an...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.03.031
更新日期:2017-07-01 00:00:00
abstract::Depression is associated with a lowered degree of esterification of serum cholesterol, an increased C20:4omega6/C20:5omega3 ratio and decreases in omega3 fractions in fatty acids (FAs) or in the red blood cell membrane. The aims of the present study were to examine: (i) serum phospholipid and cholesteryl ester composi...
journal_title:Psychiatry research
pub_type: 临床试验,杂志文章
doi:10.1016/s0165-1781(99)00014-1
更新日期:1999-03-22 00:00:00
abstract::Recent studies have reported that patients with unipolar major depression may show a lower whole brain cerebral blood flow (CBF) and reduced regional CBF in frontal, temporal, and parietal lobes. The present study used single photon emission computed tomography (SPECT) with the CBF marker Tc-99m-hexamethylpropyleneami...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0925-4927(93)90012-7
更新日期:1993-06-01 00:00:00
abstract::Comorbid depression is frequent in obsessive-compulsive disorder (OCD) and is acknowledged as a major confound in biological and neurocognitive investigations in OCD. The aim of the present study was to assess the distribution of depressive symptoms in a large OCD sample (n=162) and to analyze the dimensional structur...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2003.11.003
更新日期:2004-02-15 00:00:00