Abstract：
:Green tea is reported to have wide ranging beneficial health outcomes across epidemiological studies, which have been attributed to its flavonoid content. We investigated whether the flavonoid epigallocatechin gallate (EGCG) modulates brain activity and self-reported mood in a double-blind, placebo controlled crossover study. Participants completed baseline assessments of cognitive and cardiovascular functioning, mood and a resting state electroencephalogram (EEG) before and then 120 min following administration of 300 mg EGCG or matched placebo. EGCG administration was associated with a significant overall increase in alpha, beta and theta activity, also reflected in overall EEG activity, more dominant in midline frontal and central regions, specifically in the frontal gyrus and medial frontal gyrus. In comparison to placebo the EGCG treatment also increased self-rated calmness and reduced self rated stress. This pattern of results suggests that participants in the EGCG condition may have been in a more relaxed and attentive state after consuming EGCG. This is in keeping with the widespread consumption of green tea for its purported relaxing/refreshing properties. The modulation of brain function due to EGCG is deserving of further controlled human studies.
journal_name
Appetitejournal_title
Appetiteauthors
Scholey A,Downey LA,Ciorciari J,Pipingas A,Nolidin K,Finn M,Wines M,Catchlove S,Terrens A,Barlow E,Gordon L,Stough Cdoi
10.1016/j.appet.2011.11.016subject
Has Abstractpub_date
2012-04-01 00:00:00pages
767-70issue
2eissn
0195-6663issn
1095-8304pii
S0195-6663(11)00645-3journal_volume
58pub_type
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