Abstract：
OBJECTIVES:The present study aims to establish the levels of acylated ghrelin, desacylated ghrelin, obestatin and preptin, during pregnancy and the postpartum period in pregnant women with Gestational Diabetes Mellitus (GDM) and healthy pregnancy women. DESIGN AND METHODS:The study registered 20 pregnant women with GDM and 20 healthy pregnant women. Fasting venous blood samples were collected from all cases between weeks 24 and 28 of pregnancy and after 24h postpartum. Hormones were analyzed using ELISA method. RESULTS:Serum acylated ghrelin (p:0.001), desacylated ghrelin (p:0.001), obestatin (p:0.006) and preptin (p:0.001) levels were all found statistically higher in both groups during the postpartum period, when compared to the pregnancy period. A positive correlation was established between desacylated ghrelin and acylated ghrelin (p:0.008), desacylated ghrelin and preptin (p:0.012) and preptin and insulin (p:0.039) in the GDM group during pregnancy. CONCLUSIONS:The studied hormones (especially desacylated ghrelin and obestatin) are critical in GDM pathophysiology based on the comparison of measure after and before the delivery.
journal_name
Clin Biochemjournal_title
Clinical biochemistryauthors
Baykus Y,Gurates B,Aydin S,Celik H,Kavak B,Aksoy A,Sahin I,Deniz R,Gungor S,Guzel SP,Minareci Ydoi
10.1016/j.clinbiochem.2011.08.1131subject
Has Abstractpub_date
2012-02-01 00:00:00pages
198-202issue
3eissn
0009-9120issn
1873-2933pii
S0009-9120(11)02593-8journal_volume
45pub_type
杂志文章abstract：OBJECTIVES:This study was undertaken to evaluate the relationship between serum bilirubin concentrations and the degree of urinary albumin excretion in hypertensive patients. DESIGN AND METHODS:A total of 120 hypertensive subjects were enrolled, in which 80 (67%) with normoalbuminuria (albumin excretion rate [AER] of ...
journal_title：Clinical biochemistry
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journal_title：Clinical biochemistry
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journal_title：Clinical biochemistry
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journal_title：Clinical biochemistry
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doi：10.1016/0009-9120(91)90541-l
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doi：10.1016/j.clinbiochem.2020.10.011
更新日期：2021-01-01 00:00:00
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pub_type： 临床试验,杂志文章
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更新日期：1991-06-01 00:00:00
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journal_title：Clinical biochemistry
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更新日期：2017-12-01 00:00:00
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journal_title：Clinical biochemistry
pub_type： 杂志文章
doi：10.1016/s0009-9120(78)90641-0
更新日期：1978-04-01 00:00:00
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journal_title：Clinical biochemistry
pub_type： 杂志文章,评审
doi：10.1016/j.clinbiochem.2010.08.008
更新日期：2011-01-01 00:00:00
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journal_title：Clinical biochemistry
pub_type： 杂志文章
doi：10.1016/j.clinbiochem.2009.02.001
更新日期：2009-05-01 00:00:00
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journal_title：Clinical biochemistry
pub_type： 杂志文章
doi：10.1016/j.clinbiochem.2008.04.005
更新日期：2008-07-01 00:00:00
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journal_title：Clinical biochemistry
pub_type： 杂志文章
doi：10.1016/j.clinbiochem.2011.06.983
更新日期：2011-10-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2019-10-01 00:00:00
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journal_title：Clinical biochemistry
pub_type： 杂志文章
doi：10.1016/j.clinbiochem.2015.11.009
更新日期：2016-04-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2003-06-01 00:00:00
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journal_title：Clinical biochemistry
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.clinbiochem.2016.04.006
更新日期：2016-07-01 00:00:00
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journal_title：Clinical biochemistry
pub_type： 杂志文章
doi：10.1016/j.clinbiochem.2011.08.1145
更新日期：2012-01-01 00:00:00
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journal_title：Clinical biochemistry
pub_type： 杂志文章
doi：10.1016/j.clinbiochem.2018.07.008
更新日期：2018-09-01 00:00:00
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journal_title：Clinical biochemistry
pub_type： 杂志文章
doi：10.1016/j.clinbiochem.2011.05.019
更新日期：2011-08-01 00:00:00
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journal_title：Clinical biochemistry
pub_type： 杂志文章
doi：10.1016/j.clinbiochem.2010.09.012
更新日期：2010-12-01 00:00:00
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journal_title：Clinical biochemistry
pub_type： 杂志文章
doi：10.1016/s0009-9120(02)00471-x
更新日期：2003-05-01 00:00:00
