Abstract：
VIDEO ABSTRACT:Why do people often choose to cooperate when they can better serve their interests by acting selfishly? One potential mechanism is that the anticipation of guilt can motivate cooperative behavior. We utilize a formal model of this process in conjunction with fMRI to identify brain regions that mediate cooperative behavior while participants decided whether or not to honor a partner's trust. We observed increased activation in the insula, supplementary motor area, dorsolateral prefrontal cortex (PFC), and temporal parietal junction when participants were behaving consistent with our model, and found increased activity in the ventromedial PFC, dorsomedial PFC, and nucleus accumbens when they chose to abuse trust and maximize their financial reward. This study demonstrates that a neural system previously implicated in expectation processing plays a critical role in assessing moral sentiments that in turn can sustain human cooperation in the face of temptation.
journal_name
Neuronjournal_title
Neuronauthors
Chang LJ,Smith A,Dufwenberg M,Sanfey AGdoi
10.1016/j.neuron.2011.02.056subject
Has Abstractpub_date
2011-05-12 00:00:00pages
560-72issue
3eissn
0896-6273issn
1097-4199pii
S0896-6273(11)00299-6journal_volume
70pub_type
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