Angiotensin converting enzyme inhibitors, thiazide diuretics and magnesium balance. A preliminary study.

Abstract:

:Serum and mononuclear cell magnesium content were determined in a cross-sectional study performed in four groups of hypertensive patients on chronic treatment with atenolol (n = 11), enalapril (n = 10), thiazide diuretics (n = 12), or enalapril + thiazides (n = 11). Our study shows that in patients treated with the thiazides alone, in spite of normal serum potassium and magnesium levels, mononuclear cell magnesium was decreased. To the extent that mononuclear Mg content mirrors the body ion stores, our results indicate that thiazides induce a Mg depletion not detectable by monitoring serum levels.

journal_name

Magnes Res

journal_title

Magnesium research

authors

Malini PL,Strocchi E,Valtancoli G,Ambrosioni E

subject

Has Abstract

pub_date

1990-09-01 00:00:00

pages

193-6

issue

3

eissn

0953-1424

issn

1952-4021

journal_volume

3

pub_type

杂志文章
  • Long-term follow-up after acute myocardial infarction in patients randomized to treatment with intravenous magnesium or intravenous propranolol in the acute phase.

    abstract::Ninety-five patients with acute myocardial infarction were followed up for 6 months to 3 years (mean 25.4 months) in a preliminary study to compare the effects of intravenous magnesium (49 patients) with that of intravenous propranolol (44 patients) given immediately after admission to the intensive care unit. There w...

    journal_title:Magnesium research

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Abraham AS,Balkin J,Rosenmann D,Ilan M,Klutstein M,Zion MM

    更新日期:1994-12-01 00:00:00

  • Effects of Mg2+, pH and PCr on cardiac excitation-metabolic coupling.

    abstract::A tight coupling between ionic currents, intracellular Ca2+ homeostasis, cytosolic [ADP] and deltaG of ATP hydrolysis underlies the regulation of cardiac cell function. As more experimental detail on the biochemistry and biophysics of these complex processes and their interactions accumulates, the intuitive interpreta...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Michailova A,McCulloch AD

    更新日期:2008-03-01 00:00:00

  • The relationship between magnesium and calciotropic hormones.

    abstract::There is an important functional link between magnesium and calciotropic hormones. PTH stimulates magnesium reabsorption in the renal tubule, absorption in the gut and release of the ion from bone. Magnesium on the other hand is essential for the normal function of the parathyroid glands, metabolism of vitamin D and a...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:

    authors: Zofková I,Kancheva RL

    更新日期:1995-03-01 00:00:00

  • Magnesium supplements may enhance the effect of antihypertensive medications in stage 1 hypertensive subjects.

    abstract:UNLABELLED:Comprehensive analytical review of 44 human studies in 43 publications of oral Magnesium (Mg) therapy for hypertension (HT) shows Mg supplements may enhance the blood-pressure (BP) lowering effect of anti-hypertensive medications (medications) in Stage 1 HT subjects. 9 studies conducted on subjects treated w...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2010.0198

    authors: Rosanoff A

    更新日期:2010-03-01 00:00:00

  • Ageing, hippocampal synaptic activity and magnesium.

    abstract::Ageing is associated with a general decline in physiological functions. Amongst the different aspects of body deterioration, cognitive impairments, and particularly defects in learning and memory, represent one of the most frequent features in the elderly. However, a great variability exists among aged subjects. Clini...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:

    authors: Billard JM

    更新日期:2006-09-01 00:00:00

  • The influence of alpha-zearalenol on magnesium concentration in cellular subfractions of certain tissues of female rats and their progeny.

    abstract::The purpose of the research work was to study the influence of alpha-zearalenol on magnesium concentration in cellular subfractions of certain tissues of female rats and their progeny. Pregnant female rats received alpha-zearalenol at the doses of: 0.05, 0.5 or 1 mg x kg(-1) b.w. After delivery, brain, liver and kidne...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Pasternak K,Kiełczykowska M,Sztanke M,Borzecki A

    更新日期:2003-06-01 00:00:00

  • Magnesium deficiency reduces fear-induced conditional lick suppression in mice.

    abstract::The consequences of broad-scale alterations in magnesium (Mg2+) levels on learning and memory are poorly understood. We have recently demonstrated that adult male mice maintained on an Mg2+-deficient diet exhibit reduced conditional freezing behavior. The purpose of the present study was to determine if the detrimenta...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Bardgett ME,Schultheis PJ,Muzny A,Riddle MD,Wagge JR

    更新日期:2007-03-01 00:00:00

  • FAST-Mag protocol with or without mild hypothermia (35°C) does not improve outcome after permanent MCAO in rats.

    abstract::The current study assessed the neuroprotective efficacy of magnesium using a FAST-Mag trial treatment protocol alone, and in combination with mild hypothermia, in Sprague Dawley rats subjected to permanent, middle cerebral artery occlusion (MCAO). Treatment with magnesium (MgSO4.7H2O) consisted of an intravenous loadi...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2013.0340

    authors: Meloni BP,Cross JL,Brookes LM,Clark VW,Campbell K,Knuckey NW

    更新日期:2013-04-01 00:00:00

  • Changes in the haemostatic profile during magnesium deficiency in swine.

    abstract::Epidemiological studies of populations living in areas of low magnesium (Mg) intake have consistently shown a higher cardiovascular morbidity. Several hypotheses have been advanced to explain the cardioprotective properties of magnesium. Few studies, however, have analysed the relation of magnesium to haemostasis. The...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Serebruany VL,Herzog WR,Edenbaum LR,Shustov AR,Gurbel PA

    更新日期:1996-10-01 00:00:00

  • Magnesium fluxes during lactation in the rat.

    abstract::Lactating rats fed a 0.055% Mg diet transferred 5.5 +/- SEM 0.3 mg per day of Mg into milk but remained in a slightly positive Mg balance by increasing both food consumption and fractional intestinal Mg absorption. Urinary Mg excretion increased continually during the course of lactation to values double those of non-...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Brommage R

    更新日期:1989-12-01 00:00:00

  • The degree of lymphocytic mitochondrial transmembrane potential and blood magnesium concentrations during coronary artery bypass grafting.

    abstract:UNLABELLED:Magnesium (Mg) plays an important role in lymphocyte function. Low blood concentration of Mg may result in intralymphocyte imbalance and in turn may be associated with intensified apoptosis of peripheral blood lymphocytes. Due to its multistage character; extracorporeal circulation (ECC) may augment Mg disor...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Korycińska A,Dabrowski W,Rzecki Z,Dragan M,Pozarowski P,Wrońska J,Stazka J,Pasternak K,Roliński J

    更新日期:2005-12-01 00:00:00

  • Protein peroxidation, magnesium deficiency and fibromyalgia.

    abstract::Lipid and protein peroxidations were investigated in female patients with magnesium deficit (MD), fibromyalgia (FM) and age matched controls: malondialdehyde and protein carbonyls (PC), as well as serum, leucocyte and erythrocyte magnesium (EMg) were assessed in 20 controls, 25 FM and 16 MD patients. MDA are unchanged...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Eisinger J,Zakarian H,Pouly E,Plantamura A,Ayavou T

    更新日期:1996-12-01 00:00:00

  • Magnesium and phase angle: a prognostic tool for monitoring cellular integrity in judo athletes.

    abstract::Adequate magnesium (Mg) levels play a vital role in membrane excitability, cell contractility and metabolism, being a key nutrient for sustaining appropriate muscular contraction and performance levels in athletes. Phase angle (PhA), assessed by bioimpedance analysis (BIA), has been reported to be positively associate...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2015.0389

    authors: Matias CN,Monteiro CP,Santos DA,Martins F,Silva AM,Laires MJ,Sardinha LB

    更新日期:2015-07-01 00:00:00

  • Voltage dependence of the pharmacological Mg2+ block of the Ca2+ entry into vascular smooth muscle cells.

    abstract::We studied the voltage dependence of the inhibitory effects of the Ca2+ antagonist Mg2+, compared to nifedipine, on the transsarcolemmal Ca2+ uptake into primary monolayers of smooth muscle cells obtained from pig coronary arteries. The cellular Ca incorporation was analyzed by liquid scintillation. Depolarization was...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Fleckenstein-Grün G,Matyas S,Dumont L

    更新日期:1997-06-01 00:00:00

  • Magnesium and selected parameters of the non-enzymatic antioxidant and immune systems and oxidative stress intensity in the seminal plasma of fertile males.

    abstract:INTRODUCTION:The present study investigated associations between environmental exposure to magnesium (Mg) and the levels of oxidative stress parameters and selected cytokines, and the antioxidant defense system in the seminal plasma of fertile males. MATERIALS AND METHODS:The study population consisted of 57 healthy, ...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2015.0377

    authors: Kasperczyk A,Dobrakowski M,Zalejska-Fiolka J,Horak S,Birkner E

    更新日期:2015-01-01 00:00:00

  • Magnesium deficiency-induced anorexia in hyperphagic obese Zucker rats.

    abstract::In clinical practice diabetes mellitus is the most significant cause of hypomagnesemia and Mg depletion. The obese Zucker rat approaches non-insulin-dependent type II diabetes; lean Zucker rats being suitable controls. Using this disease model the influence of dietary Mg deficiency was studied: animals received a diet...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Rattanatayarom W,Dorfmeister C,Classen UG,Schimatschek HF,Stein U,Classen HG

    更新日期:2001-09-01 00:00:00

  • Bone histomorphometry of ovariectomized or orchiectomized rats fed a moderately magnesium-deficient fructose diet and treated with exogenous oestrogen or testosterone.

    abstract::To investigate the effects of sex hormones on bone histomorphometry, and bone density (BMD), 10 week old ovariectomized (OVX), orchiectomized (ORX), and sham-operated (SHAM) rats fed a moderately magnesium-deficient fructose diet were studied. One third of the OVX and ORX rats were injected with beta-oestradiol-3-benz...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Koh ET,Yeh JK,Bourdeau JE,Chen MM,Om AS

    更新日期:1996-03-01 00:00:00

  • Comparison of a short irradiation (50 sec) by different wavelengths on audiogenic seizures in magnesium-deficient mice: evidence for a preventive neuroprotective effect of yellow.

    abstract::Audiogenic seizures triggered by an acoustic stimulus of determined frequency and amplitude have been described in many laboratory animals in many circumstances including magnesium deficiency. This model, recently validated, was used, in DBA/2 mice, to study the preventive neuroprotective effect of 6 wavelengths of th...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Pages N,Bac P,Maurois P,Durlach J,Agrapart C

    更新日期:2003-03-01 00:00:00

  • Plasma matrix metalloproteinase 9 correlates with disorders of brain magnesium homeostasis in patients undergoing coronary artery bypass surgery.

    abstract:BACKGROUND:Changes in plasma matrix metalloproteinase 9 (MMP-9) concentrations and parallel changes in brain magnesium homeostasis have not been examined in cardiac surgery patients. The purpose of the present study was to analyse these relationships in patients undergoing coronary artery bypass surgery (CABG) with ext...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2010.0219

    authors: Dabrowski W,Rzecki Z,Czajkowski M,Pilat J,Biernacka J,Kotlinska E,Pasternak K,Stążka K,Sztanke M,Sztanke K

    更新日期:2010-12-01 00:00:00

  • Association between low serum magnesium concentration and hyperuricemia.

    abstract:OBJECTIVES:To examine the cross-sectional associations between serum magnesium (Mg) and hyperuricemia (HU). METHODS:2904 subjects were included in this study. HU was defined as uric acid ≥416 μmol/L for the male population and ≥360 μmol/L for the female population. A multivariable logistic analysis model was applied t...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2015.0384

    authors: Zeng C,Wang YL,Wei J,Yang T,Li H,Xie DX,Li YS,Lei GH

    更新日期:2015-06-01 00:00:00

  • No positive effect of oral magnesium supplementation in the decreases of inflammation in subjects with prediabetes: a pilot study.

    abstract::To determine whether oral magnesium supplementation modifies serum levels of high-sensitivity C-reactive protein (hsCRP), TNF-alpha, IL-6, and IL-10 in subjects with prediabetes, inflammation, and hypomagnesemia, a total of 26 subjects men and non-pregnant women were included and randomly allocated to receive 30 ml of...

    journal_title:Magnesium research

    pub_type: 杂志文章,随机对照试验

    doi:10.1684/mrh.2012.0322

    authors: Simental-Mendía LE,Rodríguez-Morán M,Reyes-Romero MA,Guerrero-Romero F

    更新日期:2012-07-01 00:00:00

  • Dietary inulin in mice stimulates Mg2+ absorption and modulates TRPM6 and TRPM7 expression in large intestine and kidney.

    abstract::Complex fermentable carbohydrates, such as inulin-type fructans have been shown to improve Mg2+ absorption in the hindgut and body stores. The mechanisms for this are not well understood. The newly identified transient receptor potential melastatin 6 and 7 (TRPM6 and TRPM7) channels have been shown to function in acti...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Rondón LJ,Rayssiguier Y,Mazur A

    更新日期:2008-12-01 00:00:00

  • Magnesium and strength in elite judo athletes according to intracellular water changes.

    abstract::Magnesium (Mg) deficiency strongly affects muscle performance. In judo, many athletes often undergo impressive weight changes associated with severe dehydration. Common practices used by athletes to achieve a target weight can lead to Mg deficit. This study aimed to understand the impact of Mg changes on strength from...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2010.0217

    authors: Matias CN,Santos DA,Monteiro CP,Silva AM,Raposo Mde F,Martins F,Sardinha LB,Bicho M,Laires MJ

    更新日期:2010-09-01 00:00:00

  • Effect of an aerobic training on magnesium, trace elements and antioxidant systems in a Down syndrome population.

    abstract::The aim of the present study was to determine the effect of an aerobic training on plasma and red blood cells' levels of magnesium, copper, selenium and zinc and on some oxidative stress parameters in a Down syndrome (DS) sample population. Sixteen young male adults with DS participated in the protocol. Among them, ei...

    journal_title:Magnesium research

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Monteiro CP,Varela A,Pinto M,Neves J,Felisberto GM,Vaz C,Bicho MP,Laires MJ

    更新日期:1997-03-01 00:00:00

  • Are the transient receptor potential melastatin (TRPM) channels important in magnesium homeostasis following traumatic brain injury?

    abstract::Traumatic brain injury (TBI) confers a major burden to Western society and effective treatments are urgently required to improve the long-term deficits that inflict TBI survivors. Depletion of intracellular Mg(2+) is a well-known phenomenon occurring after TBI and is associated with poor neurological outcome. However,...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:10.1684/mrh.2009.0189

    authors: Cook NL,Van Den Heuvel C,Vink R

    更新日期:2009-12-01 00:00:00

  • Biomimetic study of the Ca(2+)-Mg2+ and K(+)-Li+ antagonism on biologically active sites: new methodology to study potential dependent ion exchange.

    abstract::Competitive divalent (magnesium and calcium) or monovalent (potassium, lithium and sodium) ion exchange and its influence on a membrane potential formation was studied at biological ligands (BL) such as adenosine triphosphate (ATP), asparagine (Asn) and glutamine (Gln) sites. The sites are dispersed electrochemically ...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Paczosa-Bator B,Stepien M,Maj-Zurawska M,Lewenstam A

    更新日期:2009-03-01 00:00:00

  • Comparison of the antinociceptive effect of systemic versus intrathecal magnesium sulphate on spinal morphine analgesia.

    abstract::The aim of this work was to compare the possible antinociceptive effect of the intravenous (IV) versus the intrathecal (IT) administration of magnesium sulphate prior to spinal morphine analgesia. This research was conducted in two sets: First; experimentally, to compare the antinociceptive effect of IT magnesium sulp...

    journal_title:Magnesium research

    pub_type: 杂志文章,随机对照试验

    doi:10.1684/mrh.2016.0396

    authors: Messeha MM,Boshra V

    更新日期:2016-03-01 00:00:00

  • The effects of magnesium supplementation on subjective anxiety.

    abstract::Experimental studies of anxiety in animal models, and evidence of efficacious outcomes of magnesium (Mg) supplementation in the treatment of acute clinical affective disorders, has increased interest in Mg as a potential novel treatment for symptoms of mild/moderate subjective anxiety. This short review examines the e...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:10.1684/mrh.2016.0411

    authors: Boyle NB,Lawton CL,Dye L

    更新日期:2016-03-01 00:00:00

  • The influence of magnesium supplementation on magnesium and calcium concentrations in hair of children with magnesium shortage.

    abstract::46 children, aged 2-6 years, with decreased magnesium concentrations in hair, were studied. Magnesium supplementation consisted of Asmag preparation for 3 months and multivitamin Multi-tabs preparation (containing magnesium, but without calcium) for the following 4 months. Control studies were performed again after 7 ...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Kozielec T,Sałacka A,Radomska K,Strecker D,Durska G

    更新日期:2001-03-01 00:00:00

  • Effect of magnesium pretreatment on reduced glutathione levels in tissues of mice exposed to acute and subacute cadmium intoxication: a time course study.

    abstract::The study was designed to investigate the role of magnesium (Mg) pretreatment on reduced glutathione (GSH) levels in kidney, liver and testis of mice intoxicated with cadmium (Cd). Animals were divided into four groups: I--controls, II--Cd group: mice intoxicated with Cd, III--Mg+Cd group: mice given Mg 1 h before Cd,...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Djukić-Cosić D,Ninković M,Malicević Z,Matović V,Soldatović D

    更新日期:2007-09-01 00:00:00