Angiotensin converting enzyme inhibitors, thiazide diuretics and magnesium balance. A preliminary study.

Abstract:

:Serum and mononuclear cell magnesium content were determined in a cross-sectional study performed in four groups of hypertensive patients on chronic treatment with atenolol (n = 11), enalapril (n = 10), thiazide diuretics (n = 12), or enalapril + thiazides (n = 11). Our study shows that in patients treated with the thiazides alone, in spite of normal serum potassium and magnesium levels, mononuclear cell magnesium was decreased. To the extent that mononuclear Mg content mirrors the body ion stores, our results indicate that thiazides induce a Mg depletion not detectable by monitoring serum levels.

journal_name

Magnes Res

journal_title

Magnesium research

authors

Malini PL,Strocchi E,Valtancoli G,Ambrosioni E

subject

Has Abstract

pub_date

1990-09-01 00:00:00

pages

193-6

issue

3

eissn

0953-1424

issn

1952-4021

journal_volume

3

pub_type

杂志文章
  • Influence of graded magnesium deficiencies on white blood cell counts and lymphocyte subpopulations in rats.

    abstract::Increased white blood cell counts or leukocytosis have been observed primarily in young rats fed diets extremely low in Mg (< 60 ppm) and high in phosphorus (0.5 % P). We investigated the influence that acute and moderate Mg deficiencies have on blood leukocytes at high and low dietary phosphorus levels. For four week...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Van Orden R,Eggett DL,Franz KB

    更新日期:2006-06-01 00:00:00

  • Comparison of a short irradiation (50 sec) by different wavelengths on audiogenic seizures in magnesium-deficient mice: evidence for a preventive neuroprotective effect of yellow.

    abstract::Audiogenic seizures triggered by an acoustic stimulus of determined frequency and amplitude have been described in many laboratory animals in many circumstances including magnesium deficiency. This model, recently validated, was used, in DBA/2 mice, to study the preventive neuroprotective effect of 6 wavelengths of th...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Pages N,Bac P,Maurois P,Durlach J,Agrapart C

    更新日期:2003-03-01 00:00:00

  • Acute myocardial infarction severity, complications, and mortality associated with lack of magnesium intake through consumption of desalinated seawater.

    abstract::Drinking water (DW) is an important dietary source of magnesium. Israel has recently increased desalinated seawater (DSW) production for DW, but negligible magnesium content in DSW may pose a risk of hypomagnesemia and consequential adverse cardiovascular effects. Consecutive acute myocardial infarction (AMI) patients...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2019.0449

    authors: Shlezinger M,Amitai Y,Goldenberg I,Atar S,Shechter M

    更新日期:2019-05-01 00:00:00

  • Experimental magnesium depletion in adult rabbits caused by blast overpressure.

    abstract::The complex pressure wave (blast) generated by some explosions causes pulmonary pathological changes which resemble the histological findings of the adult respiratory distress syndrome (ARDS). The development of indirect neurotrauma following experimental pulmonary blast injury has been shown previously. The purpose o...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Cernak I,Radosevic P,Malicevic Z,Savic J

    更新日期:1995-09-01 00:00:00

  • The relationship between magnesium and calciotropic hormones.

    abstract::There is an important functional link between magnesium and calciotropic hormones. PTH stimulates magnesium reabsorption in the renal tubule, absorption in the gut and release of the ion from bone. Magnesium on the other hand is essential for the normal function of the parathyroid glands, metabolism of vitamin D and a...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:

    authors: Zofková I,Kancheva RL

    更新日期:1995-03-01 00:00:00

  • Dietary inulin in mice stimulates Mg2+ absorption and modulates TRPM6 and TRPM7 expression in large intestine and kidney.

    abstract::Complex fermentable carbohydrates, such as inulin-type fructans have been shown to improve Mg2+ absorption in the hindgut and body stores. The mechanisms for this are not well understood. The newly identified transient receptor potential melastatin 6 and 7 (TRPM6 and TRPM7) channels have been shown to function in acti...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Rondón LJ,Rayssiguier Y,Mazur A

    更新日期:2008-12-01 00:00:00

  • Effect of magnesium pretreatment on reduced glutathione levels in tissues of mice exposed to acute and subacute cadmium intoxication: a time course study.

    abstract::The study was designed to investigate the role of magnesium (Mg) pretreatment on reduced glutathione (GSH) levels in kidney, liver and testis of mice intoxicated with cadmium (Cd). Animals were divided into four groups: I--controls, II--Cd group: mice intoxicated with Cd, III--Mg+Cd group: mice given Mg 1 h before Cd,...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Djukić-Cosić D,Ninković M,Malicević Z,Matović V,Soldatović D

    更新日期:2007-09-01 00:00:00

  • FAST-Mag protocol with or without mild hypothermia (35°C) does not improve outcome after permanent MCAO in rats.

    abstract::The current study assessed the neuroprotective efficacy of magnesium using a FAST-Mag trial treatment protocol alone, and in combination with mild hypothermia, in Sprague Dawley rats subjected to permanent, middle cerebral artery occlusion (MCAO). Treatment with magnesium (MgSO4.7H2O) consisted of an intravenous loadi...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2013.0340

    authors: Meloni BP,Cross JL,Brookes LM,Clark VW,Campbell K,Knuckey NW

    更新日期:2013-04-01 00:00:00

  • Enhanced contractile response to noradrenaline and calcium influx in thoracic aorta isolated from dietary magnesium deficient rats.

    abstract::Dependency on extracellular calcium influx in contractile response to noradrenaline has been investigated in the thoracic aorta isolated from dietary magnesium (Mg) deficient rats. Adult male Wistar rats were fed with a Mg deficient diet (0.001% Mg) for 30 days, together with control groups (0.07% Mg). The contractile...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Nishio A,Ishiguro S,Shimonishi I,Hirota A

    更新日期:1989-09-01 00:00:00

  • Magnesium supplements may enhance the effect of antihypertensive medications in stage 1 hypertensive subjects.

    abstract:UNLABELLED:Comprehensive analytical review of 44 human studies in 43 publications of oral Magnesium (Mg) therapy for hypertension (HT) shows Mg supplements may enhance the blood-pressure (BP) lowering effect of anti-hypertensive medications (medications) in Stage 1 HT subjects. 9 studies conducted on subjects treated w...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2010.0198

    authors: Rosanoff A

    更新日期:2010-03-01 00:00:00

  • Magnesium and the inflammatory response: potential pathophysiological implications in the management of patients with aneurysmal subarachnoid hemorrhage?

    abstract::Cerebral vasospasm and delayed cerebral ischemia remain an unsolved problem in patients with aneurysmal subarachnoid hemorrhage (SAH). In theory, high-dose magnesium sulfate (MgSO(4)) therapy offers vascular and neuroprotective benefits and is therefore currently under evaluation. The intensity of the inflammatory res...

    journal_title:Magnesium research

    pub_type: 临床试验,杂志文章

    doi:

    authors: Muroi C,Burkhardt JK,Hugelshofer M,Seule M,Mishima K,Keller E

    更新日期:2012-07-01 00:00:00

  • Effects of monovalent cations, pH and temperature on the dissociation constant (KD) for the fluorescent indicator mag-fura-2 at different excitation wavelengths.

    abstract::The use of fluorescent indicators to quantify intracellular magnesium ([Mg(2+)]i) requires accurate determination of the dissociation constant (K(D)). Ideally, the K(D) should be determined intracellularly; however, in practice this is difficult to achieve. An alternative method is to measure the K(D) in solutions whi...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Howarth FC,Singh J,Waring JJ,Hustler BI,Bailey M

    更新日期:1995-12-01 00:00:00

  • Magnesium deficiency-induced anorexia in hyperphagic obese Zucker rats.

    abstract::In clinical practice diabetes mellitus is the most significant cause of hypomagnesemia and Mg depletion. The obese Zucker rat approaches non-insulin-dependent type II diabetes; lean Zucker rats being suitable controls. Using this disease model the influence of dietary Mg deficiency was studied: animals received a diet...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Rattanatayarom W,Dorfmeister C,Classen UG,Schimatschek HF,Stein U,Classen HG

    更新日期:2001-09-01 00:00:00

  • Preliminary communication on intralymphocyte ionized magnesium in hypertensive patients under treatment with beta-blockers.

    abstract::We measured free intralymphocyte magnesium (Mgi) in 10 hypertensive subjects (HS) before and after treatment with atenolol (A) and in 16 normotensive control subjects (NC). We also carried out in vitro studies on human lymphocytes to test the effect of catecholamines and beta-antagonists on Mgi. Mgi in HS was not stat...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Pastori C,Delva P,Degan M,Lechi A

    更新日期:1999-03-01 00:00:00

  • Magnesium, adenosine triphosphate, and catecholamine complexes: application of new means of identifying solute-solute interactions of biological significance using NMR chemical shift data.

    abstract::The interaction of magnesium ions with biomolecular species is fundamental to the regulation of many biological processes. A mathematical technique to investigate such interactions is described. The concept of a pseudo-formation curve is discussed and the relevance and applicability of such constructions to the study ...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Hughes MS,Crow DR,Birch NJ

    更新日期:1992-06-01 00:00:00

  • Magnesium fluxes during lactation in the rat.

    abstract::Lactating rats fed a 0.055% Mg diet transferred 5.5 +/- SEM 0.3 mg per day of Mg into milk but remained in a slightly positive Mg balance by increasing both food consumption and fractional intestinal Mg absorption. Urinary Mg excretion increased continually during the course of lactation to values double those of non-...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Brommage R

    更新日期:1989-12-01 00:00:00

  • Magnesium and thermoregulation. I. Newborn and infant. Is sudden infant death syndrome a magnesium-dependent disease of the transition from chemical to physical thermoregulation?

    abstract::The sudden infant death syndrome (SIDS) remains a leading cause of death during the first year. The common epidemiological and pathological data which characterize SIDS include the curve for age at death (with 3 months as modal age), the stigmata of early maternal intrauterine injury, the seasonal predominance in wint...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:

    authors: Durlach J,Durlach V,Rayssiguier Y,Ricquier D,Goubern M,Bertin R,Bara M,Guiet-Bara A,Olive G,Mettey R

    更新日期:1991-09-01 00:00:00

  • The COVID-19 pandemic: is there a role for magnesium? Hypotheses and perspectives.

    abstract::More and more studies are accumulating about COVID-19. Some aspects of the pathogenesis of the disease recall events occurring in Mg deficiency, such as a drop of T cells, increased plasma concentration of inflammatory cytokines, and endothelial dysfunction. We hypothesize that a low Mg status, which is rather common,...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2020.0465

    authors: Iotti S,Wolf F,Mazur A,Maier JA

    更新日期:2020-05-01 00:00:00

  • Recent data on mitral valve prolapse and magnesium deficit.

    abstract::Idiopathic mitral valve prolapse (IMVP) is a widespread disease. IMVP may be latent, but most patients describe a great variety of symptoms. The clinical pictures of IMVP and of latent tetany are superimposed with regard to Mg deficit. IMVP appears as a late complication of latent tetany due to magnesium deficit (LTMD...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:

    authors: Zeana CD

    更新日期:1988-12-01 00:00:00

  • The degree of lymphocytic mitochondrial transmembrane potential and blood magnesium concentrations during coronary artery bypass grafting.

    abstract:UNLABELLED:Magnesium (Mg) plays an important role in lymphocyte function. Low blood concentration of Mg may result in intralymphocyte imbalance and in turn may be associated with intensified apoptosis of peripheral blood lymphocytes. Due to its multistage character; extracorporeal circulation (ECC) may augment Mg disor...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Korycińska A,Dabrowski W,Rzecki Z,Dragan M,Pozarowski P,Wrońska J,Stazka J,Pasternak K,Roliński J

    更新日期:2005-12-01 00:00:00

  • Magnesium and selected parameters of the non-enzymatic antioxidant and immune systems and oxidative stress intensity in the seminal plasma of fertile males.

    abstract:INTRODUCTION:The present study investigated associations between environmental exposure to magnesium (Mg) and the levels of oxidative stress parameters and selected cytokines, and the antioxidant defense system in the seminal plasma of fertile males. MATERIALS AND METHODS:The study population consisted of 57 healthy, ...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2015.0377

    authors: Kasperczyk A,Dobrakowski M,Zalejska-Fiolka J,Horak S,Birkner E

    更新日期:2015-01-01 00:00:00

  • TRPM7 involvement in cancer: a potential prognostic factor.

    abstract::Calcium (Ca(2+)) and magnesium (Mg(2+)) are important metal elements that regulate a variety of cellular processes such as proliferation, migration, and apoptosis, in cancer cells. Among the ionic channels mediating intracellular entry, the transient receptor potential melastatin type 7 (TRPM7) channel is of particula...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2014.0367

    authors: Dhennin-Duthille I,Gautier M,Korichneva I,Ouadid-Ahidouch H

    更新日期:2014-07-01 00:00:00

  • Plasma matrix metalloproteinase 9 correlates with disorders of brain magnesium homeostasis in patients undergoing coronary artery bypass surgery.

    abstract:BACKGROUND:Changes in plasma matrix metalloproteinase 9 (MMP-9) concentrations and parallel changes in brain magnesium homeostasis have not been examined in cardiac surgery patients. The purpose of the present study was to analyse these relationships in patients undergoing coronary artery bypass surgery (CABG) with ext...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2010.0219

    authors: Dabrowski W,Rzecki Z,Czajkowski M,Pilat J,Biernacka J,Kotlinska E,Pasternak K,Stążka K,Sztanke M,Sztanke K

    更新日期:2010-12-01 00:00:00

  • Voltage dependence of the pharmacological Mg2+ block of the Ca2+ entry into vascular smooth muscle cells.

    abstract::We studied the voltage dependence of the inhibitory effects of the Ca2+ antagonist Mg2+, compared to nifedipine, on the transsarcolemmal Ca2+ uptake into primary monolayers of smooth muscle cells obtained from pig coronary arteries. The cellular Ca incorporation was analyzed by liquid scintillation. Depolarization was...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Fleckenstein-Grün G,Matyas S,Dumont L

    更新日期:1997-06-01 00:00:00

  • Rumen epithelial cells adapt magnesium transport to high and low extracellular magnesium conditions.

    abstract::A protein of approximately 70-kDa was identified as a candidate Na+/Mg2+ exchanger in rumen epithelial cells (REC). Melastatin-related Transient Receptor Potential 7 (TRPM7) and Magnesium Transporter 1 (MagT1) transcripts and, from them, encoded proteins were also detected. The regulation of these Mg transport pathway...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Schweigel M,Kuzinski J,Deiner C,Kolisek M

    更新日期:2009-09-01 00:00:00

  • Magnesium deficiency reduces fear-induced conditional lick suppression in mice.

    abstract::The consequences of broad-scale alterations in magnesium (Mg2+) levels on learning and memory are poorly understood. We have recently demonstrated that adult male mice maintained on an Mg2+-deficient diet exhibit reduced conditional freezing behavior. The purpose of the present study was to determine if the detrimenta...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Bardgett ME,Schultheis PJ,Muzny A,Riddle MD,Wagge JR

    更新日期:2007-03-01 00:00:00

  • Bone histomorphometry of ovariectomized or orchiectomized rats fed a moderately magnesium-deficient fructose diet and treated with exogenous oestrogen or testosterone.

    abstract::To investigate the effects of sex hormones on bone histomorphometry, and bone density (BMD), 10 week old ovariectomized (OVX), orchiectomized (ORX), and sham-operated (SHAM) rats fed a moderately magnesium-deficient fructose diet were studied. One third of the OVX and ORX rats were injected with beta-oestradiol-3-benz...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Koh ET,Yeh JK,Bourdeau JE,Chen MM,Om AS

    更新日期:1996-03-01 00:00:00

  • Therapeutic effect of parenteral magnesium on noise-induced hearing loss in the guinea pig.

    abstract::We have recently demonstrated in the guinea pig that preventive dietary magnesium supplement can significantly reduce impulse noise induced hearing loss by on average 18 dB. The purpose of the present study was to examine whether magnesium might also have a therapeutic effect on noise trauma. Anesthetized guinea pigs ...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Scheibe F,Haupt H,Ising H,Cherny L

    更新日期:2002-03-01 00:00:00

  • The osmotic and intrinsic mechanisms of the pharmacological laxative action of oral high doses of magnesium sulphate. Importance of the release of digestive polypeptides and nitric oxide.

    abstract::A common use for high doses of oral magnesium salts is to produce a laxative effect to treat constipation. In the intestinal lumen the poorly absorbable magnesium ions (and other ions such as sulphate) exert an osmotic effect and cause water to be retained in the intestinal lumen. This increases the fluidity of the in...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:

    authors: Izzo AA,Gaginella TS,Capasso F

    更新日期:1996-06-01 00:00:00

  • Magnesium-based implants: a mini-review.

    abstract::The goal of this review is to bring to the attention of the readership of Magnesium Research another facet of the importance of magnesium, i.e. magnesium-based biomaterials. A concise history of biomaterials and magnesium are thus presented. In addition, historical and current, clinical magnesium-based applications ar...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:10.1684/mrh.2015.0375

    authors: Luthringer BJ,Feyerabend F,Willumeit-Römer R

    更新日期:2014-10-01 00:00:00