Angiotensin converting enzyme inhibitors, thiazide diuretics and magnesium balance. A preliminary study.

Abstract:

:Serum and mononuclear cell magnesium content were determined in a cross-sectional study performed in four groups of hypertensive patients on chronic treatment with atenolol (n = 11), enalapril (n = 10), thiazide diuretics (n = 12), or enalapril + thiazides (n = 11). Our study shows that in patients treated with the thiazides alone, in spite of normal serum potassium and magnesium levels, mononuclear cell magnesium was decreased. To the extent that mononuclear Mg content mirrors the body ion stores, our results indicate that thiazides induce a Mg depletion not detectable by monitoring serum levels.

journal_name

Magnes Res

journal_title

Magnesium research

authors

Malini PL,Strocchi E,Valtancoli G,Ambrosioni E

subject

Has Abstract

pub_date

1990-09-01 00:00:00

pages

193-6

issue

3

eissn

0953-1424

issn

1952-4021

journal_volume

3

pub_type

杂志文章
  • Association between low serum magnesium concentration and hyperuricemia.

    abstract:OBJECTIVES:To examine the cross-sectional associations between serum magnesium (Mg) and hyperuricemia (HU). METHODS:2904 subjects were included in this study. HU was defined as uric acid ≥416 μmol/L for the male population and ≥360 μmol/L for the female population. A multivariable logistic analysis model was applied t...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2015.0384

    authors: Zeng C,Wang YL,Wei J,Yang T,Li H,Xie DX,Li YS,Lei GH

    更新日期:2015-06-01 00:00:00

  • FAST-Mag protocol with or without mild hypothermia (35°C) does not improve outcome after permanent MCAO in rats.

    abstract::The current study assessed the neuroprotective efficacy of magnesium using a FAST-Mag trial treatment protocol alone, and in combination with mild hypothermia, in Sprague Dawley rats subjected to permanent, middle cerebral artery occlusion (MCAO). Treatment with magnesium (MgSO4.7H2O) consisted of an intravenous loadi...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2013.0340

    authors: Meloni BP,Cross JL,Brookes LM,Clark VW,Campbell K,Knuckey NW

    更新日期:2013-04-01 00:00:00

  • Ageing, hippocampal synaptic activity and magnesium.

    abstract::Ageing is associated with a general decline in physiological functions. Amongst the different aspects of body deterioration, cognitive impairments, and particularly defects in learning and memory, represent one of the most frequent features in the elderly. However, a great variability exists among aged subjects. Clini...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:

    authors: Billard JM

    更新日期:2006-09-01 00:00:00

  • The influence of magnesium supplementation on magnesium and calcium concentrations in hair of children with magnesium shortage.

    abstract::46 children, aged 2-6 years, with decreased magnesium concentrations in hair, were studied. Magnesium supplementation consisted of Asmag preparation for 3 months and multivitamin Multi-tabs preparation (containing magnesium, but without calcium) for the following 4 months. Control studies were performed again after 7 ...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Kozielec T,Sałacka A,Radomska K,Strecker D,Durska G

    更新日期:2001-03-01 00:00:00

  • Comparison of a short irradiation (50 sec) by different wavelengths on audiogenic seizures in magnesium-deficient mice: evidence for a preventive neuroprotective effect of yellow.

    abstract::Audiogenic seizures triggered by an acoustic stimulus of determined frequency and amplitude have been described in many laboratory animals in many circumstances including magnesium deficiency. This model, recently validated, was used, in DBA/2 mice, to study the preventive neuroprotective effect of 6 wavelengths of th...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Pages N,Bac P,Maurois P,Durlach J,Agrapart C

    更新日期:2003-03-01 00:00:00

  • Effect of a natural mineral-rich water on catechol-O-methyltransferase function.

    abstract::Catechol-O-methyltransferase (COMT) is a magnesium-dependent, catecholamine-metabolizing enzyme, whose impaired activity has been positively associated with cardiovascular diseases, particularly hypertension. Consumption of some natural mineral-rich waters has been shown to exert protective effects on cardiovascular r...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2014.0369

    authors: Bastos P,Araújo JR,Azevedo I,Martins MJ,Ribeiro L

    更新日期:2014-07-01 00:00:00

  • The influence of alpha-zearalenol on magnesium concentration in cellular subfractions of certain tissues of female rats and their progeny.

    abstract::The purpose of the research work was to study the influence of alpha-zearalenol on magnesium concentration in cellular subfractions of certain tissues of female rats and their progeny. Pregnant female rats received alpha-zearalenol at the doses of: 0.05, 0.5 or 1 mg x kg(-1) b.w. After delivery, brain, liver and kidne...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Pasternak K,Kiełczykowska M,Sztanke M,Borzecki A

    更新日期:2003-06-01 00:00:00

  • Magnesium fluxes during lactation in the rat.

    abstract::Lactating rats fed a 0.055% Mg diet transferred 5.5 +/- SEM 0.3 mg per day of Mg into milk but remained in a slightly positive Mg balance by increasing both food consumption and fractional intestinal Mg absorption. Urinary Mg excretion increased continually during the course of lactation to values double those of non-...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Brommage R

    更新日期:1989-12-01 00:00:00

  • Magnesium-based implants: a mini-review.

    abstract::The goal of this review is to bring to the attention of the readership of Magnesium Research another facet of the importance of magnesium, i.e. magnesium-based biomaterials. A concise history of biomaterials and magnesium are thus presented. In addition, historical and current, clinical magnesium-based applications ar...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:10.1684/mrh.2015.0375

    authors: Luthringer BJ,Feyerabend F,Willumeit-Römer R

    更新日期:2014-10-01 00:00:00

  • Influence of graded magnesium deficiencies on white blood cell counts and lymphocyte subpopulations in rats.

    abstract::Increased white blood cell counts or leukocytosis have been observed primarily in young rats fed diets extremely low in Mg (< 60 ppm) and high in phosphorus (0.5 % P). We investigated the influence that acute and moderate Mg deficiencies have on blood leukocytes at high and low dietary phosphorus levels. For four week...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Van Orden R,Eggett DL,Franz KB

    更新日期:2006-06-01 00:00:00

  • TRPM7 involvement in cancer: a potential prognostic factor.

    abstract::Calcium (Ca(2+)) and magnesium (Mg(2+)) are important metal elements that regulate a variety of cellular processes such as proliferation, migration, and apoptosis, in cancer cells. Among the ionic channels mediating intracellular entry, the transient receptor potential melastatin type 7 (TRPM7) channel is of particula...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2014.0367

    authors: Dhennin-Duthille I,Gautier M,Korichneva I,Ouadid-Ahidouch H

    更新日期:2014-07-01 00:00:00

  • Therapeutic effect of parenteral magnesium on noise-induced hearing loss in the guinea pig.

    abstract::We have recently demonstrated in the guinea pig that preventive dietary magnesium supplement can significantly reduce impulse noise induced hearing loss by on average 18 dB. The purpose of the present study was to examine whether magnesium might also have a therapeutic effect on noise trauma. Anesthetized guinea pigs ...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Scheibe F,Haupt H,Ising H,Cherny L

    更新日期:2002-03-01 00:00:00

  • The degree of lymphocytic mitochondrial transmembrane potential and blood magnesium concentrations during coronary artery bypass grafting.

    abstract:UNLABELLED:Magnesium (Mg) plays an important role in lymphocyte function. Low blood concentration of Mg may result in intralymphocyte imbalance and in turn may be associated with intensified apoptosis of peripheral blood lymphocytes. Due to its multistage character; extracorporeal circulation (ECC) may augment Mg disor...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Korycińska A,Dabrowski W,Rzecki Z,Dragan M,Pozarowski P,Wrońska J,Stazka J,Pasternak K,Roliński J

    更新日期:2005-12-01 00:00:00

  • Magnesium and ageing. II. Clinical data: aetiological mechanisms and pathophysiological consequences of magnesium deficit in the elderly.

    abstract::Ageing constitutes a risk factor for magnesium deficit. Primary magnesium deficit originates from two aetiological mechanisms: deficiency and depletion. Primary magnesium deficiency is due to insufficient magnesium intake. Dietary amounts of magnesium are marginal in the whole population whatever the age. Nutritional ...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:

    authors: Durlach J,Durlach V,Bac P,Rayssiguier Y,Bara M,Guiet-Bara A

    更新日期:1993-12-01 00:00:00

  • The osmotic and intrinsic mechanisms of the pharmacological laxative action of oral high doses of magnesium sulphate. Importance of the release of digestive polypeptides and nitric oxide.

    abstract::A common use for high doses of oral magnesium salts is to produce a laxative effect to treat constipation. In the intestinal lumen the poorly absorbable magnesium ions (and other ions such as sulphate) exert an osmotic effect and cause water to be retained in the intestinal lumen. This increases the fluidity of the in...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:

    authors: Izzo AA,Gaginella TS,Capasso F

    更新日期:1996-06-01 00:00:00

  • Long-term follow-up after acute myocardial infarction in patients randomized to treatment with intravenous magnesium or intravenous propranolol in the acute phase.

    abstract::Ninety-five patients with acute myocardial infarction were followed up for 6 months to 3 years (mean 25.4 months) in a preliminary study to compare the effects of intravenous magnesium (49 patients) with that of intravenous propranolol (44 patients) given immediately after admission to the intensive care unit. There w...

    journal_title:Magnesium research

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Abraham AS,Balkin J,Rosenmann D,Ilan M,Klutstein M,Zion MM

    更新日期:1994-12-01 00:00:00

  • Enhanced contractile response to noradrenaline and calcium influx in thoracic aorta isolated from dietary magnesium deficient rats.

    abstract::Dependency on extracellular calcium influx in contractile response to noradrenaline has been investigated in the thoracic aorta isolated from dietary magnesium (Mg) deficient rats. Adult male Wistar rats were fed with a Mg deficient diet (0.001% Mg) for 30 days, together with control groups (0.07% Mg). The contractile...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Nishio A,Ishiguro S,Shimonishi I,Hirota A

    更新日期:1989-09-01 00:00:00

  • Influence of endothelium in the in vitro vasorelaxant effect of magnesium on aortic basal tension in DOCA-salt hypertensive rat.

    abstract::The objective of this study was to examine the influence of the endothelium on the extracellular magnesium induced relaxation of basal tension in isolated aortas from both mineralocorticoid-salt (DOCA-salt) hypertensive and control normotensive Sprague Dawley male rats. After incubation in magnesium-free physiological...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Laurant P,Berthelot A

    更新日期:1992-12-01 00:00:00

  • Magnesium and its relationship to C-reactive protein among hemodialysis patients.

    abstract::Hypomagnesaemia has been reported among patients undergoing hemodialysis (HD). Recently, a possible correlation between serum magnesium (Mg) and C-reactive protein (CRP) has been stressed. This correlation has been attributed to cytokine production and oxidative stress processes. In this study we aimed to determine th...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Pakfetrat M,Malekmakan L,Roozbeh J,Haghpanah S

    更新日期:2008-09-01 00:00:00

  • Magnesium and selected parameters of the non-enzymatic antioxidant and immune systems and oxidative stress intensity in the seminal plasma of fertile males.

    abstract:INTRODUCTION:The present study investigated associations between environmental exposure to magnesium (Mg) and the levels of oxidative stress parameters and selected cytokines, and the antioxidant defense system in the seminal plasma of fertile males. MATERIALS AND METHODS:The study population consisted of 57 healthy, ...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2015.0377

    authors: Kasperczyk A,Dobrakowski M,Zalejska-Fiolka J,Horak S,Birkner E

    更新日期:2015-01-01 00:00:00

  • Magnesium, potassium flux and photosynthesis.

    abstract::Photosynthetic capacity of chloroplasts is regulated by stromal pH. The pH of the stroma must be maintained higher than external pH during illumination in order to optimize photosynthetic carbon reduction cycle activity. Stromal pH is affected by K+/H+ counterexchange across the chloroplast envelope. Magnesium ion ext...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:

    authors: Berkowitz GA,Wu W

    更新日期:1993-09-01 00:00:00

  • Voltage dependence of the pharmacological Mg2+ block of the Ca2+ entry into vascular smooth muscle cells.

    abstract::We studied the voltage dependence of the inhibitory effects of the Ca2+ antagonist Mg2+, compared to nifedipine, on the transsarcolemmal Ca2+ uptake into primary monolayers of smooth muscle cells obtained from pig coronary arteries. The cellular Ca incorporation was analyzed by liquid scintillation. Depolarization was...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Fleckenstein-Grün G,Matyas S,Dumont L

    更新日期:1997-06-01 00:00:00

  • Dietary inulin in mice stimulates Mg2+ absorption and modulates TRPM6 and TRPM7 expression in large intestine and kidney.

    abstract::Complex fermentable carbohydrates, such as inulin-type fructans have been shown to improve Mg2+ absorption in the hindgut and body stores. The mechanisms for this are not well understood. The newly identified transient receptor potential melastatin 6 and 7 (TRPM6 and TRPM7) channels have been shown to function in acti...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Rondón LJ,Rayssiguier Y,Mazur A

    更新日期:2008-12-01 00:00:00

  • Recent data on mitral valve prolapse and magnesium deficit.

    abstract::Idiopathic mitral valve prolapse (IMVP) is a widespread disease. IMVP may be latent, but most patients describe a great variety of symptoms. The clinical pictures of IMVP and of latent tetany are superimposed with regard to Mg deficit. IMVP appears as a late complication of latent tetany due to magnesium deficit (LTMD...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:

    authors: Zeana CD

    更新日期:1988-12-01 00:00:00

  • The COVID-19 pandemic: is there a role for magnesium? Hypotheses and perspectives.

    abstract::More and more studies are accumulating about COVID-19. Some aspects of the pathogenesis of the disease recall events occurring in Mg deficiency, such as a drop of T cells, increased plasma concentration of inflammatory cytokines, and endothelial dysfunction. We hypothesize that a low Mg status, which is rather common,...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2020.0465

    authors: Iotti S,Wolf F,Mazur A,Maier JA

    更新日期:2020-05-01 00:00:00

  • Correlations between feeding type and blood ionized magnesium levels in Japanese preterm infants.

    abstract::Although magnesium (Mg) contents are different between breast milk and formula, few studies have investigated the blood Mg level in breast fed or formula fed preterm infants. We examined the influence of feeding type on serum Mg and whole blood ionized Mg (iMg) levels in preterm infants soon after birth. We included 1...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2019.0444

    authors: Watanabe A,Shoji H,Awaji A,Ikeda N,Ohkawa N,Suganuma H,Kantake M,Shimizu T

    更新日期:2018-11-01 00:00:00

  • Effect of magnesium supplementation containing mineral bishofit (MgCl2 x 6H2O) solution and pyridoxine hydrochloride on erythrocyte magnesium depletion and behaviour of rats after three-month alcoholization.

    abstract::In therapy it is known that the combination of vitamin B6 and magnesium is beneficial in the treatment of several forms of primary magnesium deficiency. The purpose of the present study was to investigate the effect of complex magnesium supplementation containing mineral bishofit solution (MgCl2 x 6H2O) and pyridoxine...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Iezhitsa IN,Onishchenko NV,Churbakova NV,Parshev VV,Petrov VI,Spasov AA

    更新日期:2002-12-01 00:00:00

  • Changes in the haemostatic profile during magnesium deficiency in swine.

    abstract::Epidemiological studies of populations living in areas of low magnesium (Mg) intake have consistently shown a higher cardiovascular morbidity. Several hypotheses have been advanced to explain the cardioprotective properties of magnesium. Few studies, however, have analysed the relation of magnesium to haemostasis. The...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Serebruany VL,Herzog WR,Edenbaum LR,Shustov AR,Gurbel PA

    更新日期:1996-10-01 00:00:00

  • Protein peroxidation, magnesium deficiency and fibromyalgia.

    abstract::Lipid and protein peroxidations were investigated in female patients with magnesium deficit (MD), fibromyalgia (FM) and age matched controls: malondialdehyde and protein carbonyls (PC), as well as serum, leucocyte and erythrocyte magnesium (EMg) were assessed in 20 controls, 25 FM and 16 MD patients. MDA are unchanged...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Eisinger J,Zakarian H,Pouly E,Plantamura A,Ayavou T

    更新日期:1996-12-01 00:00:00

  • Intravenous magnesium sulphate effect on maternal serum and amniotic fluid cytokines levels in preterm labour patients.

    abstract::Our objective was to evaluate the effect of intravenous magnesium sulphate administration to patients with preterm labour on maternal serum and amniotic fluid IL-1beta, IL-6, IL-10 and TNFalpha concentrations. Thirty-six patients at 24-34 weeks of singleton gestation, who presented with contractions (> or = 8 in 60 mi...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Mezad D,Hallak M,Huleihel M,Gortzak-Uzan L,Smolin A,Mazor M

    更新日期:2002-12-01 00:00:00