Posterior reversible encephalopathy syndrome in a patient with hepatitis B induced type 1 membranoproliferative glomerulonephritis.

abstract：:Lecithin:cholesterol acyltransferase (LCAT) is a key enzyme involved in reverse cholesterol transport from the peripheral tissues to the liver. LCAT deficiency, in which this enzyme is congenitally absent, is a genetic disease that impairs the esterification of free cholesterol in the plasma, leading to accumulation o...

journal_title：Clinical and experimental nephrology

authors： Hirashio S,Ueno T,Naito T,Masaki T

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:A close correlation has been shown between tubulointerstitial (TI) injury and the outcome of renal dysfunction, and nuclear factor-kappaB (NFkappaB) has been shown to play a key role in proteinuria-induced TI injury. To explore the molecular mechanisms of the proteinuria-induced TI injury further, we have an...

journal_title：Clinical and experimental nephrology

authors： Takase O,Marumo T,Hishikawa K,Fujita T,Quigg RJ,Hayashi M

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Mortality in the first year of maintenance dialysis is higher than in subsequent years and, within this first year, the risk of death is highest in the first 90 days. Some studies have shown that pre-dialysis education reduces early mortality. Limited data have been published from South Africa regarding earl...

journal_title：Clinical and experimental nephrology

authors： Fabian J,Van Jaarsveld K,Maher HA,Gaylard P

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Although several studies have investigated the relationship between dietary nutrient intake and microalbuminuria, no study of an Asian population has been reported. The present study investigates the relationship between dietary intake and microalbuminuria in a general Japanese population. METHODS:We analyz...

journal_title：Clinical and experimental nephrology

authors： Sato M,Hozawa A,Konta T,Shao L,Otani K,Narimatsu H,Sasaki S,Kato T,Kubota I,Yamashita H,Kayama T,Fukao A

更新日期：2012-02-01 00:00:00

abstract：:Increasing attention has been paid to the relationship of autoantibodies to ribosomal P proteins (anti-P) with lupus nephritis. Several mechanisms of involvement of anti-P in lupus nephritis have been proposed, including cross-reactivity with anti-dsDNA and anti-endothelial cell antibodies (AECA). In addition, it is a...

journal_title：Clinical and experimental nephrology

authors： Hirohata S

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Although neutrophil-to-lymphocyte ratio (NLR) is closely associated with pneumonia in the general population, its relationship is unclear in peritoneal dialysis (PD) patients. METHODS:This is a cohort study consisting of 739 PD patients and dividing into two groups. Kaplan-Meier curves were applied to obser...

journal_title：Clinical and experimental nephrology

authors： Zhang Y,Lai X,Chen Q,Zhan X,Long H,Peng F,Zhang F,Feng X,Zhou Q,Wu X,Liu L,Wang Z,ETNA.,Peng X,Hu K,Wang D,Guo G,Zeng Y,Wen Y,Liang J

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Previous studies reported that children with neural tube defects, but without any history of intrinsic renal diseases, have small kidneys when compared with age-matched standard renal growth. The aim of this study was to investigate the possible causes of small renal size in children with spina bifida by com...

journal_title：Clinical and experimental nephrology

authors： Montaldo P,Montaldo L,Iossa AC,Cennamo M,Caredda E,Del Gado R

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Achieving a normal final adult height (FH) remains a challenge in the field of pediatric kidney transplantation (KTx). To examine the optimal approach to assuring normal FH following KTx, we retrospectively examined the post-transplant growth and FH of pediatric KTx recipients. METHODS:Since the relevant fa...

journal_title：Clinical and experimental nephrology

authors： Fujii H,Chikamoto H,Akioka Y,Hattori M

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Equations for the creatinine-based estimated glomerular filtration rate (eGFR) were recently established for Japanese adults (>18 years old) and children (2-11 years old), respectively, but it is unclear whether eGFR can be as useful as 24-h creatinine clearance (CCr) for assessing renal function in patients...

journal_title：Clinical and experimental nephrology

authors： Inoue N,Watanabe H,Okamura K,Kondo S,Kagami S

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:The Japanese classification of diabetic nephropathy reflects the risks of mortality, cardiovascular events and kidney prognosis and is clinically useful. Furthermore, pathological findings of diabetic nephropathy are useful for predicting prognoses. In this study, we evaluated the characteristics of patholog...

journal_title：Clinical and experimental nephrology

authors： Furuichi K,Shimizu M,Yuzawa Y,Hara A,Toyama T,Kitamura H,Suzuki Y,Sato H,Uesugi N,Ubara Y,Hohino J,Hisano S,Ueda Y,Nishi S,Yokoyama H,Nishino T,Kohagura K,Ogawa D,Mise K,Shibagaki Y,Makino H,Matsuo S,Wada T,

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Low-energy extracorporeal shock wave (SW) improves ventricular function in ischemic cardiomyopathy through the upregulation of vascular endothelial growth factor (VEGF). VEGF is known to play important roles in acute kidney injury (AKI), and the present study investigates the efficacy of SW for AKI by renal ...

journal_title：Clinical and experimental nephrology

authors： Yoshida M,Nakamichi T,Mori T,Ito K,Shimokawa H,Ito S

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:The suitable methods evaluating glomerular filtration rate (GFR) have not been established in patients undergoing radical nephrectomy (RN) or radical nephroureterectomy (RNU) due to urological malignancies in Japan as well as worldwide. METHODS:We examined the relationship between creatinine clearance-based...

journal_title：Clinical and experimental nephrology

authors： Niwa N,Yoshida T,Mizuno R,Kikuchi E,Miyajima A,Hayashi M,Oya M

更新日期：2018-10-01 00:00:00

abstract：:We report a case of a 59-year-old woman who had severe metabolic acidosis and hypokalemia due to an enterovesical fistula. The patient came to our hospital complaining of systemic weakness and numbness of the fingers. She was found to have hyperchloremic metabolic acidosis (arterial bicarbonate, 2.8 mEq/l) and hypokal...

journal_title：Clinical and experimental nephrology

authors： Murakami K,Tomita M,Kawamura N,Hasegawa M,Nabeshima K,Hiki Y,Sugiyama S

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Autosomal dominant polycystic disease (ADPKD) often results in renal failure. Recently, allelic influences of PKD1 mutation types on renal survival were extensively investigated. Here, we analyzed integrated influences of PKD1 mutation types and positions on renal survival. METHODS:We included 338 (82 pedig...

journal_title：Clinical and experimental nephrology

authors： Higashihara E,Horie S,Kinoshita M,Harris PC,Okegawa T,Tanbo M,Hara H,Yamaguchi T,Shigemori K,Kawano H,Miyazaki I,Kaname S,Nutahara K

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Dotinurad, a novel selective urate reabsorption inhibitor (SURI), reduces serum uric acid levels by selectively inhibiting urate transporter 1 (URAT1) for the treatment of hyperuricemia with or without gout. We confirmed the serum uric acid lowering effect and safety of dotinurad. METHODS:This was a confirm...

journal_title：Clinical and experimental nephrology

authors： Hosoya T,Sano T,Sasaki T,Fushimi M,Ohashi T

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Because of the well-established annual urinalysis screening system in Japan, the duration of nephropathy (DN) can be estimated in more than half of all patients with IgA nephropathy (IgAN). Treatment using a combination of tonsillectomy and steroid pulse (TSP) therapy has been reported as an effective method...

journal_title：Clinical and experimental nephrology

authors： Ieiri N,Hotta O,Sato T,Taguma Y

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Creatinine clearance (Ccr) overestimates glomerular filtration rate (GFR) due to the tubular secretion of creatinine. It is known that fractional excretion of creatinine (FE-Cr) increases with decreasing GFR. Association of serum albumin level with the tubular secretion of creatinine was also reported previo...

journal_title：Clinical and experimental nephrology

authors： Horio M,Imai E,Yasuda Y,Watanabe T,Matsuo S

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:School urinary screening has been performed in Japan. METHODS:Ikeda City and Toyono Town introduced, in 2012 and 2013, urinary protein/creatinine (Cr) ratio measurement into the urine-screening protocols designed for students aged between 4 and 15 years. For each student whose urinary protein/Cr ratio was ≥...

journal_title：Clinical and experimental nephrology

authors： Kajiwara N,Hayashi K,Fujiwara M,Nakayama H,Ozaki Y

更新日期：2020-05-01 00:00:00

abstract：:A 33-year-old woman was transferred to our hospital with a 5-month history of taking Chinese herbal medicine containing aristolochic acid. She presented with metabolic acidosis, severe anemia, hypophosphatemia and uric aciduria, and generalized aminoaciduria and glycosuria, features which were consistent with the clin...

journal_title：Clinical and experimental nephrology

authors： Kazama I,Matsubara M,Michimata M,Suzuki M,Hatano R,Sato H,Ito S

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Renal inulin clearance is the gold standard for glomerular filtration rate (GFR), but is compromised by problems of collecting urine samples in children, especially those <6 years of age or with a bladder dysfunction. Therefore, we should utilize the serum creatinine (Cr)-based estimated GFR (eGFR), measurin...

journal_title：Clinical and experimental nephrology

authors： Nagai T,Uemura O,Ishikura K,Ito S,Hataya H,Gotoh Y,Fujita N,Akioka Y,Kaneko T,Honda M

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Tolvaptan slowed the rates of total kidney volume (TKV) growth and renal function decline over a 3-year period in patients with autosomal dominant polycystic kidney disease (ADPKD) enrolled in the Tolvaptan Efficacy and Safety in Management of Autosomal Dominant Polycystic Kidney Disease and Its Outcomes (TE...

journal_title：Clinical and experimental nephrology

authors： Horie S,Muto S,Kawano H,Okada T,Shibasaki Y,Nakajima K,Ibuki T

更新日期：2021-01-20 00:00:00

abstract：:Inflammatory pseudotumour (IPT) is a rare disease of unknown cause that most commonly involves the lung but can occur in almost any site in the body. Occurrence in the kidneys is very rare and bilateral renal involvement even rarer. There are 34 previously reported cases in the English-language medical literature betw...

journal_title：Clinical and experimental nephrology

authors： Li JY,Yong TY,Coleman M,Astill D,Passaris G,Juneja R,Siddins M,Barbara JA

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Although acute kidney injury (AKI) is known as a potential complication of influenza infections, there is limited information concerning the association between influenza and AKI. The aim of this study is to evaluate the incidence, the mortality, and risk factors of AKI in hospitalized patients by seasonal i...

journal_title：Clinical and experimental nephrology

authors： Ishibuchi K,Fukasawa H,Kaneko M,Yasuda H,Furuya R

更新日期：2021-01-04 00:00:00

abstract：BACKGROUND:Sirt1, a mammalian homolog of silent information regulator 2 (Sir2), is the founding member of class III histone deacetylase (HDAC). METHODS:In this study, we examined whether Sirt1 is involved in the modification of acetylated histone H3, acetylated p53 and Werner syndrome protein (WRN), which is stabilize...

journal_title：Clinical and experimental nephrology

authors： Sakao Y,Kato A,Tsuji T,Yasuda H,Togawa A,Fujigaki Y,Kahyo T,Setou M,Hishida A

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:The present study was conducted to clarify the clinical risk factors related to the development of encapsulating peritoneal sclerosis (EPS), which is one of the most serious complications in patients undergoing peritoneal dialysis (PD). METHODS:The records of 78 patients with a history of PD treatment, incl...

journal_title：Clinical and experimental nephrology

authors： Yamamoto R,Otsuka Y,Nakayama M,Maruyama Y,Katoh N,Ikeda M,Yamamoto H,Yokoyama K,Kawaguchi Y,Matsushima M

更新日期：2005-06-01 00:00:00

abstract：:Unique renal histopathological appearances, consisting of podocytic infolding and microstructures in the glomerular basement membrane (GBM) were identified in the renal biopsies from three patients with collagen diseases such as systemic lupus erythematosus (lupus nephritis, class II) and Sjögren's syndrome. In each c...

journal_title：Clinical and experimental nephrology

authors： Sugiyama H,Maruyama M,Morinaga H,Inoue T,Takiue K,Kikumoto Y,Kinomura M,Sada KE,Akagi S,Kitamura S,Maeshima Y,Makino H

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Albuminuria is a biomarker for chronic kidney disease and an independent predictor of cardiovascular and all-cause mortality. A recent meta-analysis concluded that these risks increase with urinary albumin concentration, even when below the microalbuminuria threshold. Thus, minimizing urinary albumin may be ...

journal_title：Clinical and experimental nephrology

authors： Yamamoto-Kabasawa K,Hosojima M,Yata Y,Saito M,Tanaka N,Tanaka J,Tanabe N,Narita I,Arakawa M,Saito A

更新日期：2015-12-01 00:00:00

abstract：:Idiopathic nephrotic syndrome is the most common chronic glomerular disease in children. At least 20 % of children with this syndrome show frequent relapses and/or steroid dependence during or after immunosuppressive therapies, a condition defined as complicated frequently relapsing/steroid-dependent nephrotic syndrom...

journal_title：Clinical and experimental nephrology

authors： Iijima K,Sako M,Nozu K

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Dotinurad is a novel, selective urate reabsorption inhibitor, which reduces serum uric acid levels by inhibiting the urate transporter 1 (URAT1). We compared the pharmacokinetics (PK), pharmacodynamics (PD), and safety of dotinurad in subjects with hepatic impairment and normal hepatic function. METHODS:Thi...

journal_title：Clinical and experimental nephrology

authors： Kumagai Y,Sakaki M,Furihata K,Ito T,Inoue K,Yoshida T,Matsumoto S,Furuno K,Hagino A

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Hyperuricemia is supposed to be an independent risk factor for kidney dysfunction in diabetic patients. We attempted to examine the uric acid-lowering effect and the renoprotective effect of topiroxostat, a selective xanthine oxidoreductase inhibitor, in patients with diabetic nephropathy and hyperuricemia i...

journal_title：Clinical and experimental nephrology

authors： Wada T,Hosoya T,Honda D,Sakamoto R,Narita K,Sasaki T,Okui D,Kimura K

更新日期：2018-08-01 00:00:00