Abstract:
:An 18-year-old woman with catecholaminergic polymorphic ventricular tachycardia (CPVT) underwent pulmonary vein isolation (PVI) because of frequent and inappropriate shocks from an implantable cardioverter defibrillator (ICD) associated with atrial fibrillation (AF) with a rapid ventricular response. While the PVI did not completely suppress the AF induced by an isoproterenol infusion, the Holter monitor recordings demonstrated a major decrease in the clinical episodes of AF and ventricular tachyarrhythmias in association with a reduced high-frequency (HF) component and ratio of the low-frequency (LF) component power to the HF component (LF/HF) after the PVI. The PVI can decrease the substrates that trigger and maintain the AF when it involves a pulmonary vein origin, and may exert an additional effect on the sympathetic nerve input to the heart. The PVI may be an adjunctive therapy for CPVT cases with drug refractory AF causing inappropriate ICD discharges.
journal_name
Heart Vesselsjournal_title
Heart and vesselsauthors
Sumitomo N,Nakamura T,Fukuhara J,Nakai T,Watanabe I,Mugishima H,Hiraoka Mdoi
10.1007/s00380-009-1214-6subject
Has Abstractpub_date
2010-09-01 00:00:00pages
448-52issue
5eissn
0910-8327issn
1615-2573journal_volume
25pub_type
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