Abstract:
:The normal development of elastin fibers in the thoracic aorta was studied in fetal, young, and adult monkeys. Tissue was examined by scanning electron microscopy (SEM) after NaOH treatment and by transmission electron microscopy (TEM). The NaOH treatment of fixed tissues effectively removed collagen fibers and enabled three-dimensional visualization of the elastin fibers. In intact fetal aortae, the internal elastic lamina (IEL) was situated immediately beneath the endothelium. This IEL consisted of superficial, longitudinally arranged bundles of elastin fibrils and an underlying solid sheet containing round fenestrations. In neonates, diffuse intimal thickening was observed. In the young and young-adult monkeys, the aortae exhibited intimal thickening with slender but split IEL. One of the most important findings of this study was that elastin fibers in the intimal thickening, as well as smooth muscle cells, ran in a longitudinal fashion. This was in contrast with the elastic laminae of the media which were mainly oriented circumferentially. Subendothelial elastin fibers in this intimal thickening combined with longitudinally arranged microfibrils which formed close associations with endothelial stress fibers. In some adult monkey aortae with well-developed intimal thickening, a complex meshwork of slender elastin fibers was also found beneath the endothelium. The development of the intimal elastin fibers is discussed in relation to hemodynamic forces.
journal_name
Heart Vesselsjournal_title
Heart and vesselsauthors
Sato F,Shimada T,Kitamura H,Campbell GR,Ogata Jdoi
10.1007/BF01745239subject
Has Abstractpub_date
1994-01-01 00:00:00pages
140-7issue
3eissn
0910-8327issn
1615-2573journal_volume
9pub_type
杂志文章abstract::The hydrostatic pressure (perfusion pressure) of the isovolumic isolated perfused rat heart regulated the hydrodynamics (water movement) of the myocardium. An abrupt (10 s) decrease in hydrostatic pressure caused an immediate decrease in oxygen consumption, left ventricular developed pressure, and wall thickness. Wall...
journal_title:Heart and vessels
pub_type: 杂志文章
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更新日期:1988-01-01 00:00:00
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pub_type: 杂志文章
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journal_title:Heart and vessels
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pub_type: 杂志文章
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journal_title:Heart and vessels
pub_type: 杂志文章
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abstract::Atrial tachyarrhythmias often originate from the superior vena cava (SVC), and right superior (RSPV) and inferior pulmonary veins (RIPV). However, a precise differentiation of those origins is challenging using the standard 12-lead electrocardiogram (ECG) P-wave morphology due to the anatomical proximity. The recently...
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journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s003800200018
更新日期:2002-07-01 00:00:00
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pub_type: 杂志文章
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journal_title:Heart and vessels
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journal_title:Heart and vessels
pub_type: 杂志文章,多中心研究
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更新日期:2016-10-01 00:00:00
abstract::Drug-eluting stents reduce restenosis due to neointimal growth suppression. Considering long-term outcomes, it is both difficult and important to predict drug-eluting stent restenosis. Thus, this study was designed to examine the utility of myocardial fractional flow reserve (FFR) as a predictor of sirolimus-eluting s...
journal_title:Heart and vessels
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journal_title:Heart and vessels
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pub_type: 临床试验,杂志文章
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更新日期:2010-03-01 00:00:00
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journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-006-0971-8
更新日期:2007-09-01 00:00:00
abstract::Peripartum cardiomyopathy (PPCM) is a rare but life-threatening cardiac disorder characterized by maternal systolic heart failure. Although PPCM is a major cause of maternal mortality, little is known about the acute-phase management of PPCM in real-world clinical settings. We retrospectively identified patients hospi...
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更新日期:2017-08-01 00:00:00
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journal_title:Heart and vessels
pub_type: 杂志文章,随机对照试验
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journal_title:Heart and vessels
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更新日期:2013-01-01 00:00:00
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journal_title:Heart and vessels
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journal_title:Heart and vessels
pub_type: 杂志文章
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journal_title:Heart and vessels
pub_type: 杂志文章
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更新日期:2005-11-01 00:00:00
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journal_title:Heart and vessels
pub_type: 杂志文章
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更新日期:1988-01-01 00:00:00
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journal_title:Heart and vessels
pub_type: 杂志文章
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