Ibutilide protects against cardiomyocytes injury via inhibiting endoplasmic reticulum and mitochondrial stress pathways.

abstract：:The timing and amplitude of reflected arterial waves in the ascending aorta were studied by analysis of the aortic pressure waveform and were compared with those derived using wave intensity analysis. Wave intensity analysis considers aortic pressure changes to be the result of forward and backward wavelets carrying e...

journal_title：Heart and vessels

authors： Koh TW,Pepper JR,DeSouza AC,Parker KH

更新日期：1998-01-01 00:00:00

abstract：:In the present study, we investigated whether gallic acid (GA) can induce death in cultured vascular smooth muscle cells (VSMCs), and whether production of the hydroxyl radical (.OH) is involved in the process of GA action. GA killed cultured VSMCs from rat aorta, in a dosc- and time-dependent manner. Cytoplasmic shri...

journal_title：Heart and vessels

authors： Qiu X,Takemura G,Koshiji M,Hayakawa Y,Kanoh M,Maruyama R,Ohno Y,Minatoguchi S,Akao S,Fukuda K,Fujiwara T,Fujiwara H

更新日期：2000-01-01 00:00:00

abstract：:Although the number of pregnancies in women with cardiac disease is increasing worldwide, there are few data concerning their clinical characteristics and peripartum outcomes. Using the Diagnosis Procedure Combination database between 2008 and 2014 in Japan, we retrospectively identified pregnant women who underwent h...

journal_title：Heart and vessels

authors： Isogai T,Matsui H,Tanaka H,Kohyama A,Fushimi K,Yasunaga H

更新日期：2018-08-01 00:00:00

abstract：:Even though drug-coated balloon (DCB) angioplasty has emerged as a treatment option for drug-eluting stent in-stent restenosis (DES-ISR), the most effective treatment strategy for DES-ISR is still under debate. Therefore, we compared long-term clinical outcomes following DCB treatment of DES-ISR with those following 2...

journal_title：Heart and vessels

authors： Kang IS,Shehata I,Shin DH,Kim JS,Kim BK,Ko YG,Choi D,Jang Y,Hong MK

更新日期：2016-09-01 00:00:00

abstract：:Although endothelial progenitor cells (EPCs) are considered to be an essential source of vascular endothelial repair, their bidirectional differentiation determines that they play a double-edged role in the restoration of endothelial injury. In this research, we investigated the effect of Kir2.1 ion channel on the tra...

journal_title：Heart and vessels

authors： Li J,He Y,Bu H,Wang M,Yu J,Li L,Li H,Zhang X,Cui X,Cheng M

更新日期：2020-10-01 00:00:00

abstract：:We investigated the therapeutic principles and strategies to treat sustained ventricular tachycardia (SVT) as five leading medical institutions in the Tokyo area and summarized the present situation of SVT treatment in Japan. Catheter ablation (ABL) has been almost established to be effective in idiopathic ventricular...

journal_title：Heart and vessels

authors： Ogura H,Katoh T,Kasanuki H,Iinuma H,Ozawa Y,Majima S,Hayakawa H

更新日期：1997-01-01 00:00:00

abstract：:An excess of thyroid hormone is known to produce cardiac dysfunction and failure, i.e., thyrotoxic heart. We studied the protective effect of coenzyme Q10 (CoQ10) on the thyrotoxic heart in 29 rabbits. A group treated with 1-thyroxine sodium salt (T4; 167 micrograms/kg) for 3 weeks showed marked decreases in the myoca...

journal_title：Heart and vessels

authors： Kotake C,Ito Y,Yokoyama M,Fukuzaki H

更新日期：1987-01-01 00:00:00

abstract：:In early systole, before the effects of reflected waves from the periphery become significant, the following equation applies: PA - PO = rho cu (1) where PA and PO are the instantaneous and end-diastolic pressures in the ascending aorta, rho the density of blood, c the velocity of the pulse wave in the aorta, and u th...

journal_title：Heart and vessels

authors： Harada Y,Sugawara M,Beppu T,Higashidate M,Nakata S,Imai Y

更新日期：1987-01-01 00:00:00

abstract：:Chronic inflammation has received a great deal of attention due to the role it plays in cardiovascular disease (CVD). The cardio-ankle vascular index (CAVI) has recently been developed to evaluate arterial stiffness. This index is independent of blood pressure at the time that it is measured, making it a better measur...

journal_title：Heart and vessels

authors： Kotani K,Yamada T,Miyamoto M,Kario K,Ishibashi S,Taniguchi N

更新日期：2012-09-01 00:00:00

abstract：:The overall transfer function of a photoplethysmograph (PPG) converting changes in intravascular volume to changes in recorder pen deflection was investigated. The specifications of the apparatus working as a red cell densitometer were assessed in vitro, and it was found that PPG output is a logarithmic function of re...

journal_title：Heart and vessels

authors： Jespersen LT,Pedersen OL

更新日期：1986-01-01 00:00:00

abstract：:The modulation of L-type Ca2+ currents (I(Ca,L)) by the basal activities of G proteins was studied in adult guinea pig ventricular myocytes by whole-cell patch-clamp techniques. With intrapipette guanosine triphosphate (GTP) (100 microM), a specific inhibition of G1 proteins by pertussis toxin (PTX) produced an increa...

journal_title：Heart and vessels

authors： Makita T,Horie M,Xie LH,Okada Y,Sasayama S

更新日期：2000-01-01 00:00:00

abstract：:Activities of daily living (ADL) are maintained in patients with mild cognitive impairment (MCI), but, in patients with cardiovascular disease, ADL may have already declined. MCI combined with cardiac disease may accentuate the decline of ADL in these patients. Because the relationship between MCI and ADL in patients ...

journal_title：Heart and vessels

authors： Ishihara K,Izawa KP,Kitamura M,Shimogai T,Kanejima Y,Morisawa T,Shimizu I

更新日期：2019-12-01 00:00:00

abstract：:Thin-cap fibroatheroma (TCFA) is the most common type of vulnerable plaque and is the precursor of plaque rupture. However, rupture of a TCFA is not the only mechanism underlying thrombus formation or acute coronary syndrome. Although statin therapy changes the composition of coronary artery plaques, the effects of st...

journal_title：Heart and vessels

authors： Nozue T,Yamamoto S,Tohyama S,Fukui K,Umezawa S,Onishi Y,Kunishima T,Sato A,Nozato T,Miyake S,Takeyama Y,Morino Y,Yamauchi T,Muramatsu T,Hibi K,Terashima M,Michishita I

更新日期：2015-01-01 00:00:00

abstract：:To test the therapeutic efficacy of levamisole, 5-week-old DBA/2 mice were inoculated intraperitoneally with 10 plaque-forming units of encephalo-myocarditis virus. Levamisole (2.5 mg/kg/per day) was administered intraperitoneally daily, starting simultaneously with the virus inoculation, in experiment I for 14 days, ...

journal_title：Heart and vessels

authors： Kishimoto C,Takada H,Hiraoka Y,Kurokawa M,Ochiai H

更新日期：1997-01-01 00:00:00

abstract：:Hyperuricemia is common in chronic kidney disease (CKD), but data regarding the relationship between serum uric acid levels and the long-term outcomes of CKD patients have been limited. The present study evaluated the associations between baseline serum uric acid levels with mortality and end-stage renal disease (ESRD...

journal_title：Heart and vessels

authors： Miyaoka T,Mochizuki T,Takei T,Tsuchiya K,Nitta K

更新日期：2014-07-01 00:00:00

abstract：:The inducibility of reentry was compared for four QT patterns in a heart conduction simulation model. Local (L) and gradual (G) QT prolongation models are more susceptible to reentry induction than the no (N) QT prolongation model (reentry induced episodes for N, L, and G numbered 90, 120, and 122, respectively). This...

journal_title：Heart and vessels

authors： Shibata N,Watanabe H,Sakuma I,Kodama I,Niwa R,Fukui Y,Toyama J,Hosoda S

更新日期：1997-01-01 00:00:00

abstract：:We retrospectively analyzed coronary arteriograms in 66 patients with hypertrophic cardiomyopathy (HCM) who underwent coronary arteriography. Four of these patients showed a large conus artery supplying the interventricular septum, and the characteristics of their echocardiograms revealed a marked interventricular sep...

journal_title：Heart and vessels

authors： Sumimoto T,Hamada M,Ohtani T,Shigematsu Y,Fujiwara Y,Sekiya M,Hiwada K

更新日期：1992-01-01 00:00:00

abstract：:Myocardial fibrosis and microvascular dysfunction are key determinants of outcome in heart failure (HF); we examined their relationship in patients with HF. Our study included 61 consecutive patients with HF but without coronary stenosis. All underwent gadolinium-enhanced cardiac magnetic resonance to evaluate late ga...

journal_title：Heart and vessels

authors： Uemura T,Yamamuro M,Kaikita K,Takashio S,Utsunomiya D,Hirakawa K,Nakayama M,Sakamoto K,Yamamoto E,Tsujita K,Kojima S,Hokimoto S,Yamashita Y,Ogawa H

更新日期：2016-12-01 00:00:00

abstract：:This study assesses the global left ventricular function and volumes using dual-source computed tomography (DSCT) with improved temporal resolution (83 ms) by use of a semi-automatic software tool in comparison to invasive angiography (IVA). One hundred patients scheduled for invasive coronary angiography because of s...

journal_title：Heart and vessels

authors： Drosch T,Tsiflikas I,Brodoefel H,Heuschmid M,Reimann A,Thomas C,Ketelsen D,Wurster D,Schroeder S,Burgstahler C

更新日期：2010-01-01 00:00:00

abstract：:Atrial fibrillation (AF) is the most common arrhythmia, characterized by a lack of atrial contraction and an irregular ventricular rhythm. We assessed the effect of fibrillatory wave amplitude on coronary blood flow in patients with AF using the thrombolysis in myocardial infarction (TIMI) frame count. Sixty-one patie...

journal_title：Heart and vessels

authors： Sumimoto Y,Kurisu S,Hitta K,Ikenaga H,Ishibashi K,Fukuda Y,Nakano Y,Kihara Y

更新日期：2018-07-01 00:00:00

abstract：:Taurine (2-aminoethanesulfonic acid) is a potent antioxidant and inhibits cell apoptosis in ischemic reperfusion injury. In this study we evaluated whether addition of taurine to St. Thomas' cardioplegic solution enhances its myocardial protective effects in prolonged hypothermic heart preservation in rats. Hearts iso...

journal_title：Heart and vessels

authors： Oriyanhan W,Yamazaki K,Miwa S,Takaba K,Ikeda T,Komeda M

更新日期：2005-11-01 00:00:00

abstract：:The purpose of this study was to investigate the use of hepatocyte growth factor as a biochemical marker for acute myocardial infarction. Several biochemical markers are used for noninvasive detection of acute myocardial infarction. However, hepatocyte growth factor has not been used previously for this purpose. We me...

journal_title：Heart and vessels

authors： Sato T,Yoshinouchi T,Sakamoto T,Fujieda H,Murao S,Sato H,Kobayashi H,Ohe T

更新日期：1997-01-01 00:00:00

abstract：:The objective of this study is to determine whether pentraxin-3 (PTX-3) is clinically a biomarker of inflammation, a player in anti-inflammation, or both with regard to coronary atherosclerosis, we compared levels of PTX-3 with levels of adiponectin in addition to high-sensitivity C-reactive protein (hs-CRP). We enrol...

journal_title：Heart and vessels

authors： Nakamura A,Miura S,Shiga Y,Norimatsu K,Miyase Y,Suematsu Y,Mitsutake R,Saku K

更新日期：2015-11-01 00:00:00

abstract：:Peripheral artery disease (PAD) is a risk factor for the development of heart failure and mortality. The serum levels of carboxy-terminal telopeptide of type I collagen (I-CTP), a marker for collagen degradation derived from the extracellular matrix of vascular and myocardial tissue, is reportedly a useful marker for ...

journal_title：Heart and vessels

authors： Otaki Y,Watanabe T,Takahashi H,Yamaura G,Nishiyama S,Arimoto T,Shishido T,Miyamoto T,Kubota I

更新日期：2017-02-01 00:00:00

abstract：:Soluble urokinase-type plasminogen activator receptor (suPAR) is a membrane-binding protein that is released into the blood stream by immune activation. Recent reports suggest that circulating suPAR levels are associated with adverse cardiovascular outcomes. Exercise tolerance is an independent predictor of prognosis ...

journal_title：Heart and vessels

authors： Ishikawa H,Izumiya Y,Shibata A,Ichikawa Y,Yamaguchi T,Yamaguchi Y,Kitada R,Iwata S,Ehara S,Tomita S,Hanatani A,Yoshiyama M

更新日期：2020-05-01 00:00:00

abstract：:Vector flow mapping (VFM) is a novel echocardiographic technology that shows blood flow vectors and vortexes, enabled the hydrokinetic evaluation of hemodynamics within the left ventricle. VFM provides several unique parameters: circulation, vorticity, vortex area, and energy loss. The present study aims to reveal a r...

journal_title：Heart and vessels

authors： Goya S,Wada T,Shimada K,Hirao D,Tanaka R

更新日期：2018-05-01 00:00:00

abstract：:A 5-year-old girl developed cardiopulmonary arrest after crying. From the electrocardiogram and echocardiography, a left ventricular noncompaction (LVNC) with long QT syndrome (LQT) was suspected as the cause of the cardiopulmonary arrest, and treatment with a β-blocker and a calcium antagonist was then begun. A genet...

journal_title：Heart and vessels

authors： Nakashima K,Kusakawa I,Yamamoto T,Hirabayashi S,Hosoya R,Shimizu W,Sumitomo N

更新日期：2013-01-01 00:00:00

abstract：:The relationship between body mass index (BMI) and the prognosis of elderly patients with atrial fibrillation (AF) is unknown. We aimed to examine the association of body weight with the clinical outcomes among Japanese elderly patients with a history of documented AF. This observational study of AF patients from an o...

journal_title：Heart and vessels

authors： Yanagisawa S,Inden Y,Yoshida N,Kato H,Miyoshi-Fujii A,Mizutani Y,Ito T,Kamikubo Y,Kanzaki Y,Hirai M,Murohara T

更新日期：2016-09-01 00:00:00

abstract：:First-generation drug-eluting stents (DES) demonstrated delay in vascular healing and increase in incidence of late and very late stent thrombosis compared with bare-metal stents (BMS). Second-generation DES, however, have shown a reduction of late and very late stent thrombosis compared with first-generation DES. Thu...

journal_title：Heart and vessels

authors： Yano H,Horinaka S,Ishikawa M,Ishimitsu T

更新日期：2016-10-01 00:00:00

abstract：:Previous studies suggested that sleep-disordered breathing was associated with cardiovascular diseases such as heart failure (HF). Recently, algorithms of cardiac implantable electronic devices (CIEDs) have been developed to detect advanced sleep apnea (SA); the Apnea Scan (AP Scan) being an example. The purpose of th...

journal_title：Heart and vessels

authors： Wakabayashi Y,Koyama T,Kurihara K,Kobayashi M,Ichikawa T,Abe H

更新日期：2020-06-01 00:00:00