A left ventricular noncompaction in a patient with long QT syndrome caused by a KCNQ1 mutation: a case report.

Abstract:

:A 5-year-old girl developed cardiopulmonary arrest after crying. From the electrocardiogram and echocardiography, a left ventricular noncompaction (LVNC) with long QT syndrome (LQT) was suspected as the cause of the cardiopulmonary arrest, and treatment with a β-blocker and a calcium antagonist was then begun. A genetic screening of LQT-related genes revealed a previously reported heterozygous KCNQ1 mutation. The association of LVNC and LQT is an extremely rare condition, and long-term treatment based on the characteristics of both disorders is required. Also, the association of cardiomyopathy and LQT could become a new clinical entity in the future.

journal_name

Heart Vessels

journal_title

Heart and vessels

authors

Nakashima K,Kusakawa I,Yamamoto T,Hirabayashi S,Hosoya R,Shimizu W,Sumitomo N

doi

10.1007/s00380-012-0235-8

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

126-9

issue

1

eissn

0910-8327

issn

1615-2573

journal_volume

28

pub_type

杂志文章