Earliest pulmonary vein potential-guided cryoballoon ablation for atrial fibrillation.

Abstract:

:No studies have evaluated both the time-to-isolation (TTI) and the sequence of pulmonary vein (PV) potentials in cryoballoon ablation (CBA) for atrial fibrillation (AF). This study aimed to prospectively evaluate the acute results of pulmonary vein isolation (PVI) using a novel CBA technique-the earliest potential (EP) of PV-guided CBA-in paroxysmal AF. We pressed a balloon against the earliest PV potential site during PVI when TTI could not be achieved within 60 s (EP-guided CBA group). We compared 32 patients consecutively treated by EP-guided CBA to 32 patients treated without pressing the balloon against the EP site (conventional CBA group). The cryoapplication protocol was the same, except with regard to the pressing of the balloon. All 256 PVs (EP-guided CBA group, 128 PVs; conventional CBA group, 128 PVs) were isolated successfully. The TTI observation rate was similar in both groups. Compared with conventional CBA, EP-guided CBA was associated with a lower non-success rate of TTI ≤ 90 s (9% vs. 26%; P = 0.040) and shorter left atrial dwell time (38 ± 9 vs. 46 ± 19 min; P = 0.036), total procedure time (76 ± 15 vs. 87 ± 23 min; P = 0.043), and fluoroscopy time (23 ± 8 vs. 30 ± 11 min; P = 0.006). This novel EP-guided CBA approach may help facilitate the ablation procedure.

journal_name

Heart Vessels

journal_title

Heart and vessels

authors

Mizutani Y,Kanashiro M,Makino Y,Satake A,Suzuki W,Kurobe M,Mizutani K,Ichimiya H,Uchida Y,Watanabe J,Ichimiya S,Inden Y,Murohara T

doi

10.1007/s00380-019-01471-5

subject

Has Abstract

pub_date

2020-02-01 00:00:00

pages

232-238

issue

2

eissn

0910-8327

issn

1615-2573

pii

10.1007/s00380-019-01471-5

journal_volume

35

pub_type

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