Abstract:
:In this study, coronary diagnostic parameters, pressure drop coefficient (CDP: ratio of trans-stenotic pressure drop to distal dynamic pressure), and lesion flow coefficient (LFC: ratio of % area stenosis (%AS) to the CDP at throat region), were evaluated to distinguish levels of %AS under varying contractility conditions, in the presence of microvascular disease (MVD). In 10 pigs, %AS and MVD were created using angioplasty balloons and 90-μm microspheres, respectively. Simultaneous measurements of pressure drop, left ventricular pressure (p), and velocity were obtained. Contractility was calculated as (dp/dt)max, categorized into low contractility <900 mmHg/s and high contractility >900 mmHg/s, and in each group, compared between %AS <50 and >50 using analysis of variance. In the presence of MVD, between the %AS <50 and >50 groups, values of CDP (71 ± 1.4 and 121 ± 1.3) and LFC (0.10 ± 0.04 and 0.19 ± 0.04) were significantly different (P < 0.05), under low-contractility conditions. A similar %AS trend was observed under high-contractility conditions (CDP: 18 ± 1.4 and 91 ± 1.4; LFC: 0.08 ± 0.04 and 0.25 ± 0.04). Under MVD conditions, similar to fractional flow reserve, CDP and LFC were not influenced by contractility.
journal_name
Heart Vesselsjournal_title
Heart and vesselsauthors
Peelukhana SV,Kolli KK,Leesar MA,Effat MA,Helmy TA,Arif I,Schneeberger EW,Succop P,Banerjee RKdoi
10.1007/s00380-013-0355-9subject
Has Abstractpub_date
2014-01-01 00:00:00pages
97-109issue
1eissn
0910-8327issn
1615-2573journal_volume
29pub_type
杂志文章abstract::The inducibility of reentry was compared for four QT patterns in a heart conduction simulation model. Local (L) and gradual (G) QT prolongation models are more susceptible to reentry induction than the no (N) QT prolongation model (reentry induced episodes for N, L, and G numbered 90, 120, and 122, respectively). This...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:
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journal_title:Heart and vessels
pub_type: 临床试验,杂志文章,随机对照试验
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doi:10.1007/s00380-017-1093-1
更新日期:2018-05-01 00:00:00
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journal_title:Heart and vessels
pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1007/s00380-006-0935-z
更新日期:2007-01-01 00:00:00
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journal_title:Heart and vessels
pub_type: 杂志文章
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更新日期:1996-01-01 00:00:00
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journal_title:Heart and vessels
pub_type: 杂志文章,随机对照试验
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更新日期:2014-05-01 00:00:00
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journal_title:Heart and vessels
pub_type: 杂志文章
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更新日期:1993-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:1995-01-01 00:00:00
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journal_title:Heart and vessels
pub_type: 杂志文章
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更新日期:2017-02-01 00:00:00
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journal_title:Heart and vessels
pub_type: 杂志文章,多中心研究
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更新日期:2009-11-01 00:00:00
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journal_title:Heart and vessels
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更新日期:2020-04-01 00:00:00
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更新日期:2016-12-01 00:00:00
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journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/BF02059969
更新日期:1986-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s00380-017-1017-0
更新日期:2017-12-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2019-09-01 00:00:00
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journal_title:Heart and vessels
pub_type: 杂志文章
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journal_title:Heart and vessels
pub_type: 杂志文章
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更新日期:2020-09-01 00:00:00
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pub_type: 杂志文章
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更新日期:2005-02-01 00:00:00
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更新日期:2005-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:2004-03-01 00:00:00
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journal_title:Heart and vessels
pub_type: 杂志文章
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更新日期:2020-03-01 00:00:00
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journal_title:Heart and vessels
pub_type: 杂志文章
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更新日期:1997-01-01 00:00:00
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更新日期:2021-01-23 00:00:00
abstract::We retrospectively analyzed coronary arteriograms in 66 patients with hypertrophic cardiomyopathy (HCM) who underwent coronary arteriography. Four of these patients showed a large conus artery supplying the interventricular septum, and the characteristics of their echocardiograms revealed a marked interventricular sep...
journal_title:Heart and vessels
pub_type: 杂志文章
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更新日期:1992-01-01 00:00:00