当前位置： SCI文献检索 > HUMAN IMMUNOLOGY期刊下所有文献 > FcεRI levels and frequencies of peripheral blood dendritic cell populations in allergic rhinitis.

FcεRI levels and frequencies of peripheral blood dendritic cell populations in allergic rhinitis.

Abstract：

:The dendritic cell (DC) lineage encompasses a diverse population of cells with unique subtype-specific functions. In peripheral blood, four DC subsets have been identified based on their distinct expression of CD1c, CD141, CD16, and CD123, and these subpopulations exhibit functional properties in immune responses. However, their respective roles in allergic diseases, such as rhinitis, are unclear. In this study, we have performed comparative assessments of DC subset frequencies and investigated their FcεRI expression levels in patients with allergic rhinitis. We demonstrate that the frequencies of CD1c+ and CD141+ DCs are elevated in grass pollen-allergic subjects compared with healthy controls, irrespectively of allergen stimulation. Among the DC subsets, CD1c+ DCs expressed the highest levels of FcεRI mRNA, and a large proportion expressed surface FcεRI. Furthermore, the FcεRI expression levels were augmented upon allergen challenge. Thus our data suggest that CD1c+ DCs influence allergen-specific immune responses. Research on their functional properties in allergy is warranted for development of future immunotherapies targeting specialized DC subsets.

journal_name

Hum Immunol

journal_title

Human immunology

authors

Lundberg K,Greiff L,Borrebaeck CA,Lindstedt M

doi

10.1016/j.humimm.2010.07.008

subject

Has Abstract

pub_date

2010-10-01 00:00:00

pages

931-3

issue

10

eissn

0198-8859

issn

1879-1166

pii

S0198-8859(10)00443-X

journal_volume

71

pub_type

杂志文章

相关文献

HUMAN IMMUNOLOGY文献大全
  • HLA class II genotypic frequencies in atopic asthma: association of DRB1*01-DQB1*0501 genotype with Artemisia vulgaris allergic asthma.

    abstract：:Different human leukocyte antigen (HLA) class II alleles have been associated with the development of atopic asthma. To determine whether HLA class II alleles are associated with atopic asthma in a population from southeast Spain (Murcia region), 213 atopic asthmatic patients and 150 controls were selected for HLA typ...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/s0198-8859(03)00109-5

    authors： Torío A,Sánchez-Guerrero I,Muro M,Villar LM,Minguela A,Marín L,Moya-Quiles MR,Montes-Ares O,Pagán J,Alvarez-López MR

    更新日期：2003-08-01 00:00:00

  • HLA-class I-specific inhibitory receptors in HIV-1 infection.

    abstract：:One of the most characteristic and, at the same time, puzzling features of the cellular immune response towards HIV-1 is represented by an early vigorous HIV-specific CD8+ CTL response that does not prevent disease progression in the vast majority of patients. In this context, there is a striking mismatch over the cou...

    journal_title：Human immunology

    pub_type： 杂志文章,评审

    doi：10.1016/s0198-8859(99)00169-x

    authors： De Maria A,Moretta L

    更新日期：2000-01-01 00:00:00

  • Association of LRP5, TCF7L2, and GCG variants and type 2 diabetes mellitus as well as fasting plasma glucose and lipid metabolism indexes.

    abstract：:Recent data puts WNT signaling pathway in a pivotal role in regulating pancreas development as well as islet function, insulin production and secretion. The key effectors in the WNT signaling pathway are low-density lipoprotein receptor-related protein 5 (LRP5), transcription factor 7-like 2 (TCF7L2), and downstream-r...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2015.03.005

    authors： Wang J,Yan G,Zhang J,Gao K,Zhang M,Li L,Wang Y,Wang Q,Zhai Y,You H,Ren Y,Wang B,Hu D

    更新日期：2015-05-01 00:00:00

  • Association of osteopontin regulatory polymorphisms with systemic sclerosis.

    abstract：:To test the involvement of osteopontin gene (OPN) in systemic sclerosis (SSc) susceptibility, two OPN single nucleotide polymorphisms previously reported to be associated with systemic lupus erythematosus, namely -156G/GG (proximal promoter) and +1239A/C (3' untranslated region (UTR)), were tested in 357 Italian patie...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2011.06.009

    authors： Barizzone N,Marchini M,Cappiello F,Chiocchetti A,Orilieri E,Ferrante D,Corrado L,Mellone S,Scorza R,Dianzani U,D'Alfonso S

    更新日期：2011-10-01 00:00:00

  • Association of HLA-DR and HLA-DQ genes with susceptibility to pulmonary tuberculosis in Koreans: preliminary evidence of associations with drug resistance, disease severity, and disease recurrence.

    abstract：:Only 10% of persons infected with Mycobacterium tuberculosis develop clinical tuberculosis (TB), indicating the existence of host genetic factors regulating disease expression. We investigated the association of human leukocyte antigen (HLA) class II genes with the susceptibility to pulmonary TB in Koreans, with speci...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2005.08.242

    authors： Kim HS,Park MH,Song EY,Park H,Kwon SY,Han SK,Shim YS

    更新日期：2005-10-01 00:00:00

  • Elevated pretransplantation soluble CD30 is associated with decreased early allograft function after human lung transplantation.

    abstract：:Early allograft function after lung transplantation is variable. Clinical criteria have limited predictive value for early graft function. Recipient immunologic state before LTx may affect early lung function. We investigated the association between pretransplantation soluble CD30 (sCD30), a marker of Th2-type T-cell ...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2008.12.005

    authors： Shah AS,Leffell MS,Lucas D,Zachary AA

    更新日期：2009-02-01 00:00:00

  • Characterization of human cardiac infiltrating cells posttransplantation: II. CD4+ cloned T-cell lines with "anti-idiotype"-like reactivity.

    abstract：:CD4+ T cells were cultured from posttransplant cardiac biopsies placed on irradiated feeder cells of autologous cloned donor major histocompatibility complex class II-specific T-cell lines cultured and grown from previous biopsies. Fourteen of the CD4+ T-cell cultures were expanded and cloned using the same feeder cel...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(90)90011-d

    authors： Wang YC,Kanter K,Lattouf O,Rodey GE,Sell KW,Ansari AA

    更新日期：1990-06-01 00:00:00

  • Potential influence of interleukin-1 haplotype IL-1 beta-511*T-IL-1RN*1 in conferring low risk to middle third location of esophageal cancer: a case-control study.

    abstract：:Interleukin (IL)-1 gene polymorphisms affect several inflammatory diseases, including cancer. Therefore, we studied genetic association of biallelic (-511C>T) polymorphism of IL-1 beta and 86-bp VNTR polymorphism of IL-1RN in 159 patients with esophageal cancer (EC) and 194 age- and gender-matched healthy controls. Ge...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2008.01.012

    authors： Upadhyay R,Jain M,Kumar S,Ghoshal UC,Mittal B

    更新日期：2008-03-01 00:00:00

  • Conversion of a human immunodeficiency virus cytotoxic T lymphocyte epitope into a high affinity HLA-Cw3 ligand.

    abstract：:To elucidate the residues important for the binding of peptides to HLA-Cw3, a substitutional analysis of two HLA-Cw*0304-binding peptides was performed. The optimal registry and length for a Cw3-restricted epitope from HIV-1 p24gag was determined to be a nonamer, p24gag 144-152. Substituted analogs of this nonamer pep...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/s0198-8859(98)00053-6

    authors： Zarling AL,Lee DR

    更新日期：1998-08-01 00:00:00

  • Analysis of genes within the HLA region affecting susceptibility to ulcerative colitis.

    abstract：:To clarify the molecular relationship between HLA loci and ulcerative colitis (UC) in Japanese patients, we performed HLA-DP genotyping by the PCR-RFLP method and studied tumor necrosis factor beta-chain genetic polymorphism by Southern hybridization, in addition to conventional serologic typing. Significant increase ...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(93)90113-f

    authors： Sugimura K,Asakura H,Mizuki N,Inoue M,Hibi T,Yagita A,Tsuji K,Inoko H

    更新日期：1993-02-01 00:00:00

  • Use of a murine T-cell hybridoma expressing human T-cell receptor alpha- and beta-gene products as a tool for the production of human T-cell receptor-specific monoclonal antibodies.

    abstract：:We describe the production of mouse monoclonal antibodies specific for the human TcR using as the immunogen transfected murine T-cell hybridoma cells coexpressing mouse CD3 with human Jurkat TcR alpha and beta chains. The shortage of monoclonal antibodies (mAbs) specific for the human TcR-V alpha and V beta families r...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(92)90098-8

    authors： Zumla A,McCormack A,George A,Batchelor R,Lechler R

    更新日期：1992-11-01 00:00:00

  • CD3+CD20+ T cells and their roles in human diseases.

    abstract：:CD3+CD20+ T cells are a population of CD3+ T cells co-expressing CD20 that make up to ∼3-5% of the CD3+ T-cell compartment in the peripheral blood of human beings. In healthy individuals, CD3+CD20+ T cells are heterogeneous for containing a lower proportion of CD4+ cells, but produce higher levels of IL-17A and/or IFN...

    journal_title：Human immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.humimm.2019.01.001

    authors： Chen Q,Yuan S,Sun H,Peng L

    更新日期：2019-03-01 00:00:00

  • Expression of endothelial intercellular adhesion molecule-1 is determined by genotype: effects on efficiency of leukocyte adhesion to human endothelial cells.

    abstract：:Two biallelic polymorphisms, previously described in the human intercellular adhesion molecule (ICAM)-1 gene at codon 241 (glycine [G] to arginine [R] substitution) and codon 469 (glutamic acid [E] to lysine [K] substitution) have been associated with a number of diseases including myocardial infarction, transplant re...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2007.12.004

    authors： Holder AL,Wolf S,Walshe C,Pandya P,Stanford RE,Smith JD,Rose ML,Lawson C

    更新日期：2008-02-01 00:00:00

  • Genetic mapping of the hemochromatosis locus on chromosome six.

    abstract：:The purpose of this paper is to report a pedigree with hereditary hemochromatosis in which a recombination between the HLA-A and B loci occurred. Both the maternal and paternal HLA-A3, B7 haplotypes were carrying an allele for hemochromatosis. The A3, B12 haplotype of the proband was a recombinant of the maternal A3, ...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(80)90005-1

    authors： Edwards CQ,Cartwright GE,Skolnick MH,Amos DB

    更新日期：1980-07-01 00:00:00

  • Ancestry markers from the human chromosome 6: Alu repeats from the MHC in autochthonous Basques.

    abstract：:Polymorphic Alu insertions from the MHC class I region were analyzed in 215 autochthonous Basques from Guipuzcoa and Navarre provinces, with the aim of contributing new MHC Alu data in European ancestry populations. We also seek to assess both the genetic position of native Basques among worldwide samples and the effi...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2012.04.010

    authors： García-Obregón S,Alfonso-Sánchez MA,Pérez-Miranda AM,Gómez-Pérez L,de Parcorbo MM,Peña JA

    更新日期：2012-07-01 00:00:00

  • A murine monoclonal antibody (928) recognizing a new epitope formed with a combination of HLA-DPA1*0201 and DPB1*0301 gene products.

    abstract：:A murine monoclonal antibody (mAb), 928, that recognizes a cell surface antigen (928 Ag) on a human Epstein-Barr virus-transformed fetal liver-derived lymphoid progenitor cell line (FL4.4) was generated. The 928 mAb reacted with only FL4.4; it did not react with any other 57 cell lines tested. Two color flowcytometry ...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/s0198-8859(97)00143-2

    authors： Kishi H,Okumura A,Tong JJ,Sugiyama E,Matsuno H,Minowada J,Kanai T,Nishimura Y,Muraguchi A

    更新日期：1997-08-01 00:00:00

  • Multidrug resistance activity in human lymphocytes.

    abstract：:The multidrug resistance gene (mdr1) is a member of the recently described ATP binding cassette (ABC) superfamily of transporters. Family members include: (1) the cystic fibrosis transmembrane conductance regulator gene; (2) the hlyB gene of bacteria, and (3) the histocompatibility antigen modifier (HAM) gene. The lev...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(91)90110-u

    authors： Coon JS,Wang YZ,Bines SD,Markham PN,Chong AS,Gebel HM

    更新日期：1991-10-01 00:00:00

  • Variable clinical phenotypes of X-linked lymphoproliferative syndrome in China: Report of five cases with three novel mutations and review of the literature.

    abstract：BACKGROUND:X-linked lymphoproliferative disease (XLP) is a rare life-threatening syndrome. Rapid recognition and definitive diagnosis are critical to improve the prognosis and survival of patients with XLP. Nowadays, little is known about patients with XLP in China. METHODS:We report the characterization of five Chine...

    journal_title：Human immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.humimm.2016.06.005

    authors： Jin YY,Zhou W,Tian ZQ,Chen TX

    更新日期：2016-08-01 00:00:00

  • Lymphocytes induce enhanced expression of HLA class I antigens on cytomegalovirus-infected syngeneic human endothelial cells.

    abstract：:Human cytomegalovirus (HCMV) infection has been associated with enhanced expression of HLA antigens on the endothelium and with cellular infiltrates within the graft following human organ transplantation. We investigated the interactions between human cytomegalovirus-infected cultured endothelial cells and cocultured ...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(95)00095-x

    authors： Scholz M,Blaheta RA,Cinatl J,Encke A,Doerr HW,Markus BH

    更新日期：1995-11-01 00:00:00

  • A 70 kDa MHC class I associated protein (MAP-70) identified as a receptor molecule for Coxsackievirus A9 cell attachment.

    abstract：:One of the major categories of disease-causing micro-organisms are viruses. New studies on many different viruses have shown that virus attachment and cell entry is often a multistep process, requiring many interactions between the virus and cell surface molecules. In this study, we have attempted to identify the cell...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/s0198-8859(00)00151-8

    authors： Triantafilou M,Triantafilou K,Wilson KM

    更新日期：2000-09-01 00:00:00

  • Role of galectin-3 in the pathogenesis of bladder transitional cell carcinoma.

    abstract：:Galectins constitute an evolutionary conserved family that binds to β-galactosides. There is growing evidence that galectins are implicated in essential biological processes such as cellular communication, inflammation, differentiation and apoptosis. Galectin-3 is one of the best-known galectins, which is found in ver...

    journal_title：Human immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.humimm.2015.09.036

    authors： Zeinali M,Adelinik A,Papian S,Khorramdelazad H,Abedinzadeh M

    更新日期：2015-10-01 00:00:00

  • Effect of delayed graft function in hypersensitized kidney transplant recipients.

    abstract：:There is increased evidence about the deleterious effect of delayed graft function (DGF) in both short- and long-term kidney graft outcome. Among the mechanisms involved in the production of DGF, immune factors play a role, especially in the level of hypersensitization. From the 1389 patients transplanted at our hospi...

    journal_title：Human immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.humimm.2005.01.026

    authors： López-Hoyos M,Fernández-Fresnedo G,Rodrigo E,Ruiz JC,Arias M

    更新日期：2005-04-01 00:00:00

  • Interleukin 6 -174G>C polymorphism and cancer risk: meta-analysis reveals a site dependent differential influence in Ancestral North Indians.

    abstract：:In our earlier studies, single nucleotide polymorphisms (SNPs) associated with anti-inflammatory cytokines were found to influence risk for breast cancer in western Indian women. Analysis of Interleukin 6 (IL-6) -174G>C polymorphism in this cohort (patients = 182; controls = 236) suggested a protective role for IL-6 -...

    journal_title：Human immunology

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.humimm.2014.06.018

    authors： Joshi N,Kannan S,Kotian N,Bhat S,Kale M,Hake S

    更新日期：2014-08-01 00:00:00

  • Interleukin-1RN gene polymorphisms in elderly patients with rheumatic inflammatory chronic conditions: Association of IL-1RN*2/2 genotype with polymyalgia rheumatica.

    abstract：:The objective of this study was to investigate whether there is an association between IL1RN polymorphism and disease susceptibility for three age-related inflammatory conditions: polymyalgia rheumatica (PMR), giant cell arteritis (GCA), and elderly-onset rheumatoid arthritis (EORA). A tandem-repeat polymorphism withi...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2008.10.011

    authors： Alvarez-Rodriguez L,Carrasco-Marin E,Lopez-Hoyos M,Mata C,Fernandez-Prieto L,Ruiz-Soto M,Calvo J,Rodriguez-Valverde V,Ruiz T,Blanco R,Corrales A,Martinez-Taboada VM

    更新日期：2009-01-01 00:00:00

  • Identification of the amino acid residues contributing to monoclonal antibody-defined DQw1 epitopes.

    abstract：:The reactivity of monoclonal antibodies (mAbs) R1, S1, and S5, shown previously to recognize polymorphic epitopes on HLA-DQ molecules, have been found to correlate with the presence of certain DQB1 alleles. mAb S5 reacts with cells expressing DQB1*0503, 0601, 0602, 0603, or 0604 alleles while R1 and S1 react with all ...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(91)90009-x

    authors： Nordwig H,Kwok WW,Johnson JP

    更新日期：1991-06-01 00:00:00

  • A comprehensive polymerase chain reaction-oligonucleotide typing system for the HLA class I A locus.

    abstract：:A comprehensive system for genetic typing of the HLA class I A locus is described, based on PCR amplification and typing with nonradioactively labeled SSO probes. Exons 1-3 of the A locus are amplified and typing is performed with a set of 30 nonradioactively labeled oligonucleotide probes. This system resolves 34 of ...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(94)90018-3

    authors： Allen M,Liu L,Gyllensten U

    更新日期：1994-05-01 00:00:00

  • Cell culture density modulates the incorporation of HLA antigens by enveloped viruses.

    abstract：:Uninfected, as well as feline leukemia virus (FeLV) infected human cells cultured under high cell density conditions undergo changes in the expression of major histocompatibility complex (MHC) antigens, as determined by indirect trace binding radio immunoassay (RIA) using monoclonal anti-HLA antibodies and by decrease...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/s0198-8859(83)80006-8

    authors： Azocar J,Essex M,Yunis EJ

    更新日期：1983-06-01 00:00:00

  • TLR4 upregulation underpins airway neutrophilia in smokers with chronic obstructive pulmonary disease and acute respiratory failure.

    abstract：:Activation of Toll-like receptors (TLR) seems to be involved in the pathogenesis of chronic obstructive pulmonary disease (COPD). Upon TLR activation the release of defensins, including human beta defensin 2 (HBD-2), may occur. In this study, we explored the innate responses in patients with respiratory failure, with ...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2010.09.009

    authors： Pace E,Giarratano A,Ferraro M,Bruno A,Siena L,Mangione S,Johnson M,Gjomarkaj M

    更新日期：2011-01-01 00:00:00

  • Differential effects of a common splice site polymorphism on the generation of OAS1 variants in human bronchial epithelial cells.

    abstract：:The 2',5'-oligoadenylate synthetase 1 (OAS1) is one of the major interferon-inducible proteins and a critical component of the host defense system against viral infection. A single nucleotide polymorphism (SNP), rs10774671, presumably responsible for alternate splicing of this gene, has frequently been associated with...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2012.11.011

    authors： Noguchi S,Hamano E,Matsushita I,Hijikata M,Ito H,Nagase T,Keicho N

    更新日期：2013-03-01 00:00:00

  • Monoclonal and xenoantibodies specific for HLA-DR inhibit primary responses to HLA-D but fail to inhibit secondary proliferative (PLT) responses to allogeneic cells.

    abstract：:Monoclonal antibodies (DA-2 and CA-2) and xenoantisera (rabbit anti-human, p23,30) specific for HLA-DR framework determinants were added to primary and secondary mixed lymphocyte cultures. Although such antisera were shown to inhibit primary MLC, primed lymphocytes were much less sensitive to the blocking effects of t...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(81)90050-1

    authors： Eckels DD,Woody JN,Hartzman RJ

    更新日期：1981-10-01 00:00:00