当前位置： SCI文献检索 > HUMAN IMMUNOLOGY期刊下所有文献 > Monoclonal and xenoantibodies specific for HLA-DR inhibit primary responses to HLA-D but fail to inhibit secondary proliferative (PLT) responses to allogeneic cells.

Monoclonal and xenoantibodies specific for HLA-DR inhibit primary responses to HLA-D but fail to inhibit secondary proliferative (PLT) responses to allogeneic cells.

Abstract：

:Monoclonal antibodies (DA-2 and CA-2) and xenoantisera (rabbit anti-human, p23,30) specific for HLA-DR framework determinants were added to primary and secondary mixed lymphocyte cultures. Although such antisera were shown to inhibit primary MLC, primed lymphocytes were much less sensitive to the blocking effects of these antibodies. In the studies shown here, the concentration of antibody required to inhibit primary MLC reactions was 0.1-1.5 micrograms/ml).

journal_name

Hum Immunol

journal_title

Human immunology

authors

Eckels DD,Woody JN,Hartzman RJ

doi

10.1016/0198-8859(81)90050-1

subject

Has Abstract

pub_date

1981-10-01 00:00:00

pages

133-42

issue

2

eissn

0198-8859

issn

1879-1166

pii

0198-8859(81)90050-1

journal_volume

3

pub_type

杂志文章

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