Abstract：
:To investigate the prevalence of obsessive-compulsive disorder (OCD) and obsessive-compulsive symptoms (OCS) and their association with demographic and clinical factors, 92 inpatients with chronic schizophrenia participated in this study. Demographic factors, severity of psychiatric symptoms as determined by Brief Psychiatric Rating Scale and OCS by Yale-Brown Obsessive Compulsive Scale, general functioning, extrapyramidal symptoms, and dose of antipsychotics were compared between patients with and without OCD or OCS. The Mini-International Neuropsychiatric Interview was employed for diagnosis of OCD and OCS. OCD and OCS were observed in 14.1% and 51.1% of inpatients with schizophrenia, respectively. Schizophrenic patients with OCS exhibited significantly earlier onset of schizophrenia, lower socioeconomic status, and more severe psychiatric symptoms than those without OCS. Earlier hospitalization of schizophrenia, family history of psychosis, and more severe schizophrenic symptoms were associated with comorbidity of OCS, as determined by logistic regression analysis, and younger age was associated with more severe OCS. However, negative symptoms were associated with comorbidity of OCD in chronic schizophrenia. Our findings suggest there is a subtype of schizophrenia with OCS, which is related to earlier onset and more severe psychotic symptoms.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Owashi T,Ota A,Otsubo T,Susa Y,Kamijima Kdoi
10.1016/j.psychres.2009.08.003subject
Has Abstractpub_date
2010-10-30 00:00:00pages
241-6issue
3eissn
0165-1781issn
1872-7123pii
S0165-1781(09)00293-5journal_volume
179pub_type
杂志文章abstract：:Chronic imipramine administration decreases the density of serotonin S2 and beta-adrenergic receptors. The mode of action is not clear but might be assumed to be a result of imipramine interacting with its high affinity binding sites on presynaptic serotonin neurons. To investigate this possibility and the role of the...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(83)90045-8
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abstract：:Although social skills training (SST) is an effective approach for improving social skills for schizophrenia, the motivational deficit attenuates its efficacy. Virtual reality (VR) applications have allowed individuals with mental disabilities to enhance their motivation for rehabilitation. We compared SST using VR ro...
journal_title：Psychiatry research
pub_type： 杂志文章,随机对照试验
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更新日期：2011-09-30 00:00:00
abstract：:Studies investigating self-esteem in individuals with severe mental illness, either as a treatment goal, outcome or correlate to other variables, have increased over the past few years. One of the main difficulties in assessing self-esteem is the assessment itself, often measuring global and stable self-esteem as in t...
journal_title：Psychiatry research
pub_type： 杂志文章
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2011.11.018
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pub_type： 杂志文章
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journal_title：Psychiatry research
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pub_type： 临床试验,杂志文章
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pub_type： 杂志文章
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journal_title：Psychiatry research
pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：Psychiatry research
pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：Psychiatry research
pub_type： 杂志文章,meta分析
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pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：Psychiatry research
pub_type： 杂志文章
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