Abstract：
:Glycoconjugate vaccines have been proven safe and effective against various diseases in children. Although these vaccines have a history of effectiveness, there are still many unanswered questions to be addressed, including conjugate interference when multiple vaccines are administered at one time, expansion of serotype coverage, effectiveness in special populations, and issues relating to conjugate vaccine use in the developing world. This paper focuses on the use of CRM(197) as a carrier protein, contrasting it to other carrier proteins used in single-antigen pediatric vaccines as well as identifying areas for future study.
journal_name
Vaccinejournal_title
Vaccineauthors
Shinefield HRdoi
10.1016/j.vaccine.2010.04.072subject
Has Abstractpub_date
2010-06-17 00:00:00pages
4335-9issue
27eissn
0264-410Xissn
1873-2518pii
S0264-410X(10)00608-0journal_volume
28pub_type
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