Human fetal liver-derived stem cell transplantation as supportive modality in the management of end-stage decompensated liver cirrhosis.

abstract：:Periosteal autografts have the potential to regenerate articular cartilage defects, but this potential is limited by the patient's age. Allograft transplantation from a young donor to an older recipient might bypass this limitation. The effect of the time delay, between death and harvesting of a periosteal graft, on t...

journal_title：Cell transplantation

authors： O'Driscoll SW,Meisami B,Miura Y,Fitzsimmons JS

更新日期：1999-11-01 00:00:00

abstract：:The ability to replace damaged myocardial tissue with new striated muscle would constitute a major advance in the treatment of diseases that irreversibly injure cardiac muscle cells. The creation of focal grafts of skeletal muscle has been reported following the intramural injection of skeletal myoblasts into both nor...

journal_title：Cell transplantation

authors： Robinson SW,Cho PW,Levitsky HI,Olson JL,Hruban RH,Acker MA,Kessler PD

更新日期：1996-01-01 00:00:00

abstract：:The human neuronal cell-1 (HCN-1) line has recently been established. Under favorable conditions, these cells differentiate into mature neuronal phenotypes. Here we report on further characterization of these cells. Cultured HCN-1 cells express fibronectin immunoreactivity and grow well on fibronectin substrate but do...

journal_title：Cell transplantation

authors： Poltorak M,Isono M,Freed WJ,Ronnett GV,Snyder SH

更新日期：1992-01-01 00:00:00

abstract：:The present study was designed to evaluate the use of collagen gel loaded with human retinal pigment epithelium (ARPE19) in cellular transfer and to assess its viability within the gel. Collagen solution was prepared by dissolving calfskin in hydrochloric acid to make a final concentration of 2.0 mg/ml and this was mi...

journal_title：Cell transplantation

authors： Yeung CK,Chiang SW,Chan KP,Lam DS,Pang CP

更新日期：2004-01-01 00:00:00

abstract：:Cell therapy has been shown to be a promising alternative therapy for neurorestoration, and more than 30 different types of cells have been shown to possess some capability to restore lost or damaged neurological functions. Chinese physicians have successfully applied cell therapy to many neurological diseases and dam...

journal_title：Cell transplantation

authors： Chinese Branch of International Association of Neurorestoratology (IANR).,Preparatory Committee of Chinese Association of Neurorestoratology.

更新日期：2013-01-01 00:00:00

abstract：:There is still a lack of sufficient research on the mechanism behind neurogenic bladder (NB) treatment. The aim of this study was to explore the effect of overexpressed stromal cell-derived factor-1 (SDF-1) secreted by engineered immortalized mesenchymal stem cells (imMSCs) on the NB. In this study, primary bone marro...

journal_title：Cell transplantation

authors： Zhu GQ,Jeon SH,Lee KW,Cho HJ,Ha US,Hong SH,Lee JY,Kwon EB,Kim HJ,Lee SM,Kim HY,Kim SW,Bae WJ

更新日期：2020-01-01 00:00:00

abstract：:In this study, we assessed the ability of miR-26b-5p to regulate T cell factor 4 (TCF-4) expression and thereby control human adipose-derived mesenchymal stem cell (hADMSC) adipogenic differentiation. Adipogenic medium was used to induce hADMSC differentiation over a 6-d period. The ability of miR-26b-5p to interact w...

journal_title：Cell transplantation

authors： Luo Y,Ji H,Cao Y,Ding X,Li M,Song H,Li S,WaTableng C,Wu H,Meng J,Du H

更新日期：2020-01-01 00:00:00

abstract：:Human islets are subjected to a number of stresses before and during their isolation that may influence their survival and engraftment after transplantation. Apoptosis is likely to be activated in response to these stresses. Apoptosis due to intrinsic stresses is regulated by pro- and antiapoptotic members of the Bcl...

journal_title：Cell transplantation

authors： Campbell PD,Weinberg A,Chee J,Mariana L,Ayala R,Hawthorne WJ,O'Connell PJ,Loudovaris T,Cowley MJ,Kay TW,Grey ST,Thomas HE

更新日期：2012-01-01 00:00:00

abstract：:Multiple sclerosis is a disease characterized by inflammation and demyelination located in the central nervous system. Experimental autoimmune encephalomyelitis (EAE) is the most common animal model for multiple sclerosis (MS). Although the roles of T cells in MS/EAE have been well investigated, little is known about ...

journal_title：Cell transplantation

authors： Xu J,Wang Y,Jiang H,Sun M,Gao J,Xie A

更新日期：2019-09-01 00:00:00

abstract：:An important challenge in pancreatic islet transplantation in association with type 1 diabetes is to define automatic high-throughput assays for evaluation of human islet function. The physiological techniques presently used are amenable to small-scale experimental samples and produce descriptive results. The postgeno...

journal_title：Cell transplantation

authors： Cabrera O,Jacques-Silva MC,Berman DM,Fachado A,Echeverri F,Poo R,Khan A,Kenyon NS,Ricordi C,Berggren PO,Caicedo A

更新日期：2008-01-01 00:00:00

abstract：:Our purpose was to evaluate whether or not and when phenotypic modulation of smooth muscle cells (SMCs) in hybrid vascular prostheses preincorporated with SMCs occurs upon implantation. Two types of hybrid vascular grafts incorporated with vascular cells derived from canine jugular veins were prepared: grafts containi...

journal_title：Cell transplantation

authors： Kanda K,Miwa H,Matsuda T

更新日期：1995-11-01 00:00:00

abstract：:Posttransplant infusion of viable donor bone marrow cells (DBMC) has been shown in our previous studies to promote acceptance of incompatible kidney allografts in rhesus monkeys after treatment with polyclonal antithymocyte globulin to deplete peripheral T-lymphocytes. In this nonhuman primate model, the infusion of t...

journal_title：Cell transplantation

authors： Smith JP,Kasten-Jolly J,Rebellato L,Haisch CE,Thomas JM

更新日期：1997-07-01 00:00:00

abstract：:Autism spectrum disorders (ASDs) are heterogeneous complex neurodevelopmental pathologies defined by behavioral symptoms, but which have well-characterized genetic, immunological, and physiological comorbidities. Despite extensive research efforts, there are presently no agreed upon therapeutic approaches for either t...

journal_title：Cell transplantation

authors： Bradstreet JJ,Sych N,Antonucci N,Klunnik M,Ivankova O,Matyashchuk I,Demchuk M,Siniscalco D

更新日期：2014-01-01 00:00:00

abstract：:We attempted to regenerate bone in a significant osseous defect with various stem cells from deciduous teeth, extracted from puppies, and grafted them into a parent canine mandible as an allograft, parent dental pulp, and bone marrow by tissue engineering and regenerative medicine technology using platelet-rich plasm...

journal_title：Cell transplantation

authors： Yamada Y,Ito K,Nakamura S,Ueda M,Nagasaka T

更新日期：2011-01-01 00:00:00

abstract：:Pigs share many anatomical and physiological features with humans, offering a unique and viable model for biomedical research. Although porcine female germline stem cells (FGSCs) were identified in the juvenile ovary, no reports described the isolation and purification of FGSCs from the pig at sexual maturity. Here, w...

journal_title：Cell transplantation

authors： Hou L,Wang J,Li X,Wang H,Liu G,Xu B,Mei X,Hua X,Wu J

更新日期：2018-08-01 00:00:00

abstract：:Efficient maintenance of the undifferentiated status of embryonic stem cells (ESCs) may be important for preparation of high-quality cell sources that can be successfully used for stem cell research and therapy. Here we tried to identify a compound that can enhance the quality of pluripotent stem cells. Treatment of E...

journal_title：Cell transplantation

authors： Han D,Kim HJ,Choi HY,Kim B,Yang G,Han J,Dayem AA,Lee HR,Kim JH,Lee KM,Jeong KS,Do SH,Cho SG

更新日期：2015-01-01 00:00:00

abstract：:Efficient repopulation by transplanted hepatocytes in the severely injured liver is essential for their clinical application in the treatment of acute hepatic failure. We studied here whether and how the transplanted hepatocytes are able to efficiently repopulate the toxin-induced acute injured liver. Male dipeptidyl ...

journal_title：Cell transplantation

authors： Yu CH,Chen HL,Chen YH,Chang MF,Chien CS,Chang MH

更新日期：2009-01-01 00:00:00

abstract：:Critical length nerve defects in the rat sciatic nerve model were reconstructed with chitosan nerve guides filled with Schwann cells (SCs) containing hydrogel. The transplanted SCs were naive or had been genetically modified to overexpress neurotrophic factors, thus providing a cellular neurotrophic factor delivery sy...

journal_title：Cell transplantation

authors： Meyer C,Wrobel S,Raimondo S,Rochkind S,Heimann C,Shahar A,Ziv-Polat O,Geuna S,Grothe C,Haastert-Talini K

更新日期：2016-01-01 00:00:00

abstract：:Experiments are described using rats with two kinds of brain damage and consequent cognitive deficit (in the Morris water maze, three-door runway, and radial maze): 1) ischemic damage to the CA1 hippocampal cell field after four-vessel occlusion (4VO), and 2) damage to the forebrain cholinergic projection system by lo...

journal_title：Cell transplantation

authors： Gray JA,Grigoryan G,Virley D,Patel S,Sinden JD,Hodges H

更新日期：2000-03-01 00:00:00

abstract：:Potential labels for identifying embryonic raphe neurons and a clonal, neuronally differentiating, raphe-derived cell line, RN33B, in CNS transplantation studies were tested by first characterizing the labels in vitro. The labels that were tested included 4',6-diamidino-2-phenylindole hydrochloride, 1,1'-dioctadecyl-3...

journal_title：Cell transplantation

authors： Onifer SM,White LA,Whittemore SR,Holets VR

更新日期：1993-03-01 00:00:00

abstract：:Neuroblastoma, a malignant tumor of the sympathetic nervous system, is an aggressive extracranial tumor in childhood. Long noncoding RNAs (lncRNAs) have been discovered to play a key role in the eukaryotic regulatory gene network and be involved in a wide variety of biological processes. We observed that the expressio...

journal_title：Cell transplantation

authors： Pan W,Wu A,Yu H,Yu Q,Zheng B,Yang W,Tian D,Gao Y,Li P

更新日期：2020-01-01 00:00:00

abstract：:Critical limb ischemia in diabetic patients is associated with high rates of morbidity and mortality. Suboptimal responses to the available medical and surgical treatments are common in these patients, who also demonstrate limited vascular homeostasis. Neovasculogenesis induced by stem cell therapy could be a useful ...

journal_title：Cell transplantation

authors： Ruiz-Salmeron R,de la Cuesta-Diaz A,Constantino-Bermejo M,Pérez-Camacho I,Marcos-Sánchez F,Hmadcha A,Soria B

更新日期：2011-01-01 00:00:00

abstract：:The immunomodulatory characteristics of mesenchymal stromal cells (MSCs) may lead to multifaceted strategies in rejection of organ transplantation. This study was designed to investigate, first, the effect of the donor-type MSCs from Wistar rats on the immune system of immunocompetent Lewis rats and, second, the rejec...

journal_title：Cell transplantation

authors： Merino A,Ripoll E,de Ramon L,Bolaños N,Goma M,Bestard O,Lloberas N,Grinyo JM,Ambròs JT

更新日期：2017-06-09 00:00:00

abstract：:Despite the high prevalence and devastating outcome, there remain a few options for treatment of ischemic stroke. Currently available treatments are limited by a short time window for treatment and marginal efficacy when used. We have tested a human umbilical cord blood-derived stem cell line that has been shown to re...

journal_title：Cell transplantation

authors： Hocum Stone LL,Xiao F,Rotschafer J,Nan Z,Juliano M,Sanberg CD,Sanberg PR,Kuzmin-Nichols N,Grande A,Cheeran MC,Low WC

更新日期：2016-01-01 00:00:00

abstract：:Bone marrow (BM) cells may interact with coronary endothelium and modulate coronary atherosclerosis. We investigated the time course of coronary luminal loss and changes in conductance after intracoronary injection of enriched hematopoietic BM stem cells in patients with previous myocardial infarction (MI). Among 24 p...

journal_title：Cell transplantation

authors： Vanderheyden M,Vercauteren S,Mansour S,Delrue L,Vandekerckhove B,Heyndrickx GR,Van Haute I,De Bruyne B,Timmermans F,Wijns W,Bartunek J

更新日期：2007-01-01 00:00:00

abstract：:A human embryonic stem cell (HESC) line, H1, was studied after differentiation to a dopaminergic phenotype in vitro in order to carry out in vivo studies in Parkinsonian monkeys. To identify morphological characteristics of transplanted donor cells, HESCs were transfected with a GFP lentiviral vector. Gene expression ...

journal_title：Cell transplantation

authors： Wakeman DR,Weiss S,Sladek JR,Elsworth JD,Bauereis B,Leranth C,Hurley PJ,Roth RH,Redmond DE

更新日期：2014-01-01 00:00:00

abstract：:For clinical islet transplantation, isolated islets deteriorate rapidly in culture, although culturing islets prior to transplantation provides flexibility for evaluation of isolated islets and pretreatment of patients. In the present study, we compared human fresh islets to cultured islets with in vitro and in vivo ...

journal_title：Cell transplantation

authors： Noguchi H,Naziruddin B,Jackson A,Shimoda M,Ikemoto T,Fujita Y,Chujo D,Takita M,Peng H,Sugimoto K,Itoh T,Kobayashi N,Onaca N,Levy MF,Matsumoto S

更新日期：2012-01-01 00:00:00

abstract：:Huntington's disease (HD) is a devastating neurodegenerative disorder that occurs in patients with a mutation in the huntingtin or IT15 gene. Patients are plagued by early cognitive signs, motor deficits, and psychiatric disturbances. Symptoms are attributed to cell death in the striatum and disruption of cortical-str...

journal_title：Cell transplantation

authors： Ramaswamy S,Shannon KM,Kordower JH

更新日期：2007-01-01 00:00:00

abstract：:In diabetic patients cardiovascular morbidity and mortality is still a major problem. Our aim was to study the effect of kidney-pancreas transplantation on survival, cardiovascular events, and causes of death in diabetic type 1 uremic patients. Three hundred and thirty-three uremic IDDM patients were enrolled in our w...

journal_title：Cell transplantation

authors： La Rocca E,Fiorina P,Astorri E,Rossetti C,Lucignani G,Fazio F,Giudici D,Castoldi R,Bianchi G,Di Carlo V,Pozza G,Secchi A

更新日期：2000-11-01 00:00:00

abstract：:ZNF281 is one of the core transcription factors in embryonic stem cells (ESCs) and has activation and repression roles in the transcription of ESC genes. A known target molecule of Zfp281 (the mouse homologue of ZNF281) is Nanog. However, NANOG is not expressed in most human multipotent stem cells (hMSCs). Here, we in...

journal_title：Cell transplantation

authors： Seo KW,Roh KH,Bhandari DR,Park SB,Lee SK,Kang KS

更新日期：2013-01-01 00:00:00