Peripheral Nerve Regeneration Through Hydrogel-Enriched Chitosan Conduits Containing Engineered Schwann Cells for Drug Delivery.

abstract：:The long-term durability of agarose microencapsulated islets against autoimmunity was evaluated in NOD mice. Islets were isolated from 6-8-week-old prediabetic male NOD mice and microencapsulated in 5% agarose hydrogel. Microencapsulated or nonencapsulated islets were transplanted into the omental pouch of spontaneous...

journal_title：Cell transplantation

authors： Kobayashi T,Aomatsu Y,Iwata H,Kin T,Kanehiro H,Hisanga M,Ko S,Nagao M,Harb G,Nakajima Y

更新日期：2006-01-01 00:00:00

abstract：:The technologies for adipose tissue harvesting, processing, and transplantation have substantially evolved in the past two decades. Clinically driven advancements have paralleled a significant improvement in the understanding of cellular, molecular, and immunobiological events surrounding cell and tissue transplantati...

journal_title：Cell transplantation

authors： Tremolada C,Palmieri G,Ricordi C

更新日期：2010-01-01 00:00:00

abstract：:Electrostimulation represents a well-known trophic factor for different tissues. In vitro electrostimulation of non-stem and stem cells induces myogenic predifferentiation and may be a powerful tool to generate cells with the capacity to respond to local areas of injury. We evaluated the effects of in vivo electrostim...

journal_title：Cell transplantation

authors： Spadaccio C,Rainer A,De Marco F,Lusini M,Gallo P,Sedati P,Muda AO,De Porcellinis S,Gregorj C,Avvisati G,Trombetta M,Chello M,Covino E,Bull DA,Patel AN,Genovese JA

更新日期：2013-01-01 00:00:00

abstract：:Protocols of donor bone marrow infusion for tolerance induction are receiving increasing attention in clinical trials of organ allotransplantation. We report pulmonary embolism with bone fragments following vertebral body marrow infusion in a recipient of a liver and intestinal transplant. Even though pulmonary emboli...

journal_title：Cell transplantation

authors： Fernandez LA,Romaguera R,Viciana AL,Ruiz P,Tzakis AG,Ricordi C

更新日期：1996-07-01 00:00:00

abstract：:Cotransplantation of neural progenitors (NPs) with Schwann cells (SCs) might be a way to overcome low rate of neuronal differentiation of NPs following transplantation in spinal cord injury (SCI) and the improvement of locomotor recovery. In this study, we initially generated NPs from human embryonic stem cells (hESC...

journal_title：Cell transplantation

authors： Niapour A,Karamali F,Nemati S,Taghipour Z,Mardani M,Nasr-Esfahani MH,Baharvand H

更新日期：2012-01-01 00:00:00

abstract：:Huntington's disease (HD) is a devastating neurodegenerative disorder that occurs in patients with a mutation in the huntingtin or IT15 gene. Patients are plagued by early cognitive signs, motor deficits, and psychiatric disturbances. Symptoms are attributed to cell death in the striatum and disruption of cortical-str...

journal_title：Cell transplantation

authors： Ramaswamy S,Shannon KM,Kordower JH

更新日期：2007-01-01 00:00:00

abstract：:The formation of a new microvasculature is essential for the long-term survival and function of the islet graft. In this study we examined endothelium of isolated pancreatic islets by stimulation with growth factors, different culture conditions, and genetic modification. We also inspected the effect of immunosuppress...

journal_title：Cell transplantation

authors： Kidszun A,Schneider D,Erb D,Hertl G,Schmidt V,Eckhard M,Preissner KT,Breier G,Bretzel RG,Linn T

更新日期：2006-01-01 00:00:00

abstract：:This study is a preliminary investigation to determine if bone marrow-derived cells, when implanted into freeze-injured urinary bladders, differentiate into smooth muscle cells and reconstruct smooth muscle layers. Bone marrow cells were harvested from femurs of male ICR mice and cultured in collagen-coated dishes for...

journal_title：Cell transplantation

authors： Imamura T,Kinebuchi Y,Ishizuka O,Seki S,Igawa Y,Nishizawa O

更新日期：2008-01-01 00:00:00

abstract：:Ischemia-reperfusion and immunosuppressive therapy are a major cause of progressive renal failure after kidney transplantation. Recent studies have shown that administration of bone marrow mesenchymal stem cells (MSCs) improves kidney functional recovery in the acute phase of post ischemia-reperfusion injury. In the ...

journal_title：Cell transplantation

authors： Alfarano C,Roubeix C,Chaaya R,Ceccaldi C,Calise D,Mias C,Cussac D,Bascands JL,Parini A

更新日期：2012-01-01 00:00:00

abstract：:Investigations indicate that an extract of green tea, polyphenol, can significantly increase the culture survival rate of rat islets without deteriorating their functionality. In this study, we examined the effect of adding polyphenol to islets isolated from human pancreata and nonhuman primate pancreata. Islets were ...

journal_title：Cell transplantation

authors： Zhang G,Matsumoto S,Hyon SH,Qualley SA,Upshaw L,Strong DM,Reems JA

更新日期：2004-01-01 00:00:00

abstract：:To learn more about nonimmune-mediated islet graft failure, we transplanted different preparations (preps) of isolated human islets under the kidney capsule of streptozotocin (STZ)-diabetic nude mice. One month after the implantation of 1,000 or 2,000 islets, grafts were harvested for morphological, immunohistochemica...

journal_title：Cell transplantation

authors： Davalli AM,Perego L,Bertuzzi F,Finzi G,La Rosa S,Blau A,Placidi C,Nano R,Gregorini L,Perego C,Capella C,Folli F

更新日期：2008-01-01 00:00:00

abstract：:Human islets are subjected to a number of stresses before and during their isolation that may influence their survival and engraftment after transplantation. Apoptosis is likely to be activated in response to these stresses. Apoptosis due to intrinsic stresses is regulated by pro- and antiapoptotic members of the Bcl...

journal_title：Cell transplantation

authors： Campbell PD,Weinberg A,Chee J,Mariana L,Ayala R,Hawthorne WJ,O'Connell PJ,Loudovaris T,Cowley MJ,Kay TW,Grey ST,Thomas HE

更新日期：2012-01-01 00:00:00

abstract：:Neuronal progenitor cells (NPCs) derived from human embryonic stem cells (hESCs) are an excellent cell source for transplantation therapy due to their availability and ethical acceptability. However, the traditional method of expansion and differentiation of hESCs into NPCs in monolayer cultures requires a long time, ...

journal_title：Cell transplantation

authors： Qiu L,Lim YM,Chen AK,Reuveny S,Oh SK,Tan EK,Zeng L

更新日期：2016-01-01 00:00:00

abstract：:The need for chronic immune suppression (IS) is one of the hurdles precluding widespread use of islet cell transplantation to restore glycemic control in patients with type 1 diabetes. We report the case of a healthy nonhuman primate (NHP) treated on and off for over 2.5 years with steroid-free IS, consisting of dacli...

journal_title：Cell transplantation

authors： Berman DM,Ruiz P Jr,Blandino-Rosano M,Bernal-Mizrachi E,Kenyon NS

更新日期：2019-03-01 00:00:00

abstract：:Natural immunological tolerance can be induced in certain types of allogeneic liver transplantation in rats. To screen for genes associated with the induction of tolerance, suppression subtractive hybridization was performed in the rat liver transplantation model between a DA donor and PVG recipient combination where ...

journal_title：Cell transplantation

authors： Zhang H,Ohmi K,Hirasawa A,Enosawa S,Hara Y,Tamura A,Tsujimoto G

更新日期：2008-01-01 00:00:00

abstract：:Sciatic nerve injuries, not uncommon in trauma with a limited degree of functional recovery, are considered a persistent clinical, social, and economic problem worldwide. Accumulating evidence suggests that stem cells can promote the tissue regeneration through various mechanisms. The aim of the present study was to i...

journal_title：Cell transplantation

authors： Chuang MH,Ho LH,Kuo TF,Sheu SY,Liu YH,Lin PC,Tsai YC,Yang CH,Chu CM,Lin SZ

更新日期：2020-01-01 00:00:00

abstract：:Membrane integrity fluorescent staining is used routinely to evaluate islet viability. Results are used as one of the determining factors in islet product release criteria, and are used to assess the efficacy of different culture conditions. Recently, it has been observed that there is variation in the viability stain...

journal_title：Cell transplantation

authors： Barnett MJ,McGhee-Wilson D,Shapiro AM,Lakey JR

更新日期：2004-01-01 00:00:00

abstract：:Potential labels for identifying embryonic raphe neurons and a clonal, neuronally differentiating, raphe-derived cell line, RN33B, in CNS transplantation studies were tested by first characterizing the labels in vitro. The labels that were tested included 4',6-diamidino-2-phenylindole hydrochloride, 1,1'-dioctadecyl-3...

journal_title：Cell transplantation

authors： Onifer SM,White LA,Whittemore SR,Holets VR

更新日期：1993-03-01 00:00:00

abstract：:The common use of the marrow autograft mononuclear cell (MNC) count derives from positive correlative studies following allogeneic transplantation and from earlier conflicting data regarding the value of the bone marrow autograft colony-forming unit granulocyte-macrophage (CFU-GM) assay for prediction hematologic reco...

journal_title：Cell transplantation

authors： al-Fiar F,Prince HM,Imrie K,Stewart AK,Crump M,Keating A

更新日期：1997-09-01 00:00:00

abstract：:Alzheimer disease (AD) is a progressive neurodegenerative disease, which is characterized by loss of memory and cognitive function. In AD patients dysfunction of the cholinergic system is the main cause of cognitive disorders, and decreased activity of choline acetyltransferase (ChAT), an enzyme responsible for acety...

journal_title：Cell transplantation

authors： Park D,Joo SS,Kim TK,Lee SH,Kang H,Lee HJ,Lim I,Matsuo A,Tooyama I,Kim YB,Kim SU

更新日期：2012-01-01 00:00:00

abstract：:Grafting autologous cultured satellite cells in irreversibly injured rat extensor digitorum longus EDL muscle leads to myofiber regeneration at the grafting site. In this study, we investigated whether cell grafts induced functional improvement and correlated mechanophysiological findings with histological observation...

journal_title：Cell transplantation

authors： Alameddine HS,Louboutin JP,Dehaupas M,Sébille A,Fardeau M

更新日期：1994-01-01 00:00:00

abstract：:Stem cell transplants into damaged myocardium may have the potential to improve cardiac function. We investigated the safety of transplanting unmanipulated autologous bone marrow into infarcted myocardium of patients undergoing coronary bypass surgery and assessed its efficacy to improve cardiac function. Fourteen pat...

journal_title：Cell transplantation

authors： Galiñanes M,Loubani M,Davies J,Chin D,Pasi J,Bell PR

更新日期：2004-01-01 00:00:00

abstract：:Mouse embryonal carcinoma cell line P19 could be differentiated to neurons or glial cells by appropriate induction. We introduced the lacZ gene driven by a calmodulin promoter into P19 cells, and cloned the transfectant CaM-Z that showed the strong expression of lacZ gene after the induction of differentiation. CaM-Z ...

journal_title：Cell transplantation

authors： Watanabe R,Takase-Yoden S,Ikeda T,Atsumi T

更新日期：1996-09-01 00:00:00

abstract：:Alzheimer's disease (AD) is a type of neurodegenerative disorder and the most common form of dementia. MicroRNA (miRNA) has been shown to play a role in various diseases, including AD. It also has been reported to regulate autophagy. We extracted miRNA from blood samples and constructed an miRNA-101a lentivirus vector...

journal_title：Cell transplantation

authors： Li Q,Wang Y,Peng W,Jia Y,Tang J,Li W,Zhang JH,Yang J

更新日期：2019-08-01 00:00:00

abstract：:Successful transplantation of cadaver embryonic neural tissue is highly dependent on the method used to obtain the tissue. It is important that the tissue not be contaminated bacteriologically by vaginal flora during the procedure, and that it not be disrupted mechanically. A low-pressure aspiration abortion technique...

journal_title：Cell transplantation

authors： Nauert GM,Freeman TB

更新日期：1994-03-01 00:00:00

abstract：:Adrenal medullary tissue including chromaffin cells was grafted intrathecally in cancer patients to relieve intractable pain. The central nervous system (CNS) is considered an immune privileged site. Therefore, non-HLA-matched and unencapsulated tissue was grafted in 15 patients and 1 sham control in a series of at le...

journal_title：Cell transplantation

authors： Tkaczuk J,Bes JC,Duplan H,Sallerin B,Tafani M,Charlet JP,Abbal M,Lazorthes Y,Ohayon E

更新日期：2000-01-01 00:00:00

abstract：:Critical limb ischemia in diabetic patients is associated with high rates of morbidity and mortality. Suboptimal responses to the available medical and surgical treatments are common in these patients, who also demonstrate limited vascular homeostasis. Neovasculogenesis induced by stem cell therapy could be a useful ...

journal_title：Cell transplantation

authors： Ruiz-Salmeron R,de la Cuesta-Diaz A,Constantino-Bermejo M,Pérez-Camacho I,Marcos-Sánchez F,Hmadcha A,Soria B

更新日期：2011-01-01 00:00:00

abstract：:Cell therapy has attracted considerable interest as a promising therapeutic alternative for patients with Parkinson's disease (PD). Clinical studies have shown that grafted fetal neural tissue can achieve considerable biochemical and clinical improvements in PD. However, the source of fetal tissue grafts is limited an...

journal_title：Cell transplantation

authors： Gonzalez R,Garitaonandia I,Poustovoitov M,Abramihina T,McEntire C,Culp B,Attwood J,Noskov A,Christiansen-Weber T,Khater M,Mora-Castilla S,To C,Crain A,Sherman G,Semechkin A,Laurent LC,Elsworth JD,Sladek J,Snyder EY,

更新日期：2016-11-01 00:00:00

abstract：:Spinal cord injury (SCI) causes loss of neural functions below the level of the lesion due to interruption of spinal pathways and secondary neurodegenerative processes. The transplant of neural stem cells (NSCs) is a promising approach for the repair of SCI. Reprogramming of adult somatic cells into induced pluripoten...

journal_title：Cell transplantation

authors： López-Serrano C,Torres-Espín A,Hernández J,Alvarez-Palomo AB,Requena J,Gasull X,Edel MJ,Navarro X

更新日期：2016-10-01 00:00:00

abstract：:ZNF281 is one of the core transcription factors in embryonic stem cells (ESCs) and has activation and repression roles in the transcription of ESC genes. A known target molecule of Zfp281 (the mouse homologue of ZNF281) is Nanog. However, NANOG is not expressed in most human multipotent stem cells (hMSCs). Here, we in...

journal_title：Cell transplantation

authors： Seo KW,Roh KH,Bhandari DR,Park SB,Lee SK,Kang KS

更新日期：2013-01-01 00:00:00