Phenotypic reversion of smooth muscle cells in hybrid vascular prostheses.

abstract：:Simple and efficient freezing methods with maximal postthawing recovery form the basis of ideal cryopreservation. Taurine (2-amino ethanesulfonic acid), an end-product of sulphur amino acid metabolism, is one of the most abundant free amino acids in the body. The membrane stabilizing, free radical scavenging, and osmo...

journal_title：Cell transplantation

authors： Hardikar AA,Risbud MV,Remacle C,Reusens B,Hoet JJ,Bhonde RR

更新日期：2001-01-01 00:00:00

abstract：:The aim of this work was to determine the effect of nicotine desensitization on dopamine (DA) release in the dorsal striatum and shell of the nucleus accumbens (NAc) from brain slices. In vitro fast-scan cyclic voltammetry analysis was used to evaluate dopamine release in the dorsal striatum and the NAc shell of Sprag...

journal_title：Cell transplantation

authors： Chen YH,Lin BJ,Hsieh TH,Kuo TT,Miller J,Chou YC,Huang EY,Hoffer BJ

更新日期：2019-03-01 00:00:00

abstract：:Critical limb ischemia in diabetic patients is associated with high rates of morbidity and mortality. Suboptimal responses to the available medical and surgical treatments are common in these patients, who also demonstrate limited vascular homeostasis. Neovasculogenesis induced by stem cell therapy could be a useful ...

journal_title：Cell transplantation

authors： Ruiz-Salmeron R,de la Cuesta-Diaz A,Constantino-Bermejo M,Pérez-Camacho I,Marcos-Sánchez F,Hmadcha A,Soria B

更新日期：2011-01-01 00:00:00

abstract：:An in vivo tracer technique that uses radiolabeled insulin as the tracer molecule has been developed to assess the rate of chemical transport between the cell transplantation chamber of an implantable bioartificial device and the host's circulatory system. The device considered here employs site-directed neovasculariz...

journal_title：Cell transplantation

authors： Sarver JG,Fournier RL,Goldblatt PJ,Phares TL,Mertz SE,Baker AR,Mellon RJ,Horner JM,Selman SH

更新日期：1995-03-01 00:00:00

abstract：REGISTRATION NUMBER OF CLINICAL TRIALS:ChiCTR1900021317. ...

journal_title：Cell transplantation

authors： He M,Guo X,Li T,Jiang X,Chen Y,Yuan Y,Chen B,Yang G,Fan Y,Liang Z,Armstrong DG,Deng W

更新日期：2020-01-01 00:00:00

abstract：:The technologies for adipose tissue harvesting, processing, and transplantation have substantially evolved in the past two decades. Clinically driven advancements have paralleled a significant improvement in the understanding of cellular, molecular, and immunobiological events surrounding cell and tissue transplantati...

journal_title：Cell transplantation

authors： Tremolada C,Palmieri G,Ricordi C

更新日期：2010-01-01 00:00:00

abstract：:Cellular transplantation strategies utilizing intraspinal or intrathecal olfactory ensheathing cells (OECs) have been reported as beneficial for spinal cord injury (SCI). However, there are many disadvantages of these methods, including additional trauma to the spinal cord parenchyma and technical challenges. Therefor...

journal_title：Cell transplantation

authors： Zhang L,Zhuang X,Chen Y,Xia H

更新日期：2019-12-01 00:00:00

abstract：:Pigs share many anatomical and physiological features with humans, offering a unique and viable model for biomedical research. Although porcine female germline stem cells (FGSCs) were identified in the juvenile ovary, no reports described the isolation and purification of FGSCs from the pig at sexual maturity. Here, w...

journal_title：Cell transplantation

authors： Hou L,Wang J,Li X,Wang H,Liu G,Xu B,Mei X,Hua X,Wu J

更新日期：2018-08-01 00:00:00

abstract：:The clinical consequences of acute liver failure are associated with high mortality. Intensive medical intervention is required to treat the symptoms of liver failure, including coagulopathy, metabolic instability, and encephalopathy. Providing temporary liver support with an extracorporeal liver assist device could s...

journal_title：Cell transplantation

authors： Gregory PG,Connolly CK,Toner M,Sullivan SJ

更新日期：2000-01-01 00:00:00

abstract：:Osteoarthritis (OA) is degenerative disease, leading to pain and functional disability. It is reported that polydeoxyribonucleotide (PDRN) is a suitable therapy for OA. However, the therapeutic mechanisms of PDRN in OA are not fully understood. To investigate the effect of PDRN in an in vitro model of OA, interleukin ...

journal_title：Cell transplantation

authors： Baek A,Kim Y,Lee JW,Lee SC,Cho SR

更新日期：2018-11-01 00:00:00

abstract：:Autologous cardiosphere-derived cells (CDCs) were the first therapeutic modality to demonstrate myocardial regeneration with a decrease in scar size and an increase in viable, functional tissue. Widespread applicability of autologous CDC therapy is limited by the need for patient-specific myocardial biopsy, cell proce...

journal_title：Cell transplantation

authors： Chakravarty T,Makkar RR,Ascheim DD,Traverse JH,Schatz R,DeMaria A,Francis GS,Povsic TJ,Smith RR,Lima JA,Pogoda JM,Marbán L,Henry TD

更新日期：2017-02-16 00:00:00

abstract：:Despite the substantial efforts to elucidate the role of early brain injury in subarachnoid hemorrhage (SAH), an effective pharmaceutical therapy for patients with SAH continues to be unavailable. This study aims to reveal the role of necroptosis after SAH, and explore whether the disruption of the blood-brain barrier...

journal_title：Cell transplantation

authors： Chen J,Jin H,Xu H,Peng Y,Jie L,Xu D,Chen L,Li T,Fan L,He P,Ying G,Gu C,Wang C,Wang L,Chen G

更新日期：2019-11-01 00:00:00

abstract：:Adrenal medullary tissue including chromaffin cells was grafted intrathecally in cancer patients to relieve intractable pain. The central nervous system (CNS) is considered an immune privileged site. Therefore, non-HLA-matched and unencapsulated tissue was grafted in 15 patients and 1 sham control in a series of at le...

journal_title：Cell transplantation

authors： Tkaczuk J,Bes JC,Duplan H,Sallerin B,Tafani M,Charlet JP,Abbal M,Lazorthes Y,Ohayon E

更新日期：2000-01-01 00:00:00

abstract：:Although emerging evidence links mesenchymal stem cells (MSCs) with cancer metastasis, the underlying mechanisms are poorly understood. In the present study, we found that human umbilical cord-derived MSCs (UC-MSCs) promoted MCF-7 cell migration in vitro and metastasis in vivo. To explore the mechanisms, the character...

journal_title：Cell transplantation

authors： Ma F,Chen D,Chen F,Chi Y,Han Z,Feng X,Li X,Han Z

更新日期：2015-01-01 00:00:00

abstract：:Multiple sclerosis (MS) is a severe debilitating disorder characterized by progressive demyelination and axonal damage of the central nervous system (CNS). Current therapies for MS inhibit the immune response and demonstrate reasonable benefits if applied during the early phase of relapsing–remitting MS (RRMS) while t...

journal_title：Cell transplantation

authors： Cobo M,Anderson P,Benabdellah K,Toscano MG,Muñoz P,García-Pérez A,Gutierrez I,Delgado M,Martin F

更新日期：2013-01-01 00:00:00

abstract：:In this study, we assessed the ability of miR-26b-5p to regulate T cell factor 4 (TCF-4) expression and thereby control human adipose-derived mesenchymal stem cell (hADMSC) adipogenic differentiation. Adipogenic medium was used to induce hADMSC differentiation over a 6-d period. The ability of miR-26b-5p to interact w...

journal_title：Cell transplantation

authors： Luo Y,Ji H,Cao Y,Ding X,Li M,Song H,Li S,WaTableng C,Wu H,Meng J,Du H

更新日期：2020-01-01 00:00:00

abstract：:Transplantation therapies aimed at repairing neurodegenerative and neuropathological conditions of the central nervous system (CNS) have utilized and tested a variety of cell candidates, each with its own unique set of advantages and disadvantages. The use and popularity of each cell type is guided by a number of fact...

journal_title：Cell transplantation

authors： Kramer AS,Harvey AR,Plant GW,Hodgetts SI

更新日期：2013-01-01 00:00:00

abstract：:Future improvements in the recovery and function of pancreatic islets following cryopreservation will require a more precise quantification of the stresses that occur at each stage of the cryopreservation protocol. Changes in solution osmolality during the addition and dilution of cryoprotectants and during freezing a...

journal_title：Cell transplantation

authors： Zieger MA,Woods EJ,Lakey JR,Liu J,Critser JK

更新日期：1999-05-01 00:00:00

abstract：:Wharton's jelly-derived mesenchymal stromal cells (WJ-MSCs) have distinct immunomodulatory and protective effects against kidney, liver, or heart injury. Limited studies have shown that WJ-MSCs attenuates oxygen-glucose deprivation-mediated inflammation in hippocampal slices. The neuroprotective effect of intracerebra...

journal_title：Cell transplantation

authors： Wu KJ,Yu SJ,Chiang CW,Lee YW,Yen BL,Tseng PC,Hsu CS,Kuo LW,Wang Y

更新日期：2018-11-01 00:00:00

abstract：:Neurodegenerative disorders, chronic diseases that can severely affect the patient's daily life, include amyotrophic lateral sclerosis, Parkinson's, Alzheimer's, and Huntington's diseases. However, these diseases all have the common characteristic that they are due to degenerative irreversibility, and thus no efficien...

journal_title：Cell transplantation

authors： Chan TM,Chen JY,Ho LI,Lin HP,Hsueh KW,Liu DD,Chen YH,Hsieh AC,Tsai NM,Hueng DY,Tsai ST,Chou PW,Lin SZ,Harn HJ

更新日期：2014-01-01 00:00:00

abstract：:The cytology of peritoneal washing fluids for gastric cancer is the most basic method for judging peritoneal micrometastasis. However, the clinical value of this method is not clear at present. A retrospective analysis was performed on 277 patients with pathologically proven and surgically treated gastric cancer. The ...

journal_title：Cell transplantation

authors： Jiang RP,Xiong XJ,Qiu XS,Wang EH,Wu GP

更新日期：2019-11-01 00:00:00

abstract：:The third-generation NOD/LtSz-scid/IL2Rγ(null) (NOD/SCID IL2Rγ(null)) mouse represents a significantly improved xenograft model allowing high levels of human leukocyte engraftment over extended follow up. One remaining limitation of this mouse model, however, is the low level of circulating human erythrocytes. We esta...

journal_title：Cell transplantation

authors： Hayakawa J,Hsieh MM,Anderson DE,Phang O,Uchida N,Washington K,Tisdale JF

更新日期：2010-01-01 00:00:00

abstract：:Liver cell transplantation into host organs like the spleen may possibly provide a temporary relief after extensive liver resection or severe liver disease or may enable treatment of an enzyme deficiency. With time, however, dedifferentiation or malignant transformation of the ectopically transplanted cells may be pos...

journal_title：Cell transplantation

authors： Lupp A,Danz M,Müller D

更新日期：2003-01-01 00:00:00

abstract：:Human islet allografts are well known to induce full and sustained remission of hyperglycemia, with complete normalization of key metabolic parameters. Nevertheless, acquiring human islets, even from cadaveric human donor pancreases, remains a significant impediment to successful transplantation therapy for diabetes. ...

journal_title：Cell transplantation

authors： Luca G,Calvitti M,Nastruzzi C,Macchiarulo G,Becchetti E,Neri LM,Capitani S,Basta G,Brunetti P,Calafiore R,Cameron DF

更新日期：2006-01-01 00:00:00

abstract：:Adipose tissue contains a mesenchymal stem cell (MSC) population known as adipose-derived stem cells (ASCs) capable of differentiating into different cell types. Our aim was to induce hepatic transdifferentiation of ASCs by sequential exposure to several combinations of cytokines, growth factors, and hormones. The mos...

journal_title：Cell transplantation

authors： Bonora-Centelles A,Jover R,Mirabet V,Lahoz A,Carbonell F,Castell JV,Gómez-Lechón MJ

更新日期：2009-01-01 00:00:00

abstract：:Stem cell transplantation represents a promising therapeutic approach for myocardial ischemia/reperfusion (I/R) injury, where cortical bone-derived stem cells (CBSCs) stand out and hold superior cardioprotective effects on myocardial infarction than other types of stem cells. However, the molecular mechanism underlyin...

journal_title：Cell transplantation

authors： Li T,Su Y,Yu X,Mouniir DSA,Masau JF,Wei X,Yang J

更新日期：2018-08-01 00:00:00

abstract：:Human amniotic membrane (hAM) is the innermost layer of fetal membranes, which surrounds the developing fetus and forms the amniotic cavity. hAM and hAM-derived cells possess many properties that make them suitable for use in regenerative medicine, such as low immunogenicity, promotion of epithelization, anti-inflamma...

journal_title：Cell transplantation

authors： Ramuta TŽ,Kreft ME

更新日期：2018-01-01 00:00:00

abstract：:A large proportion of islets are lost after transplantation partly due to a lack of functional vasculature. Islets revascularize from host tissue but the process takes up to 2 weeks and has been suggested to result in reduced vascular density in engrafted islets. We describe a method for observing and quantifying the ...

journal_title：Cell transplantation

authors： Jones GL,Juszczak MT,Hughes SJ,Kooner P,Powis SH,Press M

更新日期：2007-01-01 00:00:00

abstract：:Recent advances in islet transplantation using highly purified islets and effective immunosuppression strategies have resulted in substantial improvement in achieving insulin independence in type 1 diabetes patients. However, there are side effects from long-term immunosuppression, and transplant rejection and/or the ...

journal_title：Cell transplantation

authors： Kobayashi N

更新日期：2008-01-01 00:00:00

abstract：:Head and neck squamous cell carcinoma (HNSCC) is a malignant tumor of the upper aerodigestive tract affecting the oral cavity, lips, paranasal sinuses, larynx, and nasopharynx. Proteogenomics combines proteomics and genomics and employs mass spectrometry and high-throughput sequencing technologies to identify novel pe...

journal_title：Cell transplantation

authors： Wu ZH,Yun-Tang,Cheng Q

更新日期：2020-01-01 00:00:00