Novel fluorescent protein from Hydnophora rigida possess cyano emission.

abstract：:Neural stem cells (NSCs) have the potential for differentiation into neurons known as a groundbreaking therapeutic solution for central nervous system (CNS) diseases. To resolve the therapeutic efficiency of NSCs, recent researchers have focused on the study on microRNA's role in CNS. Some micro RNAs have been reporte...

journal_title：Biochemical and biophysical research communications

authors： Song J,Cho KJ,Oh Y,Lee JE

更新日期：2015-07-10 00:00:00

abstract：:The budding yeast Saccharomyces cerevisiae contains a single actin gene and the gene product, actin, is essential for growth. Two mutants of yeast actin that do not support yeast growth were prepared from yeast by coexpressing the mutant and a 6-histidine-tagged wild-type actin followed by separation of the wild-type ...

journal_title：Biochemical and biophysical research communications

authors： Frieden C,Du J,Schriefer L,Buzan J

更新日期：2000-05-10 00:00:00

abstract：:Sorafenib may provide survival benefits for patients with advanced hepatocellular carcinoma. However, tumor cells can display primary or secondary resistance to Sorafenib. To identify genes capable of conveying Sorafenib resistance, we performed a genome-wide CRISPR transcriptional activation library (SAM) in human Hu...

journal_title：Biochemical and biophysical research communications

authors： Cai J,Chen J,Wu T,Cheng Z,Tian Y,Pu C,Shi W,Suo X,Wu X,Zhang K

更新日期：2020-06-11 00:00:00

abstract：:We report the construction of a cDNA clone encoding a functional GM2-activator protein. The sequence of the complete 5' end of the coding region was determined by direct nucleotide sequencing of a fragment generated by multiple RACE PCR procedures from Hela cell cDNA. Specific oligonucleotides were synthesized from th...

journal_title：Biochemical and biophysical research communications

authors： Xie B,McInnes B,Neote K,Lamhonwah AM,Mahuran D

更新日期：1991-06-28 00:00:00

abstract：:Insulin-like growth factor-II (IGF-II) is a potent mitogen for cells in culture. The H19 gene is a developmentally regulated gene with putative tumor suppressor activity, and loss of H19 expression may be involved in tumorigenesis. The H19 gene is closely linked to the human IGF-II gene (IGF2) on chromosome 11p15.5 an...

journal_title：Biochemical and biophysical research communications

authors： Kiess W,Paquette J,Koepf G,Wolf E,Deal C

更新日期：1999-02-16 00:00:00

abstract：:The filamentous fungus Aspergillus ochraceus TS produces an inducible microsomal cytochrome P-450 linked monooxygenase which is capable of hydroxylating benzo(a)pyrene in presence of O2 and NADPH. The addition of Benzo(a)pyrene, 3-Methyl cholanthrene, beta-Naphthoflavone and other aryl hydrocarbons during the inductio...

journal_title：Biochemical and biophysical research communications

authors： Dutta D,Ghosh DK,Mishra AK,Samanta TB

更新日期：1983-09-15 00:00:00

abstract：:To date, tick-borne flaviviruses responsible for hemorrhagic fever in humans have been isolated in Siberia (Omsk hemorrhagic fever virus), India (Kyasanur Forest disease virus, KFDV), and in Saudi Arabia (Alkhurma virus, ALKV). Prior to this study, only partial coding sequences of these severe pathogens had been deter...

journal_title：Biochemical and biophysical research communications

authors： Charrel RN,Zaki AM,Attoui H,Fakeeh M,Billoir F,Yousef AI,de Chesse R,De Micco P,Gould EA,de Lamballerie X

更新日期：2001-09-21 00:00:00

abstract：:Cholesterol is a critical component of lipid rafts implicated in regulating multiple signal transduction. The anthrax toxin receptor 2 (ANTXR2) is a type I membrane protein acting as the second receptor for the anthrax toxin. In this study, we first investigated the association between cholesterol and ANTXR2. We provi...

journal_title：Biochemical and biophysical research communications

authors： Zou J,Xu L,Ju Y,Zhang P,Wang Y,Zhang B

更新日期：2014-09-12 00:00:00

abstract：:A fast and robust assay, based on the combination of the highly sensitive immuno-PCR (IPCR), employing standardized self-assembled DNA-protein conjugates as reagents, and the well-established, reliable, and fast real-time PCR detection by means of the TaqMan principle is introduced in this work. The use of anti-specie...

journal_title：Biochemical and biophysical research communications

authors： Adler M,Wacker R,Niemeyer CM

更新日期：2003-08-22 00:00:00

abstract：:The poly(rC)-binding protein PCBP2 has multiple functions in post-transcriptional control of host and viral gene expression. Since it interacts with picornaviral RNA structures, it was proposed that PCBP2 regulates viral genome translation and replication. The hepatitis A virus (HAV), an atypical picornavirus, contain...

journal_title：Biochemical and biophysical research communications

authors： Zhang B,Seitz S,Kusov Y,Zell R,Gauss-Müller V

更新日期：2007-12-28 00:00:00

abstract：:The green tea gallocatechins, (-)-epigallocatechin-3-O-gallate (EGCG) (IC(50) = 0.69 microM), (-)-gallocatechin-3-O-gallate (GCG) (IC(50) = 0.67 microM), (-)-epicatechin-3-O-gallate (ECG) (IC(50) = 1.3 microM), and theasinensin A (IC(50) = 0.13 microM), were found to be potent and selective inhibitors of rat squalene ...

journal_title：Biochemical and biophysical research communications

authors： Abe I,Seki T,Umehara K,Miyase T,Noguchi H,Sakakibara J,Ono T

更新日期：2000-02-24 00:00:00

abstract：:Transcriptional mechanisms controlling human UCP3 gene expression in skeletal muscle remain poorly understood. Experiments based on plasmid electrotransfer into tibialis anterior muscle of C57/BL6 male mice were set up in order to functionally analyze the hUCP3 gene promoter. These transfection experiments showed that...

journal_title：Biochemical and biophysical research communications

authors： Riquet FB,Rodriguez M,Guigal N,Dromaint S,Naime I,Boutin JA,Galizzi JP

更新日期：2003-11-21 00:00:00

abstract：:Human platelets contained proteins which cross-reacted with antisera specific for brain protein kinase C-alpha and -beta. When platelets were incubated with 12-O-tetradecanoylphorbol-13-acetate there was a rapid accumulation of protein kinase C-alpha in the particulate fraction associated with a loss of this subspecie...

journal_title：Biochemical and biophysical research communications

authors： Fournier A,Hardy SJ,Clark KJ,Murray AW

更新日期：1989-06-15 00:00:00

abstract：:In our previous studies, we have demonstrated that a stretch of amino-acid sequences identified from Arabidopsis ribosomal S6 kinase 1 (AtS6K1) provided a plant version of the TOS (TOR-signaling) motif, mediating the interaction with the Raptor protein in the TOR (Target of Rapamycin) kinase complex. Here we report th...

journal_title：Biochemical and biophysical research communications

authors： Son O,Kim S,Kim D,Hur YS,Kim J,Cheon CI

更新日期：2018-06-27 00:00:00

abstract：:The effect of phosphorylation by cyclic AMP dependent protein kinase on the assembly of the core-forming 68 KDa neurofilament subunit protein (NF-L) was studied in vitro by fluorescence energy transfer and electron microscopy. Phosphorylation of unassembled NF-L in a low ionic strength buffer by cyclic AMP dependent p...

journal_title：Biochemical and biophysical research communications

authors： Nakamura Y,Takeda M,Angelides KJ,Tanaka T,Tada K,Nishimura T

更新日期：1990-06-15 00:00:00

abstract：:Effects of the imidazoline compound RX871024 on cytosolic free Ca(2+) concentration ([Ca(2+)]i) and insulin secretion in pancreatic beta-cells from SUR1 deficient mice have been studied. In beta-cells from wild-type mice RX871024 increased [Ca(2+)]i by blocking ATP-dependent K(+)-current (K(ATP)) and inducing membrane...

journal_title：Biochemical and biophysical research communications

authors： Efanov AM,Høy M,Bränström R,Zaitsev SV,Magnuson MA,Efendic S,Gromada J,Berggren PO

更新日期：2001-06-22 00:00:00

abstract：:The use of dry Bacillus subtilis spores as a biological dosimeter for the monitoring of solar UV-B (290-330 nm) radiation was described. Our field tests had supported the utility of this dosimeter as a reproducible and reliable sunlight dosimeter. ...

journal_title：Biochemical and biophysical research communications

authors： Wang TC

更新日期：1991-05-31 00:00:00

abstract：:We report high resolution images of RecA-double stranded (ds) DNA complexes obtained by atomic force microscopy (AFM). When a carbon nanotube (CNT) tip was used, AFM images visualized the 10-nm pitch of RecA-dsDNA complexes and RecA filaments as three-dimensional surface topography without reconstruction analysis. The...

journal_title：Biochemical and biophysical research communications

authors： Umemura K,Komatsu J,Uchihashi T,Choi N,Ikawa S,Nishinaka T,Shibata T,Nakayama Y,Katsura S,Mizuno A,Tokumoto H,Ishikawa M,Kuroda R

更新日期：2001-02-23 00:00:00

abstract：:Dengue Virus (DENV) infection is an important mosquito-borne viral disease and its clinical symptoms range from a predominantly febrile disease, dengue fever (DF), to dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). Increased levels of cytokines - the so-called 'cytokine storm', contribute to the pathog...

journal_title：Biochemical and biophysical research communications

authors： Suttitheptumrong A,Khunchai S,Panaampon J,Yasamut U,Morchang A,Puttikhunt C,Noisakran S,Haegeman G,Yenchitsomanus PT,Limjindaporn T

更新日期：2013-06-28 00:00:00

abstract：:We have used HL-60 leukemia cells to investigate phosphatidylinositol 3-kinase (PI 3-K) during granulocytic differentiation at the nuclear level. Nuclei of HL-60 cells showed a constitutive presence of PI 3-K that increased when cells were treated with differentiating doses of ATRA. PI 3-K was also detected tightly bo...

journal_title：Biochemical and biophysical research communications

authors： Marchisio M,Bertagnolo V,Colamussi ML,Capitani S,Neri LM

更新日期：1998-12-18 00:00:00

abstract：:Recently, we reported that Lumbricusin, an antimicrobial peptide isolated from earthworm Lumbricus terrestris, enhanced neuronal proliferation and ameliorated motor dysfunction and dopaminergic neurodegeneration. Accumulating evidence suggests that neurodegeneration is the primary pathological feature of acute or chro...

journal_title：Biochemical and biophysical research communications

authors： Seo M,Lee JH,Baek M,Kim MA,Ahn MY,Kim SH,Yun EY,Hwang JS

更新日期：2017-08-26 00:00:00

abstract：:Here we have investigated the function of TcRho1, a Rho family orthologue from the parasite Trypanosoma cruzi. We have selected parasites overexpressing wild-type TcRho1 and a truncated form of TcRho1 (TcRho1-DeltaCaaX) which is unable to undergo farnesylation and supposed to interfere with recruitment of Rho effector...

journal_title：Biochemical and biophysical research communications

authors： de Melo LD,Nepomuceno-Silva JL,Sant'Anna C,Eisele N,Ferraro RB,Meyer-Fernandes JR,de Souza W,Cunha-e-Silva NL,Lopes UG

更新日期：2004-10-22 00:00:00

abstract：:The Znf131/ZNF131 protein belongs to the superfamily of POK proteins containing a BTB/POZ domain in its N-terminal part and 5 typical C2H2 zinc fingers and an additional C2HC zinc finger structure in its C-terminal region. In mouse and human two alternatively spliced transcripts are expressed from the Znf131/ZNF131 ge...

journal_title：Biochemical and biophysical research communications

authors： Trappe R,Buddenberg P,Uedelhoven J,Gläser B,Buck A,Engel W,Burfeind P

更新日期：2002-08-16 00:00:00

abstract：:Hepatocellular carcinoma (HCC) tumors evade death in part by downregulating expression of the tumor suppressor gene Interferon regulatory factor-1 (IRF-1). However, the molecular mechanisms accounting for IRF-1 suppression in HCC have not been well described. In this study, we identified a novel microRNA-301a (miR-301...

journal_title：Biochemical and biophysical research communications

authors： Dong K,Du Q,Cui X,Wan P,Kaltenmeier C,Luo J,Yan B,Yan Y,Geller DA

更新日期：2020-04-02 00:00:00

abstract：:In our previous study, the novel GRN-41 peptide generated from alternative splicing of the Mozambique tilapia PGRN1 gene was identified to be a potent peptide that protected against V. vulnificus in the transgenic zebrafish model by modulating innate immune-related genes. In this study, the anti-bacterial activities o...

journal_title：Biochemical and biophysical research communications

authors： Wu SH,Chou HY,Liu PC,Wu JL,Gong HY

更新日期：2019-08-06 00:00:00

abstract：:Sf9 cells infected with the recombinant mouse CaMKII-alpha (Ca2+/calmodulin dependent kinase II) baculovirus expressed 12-15 mg of MCaMKII-alpha per liter of cells. Approximately 50% of the MCaMKII-alpha activity could be purified using a CaM-Sepharose affinity column. The purified MCaMKII-alpha had a M(rapp) of 50 kD...

journal_title：Biochemical and biophysical research communications

authors： Brickey DA,Colbran RJ,Fong YL,Soderling TR

更新日期：1990-12-14 00:00:00

abstract：:The phosphonodifluoromethyl phenylalanine (F2Pmp) is superior to phosphonomethyl phenylalanine (Pmp) as a non-hydrolyzable phosphotyrosine (pTyr) mimetic. The difluoromethyl moiety increases the inhibitory potency of a F2Pmp-containing peptide over a Pmp-containing counterpart by 1000-fold toward the protein tyrosine ...

journal_title：Biochemical and biophysical research communications

authors： Chen L,Wu L,Otaka A,Smyth MS,Roller PP,Burke TR Jr,den Hertog J,Zhang ZY

更新日期：1995-11-22 00:00:00

abstract：:Inhibition experiments with D-mannose oligosaccharides establish that conglutinin recognises terminal alpha 1----2 mannobiosyl units present in the glycopeptide of the alpha-chain of the complement component C3b. On the basis of its three domain structure and the homology of its N-terminal amino-acid sequence to that ...

journal_title：Biochemical and biophysical research communications

authors： Young NM,Leon MA

更新日期：1987-03-13 00:00:00

abstract：:Thioredoxin (TRX) is one of major components of thiol reducing systems. To investigate the molecular mechanism of TRX function in the lung tissue, we screened a human lung epithelial cell cDNA library for TRX-binding protein by yeast two-hybrid systems. We isolated a plasmid containing C-propeptide region of human pro...

journal_title：Biochemical and biophysical research communications

authors： Matsumoto K,Masutani H,Nishiyama A,Hashimoto S,Gon Y,Horie T,Yodoi J

更新日期：2002-07-19 00:00:00

abstract：:The inhibitory effect of mercapto- and chlorodicarbanonaborates on mitochondrial, FAD-linked, L-glycerol-3-phosphate dehydrogenase activity was tested. The mercaptodicarbanonaborate was found to be a more potent inhibitor than the chloro derivative. The Ki of mercapto- and chlorodicarbanonaborates were 0.8 M and 480 M...

journal_title：Biochemical and biophysical research communications

authors： Drahota Z,Saf P,Rauchová H,Kalous M

更新日期：1995-05-25 00:00:00