TcRho1 of Trypanosoma cruzi: role in metacyclogenesis and cellular localization.

abstract：:The D protein (16 kDa) is part of a protein core, common to U1, U2, U5, U4/U6 small nuclear RNA containing ribonucleoprotein particles. Monoclonal antibodies reactive with the D protein were used in quantitative dot blotting and Western blotting to demonstrate that this protein was a component of salt resistant nuclea...

journal_title：Biochemical and biophysical research communications

authors： Harris SG,Smith HC

更新日期：1988-05-16 00:00:00

abstract：:Migration of surviving kidney tubule cells after sub-lethal injury, for example ischemia/reperfusion (I/R), plays a critical role in recovery. Exocytosis is known to be involved in cell migration, and a key component in exocytosis is the highly-conserved eight-protein exocyst complex. We investigated the expression of...

journal_title：Biochemical and biophysical research communications

authors： Noh MR,Jang HS,Song DK,Lee SR,Lipschutz JH,Park KM,Kim JI

更新日期：2018-02-05 00:00:00

abstract：:The proper development of the cerebral cortex is essential for brain formation and functioning. O-GlcNAcylation, an important posttranslational modification, regulates the pathways critical for neuronal health and the survival of the cerebral cortex in neurodegenerative diseases. However, the role of O-GlcNAcylation i...

journal_title：Biochemical and biophysical research communications

authors： Cheng J,Wu Y,Chen L,Li Y,Liu F,Shao J,Huang M,Fan M,Wu H

更新日期：2020-11-19 00:00:00

abstract：:This study was designed to investigate the protective effect of the autophagy signaling pathway against Mycobacterium tuberculosis infection in type II alveolar epithelial cells. An in vitro M. tuberculosis system was established using human A549 cells. Infection-induced changes in the expression of the autophagic mar...

journal_title：Biochemical and biophysical research communications

authors： Guo XG,Ji TX,Xia Y,Ma YY

更新日期：2013-03-08 00:00:00

abstract：:It is considered that the essence of acute lung injury (ALI) is an excessive and uncontrolled inflammatory response in lung, of which mainly is attributed to the release of inflammatory mediators. Recent studies demonstrated that irisin, which is a metabolism associated factor after physical exercise could suppression...

journal_title：Biochemical and biophysical research communications

authors： Shao L,Meng D,Yang F,Song H,Tang D

更新日期：2017-05-27 00:00:00

abstract：:The tissue inhibitors of metalloproteinases (TIMPs) are specific inhibitors of MMP enzymatic activity. However, TIMP-2 can promote the activation of pro-MMP-2 by MT1-MMP. This process is mediated by the formation of a complex between MT1-MMP, TIMP-2, and pro-MMP-2. Binding of TIMP-2 to active MT1-MMP also inhibits the...

journal_title：Biochemical and biophysical research communications

authors： Hernandez-Barrantes S,Shimura Y,Soloway PD,Sang QA,Fridman R

更新日期：2001-02-16 00:00:00

abstract：:Sensory transduction in the cochlea depends on regulated ion secretion and absorption. Results of whole-organ experiments suggested that Reissner's membrane may play a role in the control of luminal Cl(-). We tested for the presence of Cl(-) transport pathways in isolated mouse Reissner's membrane using whole-cell pat...

journal_title：Biochemical and biophysical research communications

authors： Kim KX,Marcus DC

更新日期：2010-04-02 00:00:00

abstract：:VMA1 translational product undergoes excision of a 50-kDa intervening segment (VDE: VMA1-derived endonuclease) and religation of the flanking regions to create a 69-kDa catalytic subunit of vacuolar membrane H+-ATPase. VDEs conjugated with polypeptides at both N- and C-terminal ends were expressed in Escherichia coli ...

journal_title：Biochemical and biophysical research communications

authors： Kawasaki M,Makino S,Matsuzawa H,Satow Y,Ohya Y,Anraku Y

更新日期：1996-05-24 00:00:00

abstract：:Lymph node metastasis (LNM) is a critical cause for disease progression and treatment failure in cervical cancer. However, the mechanism underlying cervical cancer LNM remains unclear. In this study, HN1 was found to be dramatically upregulated in cervical cancer and patients with higher HN1 expression are more likely...

journal_title：Biochemical and biophysical research communications

authors： Chen J,Qiu J,Li F,Jiang X,Sun X,Zheng L,Zhang W,Li H,Wu H,Ouyang Y,Chen X,Lin C,Song L,Zhang Y

更新日期：2020-09-10 00:00:00

abstract：:Membrane lipid peroxidation is known to produce various aldehydic compounds which cause a wide range of biological effects including heart disease, aging, and cancer. To investigate the effect of lipid peroxidation products on the expression of glutathione S-transferases (GSTs), which catalyze the conjugation of react...

journal_title：Biochemical and biophysical research communications

authors： Fukuda A,Nakamura Y,Ohigashi H,Osawa T,Uchida K

更新日期：1997-07-18 00:00:00

abstract：:We have previously reported that RhoE is overexpressed in the SGC7901/VCR cell line. However, the potential role of RhoE in the development of multidrug resistance of gastric cancer is unknown. In the present study, RhoE enhanced the resistance of SGC7901 cells to several kinds of antitumor drugs. RhoE overexpression ...

journal_title：Biochemical and biophysical research communications

authors： Li K,Lu Y,Liang J,Luo G,Ren G,Wang X,Fan D

更新日期：2009-02-06 00:00:00

abstract：:Pathological cardiac hypertrophy, often accompanied by hypertension, aortic stenosis and valvular defects, is typically associated with myocyte remodeling and cardiac dysfunction. Exercise preconditioning (EP) has been proven to enhance the tolerance of the myocardium to cardiac ischemia-reperfusion injury. However, t...

journal_title：Biochemical and biophysical research communications

authors： Xu T,Zhang B,Yang F,Cai C,Wang G,Han Q,Zou L

更新日期：2015-05-08 00:00:00

abstract：:The role of nutritional factors during CryIVA protoxin expression in Bacillus thuringiensis israelensis (Bti) has been investigated. Inorganic phosphate (Pi) was found to stimulate 135 kD protoxin synthesis by Bti cells. There was a corresponding increase in the cryIVA specific mRNA in the presence of Pi. Inorganic ph...

journal_title：Biochemical and biophysical research communications

authors： Banerjee-Bhatnagar N

更新日期：1999-08-27 00:00:00

abstract：:Lanosterol synthase [(S)-2,3-epoxysqualene mutase (cyclizing, lanosterol forming), EC 5.4.99.7] catalyzes the cyclization of (S)-2,3-oxidosqualene to lanosterol in the reaction that forms the sterol nucleus. We report herein the cloning and characterization of the human gene (OSC) encoding lanosterol synthase, a predi...

journal_title：Biochemical and biophysical research communications

authors： Baker CH,Matsuda SP,Liu DR,Corey EJ

更新日期：1995-08-04 00:00:00

abstract：:Hepatic fibrosis can be considered as wound healing process in response to hepatocellular injury. Activation of hepatic stellate cells (HSCs) is a key event of hepatic fibrosis since activated HSCs are the cellular source of enhanced extracellular matrix deposition, and reversion of liver fibrosis is accompanied by cl...

journal_title：Biochemical and biophysical research communications

authors： Valletta D,Czech B,Thasler WE,Müller M,Bosserhoff AK,Hellerbrand C

更新日期：2012-09-28 00:00:00

abstract：:The two zinc fingers of the DNA binding domain of the human retinoic acid receptor-beta were labelled with 113Cd. Two- and three-dimensional heteronuclear nuclear magnetic resonance (NMR) experiments show that the first eight conserved cysteine residues coordinate the two zinc ions tetrahedrally. The ninth conserved c...

journal_title：Biochemical and biophysical research communications

authors： Knegtel RM,Boelens R,Ganadu ML,George AV,van der Saag PT,Kaptein R

更新日期：1993-04-30 00:00:00

abstract：:Various subclasses of messenger ribonucleoprotein particles were prepared from free cytoplasmic and polysome fractions of rat liver on the basis of the homopolymeric content of the constituent RNA's. Two major proteins were evident in the free cytoplasmic preparations: the poly(A)-binding protein was the major constit...

journal_title：Biochemical and biophysical research communications

authors： Ford G,Nichols JL

更新日期：1984-05-16 00:00:00

abstract：:We tested usefulness of a target enrichment system SureSelect, a comprehensive viral nucleic acid detection method, for rapid identification of viral pathogens in feces samples of cattle, pigs and goats. This system enriches nucleic acids of target viruses in clinical/field samples by using a library of biotinylated R...

journal_title：Biochemical and biophysical research communications

authors： Oba M,Tsuchiaka S,Omatsu T,Katayama Y,Otomaru K,Hirata T,Aoki H,Murata Y,Makino S,Nagai M,Mizutani T

更新日期：2018-01-08 00:00:00

abstract：:The regulated secretory pathway is a specialized form of protein secretion found in endocrine and neuroendocrine cell types. Pro-opiomelanocortin (POMC) is a pro-hormone that utilizes this pathway to be trafficked to dense core secretory granules (DCSGs). Within this organelle, POMC is processed to multiple bioactive ...

journal_title：Biochemical and biophysical research communications

authors： Dirk BS,End C,Pawlak EN,Van Nynatten LR,Jacob RA,Heit B,Dikeakos JD

更新日期：2018-12-09 00:00:00

abstract：:The tissue targeting and rate of clearance of cobra venom factor (CVF) from the circulation was studied in mice by intravenous or intraperitoneal injection of radioiodinated CVF. In both modes of administrations, CVF was targeted mainly to liver. CVF injected directly into the blood was cleared from the circulation wi...

journal_title：Biochemical and biophysical research communications

authors： Fu Q,Satyaswaroop PG,Gowda DC

更新日期：1997-02-13 00:00:00

abstract：:One of the biological effects of hyperbaric oxygen (HBO) therapy in enhancing ischemia-related wound healing is the induction of angiogenesis. To elucidate the mechanism(s) underlying the HBO-induced angiogenesis, we studied the expression of several angiogenesis-related genes in human umbilical vein endothelial cells...

journal_title：Biochemical and biophysical research communications

authors： Lin S,Shyu KG,Lee CC,Wang BW,Chang CC,Liu YC,Huang FY,Chang H

更新日期：2002-08-23 00:00:00

abstract：:The molecular structures of enzyme mimics may be modified to optimize their catalytic properties. In this study, to generate artificial enzyme mimics, Watson-Crick base paired DNA duplexes were designed as scaffolds which were assembled by nucleotides modified with specific functional groups. This process allowed vari...

journal_title：Biochemical and biophysical research communications

authors： Xu L,Ji C,Bai Y,He J,Liu K

更新日期：2013-05-10 00:00:00

abstract：:It is well-known that electrical stimulation can prompt healing of bone fractures. However, the mechanism involved is less clear. In this study, we found that capacitively coupled electric field-induced proliferation of osteoblastic cells (MC3T3-E1) accompanied increased levels of transforming growth factor-beta 1 (TG...

journal_title：Biochemical and biophysical research communications

authors： Zhuang H,Wang W,Seldes RM,Tahernia AD,Fan H,Brighton CT

更新日期：1997-08-18 00:00:00

abstract：:PAF (0.2 microM) induced maximal platelet aggregation in human PRP and [3H]-PAF (1-5 nM) binding to platelet membrane preparations had Kd value of 3.8 nM and Bmax of 200 fmoles/mg of protein. Without UV irradiation, a synthetic azido tetrahydrofuran derivative L662,025 was a reversible and competitive PAF-receptor ant...

journal_title：Biochemical and biophysical research communications

authors： Hussaini IM,Shen TY

更新日期：1989-05-30 00:00:00

abstract：:Avian leukosis virus (ALV) is one of the main causative agent of tumor development, which brings enormous economic losses to the poultry industry worldwide. ALV can be transmitted horizontally and vertically, and the latter often give rise to more adverse pathogenicity. However, the propagation and evolution of ALV un...

journal_title：Biochemical and biophysical research communications

authors： Gao X,Li Q,Fang L,Song H,Cui Z,Meng F,Zhang Z

更新日期：2020-01-22 00:00:00

abstract：:The reactivation of mitochondrial ATPase by acidic and isoelectric phospholipids was studied comparatively with two purified enzyme preparations exhibiting different gel electrophoretic patterns: the preparation of Serrano et al. (1976, J. Biol. Chem. 251, 2453-2461) and the complex V of Galante et al. (1979, J. Biol....

journal_title：Biochemical and biophysical research communications

authors： Dabbeni-Sala F,Palatini P

更新日期：1985-12-17 00:00:00

abstract：:cDNA microarray analyses can be used to identify candidate genes that play important roles in human carcinogenesis. To gain insight into the molecular sketch of colorectal cancer, we have constructed cDNA microarrays specialized for colorectal cancer, which we named "Colonochip" by selecting genes that are expressed i...

journal_title：Biochemical and biophysical research communications

authors： Takemasa I,Higuchi H,Yamamoto H,Sekimoto M,Tomita N,Nakamori S,Matoba R,Monden M,Matsubara K

更新日期：2001-08-03 00:00:00

abstract：:Under many physiological circumstances, Na(+)- and Cl(-)-dependent, hemicholinium-3 (HC-3)-sensitive, high-affinity choline uptake (HACU) in cholinergic neurons is thought to be rate-limiting in the biosynthesis of acetylcholine (ACh). Based on sequence information provided by the Human Genome Project and the recently...

journal_title：Biochemical and biophysical research communications

authors： Apparsundaram S,Ferguson SM,George AL Jr,Blakely RD

更新日期：2000-10-05 00:00:00

abstract：:Human prostasin was recently identified as a potential regulator of epithelial sodium channel (ENaC) function. Through the use of positional scanning combinatorial substrate libraries, prostasin was shown to have a preference for poly-basic substrates: in position P4 preference was for arginine or lysine; in P3 prefer...

journal_title：Biochemical and biophysical research communications

authors： Shipway A,Danahay H,Williams JA,Tully DC,Backes BJ,Harris JL

更新日期：2004-11-12 00:00:00

abstract：:In this study we examined the influence on AlF4- and GTP gamma S on amylase secretion from alpha toxin permeabilized pancreatic acini. AlF4- only activates heterotrimeric G-proteins, whereas GTP gamma S activates both small ras-like GTP-binding proteins and heterotrimeric G-proteins (Kahn, R. A., J. Biol. Chem., 266, ...

journal_title：Biochemical and biophysical research communications

authors： Padfield PJ,Panesar N

更新日期：1998-04-17 00:00:00