The carbohydrate specificity of conglutinin and its homology to proteins in the hepatic lectin family.

Abstract:

:Inhibition experiments with D-mannose oligosaccharides establish that conglutinin recognises terminal alpha 1----2 mannobiosyl units present in the glycopeptide of the alpha-chain of the complement component C3b. On the basis of its three domain structure and the homology of its N-terminal amino-acid sequence to that of the dog pulmonary surfactant protein, it is proposed that conglutinin is a member of the hepatic lectin family.

authors

Young NM,Leon MA

doi

10.1016/0006-291x(87)91402-1

subject

Has Abstract

pub_date

1987-03-13 00:00:00

pages

645-51

issue

2

eissn

0006-291X

issn

1090-2104

pii

0006-291X(87)91402-1

journal_volume

143

pub_type

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