Abstract:
:Norepinephrine and dopamine are both believed to affect signal-to-noise in the cerebral cortex. Dopaminergic agents appear to modulate semantic networks during indirect semantic priming, but do not appear to affect problem solving dependent on access to semantic networks. Noradrenergic agents, though, do affect semantic network dependent problem solving. We wished to examine whether noradrenergic agents affect indirect semantic priming. Subjects attended three sessions: one each after propranolol (40 mg) (noradrenergic antagonist), ephedrine (25 mg) (noradrenergic agonist), and placebo. During each session, closely related, distantly related, and unrelated pairs were presented. Reaction times for a lexical decision task on the target words (second word in the pair) were recorded. No decrease in indirect semantic priming occurred with ephedrine. Furthermore, across all three drugs, a main effect of semantic relatedness was found, but no main effect of drug, and no drug/semantic relatedness interaction effect. These findings suggest that noradrenergic agents, with these drugs and at these doses, do not affect indirect semantic priming with the potency of dopaminergic drugs at the doses previously studied. In the context of this previous work, this suggests that more automatic processes such as priming and more controlled searches of the lexical and semantic networks such as problem solving may be mediated, at least in part, by distinct mechanisms with differing effects of pharmacological modulation.
journal_name
Behav Neuroljournal_title
Behavioural neurologyauthors
Cios JS,Miller RF,Hillier A,Tivarus ME,Beversdorf DQdoi
10.3233/BEN-2009-0236subject
Has Abstractpub_date
2009-01-01 00:00:00pages
137-43issue
3eissn
0953-4180issn
1875-8584pii
Q40H6077J4887X1Ljournal_volume
21pub_type
杂志文章abstract:BACKGROUND:Tacrolimus-associated encephalopathy (TAC-E) is usually described under the term of posterior reversible encephalopathy syndrome (PRES). However, a large amount of data has suggested that TAC-E is not a homogenous entity: indeed, TAC-E which is often presented with atypical and potentially misleading imaging...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2014/931808
更新日期:2014-01-01 00:00:00
abstract::We report findings from a cognitive neuropsychological and psychophysiological investigation of a patient who displayed an exacerbated acute emotional expression during movement, innocuous, and aversive somatosensory stimulation. The condition developed in the context of non-specific white matter ischaemia along with ...
journal_title:Behavioural neurology
pub_type: 临床试验,杂志文章
doi:10.1155/2004/458327
更新日期:2004-01-01 00:00:00
abstract::Communication in humans activates almost every part of the brain. Of course, the use of language predominates, but other cognitive functions such as attention, memory, emotion, and executive processes are also involved. However, in order to explain how our brain "understands," "speaks," and "writes," and in order to r...
journal_title:Behavioural neurology
pub_type: 杂志文章,评审
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更新日期:2019-07-22 00:00:00
abstract::Two experiments examined short-term memory for order information in six patients diagnosed with Parkinson's disease (PD) and six control subjects while event related potentials (ERPs) were recorded. The subjects were tested for recognition of abstract spatial designs and words after a 5 s retention interval. The PD pa...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.3233/BEN-1996-9203
更新日期:1996-01-01 00:00:00
abstract::Primary sexual dysfunctions (SD) are a direct result of neurological changes that affect the sexual response. Secondary SD result from the symptoms that do not directly involve nervous pathways to the genital system, such as bladder and bowel problems, fatigue, spasticity, or muscle weakness. Tertiary SD are the resul...
journal_title:Behavioural neurology
pub_type: 杂志文章
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journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.3233/BEN-2010-0267
更新日期:2010-01-01 00:00:00
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journal_title:Behavioural neurology
pub_type: 杂志文章
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journal_title:Behavioural neurology
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doi:10.1155/2008/157356
更新日期:2008-01-01 00:00:00
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journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.3233/BEN-1997-10103
更新日期:1997-01-01 00:00:00
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journal_title:Behavioural neurology
pub_type: 杂志文章
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更新日期:2020-08-07 00:00:00
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journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.3233/BEN-1992-5204
更新日期:1992-01-01 00:00:00
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journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2004/409248
更新日期:2004-01-01 00:00:00
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journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2018/8929735
更新日期:2018-01-17 00:00:00
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journal_title:Behavioural neurology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1155/2017/5919841
更新日期:2017-01-01 00:00:00
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journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/1998/617160
更新日期:1998-01-01 00:00:00
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journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2019/7694503
更新日期:2019-02-12 00:00:00
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journal_title:Behavioural neurology
pub_type: 杂志文章,评审
doi:10.1155/2017/3731802
更新日期:2017-01-01 00:00:00
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journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.3233/BEN-1994-7204
更新日期:1994-01-01 00:00:00
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journal_title:Behavioural neurology
pub_type: 杂志文章,评审
doi:10.1155/2006/793256
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journal_title:Behavioural neurology
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.3233/BEN-1997-10401
更新日期:1997-01-01 00:00:00
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journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/2018/9684129
更新日期:2018-04-01 00:00:00
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journal_title:Behavioural neurology
pub_type: 杂志文章,评审
doi:10.3233/BEN-2009-0230
更新日期:2009-01-01 00:00:00
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journal_title:Behavioural neurology
pub_type: 杂志文章,评审
doi:10.1155/2014/641213
更新日期:2014-01-01 00:00:00
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journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.3233/BEN-1990-3206
更新日期:1990-01-01 00:00:00
abstract::While several studies have detected raised levels of neurological soft signs in patients with obsessive compulsive disorder (OCD), the specificity of these abnormalities remains uncertain. This study used a new standardised measure, the Cambridge Neurological Inventory (CNI), to assess soft signs in 51 subjects with O...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.1155/1999/639045
更新日期:1998-01-01 00:00:00
abstract::Since the Korean language has two distinct writing systems, phonogram (Hangul) and ideogram (Hanja: Chinese characters), alexia can present with dissociative disturbances in reading between the two systems. A 74-year-old right-handed man presented with a prominent reading impairment in Hangul with agraphia of both Han...
journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.3233/BEN-2008-0211
更新日期:2008-01-01 00:00:00
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journal_title:Behavioural neurology
pub_type: 杂志文章
doi:10.3233/BEN-1993-6304
更新日期:1993-01-01 00:00:00